A hybrid strategy has been proposed to reduce the wrong clustering on Ambulatory ECG (electrocardiogram). Since Ambulatory ECG is usually composed by 24 hours data, the number of individual ECG waveform can reach to 100,000, the request for accurate clustering result is highly required. The proposed strategy adopted some intelligent algorithms to solve the above problem. It clusters ECG waveform sample (selected from Ambulatory ECG) synchronously by Max-Min distance clustering algorithm, K-means algorithm and Simulated annealing algorithm first. And then, it adopted all three outputs from the above three algorithms as input on Back Propagation Artificial Neural Network (BP ANN). In the end, we got more accurate clustering result from the output of ANN. For testing the results, data of MIT/BIH arrhythmia database were used for experiments. After the controlled trial on MIT/BIH data, it can be safely concluded that the clustering result achieved by improved strategy can got more accurate than that by the traditional clustering algorithm. An average accuracy ratio is about 94.6%, 1.6% higher than k-means algorithm averagely and 1.3% higher than Simulated Annealing algorithm averagely.