Exercise Research Articles

No Sex Differences in Perceptual Responses to High-Intensity Interval Training or Sprint Interval Training.

Coe, LN and Astorino, TA. No sex differences in perceptual responses to high-intensity interval training or sprint interval training. J Strength Cond Res 36(6): 1025-1032, 2024-High-intensity interval training (HIIT) elicits similar and, in some cases, superior benefits vs. moderate-intensity continuous training (MICT). However, HIIT is typically more aversive than MICT because of the higher intensity and in turn, greater blood lactate accumulation (BLa). This study explored potential sex differences in perceptual responses to acute HIIT and sprint interval training. Fifteen men (age and V̇O2max = 29 ± 8 years and 39 ± 3 ml·kg-1·min-1) and 13 women (age and V̇O2max = 22 ± 2 years and 38 ± 5 ml·kg-1·min-1) who are healthy and recreationally active initially underwent testing of maximal oxygen uptake (V̇O2max) on a cycle ergometer. In randomized order on 3 separate occasions, they performed the 10 × 1-minute protocol at 85% of peak power output, 4 × 4-minute protocol at 85-95% maximal heart rate (%HRmax), or reduced exertion high intensity interval training consisting of 2 "all-out" 20-second sprints at a load equal to 5% body mass. Before and throughout each protocol, rating of perceived exertion (rating of perceived exertion [RPE] 6-20 scale), affective valence (+5 to -5 of the Feeling Scale), and BLa were assessed. Five minutes postexercise, enjoyment was measured using the Physical Activity Enjoyment scale survey. Results showed no difference in RPE (p = 0.17), affective valence (0.27), or enjoyment (p = 0.52) between men and women. Blood lactate accumulation increased in response to all protocols (p < 0.001), and men showed higher BLa than women (p = 0.03). Previous research suggests that interval exercise protocols are not interchangeable between men and women, yet our data reveal that men and women having similar V̇O2max exhibit no differences in perceptual responses to interval exercise.

A mixed-method analysis of the contribution of informal sport to public health in Australia.

Informal sport is a growth area of sport participation but there has been limited examination of how informal and unstructured forms of participation may contribute to health outcomes that are important for public health. This article aims to address the current lack of data examining the health outcomes associated with informal sport participation and consider the potential role of informal sport within efforts to promote healthier communities through sport. The article seeks to broaden understanding of how informal sport participation can contribute to health outcomes, particularly with regard to increasing physical activity and enhancing mental health and social connection. The article discusses the findings of an Australian mixed-method study that draws on observation, survey, interview and focus group data to examine the prospective health and social benefits of informal sport participation for adults. The findings demonstrate that informal sport participation can contribute to physical and mental health outcomes and facilitate social connection. Analysis of the observation data enabled an examination of the economic value of informal sport in relation to the health benefits it affords. The study provides valuable evidence of the value of informal sport for enhancing community health and broadens understanding of how sport can be utilized as a health promotion resource. The article concludes by suggesting that through leveraging existing infrastructure and the self-organizing aspects of informal sport, local government and health stakeholders can harness its potential to improve public health outcomes and address health inequities.

Associations between regional adipose tissue distribution and skeletal muscle bioenergetics in older men and women.

