Modern Instruments Research Articles

Automatic food and beverage authentication and adulteration detection by classification hybrid fusion

AbstractA rising problem in the food industry is identifying the origin and/or purity of food products, and classification is often used for the identification. The process involves determining whether a food sample is similar to a collection of samples characterizing a known food product (is the food product a class member?). However, classification requires the analyst to face a myriad of complex decisions. With modern instrumentation, classification based on conventional data fusion processes increases the assortment of decisions. Typically, testing food products without data fusion involves (1) selection of an instrument or measuring device, (2) determining suitable measurement variables, for example, sensors or wavelengths for spectral data, (3) data preprocessing optimization, and (4) selection of a classification method followed by identifying the best tuning parameter setup for that classifier. If data fusion is desired, optimization of combined variations of (1)–(4) is required. This paper overviews a recent approach that simplifies data fusion decisions for food authentication and adulteration classification purposes. This unique self‐optimized fusion method avoids the confounding decisions by simultaneously evaluating any number of permutations of (1)–(3) in combination with a collection of non‐optimized classifiers based on respective tuning parameter windows for (4). Self‐optimization is obtained by using the sum of ranking differences (SRD) to form the final fused class membership decision for each new food test sample where the SRD was automatically optimized using a receiver operator characteristic (ROC) curve. The simple automatic SRD hybrid fusion/ROC curve process removes the myriad of subjective decisions imposed on the analyst and increases food classification reliability. Results are demonstrated with three datasets.

Multiblock methods in Analytical Chemistry

Chemometrics, and multivariate data analysis in particular, has become a significant component of Analytical Chemistry. This is because of the need to have mathematical methods capable of extracting the pertinent information from the ever-increasing amounts of data generated by modern instruments. Usually, these multivariate data analysis methods are concerned with the exploratory analysis of a single data matrix, as in PCA, or with relating one explanatory matrix to another descriptive matrix, as in regression methods such as PCR and PLS, or discriminant methods, such as FDA and PLS-DA.

Canine Olfaction: Physiology, Behavior, and Possibilities for Practical Applications

Simple SummaryDogs have an extraordinary olfactory capability, which far exceeds that of humans. Dogs’ sense of smell seems to be the main sense, allowing them to not only gather both current and historical information about their surrounding environment, but also to find the source of the smell, which is crucial for locating food, danger, or partners for reproduction. Dogs can be trained by humans to use their olfactory abilities in a variety of fields, with a detection limit often much lower than that of sophisticated laboratory instruments. The specific anatomical and physiological features of dog olfaction allow humans to achieve outstanding results in the detection of drugs, explosives, and different illnesses, such as cancer, diabetes, or infectious disease. This article provides an overview of the anatomical features and physiological mechanisms involved in the process of odor detection and identification, as well as behavioral aspects of canine olfaction and its use in the service of humans in many fields.Olfaction in dogs is crucial for gathering important information about the environment, recognizing individuals, making decisions, and learning. It is far more specialized and sensitive than humans’ sense of smell. Using the strength of dogs’ sense of smell, humans work with dogs for the recognition of different odors, with a precision far exceeding the analytical capabilities of most modern instruments. Due to their extremely sensitive sense of smell, dogs could be used as modern, super-sensitive mobile area scanners, detecting specific chemical signals in real time in various environments outside the laboratory, and then tracking the odor of dynamic targets to their source, also in crowded places. Recent studies show that dogs can detect not only specific scents of drugs or explosives, but also changes in emotions as well as in human cell metabolism during various illnesses, including COVID-19 infection. Here, we provide an overview of canine olfaction, discussing aspects connected with anatomy, physiology, behavioral aspects of sniffing, and factors influencing the olfactory abilities of the domestic dog (Canis familiaris).

Numerical Simulation on the Dissociation, Formation, and Recovery of Gas Hydrates on Microscale Approach.

Investigations into the structures of gas hydrates, the mechanisms of formation, and dissociation with modern instruments on the experimental aspects, including Raman, X-ray, XRD, X-CT, MRI, and pore networks, and numerical analyses, including CFD, LBM, and MD, were carried out. The gas hydrate characteristics for dissociation and formation are multi-phase and multi-component complexes. Therefore, it was important to carry out a comprehensive investigation to improve the concept of mechanisms involved in microscale porous media, emphasizing micro-modeling experiments, 3D imaging, and pore network modeling. This article reviewed the studies, carried out to date, regarding conditions surrounding hydrate dissociation, hydrate formation, and hydrate recovery, especially at the pore-scale phase in numerical simulations. The purpose of visualizing pores in microscale sediments is to obtain a robust analysis to apply the gas hydrate exploitation technique. The observed parameters, including temperature, pressure, concentration, porosity, saturation rate, and permeability, etc., present an interrelationship, to achieve an accurate production process method and recovery of gas hydrates.

