It is essential to elucidate the shear mechanical behavior of structural planes to assess the risk to rock masses and protect them from shear failure. Current research on shear mechanical behavior is focused on isotropic structural planes with the same lithology on both sides. However, anisotropic structural planes, commonly found in nature, may exhibit unique mechanical behavior that differs from isotropic structural planes. Therefore, it is necessary to study the factors affecting the shear strength of the anisotropic structural planes. In this paper, the direct shear numerical tests on anisotropic structural planes were carried out using the three-dimensional distinct element code (3DEC) based on the laboratory test. The numerical test results illustrate that the error between the peak shear strength of the numerical test and the laboratory test is basically within 10%. The shear stress-displacement curves of the numerical and laboratory tests are similar, which verifies the accuracy of the numerical test. According to the Barton standard sections, anisotropic structural plane models with different roughness and size were established, and the direct shear numerical tests with different normal stresses were carried out. To predict the peak shear strength of the anisotropic structural planes, one hundred and eighty-one sets of direct shear numerical test data were selected. Normal stress, roughness, compressive strength of soft and hard rock masses, basic friction angle of soft and hard rock masses, and structural plane size were used as input parameters to establish a back propagation (BP) neural network model. The research results show that, under identical conditions, the shear strength of the anisotropic structural planes decreases as the structural plane size increases. On the contrary, the shear strength increases with the increasing structural plane roughness and normal stress. For the BP neural network prediction model, the root mean square error (RMSE) and coefficient of determination (R2) of the training set are 0.441 and 0.957. For the test set, the RMSE is 0.489, and R2 is 0.947, which indicates that the predicted values are in good agreement with the actual values.
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