Mixture Of Glycerol Research Articles

Direct determination of chlorine in the glycerin by-product of biodiesel production: A green approach using energy dispersive X-ray fluorescence spectrometry

Glycerin, by-product of biodiesel, is produced in large amounts and it contains several contaminants, including chorine (due to the neutralization stage using HCl). When using this glycerin as biomass to produce energy, the presence of alkaline chlorides may lead to the formation of corrosive fumes at high temperatures. In this sense, the knowledge of chloride content is important in order to decide the fate of this raw by-product. The direct spectrometric determination of chlorine is an analytical challenge. In this context, energy-dispersive X-ray fluorescence spectrometry provided direct and accurate determination, relying on external calibration based on sample dilution and matrix matching with mixture of pure glycerin and water and using NaCl as the analytical (primary) standard. Method limit of quantification was 50 mg kg−1, with analytical curve up to 1000 mg kg−1 (R2 = 0.9992), and repeatability below 5% were found to be adequate for such application in such highly salty samples (original concentrations at mg g−1). In addition to sample directly analysis, without any previous treatment but homogenization and dilution, not requiring chemical derivatization and the not using of toxic reagents are in consonance to the analytical green chemistry requirements, allowing direct analysis of sample with no chemical derivatization with toxic reagents.

Development and economic evaluation of a CPVT system with PHP cooling; An experimental study

In this paper, the experimental investigation of the performance of a concentrated hybrid photovoltaic thermal solar system is sought. Accordingly, there is a parabolic trough concentrator receiver that consists of three components: a triangular duct, photovoltaic cells covering the duct, and a three-turn PHP. The PHP cools down the photovoltaic cells efficiently and regenerates waste heat. The duct is filled with a heat transfer fluid surrounding the PHP’s evaporator. The condensation section of the PHP is located outside the solar concentrator. Using a one-axis polar mechanism, the concentrator tracks the sun from east to west. The system experiment setup was fabricated and tested outdoors in Tehran’s climate. Different heat transfer fluids, including Glycerine, Ethylene Glycol, and Calcium Chloride water mixture, were tested. Given the enhancement of PHP performance, a variety of working fluids were tested, including graphene oxide nanofluid/water, acetone, and pure water. The experiments showed that graphene oxide nanofluid/water mixture provided the highest thermal performance. With the use of graphene oxide nanofluid/water (as a working fluid) and glycerine (as heat transfer fluid), experiment results showed a decrease of 7.84 °C in PV temperature and a consequent increase of 21.85% in electrical efficiency in best condition. Furthermore, the provided cooling system recycles a maximum of is 190.4 kJ of thermal energy equivalent 52.5% thermal efficiency, increasing overall efficiency by 74.35%. Lastly, the IRR of 65.41%, PBT of 1.04 years, and LCOE of 1.84 $/kWh demonstrate appropriate financial profitability.

The Role of the Interface of PLA with Thermoplastic Starch in the Nonisothermal Crystallization Behavior of PLA in PLA/Thermoplastic Starch/SiO2 Composites

Corn starch was plasticized by glycerol suspension in a twin-screw extruder, in which the glycerol suspension was the pre-dispersion mixture of glycerol with nano-SiO2. Polylactide (PLA)/thermoplastic starch/SiO2 composites were obtained through melt-blending of PLA with thermoplastic starch/SiO2 in a twin-screw extruder. The nonisothermal crystallization behavior of PLA in the composites was investigated by differential scanning calorimetry. An interface of PLA with thermoplastic starch was proven to exist in the composites, and its interfacial bonding characteristics were analyzed. The interfacial binding energy stemming from PLA with thermoplastic starch exerts a significant influence on the segmental mobility of PLA at the interface. The segmental mobility of PLA is gradually improved by increasing interfacial binding energy, and consequently, the relative crystallinity on the interface exhibits progressive promotion. The Jeziorny model could well describe the primary crystallization of PLA in the composites. The extracted Avrami exponents based on the Jeziorny model indicate that the primary crystallization of PLA follows heterogeneous nucleation and three-dimensional growth. This study has revealed the intrinsic effect of the interfacial segmental mobility on the nonisothermal crystallization behavior of PLA in composites, which is of technological significance for its blow molding.

