MMAS-8 Scale Research Articles

Một số đặc điểm về tuân thủ sử dụng thuốc kháng động kinh của người bệnh động kinh tại Trung tâm Thần kinh Bệnh viện Bạch Mai

Epilepsy is a common disease, affecting about 65 million people in the world, accounting for 1% of the global burden of disease. Many aspects are affected such as: Economic, social and especially the quality of life. Some researches have shown that the quality of life of people with epilepsy is much lower than that of healthy people. Treatment of epilepsy is necessary. However, epilepsy treatment is difficult with a high rate of seizure recurrence. One of the important causes of seizure recurrence is the medication non-adherence that even making the disease more difficult to control. Objective: Describe the characteristics of medication adherence in epilepsy patients at the Bach Mai neurology center and analyze some related factors. Subjects and methods: Cross-sectional descriptive study on patients who were diagnosed and treated for outpatient epilepsy, came for follow-up examination at the neurology center of Bạch Mai hospital. Patient classification based on medication adherence characteristics and patients beliefs about drug use, through MMAS-8 scale and BMQ scale. Results: Out of 193 patients, 80.5% of them often had difficulty remembering to take medication, 11.4% felt bothered when adhering to treatment. 0% of patients achieved a high level of compliance, 27.5% at average level and 72.5% at low level). Conclusion: The majority of patients have a moderate level of knowledge about epilepsy, with most of them understanding that epilepsy can be cured, the available treatment methods, and the necessity of adhering to medication. However, they also recognize the serious issue of using stimulants. Despite this, none of the patients achieved a high level of adherence, with most showing low adherence to treatment, primarily due to occasionally forgetting to take their medication.

EFFECTS OF SOCIOECONOMIC AND CLINICAL FACTORS ON TREATMENT ADHERENCE IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASES PATIENT: FOCUS ON INHALATION THERAPY

Objective: Chronic obstructive pulmonary disease (COPD) refers to a persistent blockage of airflow that requires bronchodilator medication for the rest of one’s life. The goal of the treatment can only be met when the patient is adhering to the prescribed medicine. This study identifies and analyzes how clinical and socioeconomic factors affect COPD patients’ drug adherence to given therapy. The impact of our findings will reduce socioeconomic inequality in COPD management which will improve adherence to drugs and overall physical well-being. Methods: The hospital-based cross-sectional studies were conducted at the Department of TB and CD for 6 months in a tertiary care hospital. A total of 55 patients diagnosed with COPD participated in the study after signing the informed constant. The individual patients were interviewed using MMAS-8 and Kuppuswamy scale questionnaires. The data were analyzed by Chi-square test to determine the correlation between medication adherence and socioeconomic status in patients with COPD. Results: Among 55 COPD patients included in the study, their mean age was 62.2(+10.76) years. Out of the total participants: Significant associations between the medication adherence scale (MMRS-8) scores and the Kuppuswamy scale were found as p<0.0001, indicating that medication adherence was influenced by the patient’s socioeconomic status. In addition, the BORG scale which is used to measure exercise tolerance in COPD that found to have a significant correlation with an MMAS-8 score of p=0.03. Conclusion: Our study found that a person with low socioeconomic levels will have poor adherence to inhaler therapy, leading to poor health outcomes like exacerbation and low physical activity due to shortness of breath.

Assessment of Medication Adherence in Hypertensive Patients among Warangal Population