Meniscal Injuries: Mechanism and Classification.

Meniscal tears may be managed through conservative physical therapy and nonsteroidal anti-inflammatory medications or operative intervention. Meniscal repair is superior to partial meniscectomy with better functional outcomes and less severe degenerative changes over time. Surgical advances in operative techniques, modern instrumentation and biological enhancements collectively improve healing rates of meniscal repair. However, failed repair is not without consequences and can negative impact patient outcomes. Therefore, it is imperative for surgeons to have a thorough understanding of the vascular zones and biomechanical classifications of meniscal tears in order to best determine the most appropriate treatment.

Research on the Application of Computer Technology in Data Processing of University Chemical Experiment

University chemistry is a subject based on experimental verification, which is inseparable from instruments and data analysis. However, with the increasing complexity of university chemistry experiments, we need to use modern instruments for analysis, which can record experimental data more accurately. However, there are clear requirements for the processing of experimental data. With the different purposes of the experiment, we need different graphics and data analysis, which needs the help of computer technology. Through the computer technology, we can realize the automation of chemical experiment instrument operation, which can also automatically collect and transmit test data. Therefore, computer technology not only promotes the development of modern chemical instrument technology, but also improves the processing of university chemical experiment data. First of all, this paper analyzes the main application software technology. Then, this paper puts forward some examples for MATLAB and origin respectively.

Electronic cigarettes: Modern instruments for toxic lung delivery and posing risk for the development of chronic disease.

Following the emergence of electronic cigarette, or vaping product use associated lung injury (EVALI) in 2019 in the US, regulation of e-cigarettes has become globally tighter and the collective evidence of the detrimental effects of vaping has grown. The danger of cellular distress and altered homeostasis is heavily associated with the modifiable nature of electronic cigarette devices. An array of harmful chemicals and elevated concentrations of metals have been detected in e-cigarette aerosols which have been linked to various pathogeneses. Vaping is linked to increased inflammation, altered lipid homeostasis and mitochondrial dysfunction whilst also increasing microbial susceptibility whilst the long-term damage is yet to be observed. The scientific evidence is mounting and highlighting that, along with traditional tobacco cigarette smoking, electronic cigarette vaping is not a safe practice.

A Combined Non-Destructive and Micro-Destructive Approach to Solving the Forensic Problems in the Field of Cultural Heritage: Two Case Studies

The present paper discusses the importance of non-destructive and micro-destructive technology in forensic investigations in the field of cultural heritage. Recent technological developments and the wide availability of modern analytical instrumentation are creating new possibilities for performing scientific measurements and acquiring data directly on-site—thereby limiting, where possible, sampling activity—as well as learning about the technologies and materials that were employed in the past to create cultural assets. Information on periods, chemical composition, manufacturing techniques, etc., can be gathered more easily. Overall, the benefits of on-site forensic investigations are multiple, including the potential to increase substantially the speed and efficacy of the criminal justice system. However, such benefits are only realized when data quality is guaranteed and findings can be used as forensic evidence in court. The present paper shows data from the non-destructive and micro-destructive analysis of different artworks and objects provided by the Cosenza Carabinieri Unit for the Protection of Cultural Heritage and Anti-Counterfeiting (Calabria, Italy). In particular, two oil paintings on canvas depicting cherubs (Italian: putti), recovered as fragments of larger religious artworks, and two bronze belt and helmet fragments were investigated. In the first case, the research aimed to define the original pictorial layer, identify any reconstruction pictorial areas or pictorial retouching, assess the state of conservation, reconstruct the previous conservation treatments, and provide indications about the chronology of the artworks. In the second case, analysis was performed both to define the bronze chemical composition and the origin of the soil (earth) found within the objects during their recovery. For these purposes, the analytical approach involved the use of non-destructive and micro-destructive analysis as follows: infrared reflectography (IRR), ultraviolet-induced visible fluorescence (UV), X-ray fluorescence analysis (XRF), digital optical microscopy (DOM), scanning electron microscopy equipped with EDX microanalysis (SEM-EDX), and Fourier transform infrared spectroscopy (FT-IR). The results made it possible to collect valuable diagnostic information and answer questions posed by the institutions for the resolution of various doubts about forensic science and cases concerning the seizure, recovery, or return of archaeological or historical-artistic objects of cultural interest.

