Modern Preventive Medicine Research Articles

George N. Papanicolaou (1883-1962): The Pioneer of Cytology and Early Cancer Detection.

George N. Papanicolaou (1883-1962) is recognized as a pioneer in cytology and early cancer detection, whose groundbreaking work revolutionized women's healthcare. His development of the Pap smear, a simple yet powerful screening tool, dramatically improved the early diagnosis of cervical cancer, leading to a significant reduction in mortality rates and saving millions of lives worldwide. Born in Greece and extensively trained in medicine and biology, Papanicolaou conducted meticulous research at Cornell University, laying the foundation for modern preventive medicine. This historical vignette explores Papanicolaou's life, transformative achievements, and the innovative processes he championed. By examining his enduring contributions, we highlight his profound impact on public health and medical practice, which continues to inspire and guide healthcare professionals across generations.

Analysis of the relationship between actual nutrition and physical activity and smoking among russian and foreign students of a medical university

A significant contribution to the preservation and improvement of the population health is made by a healthy lifestyle, one of the components of which is rational nutrition. Considering severe stress experienced by students due to the changed social environment, the study of nutritional characteristics and the role of behavioral factors in eating behavior among medical students remains an extremely topical issue of modern preventive medicine. Material and methods. As a result of a cross-sectional study, 197 students of the Saratov Medical University were interviewed, 100 (51 %) of them were russian students, 97 (49 %) were citizens of Central African countries. The method of 24-hour reproduction of daily diet, program complex “Individual diet 5.0 professional version”, questionnaire were used. Results and discussions. The study showed an imbalance in macro- and micronutrients intake of the daily food ration, a violation in the diet, insufficient consumption of vegetables and fruits, rare hot meals, dissatisfaction with the organization of meals in student canteens, frequent use of fast food by students regardless of their country of origin. The relationship of physical activity and smoking with the diet and the frequency of consumption of vegetables and fruits, low awareness of unbalanced nutrition as a risk factor for the development of alimentary-dependent diseases have been established. Conclusions. The nutritional behavior of russian and foreign students of Saratov Medical University does not meet all the principles of healthy eating recommended by WHO. Thus, it is necessary to improve the organization of catering in student canteens, taking into account the taste preferences of foreign students, the introduction of educational activities and healthy nutrition programs with the involvement of the students themselves in their preparation. The analysis of actual nutrition is a very important task, as it allows assessing the current socio-economic situation, as well as the effectiveness of educational programs in the framework of national projects on a healthy lifestyle and proper nutrition.

Результати оцінки безпечності для споживачів добавки дієтичної «Тайро Ультра», створеної для підтримки нормальної функції щитоподібної залози

In recent years, Ukraine has seen an increase in consumer interest in dietary supplements made on the basis of traditional Ayurvedic recipes and containing natural organic-mineral complexes. Monitoring their safety for consumer’s health is an urgent task of modern preventive medicine. Aim. Generalization of the results of a comprehensive sanitary and hygienic assessment of the safety for consumers the dietary supplement «Tyro Ultra», created to support the normal function of the thyroid gland. Materials and Мethods. Residual concentrations of pesticides were estimated by the methods of ultra-high-performance highspeed mass spectrometric liquid chromatography with electron spray ionization (Waters, USA) and gas chromatography; the content of heavy metals – by the atomic emission method (Shimadsu ICPE - 9820); content of radionuclides – by spectrometry; investigated microbiological indicators. Results. It has been established that the dietary supplement «Tyro Ultra» meets the requirements of Ukrainian legislation; its chemical and microbiological composition does not pose a threat to the health of consumers, provided that the method and dosage of the dietary supplement are in accordance with the manufacturer's recommendations. According to the review of scientific sources, the components of the «Tyro Ultra» formulation have the potential to normalize metabolism, optimize the chemical composition of the diet, and create optimal dietary conditions to support the normal functioning of the thyroid gland. Conclusions. Assessing the safety of traditional Ayurvedic formulations is an important and at the same time difficult task due to their multi-component composition. Further studies of products made on the basis of traditional recipes will contribute to the expansion of our imagination about means that have the potential of targeted influence on the level of adaptation capabilities of the human body in conditions of negative impact on the environment. Keywords: dietary supplements, sanitary and hygienic assessment, thyroid gland.

