A three-dimensional structural integrity analysis using the eXtended Finite Element Method (XFEM) is considered for simulating the crack behaviour of a chopped fibre-glass-reinforced polyester (CGRP) cruciform specimen subjected to a quasi-static tensile biaxial loading. This is the first time this problem is accomplished for computing the stress intensity factors (SIFs) produced in the biaxially loaded area of the cruciform specimen. A static crack analysis for the calculation of the mixed-mode SIFs is carried out. SIFs are calculated for infinite plates under biaxial loading as well as for the CGRP cruciform specimens in order to review the possible edge effects. A ratio relating the side of the central zone of the cruciform and the crack length is proposed. Additionally, the initiation and evolution of a three-dimensional crack are successfully simulated. Specific challenges such as the 3D crack initiation, based on a principal stress criterion, and its front propagation, in perpendicular to the principal stress direction, are conveniently addressed. No initial crack location is pre-defined and an unique crack is developed. Finally, computational outputs are compared with theoretical and experimental results validating the analysis.