A method is described for the computer simulation of mammograms. Software has been developed to model the conversion of input X-ray quanta to visible light photons inside a phosphor screen. In this method, we separated the physics processes that convert X-ray quanta to visible light photons inside a fluorescent screen into five mathematical transformations. Standard FFT techniques were used. We extended Swank's one-dimensional fluorescent screen MTF model into a two-dimensional photon diffusion model by solving the 2D Boltzman diffusion equation. The simulation software divides the fluorescent screen into multiple thinner sub-layers and integrates the visible light output of every sub-layer over the whole screen into the final image. The simulation software was tested by two comparisons: modulation transfer function (MTF) and noise power spectrum. Both test results show that the method and the simulation software work correctly. For the modulation transfer function and the shape of the noise power spectra, the difference between the simulation and the experimental values of an actual fluorescent screen was within 8%. Qualitatively, the simulated and actual images of test objects looked similar. Using the developed method, we will be able to produce simulated mammograms that can be used to evaluate computer-aided diagnosis (CAD) methods and techniques.
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