Diagnosis Model Research Articles

REVIEW OF THE BOOK "A MODEL FOR DIAGNOSIS AND PREVENTION OF AGGRESSIVENESS IN THE BEHAVIOR OF ELEMENTARY SCHOOL-AGE STUDENTS

The review presents the monograph of Chief. Associate Professor Simona Nikolova, PhD "Model for diagnosis and prevention of aggressiveness in the behavior of primary school students", which is distinguished by relevance, given the dynamic and often extreme situation in the educational environment. The topic focuses on the need to prevent aggressiveness in the behavior of children of primary school age, as a form of overcoming negative manifestations in their behavior. The proposed model methodologically offers an idea for the work of the school psychologist with students of primary school age with the aim of developing cognitive and emotional skills for communicating with peers, developing empathic abilities and opportunities to evaluate others' behavior. The proposed program offers, in terms of content, the immediate work of the psychologist with the children in a real school environment.

Diagnosis of Pancreatic Ductal Adenocarcinoma Using Deep Learning.

Recent advances in artificial intelligence (AI) research, particularly in image processing technologies, have shown promising applications across various domains, including health care. There is a significant effort to use AI for the early diagnosis and detection of diseases, offering cost-effective and timely solutions to enhance patient outcomes. This study introduces a deep learning network aimed at analyzing pathology images for the accurate diagnosis of pancreatic cancer, specifically pancreatic ductal adenocarcinoma (PDAC). Utilizing a novel dataset comprised of cases diagnosed with PDAC and/or chronic pancreatitis, this study applies deep learning algorithms to assess the effectiveness and reliability of the diagnostic process. The dataset was enhanced through image duplication and the creation of a second dataset with varied dimensions, facilitating the training of advanced transfer learning models including InceptionV3, DenseNet, ResNet, VGG, EfficientNet, and a specially designed deep neural network. The study presents a convolutional neural network model, optimized for the rapid and accurate detection of pancreatic cancer, and conducts a comparative analysis with other models to select the most accurate algorithm for a decision support system. The results from Dataset 1 show that EfficientNetB0 achieved a high success rate of 92%. In Dataset 2, VGG16 was found to have high performance, with a success rate of 92%. On the other hand, ResNet50 achieved a remarkable success rate of 96% despite a moderate training time and showed high precision, recall, F1 score, and accuracy. These results provide valuable data to demonstrate and share the relevance of different deep learning models in pancreatic cancer diagnosis.

Integrated bagging-RF learning model for diabetes diagnosis in middle-aged and elderly population

As the population ages, the increase in the number of middle-aged and older adults with diabetes poses new challenges to the allocation of resources in the healthcare system. Developing accurate diabetes prediction models is a critical public health strategy to improve the efficient use of healthcare resources and ensure timely and effective treatment. In order to improve the identification of diabetes in middle-aged and older patients, a Bagging-RF model is proposed. In the study, two diabetes datasets on Kaggle were first preprocessed, including unique heat coding, outlier removal, and age screening, after which the data were categorized into three age groups, 50–60, 60–70, and 70–80, and balanced using the SMOTE technique. Then, the machine learning classifiers were trained using the Bagging-RF integrated model with eight other machine learning classifiers. Finally, the model’s performance was evaluated by accuracy, F1 score, and other metrics. The results showed that the Bagging-RF model outperformed the other eight machine learning classifiers, exhibiting 97.35%, 95.55%, 95.14% accuracy and 97.35%, 97.35%, 95.14% F1 Score at the Diabetes Prediction Dataset for diabetes prediction for the three age groups of 50–60, 60–70, and 70–80; and 97.03%, 94.90%, 93.70% accuracy and 97.03%, 94.90%, 93.70% F1 Score at the Diabetes Prediction Dataset. 95.55%, 95.13% F1 Score; and 97.03%, 94.90%, 93.70% accuracy; and 97.03%, 94.89%, 93.70% F1 Score at Diabetes Prediction Dataset. In addition, while other integrated learning models, such as ET, RF, Adaboost, and XGB, fail to outperform Bagging-RF, they also show excellent performance.

