Conclusion: The endoscopic modified Lothrop procedure was found to be useful for management of postoperative frontal mucocele. Objective: The aim of this study was to evaluate the efficacy of the endoscopic modified Lothrop procedure, in which bone resection in the lateral aspect of the frontal recess and frontonasal duct was avoided, for management of postoperative frontal mucocele. Patients and methods: The study prospectively assessed six patients who underwent an endoscopic modified Lothrop procedure. Patients had undergone a mean of two previous sinus surgical procedures. In our procedure, the mucosa and bone of the lateral aspect of the frontal recess and frontonasal duct were preserved, while a median drainage in the frontal sinus floor was created as large as possible. Results: All patients had a patent median drainage pathway and were free from preoperative symptoms with an average follow-up of 24.5 months. Although scar formation in the anterior aspects of the frontal recess was observed, no patients required revision surgery.