Mixed Diesters Research Articles

Preparation of some mixed diesters of aliphatic diols and their evaluation as plasticizers

AbstractMixed diesters of three diols‐ethylene glycol, diethylene glycol, and 2‐butene‐1,4‐diol—were prepared wherein one of the ester moieties was benzoate. The laurates were shown to be excellent plasticizers for polyvinyl chloride (PVC) resin. Diesters containing two aroyl groups, or benzoyl and a short branched‐chain alkanoyl group were also shown to be compatible plasticizers for PVC resin. Longer chain acids, including oleic and erucic, gave incompatible plasticizers. Benzoyloxyethoxyethyl laurate plasticized PVC had low temperature properties, volatility, and thermal stability superior to PVC plasticized with di‐2‐ethylhexyl phthalate.

Studies of phosphorylation. III. Effect of metallic compound on the phosphorylation of alcohols, phosphates, and nucleosides by 8-quinolyl phosphates.

Influence of metallic compounds in phosphorylation of alcohols, phosphates, and nucleosides by means of 8-quinolyl phosphates was investigated. The mixed diesters of phosphoric acid (III) and pyrophosphates (V) were obtained in good yields when alcohols or phosphates were allowed to react with phenyl 8-quinolyl hydrogen phosphate (I) in the presence of a metallic compound. The effect of various metal components was examined and the copper [II] ion gave the best result. The reaction of tris (8-quinolyl) phosphate (VI) with nucleosides in the copper acetylacetonate resulted in the formation of corresponding nucleotides (VIII) in a high yield.

Preparation of Some New Ethylene Glycol Monoesters and Mixed Diesters of Fatty Acids

AbstractTri‐(2‐hydroxyethyl)‐orthoborate, obtained by reaction of ethylene glycol with boric acid, was esterified with palmitic, stearic, arachidic, oleic, hydnocarpic, elaidic and stearolic acids. Pure monoesters were obtained on hydrolysis with water in high yields. Monoelaidate and monostearolate are reported for the first time. The monoesters were reacted with acyl chlorides to yield the mixed diesters, viz., oleostearate, oleopalmitate, oleoarachidate, oleoelaidate, oleostearolate, elaidohydnocarpate, stearocaproate and stearolaurate. Except oleostearate the other compounds are reported for the first time.

A New Phosphorylating Reagent. III. Preparation of Mixed Diesters of Phosphoric Acid by the Use of an Activatable Protecting Group

Abstract A novel method for the preparation of mixed diesters of phosphoric acid has been investigated. It was found that mixed diesters of phosphoric acid were prepared by the reaction of alkyl 2-chloromethyl-4-nitrophenyl hydrogen phosphates with alcohols in dry pyridine. On the other hand, these diesters were also obtained from dialkyl 2-chloromethyl-4-nitrophenyl phosphates on hydrolysis under mild conditions. By using both of these methods, analytically pure samples of mixed diesters of phosphoric acid could be obtained in high yields.

Comparative rate of lipolysis of different fatty acids in pancreatic lipase hydrolysis of ethylene glycol mixed diesters

Comparative rate of lipolysis of different fatty acids in pancreatic lipase hydrolysis of ethylene glycol mixed diesters

A new phosphorylating reagent. II. Preparation of mixed diesters of phosphoric acid by the use of alkyl 2-chloromethyl-4-nitrophenyl hydrogen phosphates

A new phosphorylating reagent. II. Preparation of mixed diesters of phosphoric acid by the use of alkyl 2-chloromethyl-4-nitrophenyl hydrogen phosphates

Cholest- 4-en-26-ol- 3-on und cholesta-1, 4-dien-26-ol- 3-on als komponenten eines neuen mikrobiell gebildeten estertyps

Zusammenfassung 1. 1. Two 26-hydroxy compounds were isolated from two fermentation products of cholesterol with Mycobacterium smegmatis . The structure was elucidated by chemical reactions, NMR and mass spectroscopy. The whole fermentation products are mixed diesters of succinic acid with cholesterol and either cholest- 4 -en-26-ol- 3 -one or cholesta-1, 4 -dien-26-ol- 3 -one. 2. 2. The 26-hydroxylated fermentation products of cholesterol are formed via cholest-4-en-3-one. 3. 3. The introduction of the 26-hydroxy-group is discussed as the first step in the oxidative degrActa.tion of the cholesterol side chain by M. smegmatis .