This article discusses the design, development, and usability assessment of a mobile system for producing hydrological predictions and sending flood warnings in response to the desire for human-centered technology to better the management of flood occurrences. Our work acts as a bibliographic reference for understanding what others have attempted and found, as well as gives an integrated set of recommendations. Furthermore, our guidelines offer guidance to aid in the design of mobile GIS-based hydrological models for mobile devices. We concentrate on the full design of a human–computer interaction framework for an effective flood prediction and warning system. In addition, we analyze and address the current user needs and requirements for building a user interface for mobile real-time flood forecasting in a methodical manner. Although a functional prototype was created, the primary objective of this research was to comprehend the complexity of possible users’ demands and actual use situations in order to solve the problem of comparable systems being difficult to use. After consulting with possible consumers, application design standards were established and implemented in the initial prototype. Focusing on user demands and attitudes, special consideration was given to the usability of the mobile interface. To develop the application, a variety of assessment methods are added. The conclusion of the examination was that the system is efficient and effective.