Homemade BIOPLASTICS (Biodegradable Plastic From Cassava Peel Waste) with Analysis of the Effect of Glycerol and Cellulose Ratio on Tensile Strength, Elongation, and Thickness

The massive use of plastic as food and non-food packaging does not cause a few problems. The accumulation of plastic waste can cause environmental pollution, both water and soil pollution, because plastic will be damaged and decomposed within 300 to 500 years. For this reason, environmentally friendly plastics are needed for conventional plastics which of course have characteristics that are not far inferior to conventional plastics such as flexible, lightweight, not easy to break, waterproof, not corrosive. Bioplastic is a type of plastic that can be degraded so it is not harmful to the environment. This paper aims to see the effect of the ratio of glycerol and cellulose on tensile strength, elongation, and thickness of bioplastics using cassava peel waste. This research uses cassava peel as the basic material for making starch which is then given a mixture of glycerol and cellulose to be used as bioplastics. Tensile strength and elongation tests were carried out using the zwick/roell Universal Testing Machine (UTM). While the thickness uses Mitutoyo's Thickness Gauge. The results obtained are thin plastic sheets made using 5 grams of starch with a mixture of cellulose (0.4; 0.6; 0.8) grams and glycerol (100%, 150%, 200%) ml which have been tested for mechanical properties. The best mechanical properties of the tensile strength of bioplastics were indicated by the sample coded C2G2 with a concentration of 1.5 ml of glycerol and 0.8 gram of cellulose with an average tensile strength of 7.4808 (N/mm2), while the highest elongation was shown in the sample coded C3G3. with a concentration of 2.0 ml of glycerol and 0.8 grams of cellulose with an average sample elongation value of 6.2448%, while the highest thickness determined in the sample coded C2G2, a concentration of 1.5 ml of glycerol and 0.6 grams of cellulose with a value of the average thickness is 269,066 (µm).

Effect of Solvent on Convectively Driven Silica Particle Assembly: Decoupling Surface Tension, Viscosity, and Evaporation Rate

The process of convectively self-assembling particles in films suffers from low reproducibility due to its high dependency on particle concentration, as well as a variety of interactions and physical parameters. Inhomogeneities in flow rates and instabilities at the air-liquid interface are mostly responsible for reproducibility issues. These problems are aggravated by adding multiple components to the dispersion, such as binary solvent mixtures or surfactant/polymer additives, both common approaches to control stick-slip behavior. When an additive is used, not only does it change the surface tension, but also the viscosity and the evaporation rate. Worse yet, gradients in these three properties can form, which then lead to Marangoni currents. Here, we use a series of alcohols to study the role of viscosity independently of other solvent properties, to show its impact on stick-slip behavior and interband distances. We show that mixtures of glycerol and alcohol or poly(acrylic acid) and alcohol lead to more complex patterning. Marangoni currents are not always observed in co-solvent systems, being dependent on the rate of solvent evaporation. To produce homogeneous particle assemblies and control stick-slip behavior, gradients must be avoided, and the surface tension and viscosity need both be carefully controlled.

Aerosolized nicotine from e-cigarettes alters gene expression, increases lung protein permeability, and impairs viral clearance in murine influenza infection.