Background: Hypertension is the most common disease in India where 1 in 4 people suffering with it. In order to achieve the intended therapeutic outcomes, medication adherence is essential. Patients with hypertension must adhere to their disease by taking their prescriptions on time, following their diet, and making other lifestyle modifications. This study aims to assess medication adherence in Warangal population among hypertensive patients with comorbidities, social habits, medication use etc. Aims: The aim of the study is to assess the level of medication adherence and to investigate predictors of medication adherence and controlled hypertension in patients and to identify the factors enhancing medication adherence. The secondary aim is to describe the extent and type of medication used in patient population in Warangal. Study Design: An Observational, retrospective and cross - sectional study was employed to assess the predictors and level of medication adherence in hypertensive patients. Place and Duration of Study: Department of Cardiology, Sri Sri Cardiac Centre and Bhageerath Cardiac Care Centre, Hanamkonda, Warangal. The study was conducted from October 2022 to April 2023 for about a duration of 7 months. Methodology: This study includes 300 Hypertensive patients (Male - 169, Female 131) of age range between 20-90 years with various comorbidities like diabetes mellitus, coronary artery disease, hypothyroidism, dyslipidemia, COPD. We also included various sociodemographic factors like Gender, Age, Literacy, Income status, Alcohol consumption, Smoking status, Marital status, Controlled and Uncontrolled hypertension, usage of various drugs and Duration of hypertension. We observed Medication Adherence by using MMAS 8 scale. Results: Low levels of medication adherence among female patients (41%), educated patients (58%) compared to other groups because of awareness about their condition. Low adherence is noted in patients with low-income status ( 9.6% ), High adherence in nonsmokers (73.3%) and non-alcoholic (60.6%) compared to smokers (10.6%) and alcoholics (12.6%) and high adherence is reported in married (85%) category as compared to unmarried (2.6%), Patients with low comorbidities reported high adherence compared to patients with low comorbidities. High medication adherence is reported in uncontrolled blood pressure (50.3%) and in patients with \(\le\) year (24.6%) and 2-6 years (28%) of duration of hypertension. High adherence is noted with 2 combination therapy (23.6%), most of the participants are adherent to Telmisartan+ Metoprolol (25.2%) followed by Telmisartan+ hydrochlorothiazide (19.3%). According to MMAS-8 scale most of the patients reported (Q1) and (Q6), 91.3% of our study population were adherent to their medication, 7% were moderately adherent and 1.6% were low adherent to their medication. Conclusion: 91.3% of Medication adherence is noted in hypertensive patients in Warangal population. 8.6% of Medication Non-Adherence is noted and various factors for nonadherence were reported by patients. However various methods and apps should be developed to overcome the Medication Non-Adherence.

“A STUDY ON MEDICATION ADHERENCE AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS ATTENDING GOVERNMENT HEALTH CARE FACILITIES OF RAIPUR DISTRICT”

Introduction: Diabetes mellitus is a chronic progressive disorder characterized by high levels of blood glucose. Patient's role in medication adherence is inversely proportional to the severity & complication of diabetes. Adherence to medication is essential to obtain a therapeutic benet for diabetes. Hence, this study has been conducted to assess medication adherence among patients with type 2 diabetes mellitus attending government healthcare facilities of the Raipur district. To nd out the magnitude of Objective: adherence to prescribed medication among type 2 diabetic patients attending government health care facilities of Raipur district. Material And Method: A facility based cross-sectional study was conducted in government health care facilities selected by simple random sampling of Raipur district during November 2020 to November 2022. A total of 460 patients with more than 6 months duration of type-II Diabetes Mellitus were interviewed by using structured questionnaire after obtaining verbal consent from them. Medication adherence were assessed on Morisky medication adherence Scale (MMAS-8 scale) from the range of 0 to 8. If patients scored maximum 8 considered as high adherence, if patients scored 6-7 considered as moderate adherence, if patients scored of <6 considered as poor adherence. Out of 460 study subjects, it was Result: observed that about 21% were found highly adherent to medications, 28% moderately adherent and 51.1% were showing low adherence for diabetic medication. Overall medication adherence was very low in study s Conclusion: ubjects. It is clear that there is a serious need for healthcare professionals to address the problem of adherence to prescribed medications to individuals with diabetes mellitus

Treatment noncompliance level among patients with type 2 diabetes mellitus: A hospital based cross-sectional study in Bangladesh.