The aim of this study was to examine associations of ectopic adipose tissue (AT) with skeletal muscle (SM) mitochondrial bioenergetics in older adults. Cross-sectional data from 829 adults ≥70 years of age were used. Abdominal, subcutaneous, and visceral AT and thigh muscle fat infiltration (MFI) were quantified by magnetic resonance imaging. SM mitochondrial energetics were characterized in vivo (31P-magnetic resonance spectroscopy; ATPmax) and ex vivo (high-resolution respirometry maximal oxidative phosphorylation [OXPHOS]). ActivPal was used to measure physical activity ([PA]; step count). Linear regression adjusted for covariates was applied, with sequential adjustment for BMI and PA. Independent of BMI, total abdominal AT (standardized [Std.] β = -0.21; R2 = 0.09) and visceral AT (Std. β = -0.16; R2 = 0.09) were associated with ATPmax (p < 0.01; n = 770) but not following adjustment for PA (p ≥ 0.05; n = 658). Visceral AT (Std. β = -0.16; R2 = 0.25) and thigh MFI (Std. β = -0.11; R2 = 0.24) were associated with carbohydrate-supported maximal OXPHOS independent of BMI and PA (p < 0.05; n = 609). Total abdominal AT (Std. β = -0.19; R2 = 0.24) and visceral AT (Std. β = -0.17; R2 = 0.24) were associated with fatty acid-supported maximal OXPHOS independent of BMI and PA (p < 0.05; n = 447). Skeletal MFI and abdominal visceral, but not subcutaneous, AT are inversely associated with SM mitochondrial bioenergetics in older adults independent of BMI. Associations between ectopic AT and in vivo mitochondrial bioenergetics are attenuated by PA.

A Retrospective Analysis of Southeastern U.S. Police Recruit Health and Fitness From 4 Points in Time Within a 16-Year Period: Implications for Physical Fitness Training.

Gonzales, SM, Orr, RM, Coburn, JW, Hoffmann, MD, Kennedy, K, Dawes, JJ, and Lockie, RG. A retrospective analysis of southeastern U.S. police recruit health and fitness from 4 points in time within a 16-year period: Implications for physical fitness training. J Strength Cond Res 38(6): 1118-1126, 2024-Drawing from the general population for its recruiting needs, police departments often employ academy curricula to improve a recruit's fitness so they can perform occupational tasks. Recently, obesity and physical inactivity have increased in the general population, potentially influencing the health and fitness of incoming recruits. This study involved a retrospective, cross-sectional analysis of health and fitness data of police recruits. Data from 1 police department in southeastern United States were analyzed at 4 specific time points, splitting the recruits into natural immerging groups; 2003 (n = 93), 2006 (n = 137), 2009 (n = 74), and 2019 (n = 242). Health and fitness data for all recruits included age, height, body mass, and body mass index (BMI); systolic and diastolic blood pressure (BP); sit-and-reach; combined grip strength; push-ups and sit-ups completed in 60 seconds; physical ability test time; and 2.4-km run time. Several univariate analyses, with sex and age as covariates (analyses of covariance), and a Bonferroni's post hoc, determined whether there were significant between-group differences. Effect sizes (d) were also calculated. Key results demonstrated that 2019 recruits were heavier than the recruits in 2006 and 2009 (p ≤ 0.032; d = 0.14-0.38); had a greater BMI (p ≤ 0.028; d = 0.24-0.75) and systolic BP (p < 0.001; d = 0.47-0.65), and lesser sit-and-reach distance (p ≤ 0.020; d = 0.26-0.46), than all recruit groups; completed fewer sit-up repetitions than the recruits in 2006 and 2009 (p ≤ 0.025; d = 0.42-0.48); and were slower in the 2.4-km run than the recruits in 2006 (p = 0.009; d = 0.36). Police training staff may need to address lesser health (BMI, BP) and fitness (hamstring flexibility, abdominal endurance, aerobic fitness) in incoming recruits.

소규모 초등학교 학생의 방과후학교 스포츠 활동 경험과 교육적 의미

Objectives The purpose of this study was to examine the after-school sports activity experiences of elementary school students in a small-scale setting and explore the educational implications of these experiences. Methods To achieve this, data were collected from 6 students in grades 3 to 6 who participated in after-school sports activities at a small-scale elementary school during the first semester from March to July 2023. Data col-lection involved participant observation, in-depth interviews, and document analysis. The data were analyzed us-ing iterative comparative analysis, and the credibility of the research was ensured through triangulation, peer dis-cussions, and confirmation from research participants. Results The students' experience in small-scale elementary school after-school sports activities is described as “Reviving the Spark of Small-Scale School Physical Education.” Due to insufficient preparation in regular physical education classes by homeroom teachers, students had lost interest. In response, after-school sports activities served the purpose of fulfilling the lack of physical activity, bridging care gaps, and providing enjoyable leisure time, positively impacting students' holistic development and self-realization. The educational significance is framed as “Illuminating the Torch of Public Education.” The collaborative format of after-school sports activities facilitated interaction between grade levels, fostering exchange among students. It provided opportunities for mutual learning and motivation between juniors and seniors. Additionally, it contributed to reducing private educa-tion expenses, restoring trust in public education, and offering a broad range of sports experiences. Conclusions The after-school sports activities in small-scale elementary schools provide students with oppor-tunities for growth and development on various levels. Therefore, the activation of physical education activities in small-scale elementary schools is necessary.