Vibration Signal Analysis for Intelligent Rotating Machinery Diagnosis and Prognosis: A Comprehensive Systematic Literature Review

Many industrial processes, from manufacturing to food processing, incorporate rotating elements as principal components in their production chain. Failure of these components often leads to costly downtime and potential safety risks, further emphasizing the importance of monitoring their health state. Vibration signal analysis is now a common approach for this purpose, as it provides useful information related to the dynamic behavior of machines. This research aimed to conduct a comprehensive examination of the current methodologies employed in the stages of vibration signal analysis, which encompass preprocessing, processing, and post-processing phases, ultimately leading to the application of Artificial Intelligence-based diagnostics and prognostics. An extensive search was conducted in various databases, including ScienceDirect, IEEE, MDPI, Springer, and Google Scholar, from 2020 to early 2024 following the PRISMA guidelines. Articles that aligned with at least one of the targeted topics cited above and provided unique methods and explicit results qualified for retention, while those that were redundant or did not meet the established inclusion criteria were excluded. Subsequently, 270 articles were selected from an initial pool of 338. The review results highlighted several deficiencies in the preprocessing step and the experimental validation, with implementation rates of 15.41% and 10.15%, respectively, in the selected prototype studies. Examination of the processing phase revealed that time scale decomposition methods have become essential for accurate analysis of vibration signals, as they facilitate the extraction of complex information that remains obscured in the original, undecomposed signals. Combining such methods with time–frequency analysis methods was shown to be an ideal combination for information extraction. In the context of fault detection, support vector machines (SVMs), convolutional neural networks (CNNs), Long Short-Term Memory (LSTM) networks, k-nearest neighbors (KNN), and random forests have been identified as the five most frequently employed algorithms. Meanwhile, transformer-based models are emerging as a promising venue for the prediction of RUL values, along with data transformation. Given the conclusions drawn, future researchers are urged to investigate the interpretability and integration of the diagnosis and prognosis models developed with the aim of applying them in real-time industrial contexts. Furthermore, there is a need for experimental studies to disclose the preprocessing details for datasets and the operational conditions of the machinery, thereby improving the data reproducibility. Another area that warrants further investigation is differentiation of the various types of fault information present in vibration signals obtained from bearings, as the defect information from the overall system is embedded within these signals.

Deep learning model for diagnosis of thyroid nodules with size less than 1 cm: A multicenter, retrospective study

ObjectiveTo develop a ultrasound images based dual-channel deep learning model to achieve accurate early diagnosis of thyroid nodules less than 1 cm. MethodsA dual-channel deep learning model called thyroid nodule transformer network (TNT-Net) was proposed. The model has two input channels for transverse and longitudinal ultrasound images of thyroid nodules, respectively. A total of 9649 nodules from 8455 patients across five hospitals were retrospectively collected. The data were divided into a training set (8453 nodules, 7369 patients), an internal test set (565 nodules, 512 patients), and an external test set (631 nodules, 574 patients). ResultsTNT-Net achieved an area under the curve (AUC) of 0.953 (95 % confidence interval (CI): 0.934, 0.969) on the internal test set and 0.941 (95 % CI: 0.921, 0.957) on the external test set, significantly outperforming traditional deep convolutional neural network models and single-channel swin transformer model, whose AUCs ranged from 0.800 (95 % CI: 0.759, 0.837) to 0.856 (95 % CI: 0.819, 0.881). Furthermore, feature heatmap visualization showed that TNT-Net could extract richer and more energetic malignant nodule patterns. ConclusionThe proposed TNT-Net model significantly improved the recognition capability for thyroid nodules with size less than 1 cm. This model has the potential to reduce overdiagnosis and overtreatment of such nodules, providing essential support for precise management of thyroid nodules while complementing fine-needle aspiration biopsy.

Detection of clavicle fracture after martial arts training based on 3D segmentation and multi-perspective fusion

To improve the diagnosis efficiency of clavicle fractures, a Diagnosis Model of Clavicle Fracture Based on 3D Segmentation and Multi Perspective Fusion (3Ds MPF) is proposed in the experiment. By performing 3D segmentation on clavicle images, key layer images are extracted, and multi-perspective image data are fused and output to achieve accurate classification and diagnosis results. The results show that on the relevant dataset, the loss function value of the constructed model is less than 0.01, and the calculation accuracy is as high as 0.999. The average classification accuracy in actual use exceeds 90%, and it can capture the majority of fracture features in clavicle computed tomography images. The above results indicate that the model constructed by the research institute can significantly improve the judgment efficiency of computed tomography images, which helps to enhance the detection and diagnosis of clinical fracture conditions. The experimental results have helped improve the clinical diagnostic efficiency of fracture detection work.