The consequence of good diabetic treatment depends on the patient’s commitment to a large degree. Noncompliance leads to inadequacy of metabolic control, which strengthens the advancement and speeds up diabetic complications. The study’s main goal was to assess the treatment noncompliance level among patients with type-2 diabetes mellitus (T2DM) in Bangladesh. This descriptive cross-sectional study was conducted at Medical Center Hospital, Chattogram, Bangladesh. The study included two hundred and fifty-nine patients with T2DM. Data regarding sociodemographic factors, patient’s characteristics, medication factors, physician-related factors, and noncompliance were collected using a pretested and structured questionnaire. Treatment adherence was assessed by Morisky Medication Adherence Scales (MMAS-8). Data analyses were conducted on SPSS v23.0 Software. The majority of the participants (56%) were in the 40–45 years of age group, followed by 32% in the older age group (≥60 years), and 62.5% of them were male. One hundred and sixty-eight (64.86%) patients were considered low adherent as per the response of the MMAS-8 scale (score <6), followed by 57 (22.0%) patients were regarded as high adherent (score 8) and 34 (13.13%) patients were considered medium adherent (score 6–7) to treatment. Observing the frequency distribution for noncompliance, financial concerns (32.3%), forgetfulness (27.7%), a busy daily schedule (17.7%), and fear of antihyperglycemic drug side effects were all identified as significant explanations. On multivariate analysis, participants aged 60 years or more, monthly family incomes of <30,000BDT or 30,000–50,000 BDT, smoking, and uncontrolled glycemic status showed higher chances of noncompliance than their counterparts. Patient counseling and awareness programs may enhance treatment adherence among people with T2DM. Our findings will help physicians and public health workers to develop targeted strategies to increase awareness of the same among their patients.

Reliability and validity of the Chinese version of the eight-item Morisky Medication Adherence Scale in Chinese patients with systemic lupus erythematosus.

To evaluate the reliability and validity of the Chinese version of the eight-item Morisky Medication Adherence Scale (MMAS-8) in Chinese patients with systemic lupus erythematosus (SLE). The survey was conducted with a consecutive sampling of 158 Chinese SLE patients attending public hospitals from January to March 2021. We used the translated Chinese version of the MMAS-8 to collect related data. Reliability, item, and factor analyses were used to test the reliability and validity of the MMAS-8 scale in the selected patients. The internal consistency reliability was evaluated using Cronbach's α coefficient. Test-retest reliability was assessed using intraclass correlation coefficients (ICCs) in a subset of 30 participants. Construct validity was evaluated using confirmatory factor analysis and correlations between the Self-efficacy for Appropriate Medication Use Scale (SEAMS) and related measures. The internal consistency reliability of the Chinese version of the MMAS-8 was high (Cronbach's α = 0.817), and the test-retest reliability was excellent (intraclass correlation = 0.947; P < 0.001). There were significant differences in the F test and t test between the two extreme groups before and after the ranking of 27% of the questionnaire scores (P < 0.001). The Kaiser-Meyer-Olkin (KMO) value of construct validity was 0.860. The spherical test value of Bartlettgers was 417.8822. Factor analysis yielded three components that accounted for 69.375% of the total variance. Exploratory factor analysis identified three dimensions of the Chinese version of the MMAS-8. In terms of criterion validity, the correlation of the MMAS-8 score in SEAMS indicated that the convergent validity was good (r = 0.926; P < 0.001). This study shows that the Chinese version of the Medication Adherence Scale-8 is a reliable and valid tool for assessing medication adherence in Chinese SLE patients. Key Points • Many factors affect medication adherence in SLE patients. • Many questionnaires measure medication adherence levels. • There is a lack of reliable validation of medication adherence questionnaires specifically for SLE patients.

N03 Medication adherence in relation to Health-related Quality of Life in patients with Inflammatory Bowel Disease – A cross-sectional study