E-cigarette use has rapidly increased as an alternative means of nicotine delivery by heated aerosolization. Recent studies demonstrate nicotine-containing e-cigarette aerosols can have immunosuppressive and pro-inflammatory effects, but it remains unclear how e-cigarettes and the constituents of e-liquids may impact acute lung injury and the development of acute respiratory distress syndrome caused by viral pneumonia. Therefore, in these studies, mice were exposed one hour per day over nine consecutive days to aerosol generated by the clinically-relevant tank-style Aspire Nautilus aerosolizing e-liquid containing a mixture of vegetable glycerin and propylene glycol (VG/PG) with or without nicotine. Exposure to the nicotine-containing aerosol resulted in clinically-relevant levels of plasma cotinine, a nicotine-derived metabolite, and an increase in the pro-inflammatory cytokines IL-17A, CXCL1, and MCP-1 in the distal airspaces. Following the e-cigarette exposure, mice were intranasally inoculated with influenza A virus (H1N1 PR8 strain). Exposure to aerosols generated from VG/PG with and without nicotine caused greater influenza-induced production in the distal airspaces of the pro-inflammatory cytokines IFN-γ, TNFα, IL-1β, IL-6, IL-17A, and MCP-1 at 7 days post inoculation (dpi). Compared to the aerosolized carrier VG/PG, in mice exposed to aerosolized nicotine there was a significantly lower amount of Mucin 5 subtype AC (MUC5AC) in the distal airspaces and significantly higher lung permeability to protein and viral load in lungs at 7 dpi with influenza. Additionally, nicotine caused relative downregulation of genes associated with ciliary function and fluid clearance and an increased expression of pro-inflammatory pathways at 7 dpi. These results show that (1) the e-liquid carrier VG/PG increases the pro-inflammatory immune responses to viral pneumonia and that (2) nicotine in an e-cigarette aerosol alters the transcriptomic response to pathogens, blunts host defense mechanisms, increases lung barrier permeability, and reduces viral clearance during influenza infection. In conclusion, acute exposure to aerosolized nicotine can impair clearance of viral infection and exacerbate lung injury, findings that have implications for the regulation of e-cigarette products.

Enhanced glycerol assimilation and lipid production in Rhodotorula toruloides CBS14 upon addition of hemicellulose primarily correlates with early transcription of energy-metabolism-related genes

BackgroundLipid formation from glycerol was previously found to be activated in Rhodotorula toruloides when the yeast was cultivated in a mixture of crude glycerol (CG) and hemicellulose hydrolysate (CGHH) compared to CG as the only carbon source. RNA samples from R. toruloides CBS14 cell cultures grown on either CG or CGHH were collected at different timepoints of cultivation, and a differential gene expression analysis was performed between cells grown at a similar physiological situation.ResultsWe observed enhanced transcription of genes involved in oxidative phosphorylation and enzymes localized in mitochondria in CGHH compared to CG. Genes involved in protein turnover, including those encoding ribosomal proteins, translation elongation factors, and genes involved in building the proteasome also showed an enhanced transcription in CGHH compared to CG. At 10 h cultivation, another group of activated genes in CGHH was involved in β-oxidation, handling oxidative stress and degradation of xylose and aromatic compounds. Potential bypasses of the standard GUT1 and GUT2-glycerol assimilation pathway were also expressed and upregulated in CGHH 10 h. When the additional carbon sources from HH were completely consumed, at CGHH 36 h, their transcription decreased and NAD+-dependent glycerol-3-phosphate dehydrogenase was upregulated compared to CG 60 h, generating NADH instead of NADPH with glycerol catabolism. TPI1 was upregulated in CGHH compared to cells grown on CG in all physiological situations, potentially channeling the DHAP formed through glycerol catabolism into glycolysis. The highest number of upregulated genes encoding glycolytic enzymes was found after 36 h in CGHH, when all additional carbon sources were already consumed.ConclusionsWe suspect that the physiological reason for the accelerated glycerol assimilation and faster lipid production, was primarily the activation of enzymes that provide energy.

Structure optimization of a liquid-sealed SNS fiber optic temperature sensor

For the advancement of temperature monitoring devices, research into high sensitivity fiber optic temperature sensors is valuable. This research suggests a fiber optic temperature sensor with great sensitivity. Specifically, the NCF (no core fiber) spliced with various diameters is employed within the multimode interference region of the typical SNS (single mode fiber-no core fiber-single mode fiber) sensor. The morphology of the splice sites connecting two NCFs is also regulated by fusing. The mixture of ethanol and glycerol is used to coat the entire structure. According to the experimental results, the proposed sensor can achieve a temperature sensitivity of −14.448 nm/°C. Additionally, the sensor has good performance in repeatability and temperature cycling thanks to its simple, dependable structure. It is anticipated that the relevant results will be useful for the development and applications of precise temperature measurement.

Partial Vapor Pressures, Activity Coefficients, Henry Volatility, and Infinite Dilution Activity Coefficients of Nicotine from Binary Mixtures with Glycerol and with 1,2-Propanediol at 298.15 K.