Determinant factors associated with central obesity in the academic staff at Universitas Negeri Gorontalo

Central obesity is one of the causes of metabolic syndrome and other degenerative diseases. This study aimed to analyze the relationship between age, gender, physical activity, genetics, stress, and diet with the incidence of central obesity in academic staff at Universitas Negeri Gorontalo. The research method used was an analytical observational method with a cross-sectional study design with the number of research subjects 248 samples consisting of employees or education personnel at Universitas Negeri Gorontalo. Data were collected using a questionnaire and analyzed using binary logistic regression analysis. The results showed that physical activity, genetics, stress, and calorie requirement had a significant relationship with central obesity, while age and gender did not. The calorie requirement variable had a p-value of 0.000 and an odds ratio of 10.75. The physical activity variable had a p-value of 0.009 with an odds ratio of 0.59. The stress variable has a p-value of 0.015 with an odds ratio of 2.09. The results of the data analysis test obtained an R-square value of 0.359. This indicates that the independent variable can explain or influence the dependent variable by 35.9%. The remaining 64.1% is explained by other variables not included in this study.

Neck pain among students of the faculty of medicine and pharmacy of Marrakech

Our objective was to investigate neck pain occurrence among students at the Faculty of Medicine and Pharmacy of Marrakech (FMPM), pinpoint its associated factors, and propose effective prevention strategies. Additionally, we aimed to evaluate its medical and psychological impact on physical activity and study quality. To achieve our goals, we conducted over three-month period a cross-sectional study among FMPM students from 2nd to 7th year, using a self-questionnaire with both descriptive and analytical purposes, from June 2022 to September 2022.We considered students with neck pain as those who had undergone an episode of neck pain within the previous year. Our research consisted of 206 students, with a gender ratio of 3.4 and an average age of 23 years. The results indicated that the vast majority of students (81.1%) had experienced neck pain within the past year, but for most, the pain lasted less than a week. During the survey, neck pain was reported by 18.4% of students. Our analysis discovered that there was a significant correlation between the occurrence of neck pain within the past year and age, family history of degenerative disc diseases, prior neck pain, amount of sleep, and computer use for studying. Through our research, we have confirmed that neck pain is a significant health issue for FMPM students. In order to address this problem and decrease its occurrence and impact, we have suggested preventative measures. To achieve this, we have put up posters in the faculty hall and shared a link online within student groups, which provides information on exercises and proper posture.

A mini-review on influence of physical exercise in remodeling the immune mechanism

Exercising on a regular basis has been associated with delay in onset of many lifestyle disorders and chronic conditions. Different types of exercise have varied effects on our innate immune cells, both positively and negatively. Low-intensity exercises like yoga or brisk walking, medium-intensity exercises like swimming or cycling, and long-term high-intensity exercises like playing sports like volleyball or working out in the gym are some examples. The immune system's function is impacted differently by exercise training depending on the type, duration, intensity, and other factors. Exercise training is a double-edged sword that helps the body's immune system by changing the immune cells' post-exercise reaction mechanisms. Regular physical exercise is one of the lifestyle adjustments aimed at minimizing morbidity and mortality associated with contemporary illnesses such as obesity, diabetes, cardiovascular disease, and cancer. Regular leisure exercise training is regarded to be beneficial, but extreme exercise, such as that performed by professional athletes, is thought to have possibly detrimental consequences. This review summarizes current information in the field of exercise-associated alterations of infection susceptibility and indicates knowledge gaps for further investigation. It highlights that long term effects of physical activity shows a positive association with longevity and exercise.