Research on the Assistive Strategy of Medical Image Segmentation Technology based on Medical Transformer Model in Intelligent Diagnosis of Tuberculosis in Xinjiang Region

Research on the Assistive Strategy of Medical Image Segmentation Technology based on Medical Transformer Model in Intelligent Diagnosis of Tuberculosis in Xinjiang Region

Survey on Adversarial Attack and Defense for Medical Image Analysis: Methods and Challenges

Deep learning techniques have achieved superior performance in computer-aided medical image analysis, yet they are still vulnerable to imperceptible adversarial attacks, resulting in potential misdiagnosis in clinical practice. Oppositely, recent years have also witnessed remarkable progress in defense against these tailored adversarial examples in deep medical diagnosis systems. In this exposition, we present a comprehensive survey on recent advances in adversarial attacks and defenses for medical image analysis with a systematic taxonomy in terms of the application scenario. We also provide a unified framework for different types of adversarial attack and defense methods in the context of medical image analysis. For a fair comparison, we establish a new benchmark for adversarially robust medical diagnosis models obtained by adversarial training under various scenarios. To the best of our knowledge, this is the first survey paper that provides a thorough evaluation of adversarially robust medical diagnosis models. By analyzing qualitative and quantitative results, we conclude this survey with a detailed discussion of current challenges for adversarial attack and defense in medical image analysis systems to shed light on future research directions. Code is available on GitHub.

Artificial intelligence (AI)-enhanced electrocardiography: a machine-learning model for differential diagnosis between hypertrophic cardiomyopathy, cardiac amyloidosis and Anderson-Fabry disease

Abstract Background The differential diagnosis between Hypertrophic Cardiomyopathy (HCM) and phenocopies is challenging and relies on a comprehensive approach, which includes clinical and instrumental data, as well as laboratory exams and genetic testing. In this setting, 12-lead electrocardiogram (ECG) represents a valuable tool, but although typical patterns have been described, their diagnostic ability to discriminate between different etiologies is limited and requires considerable clinical experience. However, a correct diagnosis is of pivotal importance, allowing the prompt initiation of phenotype-specific therapies and consequently improving patient survival. Purpose Aim of this study was to develop a machine-learning model based on human-based ECG features to support the differential diagnosis between HCM, Cardiac Amyloidosis (CA) and Anderson-Fabry Disease (AFD). Methods We retrospectively examined ECGs of 200 patients, 50 affected by HCM, 100 affected by CA (50 AL CA and 50 transthyretin CA) and 50 with a diagnosis of AFD cardiomyopathy. The patients were then divided in sinus rhythm (SR) subgroup (158 patients) and atrial fibrillation (AF) subgroup (42 patients). For each subgroup, patients were randomly split into a training (80%) and a testing cohort (20%), and a random forest (RF) model was trained on the training cohort, with hyperparameter tuning via 10-fold cross validation. The resulting model was then tested on the testing cohort to assess its predictive accuracy. Results Both RF models (SR and AF) showed good discriminative performance in this multiclass classification task on the testing cohort [SR: accuracy 67%; multiclass area under the curve (AUC) 0.797, 95% confidence interval (CI) 0.472 -0.827; AF: accuracy 75%; multiclass AUC 0.792, 95% CI 0.349 – 0.968]. Figure 1 and figure 2 report for each model the rank of the most important variables for class prediction. Conclusions An AI-based ECG interpretation based on human-derived ECG features can predict the etiology underlying an hypertrophic phenotype, helping to perform a correct diagnosis and consequently to set a specific therapeutic process.

