The problem of the missing matter in the Universe is reviewed and discussed in terms of massive neutrinos. The primordial abundances of light elements produced during the big bang nucleosynthesis can be used to determine firm bounds on the number of neutrino flavours and on the ratio of baryon to photon densities in the Universe. These limits imply that nonbaryonic matter is the dominant constituent of large-scale cosmic structures, being massive neutrinos the best guess for such a matter. In order that the Universe be closed, a value of the neutrino rest mass is derived, which agrees with the bounds obtained from the dynamics of galaxies and clusters of galaxies. It is also shown that density perturbations can hardly grow in a nucleon-dominated Universe, and massive neutrinos may be the seed for nucleon condensations. All these astrophysical and cosmological considerations suggest a lower and an upper bound of the neutrino rest mass.