Visceral Adipose Tissue Reduction Measured by Deep Neural Network Architecture Improved Reflux Esophagitis Endoscopic Grade.

Visceral obesity is a risk factor for reflux esophagitis (RE). We investigated the risk of RE according to visceral adipose tissue (VAT) measured by deep neural network architecture using computed tomography (CT) and evaluated the longitudinal association between abdominal adipose tissue changes and the disease course of RE. Individuals receiving health checkups who underwent esophagogastroduodenoscopy (EGD) and abdominal CT at Seoul National University Healthcare System Gangnam Center between 2015 and 2016 were included. Visceral and subcutaneous adipose tissue areas and volumes were measured using a deep neural network architecture and CT. The association between the abdominal adipose tissue area and volume and the risk of RE was evaluated. Participants who underwent follow-up EGD and abdominal CT were selected; the effects of changes in abdominal adipose tissue area and volume on RE endoscopic grade were investigated using Cox proportional hazards regression. We enrolled 6,570 patients who underwent EGD and abdominal CT on the same day. RE was associated with male sex, hypertension, diabetes, excessive alcohol intake, current smoking status, and levels of physical activity. The VAT area and volume increased the risk of RE dose-dependently. A decreasing VAT volume was significantly associated with improvement in RE endoscopic grade (hazard ratio: 3.22, 95% confidence interval: 1.82-5.71). Changes in subcutaneous adipose tissue volume and the disease course of RE were not significantly correlated. Visceral obesity is strongly associated with RE. VAT volume reduction was prospectively associated with improvement in RE endoscopic grade dose-dependently. Visceral obesity is a potential target for RE treatment.

Psychological impact of the covid -19 pandemic on school age children

Introduction: The psychological impact of the COVID-19 pandemic on the general population has been widely studied. However, few studies have been carried out on children, even though they are experiencing a difficult situation and major stress that may expose them to significant psychological suffering. We are interested in how children perceive these emotional changes during the confinement associated with the COVID-19 pandemic. The aim is to understand the impact of the pandemic and containment on children. To do this, we assessed the prevalence of depression, anxiety and perceived post-traumatic stress in school-age children, looking for factors associated with these psychopathological dimensions with a view to better management and intervention to reduce the possible negative effects of this situation. Methodology: This is a cross-sectional study based on gathering information from all primary school pupils in Fez, who responded freely and voluntarily. The study was carried out over a period of two months, from June 2020 to August 2020, using an online self-questionnaire and psychometric evaluation scales: QIPS, CDI, CRIES-13. Results: 330 students met our inclusion criteria. The mean age of our participants was 8.68 ± 1.94 years, with a minimum of 6 years and a maximum of 12 years. There was a slight female predominance, with 168 girls (50.9%) and 162 boys (49.1%). Most of the pupils (95.2%) lived in urban areas, 92.7% of the children had married parents, and 64.5% of our participants had parents with a university education. Almost half of the children had a family income of more than Dhs10,000 per month. Only 2.1% of the children had a psychiatric history, 16.7% of the children had a history of somatic illness, 22.1% of the participants had a family psychiatric history, 11.2% of our participants had experienced a stressful event in their lives and 22.1% had parents who had previously experienced a stressful event. Evaluation of the CRIES-13 scale showed that 39.4% had a positive score of over 30 in favour of significant symptoms of post-traumatic stress disorder, a probable depressive state (CDI score&gt;15) was revealed in 26.1% of the children, and with regard to anxiety disorder, the mean score in our sample was 32.27 (±8.147) with a median of 29. The analytical study showed a statically significant relationship between certain socio-demographic characteristics, namely: parents' low level of education, living with divorced parents, low monthly family income and negative psychological impact during the pandemic. On the other hand, female gender was correlated with the occurrence of anxiety. Our study also revealed other correlations, notably between the presence of a personal history of psychiatric or somatic illness and the occurrence of depression, family psychiatric history, and the experience of a stressful event by the child and parents were factors strongly associated with the three psychological disorders studied. Factors related to the child's lifestyle, such as the practice of physical activity at home, a daily study period of less than 2 hours, and dissatisfaction with distance learning, were associated with psychological distress during confinement. In addition, certain personality traits seemed to be implicated in the worsening of this condition during confinement: the presence of a relative with covid-19, the child's knowledge of the pandemic, and the fear that the pandemic would continue. Conclusion: The COVID-19 pandemic has had a severe impact on the general public, particularly children, psychological interventions identifying and targeting children at risk are urgently needed, and future studies are warranted to design and evaluate the effectiveness of interventions.