Some approaches and criteria for assessing the risk of developing occupational diseases

Introduction. The creation of safe working conditions allows not only to reduce the rates of occupational morbidity and occupational injuries among employees, but also to increase the efficiency and efficiency of work, which together reduce the financial losses of employers. Therefore, the improvement of methodological approaches to the assessment of occupational risks is an urgent task of modern preventive medicine. The study aims to substantiate the need to apply new approaches and criteria for determining the level of occupational risk based on the analysis of occupational morbidity in a group of people exposed to harmful industrial factors. Materials and methods. Researchers have carried out a retrospective analysis of occupational morbidity and an analysis of the working conditions of railway transport workers (798,126 people) operating in conditions of constant exposure to harmful production factors. Indicators of occupational morbidity have been recalculated for 10 thousand workers employed in workplaces with harmful and dangerous working conditions. The authors used the software and application package "SPSS 23" during the calculations. Results. The main occupational diseases of railway transport workers are: professional sensorineural hearing loss (PSHL) (60-75%), pneumoconiosis and dust bronchitis (4-20%), diseases of the peripheral nervous system and musculoskeletal system (6-9%), vibration disease (WD) (3-10%). The indicator of occupational morbidity per 10.000 of all employees of JSC "Russian Railways" for PNST, radiculopathy and vibration disease were 0.25, 0.014, 0.056, respectively. The new indicator of occupational morbidity, calculated for 10,000 workers working in harmful and dangerous working conditions with factors such as noise, vibration, and severity of labor, was: PSHL - 1.08, radiculopathy - 0.06, WD - 0.78. We have carried out the forecasting of the development of PSHL, which is based on data on the profession, the presence of harmful production factors, age-experience indicators and the degree of PSHL. Conclusion. The existing approach to the assessment of occupational morbidity, calculated for 10 thousand of all employees, is not objective, does not reflect real risk levels, understates official data on occupational morbidity, and creates difficulties for the development of effective management decisions. It is necessary to approve a new approach to the assessment of occupational morbidity, calculating it for 10 thousand workers directly exposed to harmful and dangerous factors. The developed prognostic model of the risk of developing PSHL, based only on information about the profession, work experience, and age of the employee, is not objective and does not give accurate predictions about the timing of the onset of occupational disease. To improve the prognostic model, it is necessary to include additional indicators based on clinical and laboratory studies, as provided by the methodology for the formation of risk groups (groups 1-5) for the development of occupational diseases.

Foot Reflexology: Recent Research Trends and Prospects

Foot reflexology is a non-invasive complementary therapy that is increasingly being accepted by modern people in recent years. To understand the research trends and prospects of foot reflexology in the past 31 years, this study used the Web of Science core collection as the data source and two visualization tools, COOC and VOSviewer, to analyze the literature related to the field of foot reflexology from 1991 to 2021. This study found that the number of articles published in the field of foot reflexology has been increasing year by year, and the top three journals with the most articles are Complementary Therapies in Clinical Practice, Therapies in Medicine, and the Journal of Alternative and Complementary Medicine. The top three most prolific authors are Wyatt, Sikorskii, and Victorson, and the core institutions in the field of foot reflexology are Michigan State University, Northwestern University, Tehran University of Medical Sciences, and the University of Exeter. Foot reflexology has been shown to have a moderating effect on anxiety, fatigue, and cancer, and is a topic of ongoing and future research. This study uses this bibliometric analysis of foot reflexology literature to provide an overview of prior knowledge and a reference direction for modern preventive medicine.

Application of the Prevention of Disease Concent in Traditional Chinese Medicine in Acupuncture Rehabilitation Treatment of Chronic Diseases： Take Vascular Dementia as an Example

The concept of rehabilitation prevention is one of the basic theories of rehabilitation medicine of traditional Chinese medicine (TCM), early rehabilitation intervention will help to prevent or reduce the loss of function or disability of patients. This is similar to the theory of preventive treatment of disease in TCM and three-level prevention in modern preventive medicine. Acupuncture and moxibustion has a long history and plays an important role in the preventive treatment of Alzheimer's disease (AD), vascular dementia (VD) and other senile diseases. Taking VD as an example, this paper discussed the rehabilitation treatment of acupuncture and moxibustion of VD and its possible mechanism, which explained that acupuncture and moxibustion therapy played a preventive and therapeutic role in the early stage of dementia, and embodied the TCM concent of "prevent before the disease arises and prevent disease from exacerbating". The early intervention of TCM rehabilitation technology can transform forward the focus of prevention and control of chronic diseases. To construct a new model of intelligent rehabilitation of TCM based on the theory of preventive treatment of disease, and develop a standardized acupuncture and moxibustion rehabilitation technology with the assistance of internet and information construction, which will help to improve the effectiveness, safety and patient compliance of TCM acupuncture and moxibustion rehabilitation services, and will contribute to advancing the healthy China.