Nonlinear Whole Seismology, Topological Seismology, Magnitude-Period Formula of Earthquakes and Their Predictions

First, we propose the nonlinear whole seismology and its three basic laws. Next, based on the nonlinear equations of fluid dynamics in Earth’s crust, we obtain a chaos equation, in which chaos corresponds to the earthquake, and shows complexity on seismology. But, combining the Carlson-Langer model and the Gutenberg-Richter relation, a simplified nonlinear solution and corresponding magnitude-period formula of earthquakes may be derived approximately. Further, we research the topological seismology. From these theories some predictions can be calculated quantitatively and are already tested. Combining the Lorenz nonlinear model, we may discuss the earthquake migration to and fro. Finally, if various modern scientific instruments, different scientific theories and some paranormal ways for earthquake are combined each other, the accuracy of multilevel prediction will be increased.

A holistic approach to the optimization of neutron beam transport at the LANSCE facility

An advanced neutron beam collimation system has been developed as part of an effort to optimize neutron beam transport at the Weapons Neutron Research (WNR) Facility [1], located within the Los Alamos Neutron Science Center (LANSCE). The goal of this work was to develop and demonstrate techniques to tailor neutron delivery in order to provide maximum available flux on sample with a specific beam profile, while simultaneously reducing unwanted background. A holistic approach was taken, upgrading the facility spallation target, facility metrology infrastructure, and flight path shutter insert to support the implementation of this advanced collimation system. Modern instruments and software were employed to conduct facility surveys, characterization of as-built geometry of critical components, 3D ray tracing and neutron transport calculations. Beam images and flux measurements were acquired after installation to evaluate the performance of the collimation system and to demonstrate consistent agreement with MCNP simulations which showed an 87% increase of flux on sample while providing suppression of background neutron impingement on the sample frame by 103.

ORGANIZATIONAL AND LEGAL MECHANISMS TO COUNTERACTION ILLEGAL MIGRATION BY SEA

Globalization, imbalance in development of states, economic and political crises, search for a better life and military action often force people to leave their usual places of residence. A significant component of migration processes is illegal migration, which is especially dangerous when carried out by sea. The fragmentary nature of modern legal research in this area has led to the choice of the article to describe modern organizational and legal mechanisms to counteraction illegal migration by sea in the ongoing pandemic and develop proposals for their improvement. Based on the application of research methodology, which combines a number of general scientific (dialectical, historical) and special legal (formal legal, scientific forecasting) methods of scientific research, the article clarifies the dynamics of migration processes in the modern world. With the Mediterranean region serving as the example, their illegal component is characterized. Political, legal and organizational directions of cooperation of states in the counteraction against illegal migration are singled out, with the description of their relationship provided. It is noted that the availability of modern legal instruments has not helped to cope with the increasing number of migration flows and the consequences of illegal migration in the mid‑2010s in the EU. The impact of border restrictions due to the spread of the COVID‑19 pandemic was not significant. The decline in illegal migration in the Mediterranean region is due to other organizational measures. It is concluded that it is currently necessary to ensure high-quality implementation of international law, IMO and other international institutions’ recommendations. There is the need to develop and improve bylaws directly related to counteraction illegal migration at sea. The responsibility of states, their vessels and rescue services and migrants on board vessels that do not meet maritime safety requirements should also be addressed.

Operative Treatment of Severe Cervical Spine Injuries Sustained in Youth Sports: Experience from a Pediatric Level 1 Trauma Center over a 16-Year Period