Effects on Function and Enjoyment of Aquatic Therapy in Children with Cerebral Palsy: A Pilot Study in a Special Education School

ABSTRACT Cerebral palsy (CP) is a disorder of movement and posture resulting from a non-progressive injury to the developing brain. The aim of the study was to determine the functional level of performance in water and enjoyment of children with CP, after participating in aquatic therapy classes. Nine children diagnosed with CP were involved in an eight-month aquatic program based on the Halliwick concept and provided as a part of a special school education program. The outcome measurements were the Water Orientation Test Alyn (WOTA 1) and an original enjoyment questionnaire. The data showed a statistically significant improvement in six out of 13 trials of WOTA 1. The children described aquatic therapy as joyful, easy, and their favourite form of physical activity among those offered by the school. The results suggest that aquatic therapy classes can be effectively used among children with CP to improve body position control and mental adjustment in the water.

Home-based tele-exercise training and physical activity during the COVID-19 pandemic in chronic kidney disease patients.

The coronavirus disease 2019 (COVID-19) pandemic and lockdown reduced physical activity levels in hemodialysis (HD) patients and kidney transplant recipients (KTRs). This study aimed to describe physical activity levels during lockdown and assess the effects of an online home-based exercise training program on physical activity levels in HD patients and KTRs. Forty-five HD patients and thirty-five KTRs were divided into four groups: exercise groups 1 (ΕΧ-HD) and 2 (EX-KTR) followed a 4-month tele-exercise training program, while control groups received usual care. All participants at baseline and at the end of the study completed the International Physical Activity Questionnaire (IPAQ), while their daily physical activity levels were recorded via a step counting application. At the end of the study, the repeated measures analysis revealed a significant effect of time, group, and time-by-group interaction in the average steps per day, walking, and moderate activity for the exercise-HD group (p < 0.05). Similarly, the analysis revealed a notable effect of time, group, and time-by-group interaction in the exercise-KTR group in average daily steps, vigorous and walking activity (p < 0.05). Multiple regression analysis showed that the level of physical activity at the end of the study was related to the urban place of residence and theparticipation in the 4-month exercise program of both HD patients and KTRs. Participation in a tele-exercise training program led to favorable effects on physical activity levels both in HD patients and KTRsduring lockdown.

Physical activity, sedentary behavior, and the risk of functional gastrointestinal disorders: A two-sample Mendelian randomization study.

Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are prevalent functional gastrointestinal disorders (FGIDs). In this study we aimed to explore the causal association between physical activity or sedentary behavior and the risk of FD and IBS. Mendelian randomization (MR) analysis was employed. Candidate genetic instruments for physical activity and sedentary behavior were retrieved from the latest published Genome-Wide Association Study (GWAS), which included up to 703,901 participants. Summary-level GWAS data for FD (8 875 cases and 320 387 controls) and IBS (9 323 cases and 301 931 controls) were obtained from the FinnGen study. The causal effects were mainly estimated by inverse variance weighted (IVW) method. Sensitivity analyses were implemented with Cochran's Q test, MR-Egger intercept test, leave-one-out analysis, and the funnel plot. No significant association of moderate-to-vigorous intensity physical activity (MVPA), leisure screen time (LST), sedentary behavior at work (SDW), and sedentary commuting (SDC) with the risk of FD was found. However,there was a suggestive correlation between MVPA and the decreased risk of FD (odds ratio [OR] 0.63, 95% confidence interval [CI] 0.39-0.99, P = 0.047). Genetically predicted MVPA decreased the risk of IBS (OR 0.58, 95% CI 0.40-0.84, P = 0.004), while increased LST was positively associated with IBS risk (OR 1.33, 95% CI 1.15-1.53, P < 0.001). No causal effects of SDW or SDC on IBS risk were observed. MVPA and LST are causally linked to the development of IBS, which will facilitate primary prevention of IBS.