Necessity and Strategy of Preventive Medicine Education in Higher Vocational Medical Specialty

With the continuous development of modern preventive medicine, the proportion of preventive medicine professionals required by the society is also increasing. This is why higher vocational colleges need to strengthen preventive medicine education and train preventive medicine professionals, which has become a necessary task of higher vocational colleges. Under the new situation of higher education, the traditional preventive medicine curriculum cannot meet the actual needs and needs to be reformed. Therefore, teachers of preventive medicine course in higher vocational colleges should strengthen their understanding of the current situation of the course and reform it in effective ways and strategies to make the preventive medicine teaching meet the implementation requirements.

Preventive medicine in Russia: The problem of public (dis)trust

Based on a range of empirical studies, the article discusses the contemporary challenges and contradictions for the development of preventive medicine in Russia amongst the enormous distrust of the population towards preventive medical measures. In the context of the COVID-19 pandemic, the discussion about preventive medical actions as a necessary measure for maintaining national security has assumed new importance. While the Russian government tries to reduce the epidemiological and economic risks by strengthening control and involving the population in preventive procedures, “coronavirus restrictions” have caused significant discontent among the population. The protest voices of “COVID dissidents” are heard loudly in public spaces, and the arguments of opponents of vaccination are widespread in Russian society. However, even before the pandemic, the wary attitude of the population towards vaccinations and preventive measures was already acutely problematic. In 2020-2021 a sociological study was conducted to identify a number of objective and subjective factors of public (dis)trust towards preventive medical measures, and, in general, the value attitude towards health and preventive care in Russian society. The analysis showed the sensitive points of the Russian’s attitude to preventive medicine and issues of health promotions, demonstrating the existing stereotypes and fears of people, as well as the problems of modern preventive medicine in general and vaccination. The authors conclude that the problem of institutional (dis)trust is key for the development of preventive medicine in Russia. Without voluntary and interested participation of the population in medical practices, the development of the modern concept of predictive, preventive, personalised and participative medicine will not be successful.

The importance of prebiotics in the regulation of metabolic syndrome disorders

The products of functional foods differ from other meals by their ability to improve health and well‑being or to reduce the risk of diseases and not only to provide the good nutrition. The composition of such products includes oligosaccharides of the fructan type such as inulin. Inulin is a soluble dietary fiber, consisting of a group of natural polysaccharides that are not digested in the intestine and instead fermented into short‑chain fatty acids associated with multiple metabolic processes, including glucose homeostasis and insulin resistance. Besides, inulin affects the lipid exchange regulation and improvement of lipid profile. Inulin is a mixture of linear fructose polymers or fructans with 2 — 60 units, each of them is connected by unique β (2‑1) bonds with a glucose unit. In contrary to typical carbohydrate, these β (2‑1) connections cannot be hydrolyzed by enzymes of saliva or pancreas, that’s why inulin has a reduced energetic value as well as dietary prebiotic effects.Functional food is an important component of the change in the lifestyle to control obesity and related risks for health. Obesity and dyslipidemia are important aspects of metabolic syndrome, associated with changes in the gut microbiome. The most important direction in the modern preventive and therapeutic medicine presents the use of prebiotics, that provide positive effects on the normal microflora and cause a whole cascade of secondary beneficial effects for humans (metabolic, anticarcinogenic, immunostimulating, antitoxic, etc.). Prebiotic Inulin promotes the restoration of intestinal microbiome by means of increasing production of intestinal epithelial cells and recovering interleukin‑22 expression.On the domestic market inulin presented as an Inulin‑NEO preparation, available in a form of tablets and sachet, which makes it easy to use.