Integrated Analysis of Gut microbiome, Inflammation and Neuroimaging Features Supports the Role of Microbiome-Gut-Brain Crosstalk in Schizophrenia

Abstract Background and Hypothesis Gut microbiota has been implicated in the pathogenesis of schizophrenia (SZ) and relevant changes in the brain, but the underlying mechanism remains elusive. This study aims to investigate the microbiota-gut-brain crosstalk centered on peripheral inflammation in SZ patients. Study Design We recruited a cohort of 182 SZ patients and 120 healthy controls (HC). Multi-omics data, including fecal 16S rRNA, cytokine data, and neuroimaging data, were collected and synthesized for analysis. Multi-omics correlations and mediation analyses were utilized to determine the associations of gut microbiome with inflammatory cytokines and neuroimaging characteristics. Additionally, machine learning models for effective SZ diagnosis were separately generated based on gut microbial and neuroimaging data. Study Results Gut microbial dysbiosis, characterized by a decrease in butyrate-producing bacteria and an increase in pro-inflammatory bacteria, has been identified in SZ patients. These key microbial taxa were associated with increased inflammatory cytokines, potentially through mediating lipid metabolic pathways such as steroid biosynthesis and linoleic acid metabolism. Further analysis revealed altered microbial genera to be correlated with disrupted gray matter volume and regional homogeneity in SZ patients. Importantly, certain inflammatory cytokines mediated the relationship between the SZ-enriched genus Succinivibrio and aberrant activity of anterior cingulate cortex and left inferior temporal gyrus in the SZ group. Moreover, the classification model based on gut microbial data showed comparable efficacy to the model based on brain functional signatures in SZ diagnosis. Conclusions This study presents evidence for the dysregulated microbiota-gut-brain axis in SZ and emphasizes the central role of peripheral inflammation.

ECGWiz: a unified and generalizable AI model for comprehensive ECG diagnosis

Abstract Background Deep learning has demonstrated diagnostic performance in electrocardiogram (ECG) analysis comparable to that of clinicians. However, existing models primarily excel in diagnosing common conditions such as arrhythmias and heart blocks, which are easily identifiable using standard predictor variables. Conversely, models aiming to uncover novel insights, such as detecting structural changes or the presence of myocardial scar, often lack generalizability due to insufficient data, model architecture limitations, and other factors. Moreover, these models frequently encounter challenges, such as a decline in performance when applied to external datasets. To address these issues comprehensively, we propose the ECGWiz — a unified model capable of tackling diverse ECG-related problems with consistently high performance. Objective To develop a generalizable Foundation AI model for ECG diagnosis capable of detecting diverse cardiac abnormalities and diseases using few training samples. Methods We utilized publicly available datasets like PTB-XL, CPSC, etc. To build our model, totaling approximately 80,000 ECGs. These 12 lead ECGs are scaled and filtered before using them for training. The AI model is pretrained using Self Supervised Learning and Contrastive Learning strategies. Further, the model undergoes supervised training using a hierarchy of labels that increase in granularity, encompassing arrhythmias, heart blocks, other cardiac abnormalities, heart failure, sudden cardiac death and more. Lastly, the model is prepared for Few-Shot Learning — where the model learns from a minimal set of samples (5 to 10 ECGs) of the target disease. For testing the model, we are using unique datasets like PROSE which consists of non-ischemic cardiomyopathy patients with and without myocardial scaring detected using cardiac MRI imaging at the Johns Hopkins University. Results Our model, trained on a dataset of only 5 ECG recordings, demonstrated a 74% accuracy in identifying myocardial scarring as detected by LGE MRI, utilizing a standard 12-lead ECG. This performance is comparable to that of conventional deep learning methods, which necessitate datasets containing upwards of 120 ECG recordings. Conclusion Our model represents a promising stride in creating a unified and adaptable foundation AI model for comprehensive ECG-based diagnosis. Its capacity to learn from a minimal set of examples signifies a robust framework that can evolve and adapt to new challenges in ECG diagnosis. Ongoing improvements, particularly through dataset expansion, underscore its potential to enhance cardiovascular diagnostics, offering precise and efficient patient care.

