Moderate Association Research Articles

The Roles of Identity Centrality and Affirmation in the Associations Between Discrimination and Mental Health Among Bi+ Adults

Bi+ individuals are at increased risk for mood and anxiety disorders compared to heterosexual and lesbian/gay individuals in part due to unique experiences of discrimination. Minority stress theory posits that associations between discrimination and adverse mental health outcomes may be stronger for those with higher identity centrality and lower identity affirmation, but few studies have tested these hypotheses. Therefore, the current study examined whether identity centrality and affirmation moderated the associations between discrimination and depression and anxiety symptoms among 715 bi+ adults. In bivariate analyses, discrimination was positively associated with depression and anxiety symptoms, whereas identity centrality and affirmation were not significantly associated with either. However, in multivariate analyses, identity centrality and affirmation were negatively associated with depression and anxiety symptoms, respectively. Neither identity centrality nor affirmation moderated any associations. These findings raise the question whether identity characteristics moderate associations between discrimination and mental health, but replication is needed.

Depositional model of the Holocene coquinas - Albardão platform, southern Brazil

For the past decade, giant deepwater oil discoveries in the pre-salt section of the Campos and Santos basins of Brazil, have brought significant attention to offshore exploration activities along the South Atlantic margins. The prolific Cretaceous coquina deposits in these basins are part of the pre-salt rock record and constitute an effective but complex and heterogeneous hydrocarbon reservoir difficult to predict and model. Parting from this context, an evaluation of the sedimentological, structural and taphonomic criteria for coquinas are essential to better understand and predict the facies distribution and depositional models of the pre-salt coquinas strata. Based on this premise, the present work aims to genetically interpret 133 mixed carbonate-siliciclastic bottom sediments of the Albardão shelf – a modern marine coquina analogue, using facies description, investigating the relationship with hydrodynamic forces, and accessing the influence of morphology and structural framework on their deposition. From these analyses, we recognized a hybrid facies, three modern carbonate facies in analogy to the carbonate rock classification and four siliciclastic facies. These eight facies were then grouped into three facies associations representing high, moderate, and low energy facies. The high energy facies association comprises rudstones (Rf) and grainstones (Gf) with highly fragmented bivalve shells and barnacles abundantly present in the beach system, above the fair-weather wave base limit (FWWB). These facies also occur offshore on bathymetric highs above the storm wave base limit (SWB) but display less reworking than the coastal high energy facies above the FWWB due to wave shoaling. The moderate energy facies association consists of hybrid sand (Hs), sand (S) and muddy sand (mS) occurring between the FWWB and SWB limits in the offshore transition zone with extensive winnowing action and low rate of reworking. The low energy facies association includes sandy mud (sM), mud (M) and micritic mud (Mc), characterized by the decantation of the fine sediments below the offshore SWB limit. The results confirm a bottom facies distribution controlled by depth, shelf profile morphology and energy from incident waves. The fragmented rudstone and fragmented grainstone facies are the best-recognized reservoirs with both having high porosity and high permeability.

Validation of an abbreviated Big Five personality inventory at large population scale: Psychometric structure and associations with common psychiatric and neurological disorders

BackgroundThe five-factor model of personality, as quantified using instruments such as the Big Five Inventory, consists of broad personality domains including Extraversion, Agreeableness, Conscientiousness, Neuroticism (emotional instability), and Openness. Such instruments typically include >40 items. However, instruments with many items can be unwieldly and a cause of measurement error in clinical and cohort studies where multiple scales are sequenced. Conversely, established 5- and 10-item versions of the Big Five Inventory have poor reliability. Here, we developed and validated an abbreviated 18-item Big Five Inventory that balances efficiency, reliability and sensitivity. MethodWe analysed three datasets (N = 59,797, N = 21,177, and N = 87,983) from individuals who participated in the online Great British Intelligence Test (GBIT) study, a collaborative citizen science project with BBC2 Horizon. We applied factor analyses (FA), predictive normative modelling, and one-sample t-tests to validate the 18-item version of the Big Five and to investigate its associations with psychiatric and neurological conditions. ResultsThe 18-item version of the Big Five Inventory had higher validity and retest reliability compared to the other previously shortened versions in the literature, with comparable demographic associations to the full Big Five Inventory. It exhibited strong (i.e. large effect size) associations with psychiatric conditions, and moderate (small-medium) associations with neurological conditions. Neuroticism (emotional instability) was substantially higher in all psychiatric conditions, whereas Conscientiousness, Openness and Extraversion showed differential associations across conditions. ConclusionThe newly validated 18-item version of the Big Five provides a convenient means of measuring personality traits that is suitable for deployment in a range of studies. It retains psychometric structure, retest reliability and clinical-group sensitivity, as compared to the full original scale.