Abstract Background Inflammatory Bowel Diseases are chronic diseases often with complex treatment. The treatment is lifelong and complex and may include several different pharmaceutical groups and sometimes surgery. Not rarely is treatment resistance developed and the treatment may come with different degrees of side effects. Earlier research has shown insufficient to medication adherence and a lower degree of health-related quality of life in patients with inflammatory bowel disease. The aim is to describe the relationship between medication adherence and health-related quality of life in a Swedish population diagnosed with inflammatory bowel disease. Additional research questions are if any risk factors of low medication adherence can be identified from the collected variables. Methods This cross-sectional study included N=206 patients from three different regions in Sweden. The questionnaires MMAS-8 and Short Health Scale were used combined with a questionnaire regarding patient characteristics. The data and patient characteristics were described and analyzed using descriptive statistics. Ethical approval has been received from the Regional Ethical Review Board, Linköping, Sweden (no.: 2015/369-31). Results The majority of patients had Ulcerative Colitis (62.6%) There were no significant differences between the different groups of Inflammatory Bowel Disease regarding patient characteristics apart from having gone through surgical procedures, which were more common in patients with Crohn’s disease. A small correlation was shown between medication adherence and the health-related quality of life dimension social function (rho = -0.146; p &amp;lt;0.05). Medication adherence showed no significant correlations to the remaining health-related quality of life dimensions: disease related worry, symptom burden and sense of general well-being. Possible risk factors identified for low medication adherence were age between 30 and 50, working at high occupational level, and higher educational level. Conclusion The complexity of measuring medication adherence has been established, making it difficult to make any certain conclusions regarding the hypothesis in this report. This study showed no clear association between medication adherence and health-related quality of life in patients with inflammatory bowel disease. However, it visualized the need of optimizing the instruments used to measure medication adherence in individuals with a non-conventional treatment plan

Exploring of Determinants Factors of Anti-Diabetic Medication Adherence in Several Regions of Asia - A Systematic Review.

BackgroundThe determinants of medication adherence in people with diabetes may differ between populations of an area due to social environment, cultural beliefs, socioeconomic conditions, education, and many other factors differences.ObjectiveTherefore, this study aims to explore, identify and classify the determinants of medication adherence in several Asian regions.MethodsA systematic literature review was conducted to gain insight into the determinants of medication adherence. Seven relevant databases (EBSCO, ProQuest, PubMed, ScienceDirect, Scopus, Wiley, dan Taylor and Francis) and hand searching methods were conducted from January 2011 to December 2020. Keywords were compiled based on the PICO method. The selection process used the PRISMA guidelines based on inclusion, and the quality was assessed using Crowe’s critical assessment tool. Textual summaries and a conceptual framework model of medication adherence were proposed to aid in the understanding of the factors influencing medication adherence.ResultsTwenty-six articles from countries in several Asian regions were further analyzed. Most studies on type 2 diabetes patients in India used the MMAS-8 scale, and cross-sectional study is the most frequently used research design. The medication adherence rate among diabetic patients was low to moderate. Fifty-one specific factors identified were further categorized into twenty-three subdomains and six domains. Furthermore, the determinants were classified into four categories: inconsistent factors, positively related factors, negatively related factors, and non-associated factors. In most studies, patient-related factors dominate the association with medication adherence. This domain relates to patient-specific demographics, physiological feelings, knowledge, perceptions and beliefs, comorbidities, and other factors related to the patient. Several limitations in this review need to be considered for further research.ConclusionMedication adherence to diabetic therapy is a complex phenomenon. Most determinants produced disparate findings in terms of statistical significance. The identified factors can serve various goals related to medication adherence. Policymakers and health care providers should consider patient-related factors.

Assessing the Medication Adherence of Metabolic Disorders in South India

Aim: The study's main objective was to assess patients' adherence towards treatment and daily practices among Hypertension (HT), Diabetes Mellitus (DM) Type II and hypothyroid participants in South India before and after providing counseling and education based on WHO standards.&#x0D; Study Design: The present study is a prospective open-labeled observational study.&#x0D; Place and Duration of the Study: The present study was conducted in Vijayawada, South India for six months.&#x0D; Methodology: A total of 490 participants with Hypertension, Diabetes Mellitus (Type II) and Hypothyroidism were assessed for adherence based on the Morisky medication adherence scale containing 8 points at the starting of the study and 6 months after providing counseling and education.&#x0D; Results: At the initial point of study, only 12% of the Hypertensive group, 17% of Diabetes Mellitus (Type II) and 15% Hypothyroid group have high adherence. Towards the completion of the study, around 41% in the Hypertensive group, 50% of Diabetes Mellitus (Type II) and 60% Hypothyroid group had high adherence.&#x0D; Conclusion: The adherence was low at the initial point of the study among all the three groups. After counseling and education provided through the World Health Organization (WHO) specified criteria, we have seen a good increase in the adherence, measured with the MMAS-8 scale. Greater efforts should be made in educating and counseling the patients suffering from such chronic illnesses to improve their quality of life.