Highlighting Unseen Activity Through 48-Hour Continuous Measurement in Subacute Stroke Rehabilitation: Preliminary Cohort Study.

Motor impairments not only lead to a significant reduction in patient activity levels but also trigger a further deterioration in motor function due to deconditioning, which is an issue that is particularly pronounced during hospitalization. This deconditioning can be countered by sustaining appropriate activity levels. Activities that occur outside of scheduled programs, often overlooked, are critical in this context. Wearable technology, such as smart clothing, provides a means to monitor these activities. This study aimed to observe activity levels in patients who had strokes during the subacute phase, focusing on both scheduled training sessions and other nontraining times in an inpatient rehabilitation environment. A smart clothing system is used to simultaneously measure heart rate and acceleration, offering insights into both the amount and intensity of the physical activity. In this preliminary cohort study, 11 individuals undergoing subacute stroke rehabilitation were enrolled. The 48-hour continuous measurement system, deployed at admission and reassessed 4 weeks later, monitored accelerometry data for physical activity (quantified with a moving SD of acceleration [MSDA]) and heart rate for intensity (quantified with percent heart rate reserve). The measurements were performed using a wearable activity monitoring system, the hitoe (NTT Corporation and Toray Industries, Inc) system comprising a measuring garment (wear or strap) with integrated electrodes, a data transmitter, and a smartphone. The Functional Independence Measure was used to assess the patients' daily activity levels. This study explored factors such as differences in activity during training and nontraining periods, correlations with activities of daily living (ADLs) and age, and changes observed after 4 weeks. A significant increase was found in the daily total MSDA after the 4-week program, with the average percent heart rate reserve remaining consistent. Physical activity during training positively correlated with ADL levels both at admission (ρ=0.86, P<.001) and 4 weeks post admission (ρ=0.96, P<.001), whereas the correlation between age and MSDA was not significant during training periods at admission (ρ=-0.41, P=.21) or 4 weeks post admission (ρ=-0.25, P=.45). Conversely, nontraining activity showed a negative correlation with age, with significant negative correlations with age at admission (ρ=-0.82, P=.002) and 4 weeks post admission (ρ=-0.73, P=.01). Inpatient rehabilitation activity levels were positively correlated with ADL levels. Further analysis revealed a strong positive correlation between scheduled training activities and ADL levels, whereas nontraining activities showed no such correlation. Instead, a negative correlation between nontraining activities and age was observed. These observations suggest the importance of providing activity opportunities for older patients, while it may also suggest the need for adjusting the activity amount to accommodate the potentially limited fitness levels of this demographic. Future studies with larger patient groups are warranted to validate and further elucidate these findings.

Relationship between skeletal mitochondrial function and digital markers of free-living physical activity in older adults.