Variation in leaf morphology and architecture, phytochemical content, and antioxidant capacity among 36 Camellia sinensis clones of the Indian sub-Himalayan region

Camellia sinensis, renowned as the second most widely consumed nonalcoholic beverage worldwide, bears substantial economic importance, prompting cultivators to breed various clones for enhanced flavor and quality. This study analyzed the variation in leaf phenotype, phytochemicals (total tannins and proanthocyanidins content) and antioxidant potential of 36 widely cultivated tea clones from India’s sub-Himalayan region using multivariate analysis. Results indicated that TV23 had the largest leaf and SS27 and RR had the smallest. TS520 was the richest in tannin, proanthocyanidins, and antioxidants, while S3A1 and Heeleakah were the least. Principal components analysis (PCA) and cluster analysis unveiled four morphological clusters (representative clones - TV1, TV23, TV30, 124.48.8) and four phytochemical clusters (representative clones - TS520, TV9, TV27, P126). GC-MS analysis revealed that TV1 and TV30 had high caffeine content (82.0%), while TS520 exhibited abundant antioxidant compounds, including sycllo-inositol (23.84%) and epigallocatechin (4.23%). TS520’s exceptional antioxidant properties, confirmed by DPPH, ABTS, and total antioxidant capacity assays, may result from its cultivation through seed propagation. Correlation analysis showed antioxidant potential had moderate negative associations with leaf size, strong negative with inter-secondary vein number, and positive with petiole length. This study is pivotal for assessing tea clone diversity, with broader applications in tea improvement and breeding programs.

Exploring the Role of Mental Preparedness and Emotional Competence in Nurturing Academic Success among Students in the Post-Pandemic Instructional Landscape

This study examines the relationship between students' mental preparedness, emotional competence, and their academic success in the context of the reintroduction of full in-person instructional setup after a hiatus of almost three years. Using a descriptive correlational research design, the study aimed to provide a comprehensive understanding of these variables. The Grade 11 students from Langgal National High School were selected as the respondents. The findings highlight the significant influence of mental preparedness on students' performance in academic activities, underscoring the importance of being mentally prepared to address learning challenges, especially in the context of the pandemic. Additionally, the study reveals a moderate association between the level of emotional competence and academic success, emphasizing its role as a personal resource in adapting to the learning environment. Overall, the results suggest that students' mental preparedness and emotional competence during full in-person classes significantly contribute to their likelihood of achieving academic success.

Autonomy-supportive parenting as a moderator of associations between ethnic and racial identity processes and psychological adjustment during college.

The purpose of this study was to test the roles of ethnic and racial identity (ERI) processes and autonomy-supportive parenting on college students' psychological adjustment. American college students of color (N = 505) completed questionnaires assessing ERI exploration and commitment, autonomy-supportive parenting, and psychological adjustment (self-esteem, depressive symptoms). Key variables were operationalized as latent constructs, and main and interaction effects were tested using the latent moderated structural equation modeling approach. Higher levels of ERI commitment (but not exploration) and parental autonomy support each uniquely predicted higher levels of self-esteem and lower levels of depressive symptoms. Parental autonomy support moderated associations between ERI processes and psychological adjustment, and the nature of moderation did not differ across Black and Latino/a/x students. Supporting the psychological adjustment of college students of color necessitates acknowledging the importance of both parental and institutional efforts to encourage students' autonomy strivings and ERI processes. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

The Relation Between Perceived Mental Effort, Monitoring Judgments, and Learning Outcomes: A Meta-Analysis