The influence of reminder book to adherence of heart failure patients in Malang city.

Background: Non-adherence to the recommended therapy causes patients with heart failure to experience recurrence of the disease. Reminder book on therapy adherence is very useful, because it assists in monitoring adherence to therapy carried out by patients while at home. Therefore, this study aims to determine the effect of the existence of a reminder book on adherence to therapy among patients with heart failure in a private hospital in Malang.Design and Methods: A pre-experiment design with one-group pre and posttest was used. The respondents were 18 patients that received counseling on the management of heart failure therapy while at home and were given a reminder book. Furthermore, the modified MMAS-8 scale was the study instrument used to measure adherence.Result: The results showed that most respondents were above the age of 65 with a treatment duration of 1 to 5 years. It was discovered that most of the respondents had never received information about heart failure therapy. Data analysis which was carried out using the Wilcoxon test with a p-value of 0.001, showed that there was a significant difference between respondents’ compliance before and after being given a reminder book.Conclusions: From this study, it was concluded that providing a reminder book has an effect on therapeutic adherence in patients with heart failure. Researchers recommend that hospitals should make use of this reminder as a tool to control or supervise outpatient therapy.Significance for public healthThe number of patients diagnosed with heart failure is increasing yearly, including rehospitalization rates. Adherence to therapy among patients with heart failure is important in preventing recurrence. One of the ways in improving adherence is the use of self-management techniques, such as independent monitor therapy. An example of this therapy is the use of a reminder book which helps to improve adherence and self-efficacy in patients with heart failure.

Effect of Flyers on Knowledge and Adherence to Medication of Hypertensive Patients

Knowledge and adherence to taking medication in patients with hypertension is very important because knowing and adhering in taking antihypertensive drugs can control the blood pressure of people with hypertension. The purpose of this study was to determine the effect of giving flyers on knowledge and adherence to taking medication for hypertensive patients. The method used in this research is a quasi-experimental method, with a non-randomized control group pretest and posttest design which was carried out on 96 respondents with purposive sampling technique. Collecting data for knowledge using the knowledge questionnaire, and adherence using the MMAS-8 scale. Data were analyzed using Wilcoxon test and Mann-Whitney test. The results of the study on hypertensive patients showed that giving flyers had a significant effect on knowledge with a p value = 0.000 and on patient adherence with a p value = 0.000.

Effect of Nursing Quality Management on the Nosocomial Infection Rate and Psychology State of Patients with Burn and Plastic Surgery.

Background:To explore the effect of nursing quality management on the nosocomial infection rate and Psychology State of patients with burn and plastic surgery.Methods:Overall, 92 patients with burn and plastic surgery admitted to Qilu Hospital, Jinan, China from Apr 2017 to Jul 2018 were selected, in which 46 cases were randomly selected as a control group for routine nursing management, and another 46 cases as a research group to strengthen nursing quality management. The incidence of nosocomial infection, nursing satisfaction and nurse-patient disputes were compared. MMAS-8 scale was used to compare the compliance of the two groups. SAS and SDS score were used to compare the psychological status. The recovery and discharge were compared.Results:The incidence of nosocomial infection in the study group was significantly lower than that in the control group (P<0.05). The total satisfaction rate of the study group was significantly higher than that of the control group (P<0.05). The incidence of nurses-patients disputes was significantly lower than that of the control group. The SAS and SDS score of the study group were significantly better than the control group (P<0.05). The healing time, blood circulation recovery time of skin wounds and discharge time in the study group were significantly better than those in the control group.Conclusion:Strengthening nursing quality management can effectively reduce the nosocomial infection rate of burn and plastic surgery. It helps to further accelerate the recovery of patients and make patients ’psychological state better.

Assessing Oral Medication Adherence and Identifying Predictors of Low Adherence in Chinese Inflammatory Bowel Disease Patients.