Development and validation of a risk prediction model for worsening renal function in patients with incident heart failure

Abstract Background Worsening renal function (WRF) is one of the strongest predictors of outcome in patients with heart failure (HF). The presence of WRF often influences the decision to start, up-titrate, or discontinue disease modifying HF therapies and is one of the key determinants of suboptimal guideline-directed medical therapy. Existing WRF risk scores were developed in hospitalised HF patients to predict in-hospital WRF. Their performance among incident HF is far from ideal. It is therefore important to develop a new WRF risk prediction model in people with newly diagnosed HF. Purpose This study was to develop and validate a clinical risk prediction model for 180-day WRF post diagnosis of incident HF using data from a population-based longitudinal cohort. Methods We developed and validated a multivariable logistic regression model for WRF in the 180 days post diagnosis of incident HF. Data for individuals with incident HF between 2016 to 2021 were extracted from the NELSON study conducted in Tayside, Scotland. WRF was defined as a composite event of (i) having two consecutive eGFRs declined by 40% or greater; (ii) having an eGFR < 15mL/min/1.73m2; (iii) initiation of sustained dialysis; (iv) development of end-stage kidney disease; (v) receiving kidney transplantation; or (vi) kidney related death. Four candidate models included one model using literature knowledge; one multivariable fractional polynomial (MFP) model; and two stepwise selected models based on either Akaike or Bayesian information criterion (AIC or BIC). Calibration and discrimination were assessed, and performance stability were evaluated using optimism corrected performance via 1000 times bootstrapping. Results 4076 individuals (mean age 72.8 ± 13.2; 58% male; 1081 HF with reduced ejection fraction (HFrEF), 646 with HF with mildly reduced ejection fraction (HFmrEF), 1348 HF with preserved ejection fraction (HFpEF), and 1001 HF with unknown ejection fraction (EF)) who were WRF-free when diagnosed with HF were identified. Of these, 2095 (51.4%) were in-patients, and 1981 (48.6%) were out-patients. 285 (7%) patients developed WRF within 180 days post HF diagnosis. The selected MFP model (comprising 12 predictors, Table 1) showed good calibration (slope = 1.00 [0.86, 1.14]; intercept = 0.0 [-0.13, 0.13]) discrimination (C-statistic = 0.69 [95% CI: 0.65, 0.72]), and stability (optimism corrected: calibration slope = 0.94 [0.80, 1.07]; calibration intercept = -0.14 [-0.50, 0.20]; C-statistic = 0.67 [0.64, 0.71]). Discrimination of the developed model significantly outperformed two existing risk scores (Forman and Basel, both with a C-statistic = 0.62 [0.59 – 0.65]). Conclusions We have shown that the developed model performed better in predicting WRF in individuals with newly diagnosed HF. This could have utility in identifying at risk patients with HF early in the disease trajectory for therapies that can reduce renal decline.Calibration of predicted riskModel estimates for predicting 180d WRF

Identification of new phenotypes in type 2 diabetes with acute myocardial infarction: toward a precision medicine?

Abstract Background Type 2 diabetes mellitus (T2DM) is a highly heterogeneous entity, with multiple subgroups differing by clinic presentation, disease progression and risk of complications such as myocardial infarction (MI). A new T2DM phenotyping classification has been recently proposed to help to improve treatment tailoring and target early treatments, and we aimed to identify the prevalence and characteristics of the new phenotypes. Methods All consecutive adults with a history T2DM hospitalized in a french Coronary Intensive Care Unit for an acute MI between February 1st, 2021 and January 31st, 2023 were included. Clusters were based on six variables (glutamate decarboxylase antibodies, age at diagnosis, BMI, HbA1c, and homoeostatic model assessment 2 estimates of β-cell function and insulin resistance). We stratified patients into five subgroups : 1/ SAID=severe autoimmune diabetes; 2/ SIDD=severe insulin-deficient diabetes; 3/ SIRD=severe insulin-resistant diabetes; 4/ MOD=mild obesity-related diabetes; and 5/ MARD=mild age-related diabetes. Results Among the 266 patients included, characteristics according to diabetes phenotypes are summarized in the Table. Conclusions Our prospective study showed that in real-world T2DM patients with acute MI, unclassical phenotypes, i.e. hyperinsulinaemic and insulinopaenic were common. Given the large discrepancies in characteristics, our findings suggest the relevance of the new substratification. However, its clinical utlity and translation in tailored treatment strategies and prognosis remains to be determined.Table.

Developing a Reproducible Radiomics Model for Diagnosis of Active Crohn's Disease on CT Enterography Across Annotation Variations and Acquisition Differences.