Accurately monitoring one’s learning processes during self-regulated learning depends on using the right cues, one of which could be perceived mental effort. A meta-analysis by Baars et al. (2020) found a negative association between mental effort and monitoring judgments (r = -.35), suggesting that the amount of mental effort experienced during a learning task is usually negatively correlated with learners’ perception of learning. However, it is unclear how monitoring judgments and perceptions of mental effort relate to learning outcomes. To examine if perceived mental effort is a diagnostic cue for learning outcomes, and whether monitoring judgments mediate this relationship, we employed a meta-analytic structural equation model. Results indicated a negative, moderate association between perceived mental effort and monitoring judgments (β = -.19), a positive, large association between monitoring judgments and learning outcomes (β = .29), and a negative, moderate indirect association between perceived mental effort and learning outcomes (β = -.05), which was mediated by monitoring judgments. Our subgroup analysis did not reveal any significant differences across moderators potentially due to the limited number of studies included per moderator category. Findings suggest that when learners perceive higher levels of mental effort, they exhibit lower learning (confidence) judgments, which relates to lower actual learning outcomes. Thus, learners seem to use perceived mental effort as a cue to judge their learning while perceived mental effort only indirectly relates to actual learning outcomes.

Physical activity levels and sedentary behaviour according to sex, age, BMI, academic year, and country among medical students in Latin America

Physical inactivity represents a global challenge in public health, being the second most significant factor contributing to mortality. In Latin America, the prevalence of physical inactivity and sedentary behaviour is notable, affecting medical students as well, who play a crucial role as behavioural role models for the population. This study addresses the prevalence of physical activity and sedentary behaviour among medical students in Latin America during the year 2023. A total of 864 participants from 12 institutions across eight countries were surveyed using the Global Physical Activity Questionnaire. Significant variations in physical activity and sedentary behaviour were observed according to sex, age, body mass index, academic year, and country. Notably, Costa Rica exhibited the highest levels of moderate physical activity in leisure time (90 min/day). Strength training was more common among men (60 min/day) and in Argentina (60 min/day). Sedentary behaviour was higher in women (420 min/day) and during the first academic year (485 min/day). Uruguay stood out with high levels of sedentary behaviour (600 min/day). Correlations indicated positive moderate associations between academic year and moderate leisure-time PA (r:0,128, p:0,007). In conclusion, there are associations between the level of physical activity and sedentary behaviour with the variables studied in this research, with the main findings being that the female sex has more time spent in sedentary behaviour (minutes/day) and less time spent in strength training (minutes/day). Additionally, there are higher levels of sedentary behaviour in the early years of medical study compared to the later years of the program.

Systematic review and meta-analysis of Chinese coach leadership and athlete satisfaction and cohesion.

This meta-analysis investigates the relationship between coach leadership behaviors and athlete satisfaction and group cohesion within the realm of Chinese sports. The study also explores player sex and player classification as potential moderating variables. The primary focus is on evaluating the impact of coaching behaviors, as measured by the Leadership Scale for Sports, on athlete satisfaction and group cohesion. Standard literature searches from China National Knowledge Infrastructure and Wanfang academic databases produced 26 studies encompassing a total of 319 effect sizes and a participant pool of 7,121 athletes across various sports. Using the Comprehensive Meta-Analysis (CMA) to examine relevant data, results reveal a moderate and positive association between coach leadership and athlete satisfaction (ES = 0.412). Specifically, training and instruction (ES = 0.531), positive feedback (ES = 0.526), social support, and democratic decision-making exhibit positive effects, while autocratic behavior demonstrates a marginal positive effect. Similarly, a moderate positive relationship is identified between coach leadership and overall group cohesion (ES = 0.275), with training and instruction (ES = 0.396), social support (ES = 0.356), positive feedback, and democratic behavior positively influencing cohesion. Conversely, autocratic behavior has a small negative impact on cohesion. Furthermore, female athletes (ES = 0.603) and professional players (ES = 0.544) display stronger positive associations between coach leadership and satisfaction. These findings highlight the significance of diverse coaching behaviors aligned with player characteristics for fostering positive athlete satisfaction and group cohesion within the Chinese sports context, offering valuable guidance to Chinese coaches aiming to enhance their coaching strategies.

