The multi-strip method is often used to establish a demand model for fragility analysis. Using the multi-strip method to scale the ground motion record may cause uncertainty and bias in structural response calculation and fragility assessment. It is necessary to analyze the effect of differences in the amplitude scaling range in different strips on structural seismic response calculation and seismic fragility assessment. In this paper, the multi-strip method was used to analyze the seismic demand bias based on four multi-story reinforced concrete frame structures subjected to eight ground motion record sets. The bias, variance, and coefficient of variation in different strips in each group of ground motion records were obtained. The effect of different strips on the demand bias was investigated by analysis of variance (ANOVA). Uncertainty quantification of structural demand and fragility curves was carried out using the bootstrap sampling method. The results for structures in different ground motion record sets verify that the differences between the demand bias for different strips by amplitude scaling are statistically insignificant for a 95% confidence level. These findings will contribute to the use of scaling methods for ground motion record sets in a probabilistic seismic demand assessment, allowing for a more reliable prediction of structural seismic fragility.
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