The equilibrium headspace concentration of nicotine in nitrogen gas was measured by gas chromatography for binary mixtures of nicotine with glycerol and with 1,2-propanediol at temperatures near 298.15 K. The storage temperature ranged from 296.25 to 298.25 K. The nicotine mole fraction ranged from 0.0015 ± 0.00010 to 0.998 ± 0.0016 for the glycerol mixtures and 0.00506 ± 0.000019 to 0.999 ± 0.0038 for the 1,2-propanediol mixtures (k = 2 expanded uncertainty). The headspace concentration was converted to nicotine partial pressure at 298.15 K using the ideal gas law, followed by the Clausius-Clapeyron equation. Both solvent systems had a positive deviation of nicotine partial pressure from ideal behavior, but the deviation of the glycerol mixtures was much greater than that of the 1,2-propanediol mixtures. For mole fractions of about 0.02 or less, the glycerol mixtures had nicotine activity coefficients of 11, while that for the 1,2-propanediol mixtures was 1.5. The Henry's law volatility constant and infinite dilution activity coefficient ± expanded uncertainty for nicotine from glycerol mixtures (51.4 ± 1.8 Pa and 12.4 ± 1.5, respectively) were approximately an order of magnitude greater than those from 1,2-propanediol mixtures (5.26 ± 0.52 Pa and 1.42 ± 0.14, respectively).

Effect of selenate on treatment of glycerol containing wastewater in UASB reactors

The effect of selenate on the removal of glycerol in up-flow anaerobic sludge blanket (UASB) reactors was investigated. Two UASB reactors, RControl and RSelenium, were operated at a hydraulic retention time of 48 h and an upflow velocity of 2 m/h at 37 °C. A GAL (glucose, acetate and lactate) and glycerol mixture were used as the only feedstock throughout the experiment for RControl. After acclimation to GAL and glycerol in the start-up period, RSelenium was additionally exposed to selenate (SeO42−) concentrations from 1.43 to 71.49 mg/L (10–500 μM) in a stepwise manner. An average daily methane yield of about 150 mL/g COD, which was comparable with RControl, and 90% Se removal were achieved until 400 μM SeO42−. Simultaneously, SeO42− was reduced to elemental Se or metal selenide, supported by X-ray diffraction, as well as scanning and transmission electron microscopy. However, the methane production rapidly deteriorated when the influent SeO42− concentration was increased to 500 μM. The Se toxicity was evident from the reduction in the activity of Methanosaeta. This study showed that the SeO42− concentration, but not the COD/SeO42− ratio, governs the AD of selenate rich wastewaters.

Improved Antioxidant and Mechanical Properties of Food Packaging Films Based on Chitosan/Deep Eutectic Solvent, Containing Açaí-Filled Microcapsules.

The development of biobased antioxidant active packaging has been valued by the food industry for complying with environmental and food waste concerns. In this work, physicochemical properties for chitosan composite films as a potential active food packaging were investigated. Chitosan films were prepared by solution casting, plasticized with a 1:2 choline chloride: glycerol mixture as a deep eutectic solvent (DES) and incorporated with 0-10% of optimized açaí oil polyelectrolyte complexes (PECs). Scanning electron microscopy and confocal laser scanning microscopy revealed that the chitosan composite films were continuous and contained well-dispersed PECs. The increased PECs content had significant influence on the thickness, water vapor permeability, crystallinity (CrD) and mechanical and dynamic behavior of the films, as well as their antioxidant properties. The tensile strength was reduced in the following order: 11.0 MPa (control film) > 0.74 MPa (5% DES) > 0.63 MPa (5% DES and 5% PECs). Films containing 2% of PECs had an increased CrD, ~6%, and the highest elongation at break, ~104%. Films with 1% of PECs displayed the highest antioxidant properties against the ABTS and DPPH radicals, ~6 and ~17 mg TE g-1, respectively, and highest equivalent polyphenols content (>0.5 mg GAE g-1). Films with 2% of particles were not significantly different. These results suggested that the chitosan films that incorporated 1-2% of microparticles had the best combined mechanical and antioxidant properties as a potential material for food packaging.