Identity Characteristics as Moderators of Discrepancy on Well-being

Research finds that discrepancies between individuals’ self-views and their perceptions of how others view them decrease psychological well-being. According to identity theory, certain characteristics of identities may exacerbate the impact of discrepancy on well-being, while stress process theory suggests they may have the opposite, weakening effect. Using telephone survey data from a national probability sample of adults, I investigate whether several identity characteristics—subjective importance of an identity (prominence), extensiveness (interactional commitment) and intensiveness of ties (affective commitment) to others that are based on an identity, and the potential costs of failing to fulfill the role obligations of an identity (role-based commitment)—moderate associations between discrepancy and well-being (depressive symptoms and self-esteem) in two types of identities (obligatory and voluntary). I find that identity commitment buffers the effects of discrepancy in obligatory identities and exacerbates the effects of discrepancy in voluntary identities. Implications of these findings are discussed.

Race and ethnicity moderate the associations between lifetime psilocybin use and past year hypertension.

Hypertension is a major source of morbidity and mortality worldwide, particularly for racial and ethnic minorities who face higher rates of hypertension and worse health-related outcomes. Recent research has reported on protective associations between classic psychedelics and hypertension; however, there is a need to explore how race and ethnicity may moderate such associations. We used data from the National Survey on Drug Use and Health (2005-2014) to assess whether race and ethnicity moderate the associations between classic psychedelic use - specifically psilocybin - and past year hypertension. Hispanic identity moderated the associations between psilocybin use and past year hypertension. Furthermore, individuals who used psilocybin and identified as Non-Hispanic White had reduced odds of hypertension (aOR: 0.83); however, these associations were not observed for any other racial or ethnic groups in our study for individuals who used psilocybin. Overall, our results demonstrate that the associations between psychedelics and hypertension may vary by race and ethnicity. Longitudinal studies and clinical trials can further advance this research and determine whether such differences exist in causal contexts. https://osf.io/xsz2p/?view_only=0bf7b56749034c18abb2a3f8d3d4bc0b.

The gut-brain axis in individuals with alcohol use disorder: Anexploratory study of associations among clinical symptoms, brain morphometry, and the gut microbiome.

Alcohol use disorder (AUD) is commonly associated with distressing psychological symptoms. Pathologic changes associated with AUD have been described in both the gut microbiome and brain, but the mechanisms underlying gut-brain signaling in individuals with AUD are unknown. This study examined associations among the gut microbiome, brain morphometry, and clinical symptoms in treatment-seeking individuals with AUD. We performed a secondary analysis of data collected during inpatient treatment for AUD in subjects who provided gut microbiome samples and had structural brain magnetic resonance imaging (MRI; n = 16). Shotgun metagenomics sequencing was performed, and the morphometry of brain regions of interest was calculated. Clinical symptom severity was quantified using validated instruments. Gut-brain modules (GBMs) used to infer neuroactive signaling potential from the gut microbiome were generated in addition to microbiome features (e.g., alpha diversity and bacterial taxa abundance). Bivariate correlations were performed between MRI and clinical features, microbiome and clinical features, and MRI and microbiome features. Amygdala volume was significantly associated with alpha diversity and the abundance of several bacteria including taxa classified to Blautia, Ruminococcus, Bacteroides, and Phocaeicola. There were moderate associations between amygdala volume and GBMs, including butyrate synthesis I, glutamate synthesis I, and GABA synthesis I & II, but these relationships were not significant after false discovery rate (FDR) correction. Other bacterial taxa with shared associations to MRI features and clinical symptoms included Escherichia coli and Prevotella copri. We identified gut microbiome features associated with MRI morphometry and AUD-associated symptom severity. Given the small sample size and bivariate associations performed, these results require confirmation in larger samples and controls to provide meaningful clinical inferences. Nevertheless, these results will inform targeted future research on the role of the gut microbiome in gut-brain communication and how signaling may be altered in patients with AUD.