Сomprehensive content of safety of vital activity

The discipline “Safety of vital activity” emergence as a mandatory subject in schools and universities is related to increased amount and the “quality” of risks generated by scientific and technological progress and appearance of environmental changes within the modern society the technosphere. The safety of vital activity initial foundations is initiated in the family and are subsequently formed and developed in the preschool institution. From the socialization perspective of the individual, the school years are classified as primary school age, adolescence, youth, that characterize socially constructed age periods. This indicates the necessity of creative approaches with including the training programs for safety of vital activity basics. In many cases the training programs and manuals on safety of vital activity programs contains a list of emergencies and the rules of conduct within the occurrence of it, in the absence of the causal analysis, of the medium and long-term consequences of their impact, which is the fundamental in understanding of the essence, predicting and preventing such situations. An alternative to resolving such contradictions can be the introduction of “Ecology” and “Valeology” as mandatory subjects, which appeared concurrently with the “Safety of vital activity”, and then disappeared from many educational programs. This range of educational programs represents the organic unity and internalinter connection and focusing increasingly on solving practical problems with concrete results in ensuring the safety of society. The Valeology is the branch of modern preventive medicine aimed to promoting healthy lifestyles. The achievement of Valeology is the separation between health and illness of an intermediate, “third state”, when a person is not sick yet, but is no longer healthy. The above characteristics of Ecology and Valeology, which makes visible the organic unity and internal relationship with the “Safety of vital activity”. The full pedagogical content of safety and life, and activities in modern conditions of societies existence can be considered as a single set.

POTENTIAL OF PREVENTIVE ROLE OF AYURVEDIC MANAGEMENT IN FLUE LIKE SYMPTOMS IN CHILDREN: A REVIEW

The advent of the novel corona disease Covid-19 has brought about a situation that needs urgent global attention. As no specific antiviral drugs are available in mainstream medicine for treating symptoms of Covid-19, prevention seems to be the best strategy. But unfortunately, currently no modern preventive medicine is available, too. Different theories regarding treatment of Covid -19 are budding up daily. In this scenario the world is hopefully looking at complementary and alternative medicine to come up with a solution. Though, the scientists all over the world, are trying hard for the development of antiviral drug and vaccine for Covid-19, emergence of the virulent strain, with least scientific studies and information, uncertainty of time required for development of Covid -19 vaccine and mass casualties have made the situation very grave. Ayurvedic herbal and herbo-mineral preparations have shown a wide range of bio-chemical activities and they can be effectively used as preventive measure in present times. Few of them are discussed here as an evidence based approach so that their potential can be used in this time of pandemic.

Can We Improve the Evaluation of Cardiovascular Risk in Obese Children? A Possible Study Protocol

Abstract The link between obesity and a wide range of cardiovascular disorders is well known.(1,2) In recent years, the prevalence of obesity has reached an alarming level.(3) Unfortunately, the situation is similar for the paediatric population – which may provide a perspective on the continuously growing global burden of this affliction.(4) Acting upon this issue is a fundamental direction in modern preventive medicine. A firm action starting in childhood may prove itself to be more beneficial the sooner it is implemented. Multiple anthropometric, clinical, laboratory and imaging parameters have been related to the presence of obesity and cardiovascular risk. This article represents a proposal for a possible protocol of a study aimed at paediatric obesity as a cardiovascular risk factor and aims to construct a model for a therapeutic intervention in these patients.

Практические аспекты оказания медицинской помощи при отказе от курения

Controlling the development of chronic non-communicable diseases is one of the main mass activities of modern preventive medicine. In this work, modern medicine focuses on the influence of modifiable risk factors. Among these risk factors for developing chronic non-communicable diseases, Smoking occupies a special place. Aim. To analyze the provision of medical care when quitting Smoking on the example of a city polyclinic. Matherials and methods. We have analyzed the provision of medical care for quitting Smoking in a city polyclinic. Results. Medical care for quitting Smoking in our country is provided in the conditions of outpatient care. This assistance consists of comprehensive patient support, including individual counseling and regular check-UPS to the doctor. Conclusions. The analysis of medical care for quitting Smoking has shown its effectiveness, which is confirmed by the clinical situation.

Practice and Exploration of Open Experimental Teaching in Preventive Medicine

<p>With the transformation of disease model and the development of related basic science, the research mode of preventive medicine is also changing. The traditional medical model mainly refers to the biomedical model. With the exploration of the medical field, the biomedical model has been transformed into the modern medical model, that is, the bio-psychology-social medical model. And the preventive medicine model has undergone significant changes along with the transformation of the entire medical model. Modern preventive medicine is an important means to protect human health. Due to people's social attributes, various social and psychological factors will affect the health of the population.Through people's new cognition and research on various factors affecting health in modern preventive medicine, modern preventive medicine has very obvious social benefits.This article mainly explains the practice and exploration of open experimental teaching of preventive medicine in China.</p>