To systematically identify radiomics features on CT enterography (CTE) scans which can accurately diagnose active Crohn's disease across multiple sources of variation. Retrospective study of CTE scans curated between 2013 and 2015, comprising 164 subjects (65 male, 99 female; all patients were over the age of 18) with endoscopic confirmation for the presence or absence of active Crohn's disease. All patients had three distinct sets of scans available (full and reduced dose, where the latter had been reconstructed via two different methods), acquired on a single scanner at a single institution. Radiomics descriptors from annotated terminal ileum regions were individually and systematically evaluated for resilience to different imaging variations (changes in dose/reconstruction, batch effects, and simulated annotation differences) via multiple reproducibility measures. Multiple radiomics models (by accounting for each source of variation) were evaluated in terms of classifier area under the ROC curve (AUC) for identifying patients with active Crohn's disease, across separate discovery and hold-out validation cohorts. Radiomics descriptors selected based on resiliency to multiple sources of imaging variation yielded the highest overall classification performance in the discovery cohort (AUC = 0.79 ± 0.04) which also best generalized in hold-out validation (AUC = 0.81). Performance was maintained across multiple doses and reconstructions while also being significantly better (p < 0.001) than non-resilient descriptors or descriptors only resilient to a single source of variation. Radiomics features can accurately diagnose active Crohn's disease on CTE scans across multiple sources of imaging variation via systematic analysis of reproducibility measures. Clinical utility and translatability of radiomics features for diagnosis and characterization of Crohn's disease on CTE scans will be contingent on their reproducibility across multiple types and sources of imaging variation.

Fault migration diagnosis method for rolling bearing based on 2D convolutional neural network

ABSTRACT In recent years, the development of mechanical systems has gradually become larger and more complex. As one of the most critical components of mechanical systems, the health status of rolling bearings is crucial for the safe and orderly operation of the entire mechanical system. Therefore, this paper constructs a transfer diagnosis model based on two-dimensional convolutional neural networks, achieving efficient and fast cross working condition fault transfer diagnosis of rolling bearings. In summary, this article takes rolling bearings as the research object and constructs a fault diagnosis model under working condition migration by combining two-dimensional convolutional neural networks with maximum mean difference. Based on the constructed model, experiments are designed and signal data is collected for model training, validation, and testing. This article aims to achieve cross working condition transfer diagnosis of rolling bearings by combining the constructed model with real data from the test bench, providing reference and guidance for cross domain fault diagnosis of rolling bearings in practical engineering. The research results indicate that the constructed transfer diagnosis model based on two-dimensional convolutional neural network has achieved efficient and fast fault transfer diagnosis of rolling bearings across working conditions. The accuracy of the model in the frequency domain of transfer under 6 working conditions is higher than 98.15%.

Deep Learning With Optical Coherence Tomography for Melanoma Identification and Risk Prediction.

Malignant melanoma is the most severe skin cancer with a rising incidence rate. Several noninvasive image techniques and computer-aided diagnosis systems have been developed to help find melanoma in its early stages. However, most previous research utilized dermoscopic images to build a diagnosis model, and only a few used prospective datasets. This study develops and evaluates a convolutional neural network (CNN) for melanoma identification and risk prediction using optical coherence tomography (OCT) imaging of mice skin. Longitudinal tests are performed on four animal models: melanoma mice, dysplastic nevus mice, and their respective controls. The CNN classifies melanoma and healthy tissues with high sensitivity (0.99) and specificity (0.98) and also assigns a risk score to each image based on the probability of melanoma presence, which may facilitate early diagnosis and management of melanoma in clinical settings.

Conditional Generative Adversarial Networks with Optimized Machine Learning for Fault Detection of Triplex Pump in Industrial Digital Twin