Use of natural environments is associated with reduced inequalities in child mental wellbeing: A cross-sectional analysis using global positioning system (GPS) data

Exposure to natural environments may benefit child mental wellbeing whilst offering a lever to reduce health inequalities. However, understanding of these relationships is limited by evidence from indirect measures of exposure. We objectively measured children’s direct use of natural environments—and use in low or high physical activity (PA) states—and associated this with their mental wellbeing. We then examined moderation by sex and household income.Using global positioning system and accelerometry data from children (n = 640), we measured mean daily time in natural environments (‘total use’), which we stratified by PA level as ‘passive use’ (sedentary and light PA) and ‘active use’ (moderate and vigorous PA). Logistic regression associated exposures with dichotomised Strengths and Difficulties Questionnaire outcomes (internalising difficulties; externalising difficulties; prosocial behaviour), with interactions to examine moderation.A 10-minute increase in total use was associated with 10.5 % lower risk of abnormal internalising outcomes (OR: 0.895; 95 % CI 0.809, 0.990), and 13.2 % lower risk of abnormal externalising outcomes (OR: 0.868; 95 % CI 0.776, 0.990). This suggests that ∼ 60 min of daily total use was associated with 50 % lower risk of abnormal internalising and externalising outcomes. The relative effects of passive and active use were equal, but their associations were moderated by income independently for specific outcomes. For externalising outcomes, the risk of abnormal scores in lower-income children reduced as passive use increased (P = 0.027) but remained constant for higher-income children. For prosocial outcomes, the likelihood of normal scores increased with active use in lower-income children, but not higher-income children (P = 0.005). Sex did not moderate these associations.The findings suggest that targeted interventions supporting disadvantaged children to use natural environments could help address inequalities in mental wellbeing. Further, the moderated associations with types of use suggest the equigenic effects of natural environments may operate through multiple pathways.

Does Social Support Play a Role in the Expression and Everyday Functioning Impact of Apathy in HIV Disease?

Clinically notable apathy occurs in approximately one-third of persons living with HIV (PLWH). Drawing from psychological theory, this cross-sectional study examined the interplay between apathy and social support in persons with (n = 143) and without (n = 61) HIV disease. Analyses were conducted using multiple regression and mediation procedures with 95th percentile bootstrap confidence intervals. Positive HIV serostatus and lower social support were associated with more frequent apathy, independent of other mood symptoms. Social support did not moderate apathy's associations with everyday functioning among PLWH, but post hoc analyses revealed that apathy mediated the relationship between social support and everyday functioning among PLWH. Stronger social support may provide a buffer against the frequency of apathy symptoms in persons with and without HIV disease. The relationship between lower social support and poorer everyday functioning in HIV might be partly explained by apathy. Longitudinal research is needed to examine the mechanisms of these relationships.

Gender as a moderator of associations between military sexual trauma and posttraumatic stress disorder treatment utilization.

The present study sought to investigate whether gender moderates the relationship between military sexual trauma (MST) and posttraumatic stress disorder (PTSD) treatment utilization, among veterans with clinically significant PTSD symptoms. Participants were 2,664 veterans with probable PTSD from a nationwide, population-based survey. Participants reported sociodemographic information, history of MST (including military sexual harassment and military sexual assault), and lifetime receipt of PTSD psychotherapy and medication treatment. We found that gender significantly moderated relationships between (a) military sexual harassment and PTSD psychotherapy, (b) military sexual assault and PTSD psychotherapy, and (c) military sexual harassment and PTSD medication. For women, MST was associated with a greater likelihood of receiving treatment, but for men, MST was not associated with PTSD treatment. Future research is needed to better understand gender differences in how experiences of MST may affect engagement in PTSD treatment. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

The Bed Bridge Test: a new functional test for hospital inpatients – a feasibility and measurement study

