With the Internet of Things (IoT), mobile healthcare applications can now offer a variety of dimensionalities and online services. Disease Prediction Systems (DPS) increase the speed and accuracy of diagnosis, improving the quality of healthcare services. However, privacy is garnering an increasing amount of attention these days, especially concerning personal healthcare data, which are sensitive. There are a variety of prevailing privacy preservation techniques for disease prediction that are rendered. Nonetheless, there is a chance of medical users being affected by numerous disparate diseases. Therefore, it is vital to consider multi-label instances, which might decrease the accuracy. Thus, this paper proposes an efficient privacy-preserving (PP) scheme for patient healthcare data collected from IoT devices aimed at disease prediction in the modern Health Care System (HCS). The proposed system utilizes the Log of Round value-based Elliptic Curve Cryptography (LR-ECC) to enhance the security level during data transfer after the initial authentication phase. The authorized healthcare staff can securely download the patient data on the hospital side. Utilizing the Herding Genetic Algorithm-based Deep Learning Neural Network (EHGA-DLNN) can test these data with the trained system to predict the diseases. The experimental results demonstrate that the proposed approach improves prediction accuracy, privacy, and security compared to the existing methods.
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