In 12 tested subjects, we studied changes in the frequency-amplitude EEG characteristics evoked by thermostimulation of the left palm (its immersion in a pool of water with a changing temperature); temperatures of 24 and 42°C provided cooling and heating stimulations. Cooling of the palm resulted in an increase of the power of fast EEG oscillations, especially in the parietal and occipital regions and in the right temporal zone. Heating of the palm skin evoked an increase in the power of α- and θ-waves, and the latter component was most noticeably intensified in the frontal and right temporal regions. Possible mechanisms responsible for EEG modifications under conditions of thermostimulation of the skin are discussed.