This study examined the association between in vivo skeletal mitochondrial function and digital free-living physical activity patterns-a measure that summarizes biological, phenotypic, functional, and environmental effects on mobility. Among 459 participants (mean age 68years; 55% women) in the Baltimore Longitudinal Study of Aging, mitochondrial function was quantified as skeletal muscle oxidative capacity via post-exercise phosphocreatine recovery rate (τPCr) in the vastus lateralis muscle of the left thigh, using 31P magnetic resonance spectroscopy. Accelerometry was collected using a 7-day, 24-h wrist-worn protocol and summarized into activity amount, intensity, endurance, and accumulation patterning metrics. Linear regression, two-part linear and logistic (bout analyses), and linear mixed effects models (time-of-day analyses) were used to estimate associations between τPCr and each physical activity metric. Interactions by age, sex, and gait speed were tested. After covariate adjustment, higher τPCr (or poorer mitochondrial function) was associated with lower activity counts/day (β = - 6593.7, SE = 2406.0; p = 0.006) and activity intensity (- 81.5 counts, SE = 12.9; p < 0.001). For activity intensity, the magnitude of association was greater for men and those with slower gait speed (interaction p < 0.02 for both). Conversely, τPCr was not associated with daily active minutes/day (p = 0.15), activity fragmentation (p = 0.13), or endurance at any bout length (p > 0.05 for all). Time-of-day analyses show participants with high τPCr were less active from 6:00 a.m. to 12:00 a.m. than those with low τPCr. Results indicate that poorer skeletal mitochondrial function is primarily associated with lower engagement in high intensity activities. Our findings help define the connection between laboratory-measured mitochondrial function and real-world physical activity behavior.

The mediating effect of sleep duration on metabolic syndrome severity in adults: a structural equation modeling approach

BackgroundMetabolic syndrome (MetS) is associated to sleep duration. It is crucial to identify factors that disrupt sleep regulation. The study aimed to assess the indirect effect of risk factors related to MetS severity through sleep duration by utilizing a structural equation model (SEM).MethodsThe study involving 3,935 adults from the baseline data of the Ravansar Non-Communicable Disease (RaNCD) cohort study. MetS severity scores were the outcome variables. SEM was employed to explore the relationships, utilizing IBM SPSS and AMOS version 23.ResultsThe mean MetS severity score was higher in women compared to men (0.25 vs. 0.16, P = 0.003). In men, socioeconomic status (SES) has a positive direct effect (β = 0.048) and a negative indirect effect (β=-0.006) on MetS severity. Increased physical activity is directly (β=-0.036) and indirectly (β=-0.093) associated with reducing MetS severity. Nap duration is directly linked to an increase (β = 0.072) but has an indirect effect (β=-0.008) in decreasing MetS severity. In women, SES has a direct (β=-0.020) and indirect (β=-0.001) inverse relationship with MetS severity. Increased physical activity is directly (β=-0.048) and indirectly (β=-0.036) associated with decreasing MetS severity in women. Nap duration is directly associated with an increase in MetS severity (β=-0.018) but indirectly contributes to its reduction (β=-0.002). Sleep duration not only directly affects MetS severity but is also influenced by age, SES, physical activity, obesity and nap duration.ConclusionPhysical activity, SES, and nap duration directly and indirectly effect the MetS severity. Sleep duration was recognized as a mediating variable that supports the indirect effects.

Effect of COVID-19 pandemic on bioimpedance health indicators in young adults.

Herein, we investigate the relationships between the COVID-19 pandemic and overcoming the virus, and its effects on body composition parameters in young adults from Slovakia. We assessed 773 adults aged 18 to 30 years in pandemic-status sub-groups. Individual lifestyles and overcoming the COVID-19 effects were evaluated by a detailed questionnaire, and body composition parameters were analyzed using the InBody 770 bioimpedance analyzer. Statistically significant lower values were observed in the male group during the pandemic for the following parameters; proteins and minerals, fat free mass (FFM), skeletal muscle mass (SMM), lean body mass (LBM) and its values in the right and left arm and trunk, total body water (TBW) and its values in the right and left arm and trunk, body cell mass (BCM), basal metabolic rate (BMR) and phase angle (PA). The regression analysis confirmed the negative pandemic effect and the negative impact of COVID-19 on men in the following parameters: proteins (p = .027 for pandemic and p = .005 for COVID-19), FFM (p = .023 for pandemic and p = .005 for COVID-19), LBM (p = .022 for pandemic and p = .004 for COVID-19), SMM (p = .028 for pandemic and p = .005 for COVID-19), TBW (p = .020 for pandemic and p = .004 for COVID-19), BMR (p = .024 for pandemic and p = .005 for COVID-19) and PA (p = .009 for pandemic). Physical activity was a further significant predictor in men for all the above parameters. We observed significantly lower body composition parameters associated with fat free mass in young adult men during the pandemic than before it. However, future research is warranted to determine if these effects have long-term significance.

Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort

BackgroundHealthy lifestyles are inversely associated with the risk of noncommunicable diseases, which are leading causes of death. However, few studies have used longitudinal data to assess the impact of changing lifestyle behaviours on all-cause and cancer mortality.MethodsWithin the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, lifestyle profiles of 308,497 cancer-free adults (71% female) aged 35–70 years at recruitment across nine countries were assessed with baseline and follow-up questionnaires administered on average of 7 years apart. A healthy lifestyle index (HLI), assessed at two time points, combined information on smoking status, alcohol intake, body mass index, and physical activity, and ranged from 0 to 16 units. A change score was calculated as the difference between HLI at baseline and follow-up. Associations between HLI change and all-cause and cancer mortality were modelled with Cox regression, and the impact of changing HLI on accelerating mortality rate was estimated by rate advancement periods (RAP, in years).ResultsAfter the follow-up questionnaire, participants were followed for an average of 9.9 years, with 21,696 deaths (8407 cancer deaths) documented. Compared to participants whose HLIs remained stable (within one unit), improving HLI by more than one unit was inversely associated with all-cause and cancer mortality (hazard ratio [HR]: 0.84; 95% confidence interval [CI]: 0.81, 0.88; and HR: 0.87; 95% CI: 0.82, 0.92; respectively), while worsening HLI by more than one unit was associated with an increase in mortality (all-cause mortality HR: 1.26; 95% CI: 1.20, 1.33; cancer mortality HR: 1.19; 95% CI: 1.09, 1.29). Participants who worsened HLI by more than one advanced their risk of death by 1.62 (1.44, 1.96) years, while participants who improved HLI by the same amount delayed their risk of death by 1.19 (0.65, 2.32) years, compared to those with stable HLI.ConclusionsMaking healthier lifestyle changes during adulthood was inversely associated with all-cause and cancer mortality and delayed risk of death. Conversely, making unhealthier lifestyle changes was positively associated with mortality and an accelerated risk of death.

A Multidisciplinary Approach: Management and Rehabilitation of Children With Pediatric Post-COVID-19 Condition.

Post-COVID-19 condition in children is a still largely unknown syndrome with a diverse pattern of symptoms, which can have a major impact on daily life. Currently, there are no evidence-based proven treatments, and the focus is on symptom management and recovery of daily functioning. A multidisciplinary, tailored approach is recommended, with attention to energy management and activity building, where the main goal should be a return to baseline levels of cognitive, physical and social activity.

Secular Trends in Adherence to Healthy Behaviors Among US Adults with Diabetes, 1999-2018.

Adherence to healthy lifestyle is essential for diabetes management in light of the plateaued metabolic control, diversifying causes of death, and continued excess mortality among people with diabetes (PWD). This study aims to assess the secular trend of adherence to healthy behaviors among PWD in NHANES, a nationally representative survey of Americans using a stratified, multistage probability design in 2-year cycles since 1999. Adherence to healthy lifestyle was estimated using never smoking, moderate drinking, adequate physical activity, and healthy diet, and the score ranged 0-4. Among 7410 participants, adherence to healthy behaviors across time slightly increased from 1.4 (95% CI, 1.3 to 1.5) in 1999-2002 to 1.6 (1.5 to 1.8) in 2015-2018 (Ptrend = 0.002). The non-Hispanic Blacks caught up with the non-Hispanic Whites in overall lifestyle score (1.7 vs. 1.6 in 2015-2018), while large socioeconomic disparities remained in that participants with higher income and education level, and covered by health insurance were more likely to have adherence to healthy behaviors. As the metabolic control plateaued and causes of death have diversified among PWD, our findings suggested a great potential of lifestyle modification in facilitating the long-term health of these patients.