Background:Sports-related cervical spine injuries (CSI) are devastating traumas with the potential for permanent disability. There is a paucity of literature on operative CSI sustained in youth athletes.Hypothesis/Purpose:The aims of this study aims were to review injury characteristics, surgical treatment, and outcomes of severe pediatric CSI encountered in youth sports.Methods:We reviewed children less than 18 years old with operative sports-related CSI at a pediatric Level 1 pediatric trauma center between 2004−2019. All cases underwent modern cervical spine instrumentation and fusion. SCI were stratified according to the American Spinal Injury Association Impairment Scale (ASIA). Clinical, radiographic, and surgical characteristics were compared between groups of patients with and without spinal cord injury (SCI).Results:Three thousand two hundred and thirty-one children (mean, 11.3y±4.6y) were evaluated for CSI at our institution during the 16-year period. The majority of traumas resulted from sports/recreational activities and were seen in 1365 cases (42.3%). Of these, 171/1365 patients (12.5%) were admitted and 29/1365 patients (2.1%) required surgical intervention (mean age, 14.5y±2.88y; range, 6.4y–17.8y). Sports included: eight football (28%), seven wrestling (24%), five gymnastics (17%), four diving (14%), two trampoline (7%), one hockey (3%), one snowboarding (3%), and one biking injury (3%). Mechanisms were 19 hyperflexion (65%), eight axial loading (28%), and two hyperextension injuries (7%). The majority of operative CSI were fractures (79%) and/or subaxial defects (72%). Seven patients (30%) sustained SCI and three patients (10%) spinal cord contusion or myelomalacia without neurologic deficits. The risk of SCI increased with age (15.8y vs. 14.4y; p=0.03) and axial loading mechanism (71% vs. 14%; p=0.003).Postoperatively, two SCI patients (29%) improved 1 ASIA Grade and one (14%) improved 2 ASIA Grades. Increased complications developed in SCI than patients without SCI (mean, 2.0 vs 0.1 complications; p=0.02). Clinical and radiographic fusion occurred in 24/26 patients (92%) with adequate follow-up (median, 32 months). Ten patients returned to their previous activity and nine to sports with a lower level of activity.Conclusion:The overall incidence of sports-related operative CSI is low. Age- and gender discrepancies exist, with male adolescent athletes most commonly requiring surgery. Hyperflexion injuries had a good prognosis; however, older males with axial loading CSI sustained in contact sports were at greatest risk of SCI, complications, and permanent disability.Figure 1.1:Etiology of all cervical spine injuries between 2004-2019

Materials Engineering of Violin Soundboards by Stradivari and Guarneri

AbstractWe investigated the material properties of Cremonese soundboards using a wide range of spectroscopic, microscopic, and chemical techniques. We found similar types of spruce in Cremonese soundboards as in modern instruments, but Cremonese spruces exhibit unnatural elemental compositions and oxidation patterns that suggest artificial manipulation. Combining analytical data and historical information, we may deduce the minerals being added and their potential functions—borax and metal sulfates for fungal suppression, table salt for moisture control, alum for molecular crosslinking, and potash or quicklime for alkaline treatment. The overall purpose may have been wood preservation or acoustic tuning. Hemicellulose fragmentation and altered cellulose nanostructures are observed in heavily treated Stradivari specimens, which show diminished second‐harmonic generation signals. Guarneri's practice of crosslinking wood fibers via aluminum coordination may also affect mechanical and acoustic properties. Our data suggest that old masters undertook materials engineering experiments to produce soundboards with unique properties.

An early experience of lumbopelvic fixation techniques at Alexandria University

BackgroundThe aim of lumbopelvic fixation is to obtain a solid fusion across the lumbosacral junction. There are many indications for lumbopelvic fixation, namely, spinal deformity in cases requiring long segment fusion, pelvic obliquity, pseudarthrosis at the lumbosacral junction, infection or osteolytic tumors, and pathologic fractures. The classical iliac screws should be contained within the iliac bone but have some disadvantages: excessive soft tissue dissection needed for accurate insertion, screw prominence with patient discomfort, and usually, a side connector is needed to connect the iliac screws to the rest of the construct. Lumbopelvic fixation by insertion of S2 alar-iliac (S2AI) screws was recently described to overcome these disadvantages. In this study, the authors present the initial results for the evaluation of lumbopelvic fixation through the insertion of S2AI screws in 19 consecutive patients operated in the neurosurgery department at Alexandria University.ObjectiveThe aim of the study was to evaluate the efficacy and complications of lumbopelvic fixation through the use of S2 alar-iliac screws.MethodsThe authors conducted a retrospective cohort study of data collected from the database of patients who underwent lumbopelvic fixation through the insertion of S2AI screws from 2016 to 2019 at a single institution.ResultsThere were 19 patients indicated for lumbopelvic fixation, operated by modern instrumentation systems using lumbar pedicle screws and S2 alar-iliac screws. There were 14 females and 5 males. The mean age at the time of the operation was 38.6 ± 19.4 years with a range from 11 to 65 years. There was a total of 37 S2AI screws, screw diameter was 7mm in all cases regardless of age, and the length of the screws ranged from 50 mm in a young female patient (11 years) to 90 mm in an old male patient (60 years). Two screws were inserted per patient except in one case with congenital scoliosis due to the bad bone quality and the multiple iatrogenic wrong paths. Postoperative VAS score for back pain was greatly improved in all patients after the first 6 months of follow-up from 8 ± 1.5 to 3.5 ± 1.2 (paired t-test = 11.182, P<0.001). All patients had a good spinal range of motion to maintain normal daily activities without any significant restrictions after the first 3 months of follow-up. Immediate postoperative radiological follow-up had revealed 2 cases of posterior pelvic breaches and one case with anterior pelvic breach but without clinical manifestations with no need for revision. Two cases of unilateral screw breakout were observed after the first 6 months of follow-up. Removal of screws after the first 6 months was done in one patient with spondylodiscitis due to the unresolved infection and screw pullout.ConclusionThe insertion of S2AI screws is an effective technique for lumbopelvic fixation with a relatively low rate of complications. Pelvic breaches are the commonest complications encountered during the insertion of S2AI screws, although no significant clinical morbidities were reported.

