application of interactive technologies to realize personalized learning in biology and ecology classes in the 10th grade. This methodology comprises three main stages: organizational-preparatory, technological, and concluding. Pedagogical conditions are justified for the effective implementation of the respective methodology, including creating a success-oriented situation, organizing a positive psychological microclimate, gearing up for work, motivating students’ cognitive activities, equipping the classroom, providing visualization aids for the lesson, selecting effective methods of communication and instructional interaction, discussing the action algorithm during work, reviewing assessment criteria, reflection, and summarizing.Based on the above, a functional model for the implementation of the developed methodology is proposed. On the basis of the above, a functional model for the formation of a successful student in education, who will achieve high levels of academic achievement in biology and ecology when using personalized learning with interactive technology, is proposed. The functional model for the formation of a successful student in education, who will achieve high levels of academic achievement in biology and ecology when using personalized learning with interactive technology, is based on a scientific approach to organizing the educational process.The main goal of this model is the effective implementation of personalized learning with the use of interactive technologies, which allows for the formation of a successful student on the basis of student-centeredness, which is the driving force behind raising the level of academic achievement in biology and ecology.