SEASONAL MONITORING ELECTROMAGNETIC SITUATION IN THE RADIO-FREQUENCY RANGE OF MOBILE COMMUNICATION

Introduction. The study of the electromagnetic environment created by mobile communication terminals (MCT) is one of the important tasks of modern preventive medicine. In the study, the assessment of the electromagnetic environment created by MCT according to fluence values. Material and methods. The fluence level of MCT radiation was determined in the territory of the Crimea using a mobile monitoring system. The number of paired (seasonally) fluence measurement points accounted for 2102. At each point, the level of electromagnetic radiation (EMR) was determined sequentially from two identical MP (Samsung G3) in voice mode with the remote subscriber. Results. The average fluence value in Crimea for the year amounted to 1.45 ± 0.06 μW/cm2. In the winter (non-resort) season fluence accounted for 1.34 ± 0.05 µW/cm2, in the summer (resort) season -1.54 ± 0.05 µW/cm2. A comparative non-parametric analysis of the winter and summer fluence values in the resort regions revealed significant differences, whereas in non-resort regions there were no significant differences. Obtained as a result of monitoring of the electromagnetic situation, the data showed significant heterogeneity of fluence by administrative units within the Republic of Crimea from 0.92 ± 0.03 in the Belogorskiy to 2.11 ± 0.07 μW/cm2 in the Chernomorsky regions, which indicates the difference in mobile coverage areas in Crimea. Significant differences between the fluence values obtained in the winter and summer seasons for resort regions can be explained by the uneven workload of base stations due to the seasonal dynamics of the influx of tourists. Conclusion. As a result of the work done, an average annual fluence value of 1.45 ± 0.06 µW/cm2 was obtained, its considerable heterogeneity and reliable seasonal changes were revealed. Keywords: seasonal monitoring; cell phone; fluence.

THE PREVALENCE OF CARDIOVASCULAR DISEASE DUE TO ELECTROMAGNETIC LOADS GENERATED BY MOBILE COMMUNICATION

Introduction. Identification of the relationship between the prevalence of carfiovascular diseases and the electromagnetic environment generated by mobile communication terminals (MCT) is an current problem of modern preventive medicine. In the work an assessment of the electromagnetic situation generated by the MCT on value to the individual electromagnetic loading (IEL) is given. Material and methods. Using data measured in 2102 points the energy stream density (ESD), and the access interval (AI), determined by a crowdsourcing method, the individual electromagnetic exposition (IEE) by 1,850 reports on specification of calls in the Republic of Crimea. Using the obtained data of counting the individual electromagnetic loading (IEL). The medico-statistical analysis of the blood circulatory system diseases (BCSD) is carried out on the basis of these statistical forms of treatment. Statistical processing was carried out by the linear correlation analysis according to Pearson. Results. As a result of monitoring of the electromagnetic situation, the average values of the Crimea ESD accounted for 1.36±0.06(mW/cm2), АI: 8.82±0.28, and IEE: 56.94±2.77 min/day were obtained. The average IEL in Crimea was 112.41±9.15 ((µw/cm2)•min). Positive correlations between IEN and indices of morbidity rate of diseases of the circulatory system (DCS) (R=0.511; p=0.015), elevated blood pressure (IBP) (R=0.523; p=0.013), and coronary heart disease (CHD) (R=0.452; p=0.035)) were found. Conclusion. Significant correlations between IEL and DCS, IBP and CHD. Discovered a new correlation between the IEL and increased overall morbidity (IBP) (R=0.449; p=0.036)) allows evaluating the method of determining the IEL as a more “sensitive”.

ENDOTOXINEMIA, DYSREGULATION AND THE PRE-ILLNESS FORMATION

The study of the conditions of pre-illness and early stages of the disease, as well as their mechanisms, are of particular relevance for modern preventive medicine. It is known that dysregulation is the basis of many pathological processes, the leading link in the pathogenesis of which is endotoxinemia, the severity of which is largely determined by the state of detoxification liver function. The aim of the study was to elucidate the significance of the liver detoxification function and endotoxinemia in the occurrence of dysregulation and the pre-illness formation. In experiments on rats and rabbits it was is established that the direction and nature of changes in the processes of heat exchange, energy and plastic supply of the organism, their hormonal and humoral regulation under the action of E. сoli endotoxin (LPS) depend on the severity of endotoxinemia, the state of detoxification liver function. It is shown that in conditions of functional liver failure, the action of LPS in the body in trace concentrations is accompanied by an increase, and with severe endotoxinemia, a decrease in the activity of the processes of energy and plastic supply of the organism, detoxification. It was found that the ambiguous direction and nature of the changes in the processes of heat exchange, energy and plastic supply of the organism, their neurotransmitter, hormonal and humoral regulation under conditions of endotoxinemia depend on its severity and are largely due to a decrease in the level of arginine in blood plasma and cerebrospinal fluid. In experiments on rats it was revealed that the central action of 1-noradrenaline (10 μg) under the conditions of preliminary introduction of L-arginine hydrochloric acid (100 μg) into the brain ventricles (for 15 min) exerts a more pronounced and prolonged decrease in body temperature in comparison with control, while the duration and severity of the hypothermic effect from the introduction of acetylcholine into the brain ventricles at a dose of 2.5 μg with eserine (5 μg) decreased. It was found that in conditions of bacterial endotoxinemia, accompanied by an increase in body temperature and a decrease in the level of arginine in blood plasma and cerebrospinal fluid in rabbits, intensive utilization of 14C-arginine hydrochloric acid from tissues of the hypothalamus takes place. Endotoxinemia is a key link in the pathogenesis of disregulatory pathology and a universal factor in the development of such a condition as pre-illness.

