Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy. Surgery is generally preferred in cases of CTS which do not respond to conservative measures. We evaluated the results and complications of patients who underwent mini open release for CTS. Mini-open carpal tunnel release was performed in 36 hands of 30 patients with CTS. There were 27 females, and 3 males, with ages ranging from 23 to 71 years. (mean age 45.6 years) Clinical and electromyographic findings were compatible with CTS. All cases were done under local anesthesia without using a tourniquet. The mean follow-up period was 16 months. (range 10 to 20 months) The mean duration of the operation was 15 minutes (range: 10-20 minutes) No serious surgical complication has occurred. Excellent results were achieved in 32 hands (88%). Mini-open carpal tunnel release is a safe and simple procedure with satisfactory outcome.