Purpose of Study: This study evaluates the Gradient-Based Dynamic Levy Flight Cuckoo Search Optimization (MCSO-DLF) for breast cancer detection and compares it to six established optimization algorithms. The goal is to determine if MCSO-DLF offers higher accuracy and computational efficiency for optimizing diagnostic models. Methodology: The study compares MCSO-DLF with PSO, GA, ACO, SA, DE, and ABC using the Breast Cancer Wisconsin dataset. The algorithms are evaluated based on accuracy, convergence speed, and efficiency. MCSO-DLF uses dynamic Levy flight and gradient-based optimization to improve solution quality. Main Findings: MCSO-DLF achieved the highest accuracy (0.9912) and fastest computation time (65.94 seconds), outperforming all other algorithms. This demonstrates its effective balance between exploration and local solution refinement. Implications: MCSO-DLF significantly improves accuracy and speed, offering potential advancements in breast cancer detection systems, leading to better patient outcomes and more efficient healthcare. Novelty of Study: This study introduces MCSO-DLF as a novel hybrid optimization method that combines gradient-based optimization with dynamic Levy flight, outperforming traditional algorithms in complex medical diagnostics.
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