BackgroundPoor medication adherence in inflammatory bowel disease (IBD) had a negative impact on disease outcomes. In this study, we aimed to determine predictors of low adherence in the Chinese IBD populations and also aimed to compare a self-reported scale to a pharmacy refill index in assessing adherence of 5-ASA and azathioprine taken by Chinese IBD patients.Patients and MethodsAdult patients with IBD who had been taking 5-ASA or azathioprine for at least 3 months were recruited from hospital outpatient clinics. The MPR was calculated from previous six-month pharmacy refill data and the self-reported Morisky Medication Adherence Scale (MMAS-8) was issued through QR code questionnaires. Intentional and unintentional adherence scores were calculated according to specific items. Non-adherence was defined as MMAS-8 scores <6 or MPR < 0.8.ResultsThe response rate in the IBD patients was as high as 97%. 5-ASA non-adherence rate assessed by MPR was 30% and 37% by MMAS-8, and azathioprine non-adherence rate assessed was 33% by both MPR and MMAS-8. In a linear regression analysis, MPR value was significantly correlated with MMAS-8 score in 5-ASA group (r=0.4, p=0.003), and significantly correlated with unintentional adherence score (r=0.47, p<0.001). No significant correlation was observed between MPR value and MMAS-8 score in azathioprine group. Multivariate analysis demonstrated that age (OR: 1.08; 95% CI: 1.02–1.13; P=0.0015) and previous abdominal surgery (OR: 3.18; 95% CI: 2.09–4.27; P=0.04) were associated with high medication adherence. While patients who had small intestine lesion (OR: 0.09; 95% CI: 0.01–0.17; P=0.006) were associated with low adherence.ConclusionPredictors of low adherence were young age, lesions on small intestine, whereas previous abdominal surgery was a protective factor. This study also demonstrated that the MMAS-8 scale was a valid instrument for assessing 5-ASA adherence in IBD patients. Unintentional non-adherence was significantly related to the total non-adherence, which would allow to use the tool to seek ways for adherence improvement.

Corrigendum and Editorial Warning Regarding Use of the MMAS-8 Scale (A Remote Medication Monitoring System for Chronic Heart Failure Patients to Reduce Readmissions: A Two-Arm Randomized Pilot Study).

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Retracted: Using the Healthy Days Measure to Assess Factors Associated with Poor Health-Related Quality of Life for Patients with Metastatic Breast, Lung, or Colorectal Cancer Enrolled in a Medicare Advantage Health Plan.

The article entitled, "Using the Healthy Days Measure to Assess Factors Associated with Poor Health-Related Quality of Life for Patients with Metastatic Breast, Lung, or Colorectal Cancer Enrolled in a Medicare Advantage Health Plan," by Casebeer AW et al, which published online ahead of print in Population Health Management [doi: 10.1089/pop.2018.0024], is being retracted by the authors so that they can remove references to the 8-item Morisky Medication Adherence Scale (MMAS-8) and republish the article without such references. Dr. Casebeer's team obtained a license to use the MMAS-8 scale from Dr. Morisky prior to conducting the study. Nevertheless, after publication of a separate article in the Journal of Patient-Reported Outcomes that also cited the MMAS-8, as the lead author, Dr. Casebeer was contacted by Dr. Morisky who requested that a number of changes be made to the article. Dr. Casebeer and her team have no desire to engage in a dispute with Dr. Morisky and therefore proactively contacted the Editor of Population Health Management and requested that the scale be removed from her published paper. After assessing all of the provided information, the Editor agreed to the authors' request. It is important to note that the retraction of Dr. Casebeer's article is not the result of any misconduct on her part or that of her team. The retraction serves to remove the published version of the article that contains the MMAS-8 scale and a revised version that does not contain the tool or any references to it will be published. The elimination of the scale does not alter the results or conclusions of the study. Population Health Management is committed to upholding the highest standards of peer review and the community it serves.