FEATURES OF THE CONTENT OF CHEMICAL ELEMENTS IN THE CONIFEROUS LARCH GMELINA IN THE AR-EA OF THE UDOKAN COPPER DEPOSIT

The article presents materials for the study of the content of chemical elements in the coniferous larch Gmelina (Larix gmelinii (Rupr.) Rupr.) family Pinaceae (syn.: Larix dahurica Turcz. ex Trautv., Larix amurensis Beissn.), growing in the high-altitude region of the North of the TRANS-Baikal territory, near the Udokan copper Deposit. The purpose of the research is to assess the concentration of a number of chemical elements in high-altitude and permafrost soils, while preparing the territory of the copper Deposit for exploitation. Selection of larch plant samples was carried out in the types of larch forests widely distributed in the research area, in June 2011. The analysis of pine needles samples was performed according to approved methods using modern instruments and equipment in the laboratory of Institute of Natural Resources, Ecology and Cryology SB RAS. It was found that in General L. Gmelin needles have a low concentration of chemical elements, which are arranged in the following sequence: Mg&gt; Sr&gt; Al&gt; Ba&gt; Fe &gt; Ti&gt; Ni&gt; Cu&gt; Mn&gt; Hg&gt; Zn&gt; V&gt; Ag&gt; Cr&gt; Pb&gt; Cd&gt; Sb&gt; Co&gt; Se&gt; As. At the same time, mercury is the only element whose concentration in larch conifers is much higher, 3.8 times, than that of land plants. The article presents a correlation table of the interaction of chemical elements. The table shows that titanium, aluminum, zinc, and silver have a greater effect on the content of chemical elements in conifers. The results presented in the article were obtained in the studied area for the first time. It is important to use the results of this work to monitor environmental pollution, to take into account when using larch to obtain medicinal substances, and to increase the productivity of forest plantations. Further research in this area may be related to other areas of distribution of larch forests, geochemical assessment of the region.

The Torsional Quartz-Crystal Viscometer

A complete theoretical analysis of the fluid and solid dynamics of the torsional quartz crystal viscometer is presented which for the first time, establishes a firm theoretical basis for two working equations whereby the viscosity of a fluid may be determined from measurements of the resonant frequency of the crystal and the width of the resonance when immersed in the fluid. Modern instrumentation means that it is possible to achieve higher resolution in the measurement of these two quantities than hitherto and the new theory opens the way to securing a concomitant accuracy in the determination of viscosity.

Modern assessment of bakery properties of Russian wheat

The paper presents an analysis of the quality of soft wheat grown in different soil and climatic conditions of the Russian Federation and having a wide range of quality indicators (the amount of gluten - from 15.3 to 29.4%, the quality of gluten - from 29 to 84 units. IIR, falling number - from 134 to 475 sec). Revealed significant differences in the quality of modern Russian wheat from the wheat of the late XX century. The interrelationships of indicators of quality of grain, flour obtained from it, rheological properties of dough with indicators of quality of bread on a modern instrument base using an alveograph, valorigraph and mixolab have been established. The study of the rheological properties of the dough on the mixolab was carried out in the classical "Chopin Wheat +" mode. According to the profiler parameters (radial diagram), it was found that the analyze grain was characterized by increased rates of starch retrogradation, which characterizes the carbohydrate-amylase complex of flour, a high water absorption index, and increased amylolytic activity; low viscosity and gluten +. To differentiate the strength of wheat, a test laboratory baking of bread was carried out using two methods - the remix method and the reduced-remix method, which showed that the most stable relationships were revealed when baking bread with the remix method. When baking with the abbreviated method, higher indicators of bread quality were obtained, but there are fewer stable relationships, moreover, both for wheat containing less than 25% gluten and more than 25%.