An ultralow-friction, low-temperature-lubrication, anti-volatilization and anti-corrosion organohydrogel merely containing nanosilica gelator

Although hydrogel lubricants are effective in eliminating problems caused by creeping or leakage of conventional liquid lubricants, they are easy to encounter issues such as solvent evaporation, electrochemical corrosions to metallic materials and freezing at sub-zero temperatures during the lubrication process. Here we created an organohydrogel lubricant with effective anti-freezing, anti-volatile and anti-corrosive performances using a ternary mixture of colloidal silica nanoparticles, glycerol and water. The hydrogel could attain a very low coefficient of friction at room temperature and could maintain its lubricity even when the environmental temperature reached as low as − 80 °C. Its lubrication mechanism was a synergistic effect between the formation of a physically protective film of glycerol/water mixture and the rolling and repairing actions of silica particles. The presence of glycerol endowed the hydrogel excellent resistance to water volatilization and electrochemical corrosions. Our study is anticipated to find applications in mechanical engineering, metal processing and aerospace industry.

A New Green Coating for the Protection of Frescoes: From the Synthesis to the Performances Evaluation

This work presents the formulation and characterization of a new product for the protection of outdoor frescoes from aggressive environmental agents. The formulation is designed as an innovative green coating, prepared through a zero-waste one-pot-synthetic method to form silver nanoparticles (AgNPs) directly in a chitosan-based medium. The AgNPs are seeded and grown in a mixed hydrogel of chitosan, azelaic, and lactic acid, by the reduction of silver nitrate, and using calcium hydroxide as precipitating agent. The rheological properties of this coating base are optimized by the addition of a solvent mixture of glycerol and ethanol with a 1:1 volume ratio. The new formulation and two commercial products (Paraloid® B72 and Proconsol®) are then applied by brush to ad hoc mock-ups to be evaluated for chemical stability, color and gloss variations, morphological variation, hydrophobicity, and water vapor permeability via Fourier-transform infrared spectroscopy (FT-IR) in attenuated total reflection (ATR) mode, spectrophotometer analysis, stereomicroscope observations, UNI EN 15802, and UNI EN 15803, respectively. The results show that the application of the hybrid chitosan-AgNPs coating is promising for the protection of outdoor frescoes and that it can underpin the development of new products that address the lack of conservation strategies specifically designed for wall painting.

Evaluation of oxalic acid with glycerin efficacy against Varroa destructor (Varroidae): a four year assay

Beekeepers in order to control the Varroa population, apply oxalic acid (OA) by trickling, spraying, evaporating, or fumigating, onto broodless colonies for higher efficacy. Recently, a new method was developed using strips with OA and glycerin during brood-rearing periods. However, there has been little research regarding the optimum concentration of the active ingredient and the suitable solvents to reach maximum efficacy. Thus, in the present study, we applied strips with different concentrations of OA in different mixtures of glycerin, assessed the efficacy of the method throughout a 4-year experiment, and compared it with others, commonly followed by beekeepers. Among the tested concentrations of OA, the optimum was 21% (w/v) (60 g OA, 130 mL glycerin, and 100 mL water), while the presence of water made the strips more manageable. The corrected efficacy of the method ranged from 90.4% to 94.5%, despite the different climate conditions prevailing each year and the presence of brood. All the tested concentrations presented a high number of fallen mites in the first 15–18 days, as glycerin releases OA slowly into the hive. On the other hand, synthetic acaricides or other methods (fumigation, essential oils) presented a corrected efficacy range from 10.1% to 85.6%, requiring more in some formulations repetitions. No bees’ toxicity was observed in all study cases. The results showed that the application of strips with 21% (w/v) OA diluted in glycerin and water seems to be more practical, leading to a successful Varroa control even in seasons with brood presence.

Effects of LLDPE on Mechanical Properties, Degradation Performance, and Water Absorption of Thermoplastic Sago Starch Blends

The purpose of this study was to improve the mechanical and physical properties, degradation performance, and water absorption of a thermoplastic mixture of sago starch with the addition of Linear Low-Density Polyethylene (LLDPE). The method used is the grafting method where polyethylene is grafted onto Maleic Anhydride (LLDPE-g-MA). In this research, Thermoplastics Sago Starch (TPSS) was made with a mixture of Sago Starch (65%) and Glycerol (35%), added with water as a solution. Compatibilizer (PE-g-MA) was made by reacting LLDPE (88%) and Maleate Anhydride (9%) with an additional initiator of Benzoyl Peroxide (3%). The concentration of LLDPE varied from 10,15, 20, 25, and 30%. Substances were mixed into an internal mixer Thermo Haake Polydrive with a speed of 100