Validation of the Sinhala version of the Morisky Medication Adherence Scale to determine medication adherence in patients with bipolar affective disorder on lithium therapy

Rationale, aims and objectives: The Morisky Medication Adherence Scale (MMAS-8) is a self-reported scale used in assessing medication adherence in patients on chronic therapy. Medication adherence is a neglected area of research in Sri Lanka and in this study we have attempted to validate the Sinhala translation of the MMAS-8 to determine medication adherence among patients stabilized on lithium therapy for bipolar disorder (BD).Methods: The MMAS-8 was translated to Sinhala with standard forward and backward translations from English to Sinhala. Patients with BD on stable doses of lithium were administered the Sinhala version of the MMAS-8. During the same visit, the serum lithium concentration was measured. Criterion validity was assessed using therapeutic serum lithium concentrations as the gold standard. Internal consistency was assessed using Cronbach’s alpha and Spearman’s rank correlation was used to assess test-retest reliability.Results: From a sample of 240 patients, 82.1% were considered adherent, with serum lithium concentration &gt;0.4 mmol/L. The mean MMAS-8 score was 6.95±1.3. According to the MMAS-8 scale, 13.3% reported low adherence while 43.3% reported medium and high adherence equally using MMAS cut offs &lt;6, 6 to&lt;8 and 8 respectively. The scale sensitivity to identify adherence at a cut-off score of 6 was 86.3%. The test–retest reliability value was 0.708 (p&lt;0.001). Internal consistency was found with a Cronbach’s alpha value of 0.608 for the 8 items of the scale.Conclusion: The Sinhala version of MMAS-8 can be used as a sensitive instrument to identify medication adherence in patients with bipolar disorders.

Retraction of: Dayer et al., J Palliat Med 2016;19(5):538–541; DOI: 10.1089/jpm.2015.0230

Journal of Palliative MedicineVol. 21, No. 2 Retraction NoticeFree AccessRetraction of: Dayer et al., J Palliat Med 2016;19(5):538–541; DOI: 10.1089/jpm.2015.0230This article retracts the following:A Palliative Care Clinic's Experience with Medication Adherence to Neuropathic Pain MedicationsPublished Online:1 Feb 2018https://doi.org/10.1089/jpm.2015.0230.retractAboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail The Brief Report article entitled, “Adherence to Adjuvant Neuropathic Pain Medications in a Palliative Care Clinic,” by Lindsey Dayer, Sarah Harrington, and Bradley Martin in the May 2016 issue of Journal of Palliative Medicine (JPM), [19(5): 538 – 541; DOI: 10.1089/jpm.2015.0230] requires a retraction due to a legal dispute regarding the eight-item Morisky Medication Adherence Scale (MMAS-8) which was adapted for use in the article.Dr. Dayer's article appropriately cited the original article in which the MMAS-8 scale appeared, and the original MMAS-8 article notes that the development of the scale was supported with federal funds. However, after publication of her article, Dr. Dayer was notified by Dr. Morisky's legal counsel that Dr. Morisky asserted a copyright interest in the MMAS-8 scale, and that its reuse required both a substantial royalty payment and the licensed use of an electronic grading system developed by Dr. Morisky. Dr. Dayer and her institution dispute the validity and reasonableness of Dr. Morisky's demands in light of the National Institutes of Health's Principles and Guidelines for Recipients of NIH Research Grants and Contracts on Obtaining and Disseminating Biomedical Research Resources, 64 Fed. Reg. 72,090 (Dec. 23, 1999). As a result of Dr. Morisky's demands, Dr. Dayer contacted the Editor of JPM and requested that the scale be removed from her published paper. The Editor agreed.It is important to note that the retraction of Dr. Dayer's article is not the result of any misconduct on her part or that of her team. The retraction serves to remove the published version of the article that contains the MMAS-8 scale, and replace it with a revised version that does not contain the tool or any references to it. The elimination of the scale does not alter the conclusions of the study.Journal of Palliative Medicine is committed to the highest standards of peer review and the community it serves.FiguresReferencesRelatedDetailsRelated articlesA Palliative Care Clinic's Experience with Medication Adherence to Neuropathic Pain Medications1 Feb 2018Journal of Palliative Medicine Volume 21Issue 2Feb 2018 InformationCopyright 2018, Mary Ann Liebert, Inc.To cite this article:Retraction of: Dayer et al., J Palliat Med 2016;19(5):538–541; DOI: 10.1089/jpm.2015.0230.Journal of Palliative Medicine.Feb 2018.273-273.http://doi.org/10.1089/jpm.2015.0230.retractPublished in Volume: 21 Issue 2: February 1, 2018PDF download

How can we improve medical adherence to intranasal corticosteroids in children?