In recent years, digital twin (DT) technology has garnered significant interest from both academia and industry. However, the development of effective fault detection and diagnosis models remains challenging due to the lack of comprehensive datasets. To address this issue, we propose the use of Generative Adversarial Networks (GANs) to generate synthetic data that replicate real-world data, capturing essential features indicative of health-related information without directly referencing actual industrial DT systems. This paper introduces an intelligent fault detection and diagnosis framework for industrial triplex pumps, enhancing fault recognition capabilities and offering a robust solution for real-time industrial applications within the DT paradigm. The proposed framework leverages Conditional GANs (CGANs) alongside the Harris Hawk Optimization (HHO) as a metaheuristic method to optimize feature selection from input data to enhance the performance of machine learning (ML) models such as Bagged Ensemble (BE), AdaBoost (AD), Support Vector Machine (SVM), K-Nearest Neighbors (KNNs), Decision Tree (DT), and Naive Bayes (NB). The efficacy of the approach is evaluated using key performance metrics such as accuracy, precision, recall, and F-measure on a triplex pump dataset. Experimental results indicate that hybrid-optimized ML algorithms (denoted by “ML-HHO”) generally outperform or match their classical counterparts across these metrics. BE-HHO achieves the highest accuracy at 95.24%, while other optimized models also demonstrate marginal improvements, highlighting the framework’s effectiveness for real-time fault detection in DT systems, where SVM-HHO attains 94.86% accuracy, marginally higher than SVM’s 94.48%. KNN-HHO outperforms KNNs with 94.73% accuracy compared to 93.14%. Both DT-HHO and DT achieve 94.73% accuracy, with DT-HHO exhibiting slightly better precision and recall. NB-HHO and NB show near-equivalent performance, with NB-HHO at 94.73% accuracy versus NB’s 94.6%. Overall, the optimized algorithms demonstrate consistent, albeit marginal, improvements over their classical versions.

A domain generalization network for imbalanced machinery fault diagnosis

Traditional models for Imbalanced Fault Diagnosis (IFD) face challenges in practical applications due to domain shifts caused by varying working conditions and machinery. Domain Generalization (DG) models provide an advantage over traditional approaches by learning class-discriminative and domain-invariant feature representations, allowing them to generalize to unseen target data. However, the scarcity of fault samples relative to healthy ones limits their application in real-world industrial scenarios. In this paper, we propose a Domain Mixed-Enhanced Domain Generalization Network (DEMDGN) that enhances IFD performance by utilizing mixup-based data augmentation and domain-based discrepancy metrics to align feature distributions across multiple heterogeneous source domains. By creating domain-invariant features, DEMDGN allows robust fault diagnosis under varying conditions. Extensive experiments on one marine machinery dataset and two bearing datasets demonstrate that the proposed method effectively addresses class imbalance and domain shift problems, achieving superior diagnostic performance.

The application of artificial intelligence in diabetic retinopathy: progress and prospects.

In recent years, artificial intelligence (AI), especially deep learning models, has increasingly been integrated into diagnosing and treating diabetic retinopathy (DR). From delving into the singular realm of ocular fundus photography to the gradual development of proteomics and other molecular approaches, from machine learning (ML) to deep learning (DL), the journey has seen a transition from a binary diagnosis of "presence or absence" to the capability of discerning the progression and severity of DR based on images from various stages of the disease course. Since the FDA approval of IDx-DR in 2018, a plethora of AI models has mushroomed, gradually gaining recognition through a myriad of clinical trials and validations. AI has greatly improved early DR detection, and we're nearing the use of AI in telemedicine to tackle medical resource shortages and health inequities in various areas. This comprehensive review meticulously analyzes the literature and clinical trials of recent years, highlighting key AI models for DR diagnosis and treatment, including their theoretical bases, features, applicability, and addressing current challenges like bias, transparency, and ethics. It also presents a prospective outlook on the future development in this domain.

A Unified Virtual Model for Real-Time Visualization and Diagnosis in Architectural Heritage Conservation

The aim of this paper is to propose a workflow for the real-time visualization of virtual environments that supports diagnostic tasks in heritage buildings. The approach integrates data from terrestrial laser scanning (3D point clouds and meshes), along with panoramic and thermal images, into a unified virtual model. Additionally, the methodology incorporates several post-processing stages designed to enhance the user experience in visualizing both the building and its associated damage. The methodology was tested on the Medieval Templar Church of Vera Cruz in Segovia, utilizing a combination of visible and infrared data, along with manually prepared damage maps. The project results demonstrate that the use of a hybrid digital model—combining 3D point clouds, polygonal meshes, and panoramic images—is highly effective for real-time rendering, providing detailed visualization while maintaining adaptability for mobile devices with limited computational power.