Aims and Objectives: To study pregnancy outcome in term patients with premature rupture of membranes (PROM) in whom labour was induced with oral misoprostol. Study Design: The study was a randomized prospective study of 150 cases of pregnant women with singleton pregnancies at and beyond 37 weeks of gestation with induction of laborwith oral misoprostol in PROM. Informed consent was taken. Materials and Methods: The study was carried out in the department of Obstetrics and Gynaecologyat a Tertiary care health institute. The study was a prospective study of 150 cases of pregnant women with singleton pregnancies with induction of labor with oral misoprostol in PROM. 150 cases of pregnant women with singleton pregnancies with PROM for induction of labor with oral misoprostol at and beyond 37 weeks of gestation were approached for the study. Study was approved by the ethics committee of the hospital. Informed consent was taken. The outcome was decided into primary and secondary outcome Primary outcome was measured as PROM-induction interval, PROM-delivery interval and induction to delivery interval. Secondary outcome was measured in terms of mode of delivery, number of doses of drug used, indication of cesarean section, maternal and neonatal complications, adverse effects of drugs like fever, diarrhoea, nausea and others, APGAR score of the neonate at 5 minute, NICU admission and neonatal infection. Results: Out of the studied patients 8% were in between age group of 18-20 years, 60%were between 2125 years, 28% were in between 26-30 years and 4% were more than30 years. Booked cases were 84% and unbooked cases were 16%. Out of these 60%cases were prima and 40% cases were multigravida. Gestational age wise 52% were in between gestational age of 37-39 weeks,28% were in between 39-40 weeks and 20%cases were having a gestational age of more than 40%. Out of these 1,2,3 and 4 doses of misoprostol were required in 20%,48%,20% and 12% respectively. Distribution of cases depending upon the doses of misoprostol required and mode of delivery and needfor instrumentation revealed that out of 102 cases requiring 1 or 2 doses of misoprostol only 2 patients required instrumentation while out of 39 cases requiring 3 or 4 doses of misoprostol 10 cases needed instrumentation. This was statistically significant. Analysis of misoprost ol doses required in relation with maternal complications revealed that