Due to the phenomenon of mixed pixels in low-resolution remote sensing images, the green tide spectral features with low Enteromorpha coverage are not obvious. Super-resolution technology based on deep learning can supplement more detailed information for subsequent semantic segmentation tasks. In this paper, a novel green tide extraction method for MODIS images based on super-resolution and a deep semantic segmentation network was proposed. Inspired by the idea of transfer learning, a super-resolution model (i.e., WDSR) is first pre-trained with high spatial resolution GF1-WFV images, and then the representations learned in the GF1-WFV image domain are transferred to the MODIS image domain. The improvement of remote sensing image resolution enables us to better distinguish the green tide patches from the surrounding seawater. As a result, a deep semantic segmentation network (SRSe-Net) suitable for large-scale green tide information extraction is proposed. The SRSe-Net introduced the dense connection mechanism on the basis of U-Net and replaces the convolution operations with dense blocks, which effectively obtained the detailed green tide boundary information by strengthening the propagation and reusing features. In addition, the SRSe-Net reducs the pooling layer and adds a bridge module in the final stage of the encoder. The experimental results show that a SRSe-Net can obtain more accurate segmentation results with fewer network parameters.