This study aims to develop a new artificial intelligence model for analyzing and evaluating slope stability in open-pit mines. Indeed, a novel hybrid intelligent technique based on an optimization of the cubist algorithm by an evolutionary method (i.e., PSO), namely PSO-CA technique, was developed for predicting the factor of safety (FS) in slope stability; 450 simulations from the Geostudio software for the FS of a quarry mine (Vietnam) were used as the datasets for this aim. Five factors include bench height, slope angle, angle of internal friction, cohesion, and unit weight were used as the input variables for estimating FS in this work. To clarify the performance of the proposed PSO-CA technique in slope stability analysis, SVM, CART, and kNN models were also developed and assessed. Three performance indices, such as mean absolute error (MAE), root-mean-squared error (RMSE), and determination coefficient (R2), were computed to evaluate the accuracy of the predictive models. The results clarified that the proposed PSO-CA technique was the most dominant accuracy with an MAE of 0.009, RMSE of 0.025, and R2 of 0.981, in estimating the stability of slope. The remaining models (i.e., SVM, CART, kNN) obtained poorer performance with MAE from 0.014 to 0.038, RMSE 0.030–0.056, and R2 0.917–0.974.
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