ObjectiveTo evaluate the factors which may be related to nonadherence to intranasal corticosteroids (ICS) in the treatment of allergic rhinitis (AR) in children. MethodsA prospective study was conducted on children with AR diagnosis in a tertiary referral hospital. All participants were provided with mometasone furoate nasal sprays for 30 days after the diagnosis. Caregivers were called back when the therapy was over and completed a questionnaire about the factors that may influence the adherence to the treatment. Afterwards each caregiver completed the Turkish language validated Morisky Medical Adherence Scale (MMAS-8) form. Each factor was evaluated according to MMAS-8 score and all variables were analyzed statistically. ResultsA total number of 76 children with a mean age of 7.82 years were included in the study. The mean overall MMAS-8 score was 2.80. There was only one factor significantly related to low adherence; the number of dependent children to the caregiver (p = 0.011). Besides this 71.51% of the answers to MMAS-8 scale were compatible with good adherence. ConclusionThe clinician must consider the factors which may lead to non-adherence while setting up a treatment plan. The demographic and sociocultural factors must be taken into consideration and treatment schedule should be made in respect of daily activities of the children. Moreover the father can be involved in the therapy plan and back up the mother as they are usually the responsible parent for children's medical therapy.

Validación de la escala de Morisky de 8 ítems en pacientes con enfermedad renal crónica.

Introducción: Es importante proveer un adecuado y oportuno manejo a largo plazo de la ERC, por medio de estrategias farmacológicas y no farmacológicas, sin embargo, la baja adherencia de los pacientes al tratamiento farmacológico pone en riesgo la efectividad de la intervención.Objetivo: Traducir al español, validar y adaptar la escala de adherencia al tratamiento de Morisky de 8 items a pacientes con ERC.Materiales y Métodos: La traducción del MMAS-8 se realizó de acuerdo con las directrices para la traducción y la adaptación de instrumentos de medida para ser utilizados en investigación médica, se validó mediante juicio de expertos siguiendo el método Delphi. Se realizó un estudio piloto corte transversal, donde se encuesto a 30 pacientes que acudieron a consulta de predialisis de la unidad renal del hospital militar central en Bogotá Colombia.Resultados: La escala MMAS-8 traducida al español fue sometida a los jueces para su validación obteniéndose un porcentaje de acuerdo igual o mayor al 80% para todas las preguntas, se calculó el coeficiente de concordancia W de Kendall que en este caso fue 0,8 con un p valor de 0,0001 y se interpretó como un alto grado de concordancia entre las valoraciones hechas por los jueces a los diferentes ítems del cuestionario. Se aplicó el MMAS-8 a 30 pacientes con una media de edad de 75,9 años (+/- 15), el nivel de adherencia al tratamiento se analizó según el puntaje de la escala de Morisky de 8 items, clasificándose como baja adherencia al tratamiento en el 62,5% de los casos con puntaje menor de 6, mediana adherencia 28,1% de los pacientes puntaje entre 6 y 7 y alta adherencia solo el 9,4% de los pacientes con puntaje mayor de 8.Conclusiones: La escala de medición de adherencia al tratamiento de Morisky de 8 items es válida para medir la adherencia al tratamiento farmacológico de pacientes con enfermedad renal crónica según juicio de expertos.

Treatment adherence and beliefs about medicines among Egyptian vitiligo patients.

The MMAS-8 scale and BMQ had good internal consistency (Cronbach's α = 0.78 and 0.66, respectively). Using Morisky's recommended cutoff point, 71% of patients were categorized as low or nonadherent to the scheduled therapy. Patients who perceived specific necessity of dermatological medicines significantly adhered to their therapy (OR 1.23; 95% CI 1.09, 1.38; p = 0.001) whereas patients who had specific concerns about the adverse effects exhibited significant low adherence (OR 0.65; 95% CI 0.56, 0.76; p < 0.001). Positive beliefs about the necessity of medications in vitiligo do not necessarily reflect high adherence. Patients' adherence behavior is a multidimensional and dynamic process. The prolonged course of treatment, its cost, and unsatisfactory outcomes influenced the patients' adherence.