The purpose of the ECRIX-H experiment is to study the behaviour of a composite ceramic target made of AmO 1.62 microdispersed in an MgO matrix irradiated for 318 EFPD in the Phenix sodium-cooled fast reactor (SFR), in a specific carrier sub-assembly equipped with annular blocks of CaH x acting as a neutron moderator. Results indicate that magnesia-based inert matrix targets display satisfactory behaviour and moderate swelling under irradiation, even for significant quantities of helium produced and a high burn-up. On this basis, the design of transmutation fuel pins for recycling of minor actinides (MA) in accelerator-driven systems (ADS) or in fast neutron reactors (FR) could be optimised so as to increase their performance level (initial MA content, burn-up, etc.). The measured Am fission rate (25 at.%) was found to be lower than that predicted by neutronic simulations probably due to the inaccuracies linked to the complexity of neutron modelling and the uncertainties on nuclear data related to moderated neutron spectrum. In addition, as most of the initial Am transmuted into Pu under irradiation, a PuO x -type phase was created within the initial AmO 1.62 particles, leading to the incomplete dissolution of the irradiated targets under standard reprocessing conditions. This issue will have to be considered and investigated in greater detail for all transmutation fuels and targets devoted to the multi-recycling of MA.