Multiphysics Experimental Approaches for Insight into the Hydrogen Bonded Structures of Ethylene Glycol and Glycerol Mixtures toward Green Solvent Technology

Alcohols and their mixtures are credited most important polar solvents for advances in pharmaceutical, chemical,biological, thermal, and material technologies. A rigorous study for the characterization of hydrogen bonded heterogeneousintermolecular structures that formed in a mixed solvent based on alcohols containing two and three hydroxyl groupsmolecules is crucial to specific technological and industrial applications. Hence, in this work, the multiphysics experimentalapproaches including the measurements of dielectric, electrical, viscous, acoustic, thermal, and optical properties are appliedand analyzed to confirm the behaviour of hydrogen bonded molecular structures of ethylene glycol (EG; dihydric alcohol)with glycerol (Gl; trihydric alcohol) over the entire concentration range of EG+Gl mixtures at 298.15 K. The static dielectricpermittivity, direct current electrical conductivity, low frequency relaxation time, and refractive index values of the EG+Glmixtures are reported. Additionally, dynamic viscosity, density, ultrasound velocity, adiabatic compressibility,intermolecular free length, acoustic impedance, free volume, Rao’s constant, Wada constant, and viscoacoustic relaxationtime of the EG+Gl mixtures are determined, and also explored their significance to these alcohols molecular interactions.Ultraviolet-visible range absorbance behaviour of the alcohol mixtures is characterized in detail and confirmed theelectronic transitions at higher energy ultraviolet radiations. The detailed analysis of all the experimental results along withthe consideration of excess properties evidenced the formation of heterogeneous intermolecular hydrogen bonded structuresin these Newtonian-type alcohols mixtures. A small to adequate variation in the thermodynamical and other investigatedproperties with the concentration variation showed that the EG+Gl mixture can be optimized as a green solvent according tothe prerequisite properties for huge advances in soft condensed matter technologies.

Carbon Dioxide Capture with Choline-Based DESs Solvents

Deep eutectic solvents (DES) are an interesting alternative to conventional amines. Due to their biodegradability, lower toxicity and lower prices, DES are considered “more benign” sorbents for CO2 capture than ionic liquids. To study the effect of water on the properties of choline chloride (ChCl)/glycerol mixtures (1:3 on a molar basis), the density and viscosity of ChCl/Gly with different water content (30%, 40% and 50%) were measured at temperature from 293.15 K to 333.15 K at atmospheric pressure, the CO2 solubility in (ChCl/Gly) with water was determined from 293.15 K to 373.15 K and at pressure from 0.5 MPa to 3 MPa. The result shows the dramatically influence of water in the viscosity but not in the CO2 solubility and Absorption.

Влияние растворов борной кислоты в органических растворителях на продуктивность и химический состав зеленой массы клевера лугового