Purpose To develop and assess the Bed Bridge Test’s (BBT) feasibility, safety, and clinimetric properties and evaluate functional capacity in hospitalised patients. Materials and methods This feasibility and measurement study examined four BBT versions, including the timed-limited at 30 and 60 s and repetition-limited at 5 and 10 times, in hospitalised patients in a university hospital in Brazil. Ninety-two functionally stable patients with respiratory, gastrointestinal, or post-surgical conditions participated. Participants completed the BBT versions in a random order. BBT concurrent criterion validity was evaluated using the Short Physical Performance Battery (SPPB), Sit-to-Stand (STS) test, and Functional Status Score (FSS). Results The participants were 51 ± 17 years old, 60% female, and 66% with clinical conditions. All participants completed the BBT versions without adverse events. Test–retest reliability was good–excellent (intraclass correlation coefficient >0.87) for all BBT versions, with acceptable agreement parameters and minimal detectable changes. The time-limited versions of the BBT might be affected by a ceiling effect. Floor effects were minimal for all BBT versions. BBT showed moderate associations with SPPB and STS and weak associations with FSS. Conclusions The BBT is feasible and has promising measurement properties.

Tackling digital payment frauds: a study of consumer preparedness in India

Purpose This paper aims to present a study to measure “Consumer Preparedness” (CP) towards digital payment frauds by considering factors such as awareness regarding fraud risk (“Awareness”), implementation of measures (“Protection”) and actions to be taken in case of fraud (“Responsiveness”). Design/methodology/approach This study reviews existing literature to understand various typologies of digital payment fraud. The data of 372 consumers was collected using a structured questionnaire. The data was analyzed using analysis of variance (ANOVA) and Chi-square. CP score was calculated based on awareness score, protection score and responsiveness score. Findings The study shows that the score for the level of awareness was low, for the level of protection was moderate and for the level of responsiveness was high, leading to an overall moderate level of preparedness. Further, a moderate association was observed between demographic factors and the level of preparedness. Practical implications The authors recommend proactive and reactive measures for Central Banks regarding central fraud registry and intelligence exchange, consumer fraud vulnerability assessment model and mandating fraud risk management controls. Further, financial institutions are recommended to permit payment from registered devices only, implement strong customer authentication (including biometric authentication) and conduct periodic awareness sessions. Originality/value The existing body of knowledge does not have a model or scoring mechanism to assess the preparedness of consumers to tackle digital payment fraud. The research paper adds a classification of fraud typologies and an exploratory approach to measure the CP score.

4-6 Repetition Maximum (RM) and 1-RM Prediction in Free-Weight Bench Press and Smith Machine Squat Based on Body Mass in Male Athletes.

Dhahbi, W, Padulo, J, Russo, L, Racil, G, Ltifi, M-A, Picerno, P, Iuliano, E, and Migliaccio, GM. Four- to 6-repetition maximum and 1-repetition maximum estimation in free-weight bench press and smith machine squat based on body mass in male athletes. J Strength Cond Res 38(8): 1366-1371, 2024-This study aimed to explore the feasibility and face validity of predicting maximum strength 1 repetition maximum (1-RM) and 4-6 RM in athletes across different sports specialties, based on the relationship between muscle strength and BM. One hundred fifteen male athletes, aged 23.63 ± 6.77 years and participating in diverse sports specialties, were included in this study. Muscle strength was assessed using the 4-6 RM and 1-RM tests in free-weight bench press (BP) and Smith machine squat (SQ) exercises, whereas BM was measured using a portable digital scale. A linear regression equation based on muscle strength and BM was performed. The 4-6 RM and 1-RM scores showed excellent intersession relative reliability (intraclass correlation coefficient (2,1) : 0.946-0.989) and absolute reliability (CV: 3.4-4.7%) in both BP and SQ exercises. In addition, the magnitude of the relationship and the coefficients used to estimate the 4-6 RM and 1RM, based on BM, differed among the subjects when they are grouped according to their sports specialties ( R2 ranged from non-significant to 0.998). Overall, the 4-6 RM test showed a stronger correlation with BM ( R : 0.655 for SQ and R : 0.683 for BP) than the 1RM ( R : 0.552 for SQ and R : 0.629 for BP), and the general (i.e., not sport-specific) 4 to 6-RM prediction equations should be preferred over sport-specific ones because they are statistically more robust due to the larger sample size. In conclusion, the 4-6 RM can be predicted from BM with high reliability, a moderate association, and a prediction error that, when considering the 4-6 RM as a starting point for estimating of the 1RM, can be considered entirely acceptable in practical settings.