The Emergency of Nutraceutical Compounds in the Preventive Medicine Scenario. Potential for Treatment of Alzheimer's Disease and Other Chronic Disorders

Evidence-based Nutraceutical Compounds (EBNC), containing bioactive principles of demonstrated efficacy and health security are opening solutions for a modern preventive medicine, and as potential solutions for many chronic diseases of the human beings. EBNC contain bioactive components of the human diet that can be used for the prevention or treatment of a disease. They are obtained through rigorous processes of extraction from natural resources and Good Manufacturing Practices (GMP) regulations, and exhibit sound preclinical studies published in high impact medical journals, and double-blind placebo-controlled clinical trials. Are these compounds significantly more effective than alternative medicines? EBNC rely on some of the major advances in molecular genetics, epitranscriptomics, molecular biology and modern pharmacology. They are certainly opening a solid pathway in benefit of human health and the welfare of mankind.

Stratified prevention: opportunities and limitations. Report on the 1st interdisciplinary cardiovascular workshop in Augsburg

Sufficient exercise and sleep, a balanced diet, moderate alcohol consumption and a good approach to handle stress have been known as lifestyles that protect health and longevity since the Middle Age. This traditional prevention quintet, turned into a sextet by smoking cessation, has been the basis of the “preventive personality” that formed in the twentieth century. Recent analyses of big data sets including genomic and physiological measurements have unleashed novel opportunities to estimate individual health risks with unprecedented accuracy, allowing to target preventive interventions to persons at high risk and at the same time to spare those in whom preventive measures may not be needed or even be harmful. To fully grasp these opportunities for modern preventive medicine, the established healthy life styles require supplementation by stratified prevention. The opportunities of these developments for life and health contrast with justified concerns: A “surveillance society”, able to predict individual behaviour based on big data, threatens individual freedom and jeopardises equality. Social insurance law and the new German Disease Prevention Act (Präventionsgesetz) rightly stress the need for research to underpin stratified prevention which is accessible to all, ethical, effective, and evidence based. An ethical and acceptable development of stratified prevention needs to start with autonomous individuals who control and understand all information pertaining to their health. This creates a mandate for lifelong health education, enabled in an individualised form by digital technology. Stratified prevention furthermore requires the evidence-based development of a new taxonomy of cardiovascular diseases that reflects disease mechanisms. Such interdisciplinary research needs broad support from society and a better use of biosamples and data sets within an updated research governance framework.

HEALTH STATE OF MEDICAL STUDENTS AND ITS DETERMINANTS

The preservation and promotion of health in youth is one of the most urgent and important health and social problems at the present stage. In the Russian Federation, sanitary supervision of institutions of higher professional education is carried out both for public facilities and for universities, where there are no specially developed sanitary rules and regulations. From the positions of modern preventive medicine, it is impossible to carry out reasonable health-improving measures in educational institutions of a medical profile without hygienic assessment of microclimate conditions, chemical composition of indoor air, levels of illumination, noise and electromagnetic fields. The article is devoted to the assessment of the health state of medical students in the conditions of various social and hygienic, ecological and biological factors. The hygienic characteristic of the levels of illumination and microclimate of the classrooms is given. The protection of students' health from the negative impact of electromagnetic fields from computers is also an important medical, technical and social task. Significant emphasis in the article is given to a problem of spreading bad habits, including smoking and drinking alcohol. Hygienic features of education in medical schools and prevention issues were also presented. There is a need to promote knowledge of hygiene and healthy lifestyle among students in the form of lectures, conversations and visual propaganda. Students in the form of lectures and conversations, visual propaganda.