A comparative study of the effectiveness of boron in various forms (aqueous solution / chelated form) on the yield and quality indicators of Martum variety meadow clover herbage was carried out. Chelated forms were solutions of boric acid in organic liquids: monoethanolamine, diethanolamine, triethanolamine, glycerol, ethylene glycol. The plants fertilized with solutions of boric acid in orga¬nic solvents were bulkier and their biomass grew more intensively. The use of an aqueous solution of boric acid (the traditional form of boron microfertilizers) increased the plant growth by only 6.2 % compared to the variant without fertilization. The use of organic solvents led to more significant increase in the height of red clover: its increase compared to control test varied from 5.5 to 19.6 cm. The tallest plants were observed in the variant with the use of boric acid dissolved in ethylene glycol, which exceeded the control value by 1.3 times. Foliar top dressing with boric micronutrient fertilizers allowed increasing the herbage of the experimental crop by 7.4–78.5 %, in relation to the control test. The use of triethanolamine, glycerol, and ethylene glycol as solvents contributed to the maximum significant growth of the vegetative mass of clover, which was 8.1, 7.7 and 9.5 t/ha higher, respectively, compared to the unfertilized variant. The collection of dry matter in the experimental variants increased by 0.1–1.1 t/ha. The highest value of this indicator was noted during foliar treatment of clover with the solution of boric acid based on ethylene glycol, which exceeded the value of the control test by 73.3 %, as well as the variant with an aqueous solution of boric acid by 62.5 %. In addition to taking into account the total content of organic or mineral compounds in the clover phytomass, the content of the main nutrients – nitrogen, phosphorus, and potassium – was determined. The highest concentration of nitrogen was observed after adding a mixture of boric acid and glycerol, which is 24.2 % higher than the value in the control test, as well as 33.1 % higher than the variant after the aqueous solution of boric acid. The content of phosphorus in the clover herbage was maximal in the variant using a solution of boric acid in glycerol; it exceeded the control test by 15.4 %. The dissolution of boric acid in water and ethylene glycol, on the contrary, significantly reduced the concentration of this element by 11.5 % compared to the control test. The content of potassium in the clover herbage in the control test was 1.95 %, while the use of solutions of boric acid in organic solvents for foliar feeding led to an increase in this indicator by an average of 1.04 times. At the same time, the maximal increase in the indicator under consideration in the variant where a solution based on diethanolamine was used equaled 7.7 % to the corresponding value of the unfertilized variant and 8.2 % to the variant using an aqueous solution of boric acid. The use of boric acid contributed to a slight decrease in the content of nitrates, and the options with the use of di- and triethanolamine were characterized by the greatest effect in this case.

Volumetric, dielectric, and spectroscopic studies for the binary mixtures of glycerol and dimethylacetamide at T= (298.15–323.15) K

In this paper, density (ρ), volumetric (Vm), and thermal expansibilities (αP) of Glycerol (Gly) with Dimethylacetamide(DMA) binary mixtures are measured in the temperature range298.15 K-323.15 K. The dielectric permittivity of Gly + DMAbinary mixtures is also determined at different temperatures in the microwave frequency range 0.02 < ν/GHz < 20. The relaxation time (τ) of the binary mixtures is computed from the Havriliak-Negami relation. The excess parameters of volumetric (VmE), thermal expansibilities (αPE), refractive indices), relaxation time (1/τ) E, and molar polarization (PmE) are fitted with the Redlich-Kister polynomial equation. The negative values of VmE, αPE, nDE, and (1/τ) E parameters at all concentrations and temperatures suggest the presence of hydrogen bond interactions in the liquid system. The presence of H- bond between Gly & DMA is conformed from the FT-IR Spectra. The results were analysed in terms of molecular interactions among the components in the mixture mediated by hydrogen bonding.

Developing transdermal patch from Momordica charantia L. fruit using polyvinyl alcohol and ethyl cellulose potentially as anti-inflammatory dosage form

Introduction: Anti-inflammatory medication is currently sufficiently developed for the ease of application and effectiveness of therapy. Development of natural ingredients that are applied through the skin is needed to get a profitable product. This study aimed to develop bitter melon (Momordica charantia L.) fruit as an anti-inflammatory agent using transdermal patch preparations. Materials and Methods: Dried bitter melon powder was macerated using 96% ethanol, followed by evaporation until a viscous extract was obtained. Bitter melon fruit extract (BMFE) 30% was prepared into three patch transdermal preparations using combinations of polyvinyl alcohol (PVA) and ethyl cellulose (EC) as bases. A mixture of BMFE, propylene glycol, and glycerin was added to the bases and mixed until homogeneous. The entire mass was poured into a mold, coated with aluminum foil, allowed to stand for 24 h, and dried in an oven at 40 °C for 30 min. All preparations of the transdermal patch were evaluated for their physical and chemical characteristics as well as their anti-inflammatory effects Results: All transdermal patch preparations had solid form, visible brown, weight 0.424 -0.432 g, thickness 0.344 – 0.320 mm, folding endurance of more than 300, pH 4.84 – 4.87, and hygroscopicity 6.50 - 6.99 %. All preparations showed a decrease in the diameter of the edema, but this was not significant; after the 90th minute, the edema diameter was significantly reduced. Conclusion: This study showed that BMFE can be used for anti-inflammatory patch preparation and has the potential to be developed as a transdermal anti-inflammatory dosage form.