"Academization" of the saxophone: genesis, main milestones and current trends

The leading research topic in this article is the analysis of the specifics of the development of saxophone art in a symphony orchestra. The chosen problem requires the study of this direction from the perspective of a broader socio-historical context, within which it is possible to identify special signs of musical culture, both in the general context and in individual genres. In this vein, the study of saxophone music in a symphony orchestra allows us to outline, firstly, the origins of the origin of interest and the introduction of a special instrument into the cultural panorama, secondly, to trace the ways and impulses of its spread, and thirdly, to find out the problems of the saxophone as part of a symphony orchestra. In order to fully understand its special place in the cultural continuum of a certain place and epoch, music for the saxophone should be considered not just as a specific artifact that has been embodied in creativity, performance, education, but as a multi-level and three-dimensional concept in the musical art of the XIX-XXI centuries. The disclosure of the role of the saxophone as part of a symphony orchestra in the article is not just carried out through the prism of the representation of a certain number of facts, names, events, and can be traced as the correspondence of the development of the instrument to those historical, political, socio-economic and, above all, cultural and artistic processes that have formed a kind of creative reinterpretation of one of the most popular modern instruments. The purpose of the study is to substantiate the genesis, development trends and the current state of saxophone art in general, as well as, in particular, in the composition of a symphony orchestra. In the study, the author focuses on iconic performers and teachers, whose personal achievements in the field of concert, research and musical and social activities had a significant impact on the formation of the saxophone as part of a symphony orchestra.

Pediatric Reference Intervals for Critical Point-of-Care Whole Blood Assays in the CALIPER Cohort of Healthy Children and Adolescents.

Point-of-care testing (POCT) is being increasingly adopted to support clinical care. Data for critical care parameters in healthy children on POCT instruments are lacking. We established comprehensive reference standards for several whole blood parameters on the Radiometer ABL90 FLEX PLUS blood gas analyzer in the Canadian Laboratory Initiative on Paediatric Reference Intervals (CALIPER) cohort. Approximately 300 healthy children and adolescents (age range, birth to <19 years; sex, boys and girls) were recruited with informed consent. Venous whole blood was collected (using heparinized syringes) and rapidly analyzed at the point of collection for pH, Pco2, Po2, carboxyhemoglobin, methemoglobin, lactate, and electrolytes on the ABL90 FLEX PLUS instrument. Reference intervals were established according to Clinical and Laboratory Standards Institute guidelines. Of the parameters assessed, 6 required age partitioning; none required sex partitioning. Reference value distributions were consistent across the pediatric age range, demonstrating higher variation in the early neonatal period. This study established reference standards for 10 critical care analytes in the CALIPER cohort for the first time. These data contribute to our understanding of normative pediatric values for venous electrolytes, metabolites, and blood gases on a modern POCT instrument, facilitating test interpretation in clinical settings that use these assays.

RETRACTED: Government regulation of the Internet as instrument of digital protectionism in case of developing countries

The research is devoted to the study of digital protectionism technologies, in particular, Internet censorship as a non-tariff barrier to digital trade and the determination of the strategic motives of states to use them. The reports ‘Freedom on the Net’ and ‘The network readiness index 2020’ acted as a basic data source for the study of modern instruments of government regulation of interactions in the digital environment. Internet censorship technologies have been considered in six countries with varying levels of Internet freedom: Russia, Belarus, Kazakhstan, Georgia, Armenia and Estonia. The key instruments of digital protectionism as a non-tariff barrier of the digital economy have been identified, such as: localisation requirements; restrictions on cross-border data flow; system of national protection of intellectual property rights; discriminatory, unique standards or burdensome testing; filtering or blocking; restrictions on electronic payment systems or the use of encryption; cybersecurity threats and forced technology transfer. Internet censorship technologies have been demonstrated and their influence on the strategic development of trade relations between economies in cyberspace has been determined. The scientific value of the article lies in substantiating the understanding of Internet censorship as a natural tool for regulating the development of a digital society and international trade relations. Each state at one time goes through a technological stage of development, which leads to the emergence of different levels of digital isolation and integration; and Internet censorship is a natural element in the system of building a national platform economy and consolidating the country’s internal technological and innovative advantages in digital realities.