Psychometric evaluation of the patient-reported experience of cognitive impairment in schizophrenia (PRECIS) scale

BackgroundCognitive impairment associated with schizophrenia (CIAS) represents a distinct, persistent, and core group of schizophrenia symptoms. Cognitive symptoms have been shown to have an impact on quality of life. There are several published CIAS measures, but none based on direct patient self-report. It is important to capture the patient’s perspective to supplement performancebased outcome measures of cognition to provide a complete picture of the patient’s experience. This paper describes additional validation work on the Patient-Reported Experience of Cognitive Impairment in Schizophrenia (PRECIS) instrument.MethodsData from two large, international, pharmaceutical clinical trials in medically and psychiatrically stable English-speaking patients with schizophrenia and 88 healthy controls were analyzed. An exploratory factor analysis (EFA) was conducted in one trial (n = 215), using the original 35-item PRECIS. The factor structure suggested by EFA was further evaluated using item response theory (IRT; Samejima’s graded response model), and tested using confirmatory factor analysis (CFA). Both EFA and CFA results were tested in a second trial with similar inclusion/exclusion characteristics (n = 410). Additional statistical properties were evaluated in healthy controls.ResultsEFA suggested that the best solution after item reduction suggested a factor structure of 6 factors based on 26 items (memory, communication, self-control, executive function, attention, sharpness of thought), supporting a total score, with an additional 2-item bother score (28 items in all). IRT analysis indicated the items were well-ordered within each domain. The CFA demonstrated excellent model fit, accounting for 69% of the variance. The statistical properties of the 28-item version of the PRECIS were confirmed in the second trial. Evidence for internal consistency and test-retest reliability was robust. Known-groups validity was supported by comparison of healthy controls with patients with schizophrenia. Correlations indicated moderate associations between PRECIS and functioning instruments like the Schizophrenia Cognition Rating Scale (SCoRS), but weak correlations with performance-based outcomes like MATRICS Consensus Cognitive Battery (MCCB).DiscussionUsing two clinical trial samples, we identified a robust factor structure for the PRECIS and were able to replicate it in the second sample. Evaluation of the meaningful score difference (MSD) should be repeated in future studies, as these samples did not show enough change for it to be evaluated.ConclusionsThis analysis provides strong evidence for the reliability and validity of the PRECIS, a 28-item, patient-reported instrument to assess cognitive impairment associated with schizophrenia. The correlation with functioning and the weak correlation with performance on cognitive tasks suggests that patient reports of cognitive impairment measure a unique aspect of patient experience.

Longitudinal associations of diabetes-specific family conflict and diabetes management in adolescents with type 1 diabetes.

Diabetes-specific family conflict is a risk factor for diabetes indicators (e.g., higher hemoglobin A1c (HbA1c), lower adherence), but little longitudinal data are available to understand associations across time. To better inform targets and timing of interventions, we examined (a) whether fluctuations in conflict covary with diabetes indicators within adolescents across time; (b) whether reciprocal associations exist; and (c) whether aspects of the parent-adolescent relationship (e.g., parental acceptance) buffer associations across time. Adolescents (N = 235, ages 11.5-15.5 at baseline, 53.6% female) completed measures of diabetes-related conflict with mothers and with fathers (separately), parental acceptance, and adherence every 6 months across 1 year (three time points). HbA1c was obtained from medical records. Data were collected in 2009. Bivariate between-person correlations indicated that at each time point, adolescents who reported more conflict with mothers and fathers also had higher HbA1c and lower adherence. Within-person correlations (fluctuations across three time points) indicated that fluctuations in conflict with mothers were associated with fluctuations in HbA1c but not adherence. Actor-partner multilevel models indicated that fluctuations in family conflict at each time point were not associated with future diabetes indicators. Parental acceptance did not moderate associations of family conflict and diabetes indicators. While findings corroborate extant literature noting that adolescents with high average diabetes-specific family conflict may benefit from interventions designed to reduce conflict, conflict at one time point may not be predictive of future diabetes indicators. (PsycInfo Database Record (c) 2024 APA, all rights reserved).