Millisecond Duration Research Articles

Fast radio bursts and white hole signals

We estimate the size of a primordial black hole exploding today via a white hole transition, and the power in the resulting explosion, using a simple model. We point out that Fast Radio Bursts, strong signals with millisecond duration, probably extragalactic and having unknown source, have wavelength not far from the expected size of the exploding hole. We also discuss the possible higher energy components of the signal.

GIANT SPARKS AT COSMOLOGICAL DISTANCES?

Millisecond duration bright radio pulses at 1.4-GHz with high dispersion measures (DM) were reported by Lorimer et al., Keane et al., and Thornton et al. Their all-sky rate is $\approx 10^4$/day above $\sim$1 Jy. Related events are "Perytons" -- similar pulsed, dispersed sources, but most certainly local. Suggested models of fast radio bursts (FRBs) can originate in the Earth's atmosphere, in stellar coronae, in other galaxies, and even at cosmological distances. Using physically motivated assumptions combined with observed properties, we explore these models. In our analysis, we focus on the Lorimer event: a 30 Jy, 5-ms duration burst with DM$=$ 375 cm$^{-3}$ pc, exhibiting a steep frequency-dependent pulse width (the {\it Sparker}). To be complete, we drop the assumption that high DMs are produced by plasma propagation and assume that the source produces pulses with frequency-dependent arrival time ("chirped signals"). Within this framework we explore a scenario in which Perytons, the {\it Sparker}, and the FRBs are all atmospheric phenomenon occurring at different heights. This model is {\it ad hoc} in that we cannot explain why Perytons at higher altitudes show greater DMs or exhibit narrower pulses. Nonetheless, we argue the {\it Sparker} may be a Peryton. We end with two remarks. First, the detection of a single FRB by an interferometer with a kilometer (or longer) baseline will prove that FRBs are of extra-terrestrial origin. Second, we urge astronomers to pursue observations and understanding of Perytons since they form (at least) a formidable foreground for the FRBs.

In vivo laser cartilage reshaping with carbon dioxide spray cooling in a rabbit ear model: a pilot study.

Similar to conventional cryogen spray cooling, carbon dioxide (CO2) spray may be used in combination with laser cartilage reshaping (LCR) to produce cartilage shape change while minimizing cutaneous thermal injury. Recent ex vivo evaluation of LCR with CO2 cooling in a rabbit model has identified a promising initial parameter space for in vivo safety and efficacy evaluation. This pilot study aimed to evaluate shape change and cutaneous injury following LCR with CO2 cooling in 5 live rabbits. The midportion of live rabbit ears were irradiated with a 1.45 µm wavelength diode laser (12 J/cm(2)) with simultaneous CO2 spray cooling (85 millisecond duration, 4 alternating heating/cooling cycles per site, 5 to 6 irradiation sites per row for 3 rows per ear). Experimental and control ears (no LCR) were splinted in the flexed position for 30 days following exposure. A total of 5 ears each were allocated to the experimental and control groups. Shape change was observed in all irradiated ears (mean 70 ± 3°), which was statistically different from control (mean 37 ± 11°, P = 0.009). No significant thermal cutaneous injury was observed, with preservation of the full thickness of skin, microvasculature, and adnexal structures. Confocal microscopy and histology demonstrated an intact and viable chondrocyte population surrounding irradiated sites. LCR with CO2 spray cooling can produce clinically significant shape change in the rabbit auricle while minimizing thermal cutaneous and cartilaginous injury and frostbite. This pilot study lends support for the potential use of CO2 spray as an adjunct to existing thermal-based cartilage reshaping modalities. An in vivo systematic evaluation of optimal laser dosimetry and cooling parameters is required.

IMPLEMENTATION OF TRANSMITTER AND RECEIVER ARCHITECTURE FOR PHYSICAL HYBRID INDICATOR CHANNEL OF LTE-ADVANCED USING PARTIAL RECONFIGURATION IN ML605 VIRTEX-6 DEVICE

LTE-A (Long Term Evolution-Advanced) is the fourth generation technology to increase the speed of wireless data network. The LTE-A Physical layer provides both data and control information between an enhanced base station and mobile user equipment which is quite complex and consists of a mixture of technologies. Since there is requirement for more resources to accommodate all the channels in a single FPGA, Partial Reconfiguration (PR) technique is introduced to configure the total hardware into sub modules that configure and operate in different instants of time. PR enables a part of FPGA to be reconfigured, while the rest continues to function without any interruptions and reduces the hardware resource power and fabric area. This work proposes the realization of transmitter and receiver architecture of Physical Hybrid Indicator Channel (PHICH) channel for LTE-A using partial reconfiguration on xc6vlx240tff1156-1 FPGA. The receiver architecture for PHICH is to report the correct reception of uplink user data to the User Equipment (UE) in the form of Acknowledgment (ACK), or Negative ACK (NACK) in a 1 millisecond duration sub-frame of Long Term Evolution (LTE) System. The modules for the different diversities are reconfigured based on the control signals from the transmitter.

Millisecond duration pulses for flow-through electro-induced protein extraction from E. coli and associated eradication

Pulsed electric fields are used to induce membrane permeabilization on cells. In the case of species with cell wall (yeasts, microalgae), it was previously shown that when the pulse duration was several ms long, this resulted in a cytoplasmic soluble protein slow leakage. In this work, we show that a similar consequence can be obtained with different strains of E. coli. Experimental evidences of a resulting wall alteration are described. Pre-industrial flow process pilots are used. As the membrane electropermeabilization can be irreversible by applying a proper choice of the pulse parameters, this approach is used for bacterial inactivation in flow process. It is observed that sub-millisecond pulse trains are more cost effective than longer ones.

The importance of source positions during radio fine structure observations

The measurement of positions and sizes of radio sources in the observations of the fine structure of solar radio bursts is a determining factor for the selection of the radio emission mechanism. The identical parameters describing the radio sources for zebra structures (ZSs) and fiber bursts confirm there is a common mechanism for both structures. It is very important to measure the size of the source in the corona to determine if it is distributed along the height or if it is point-like. In both models of ZSs (the double plasma resonance (DPR) and the whistler model) the source must be distributed along the height, but by contrast to the stationary source in the DPR model, in the whistler model the source should be moving. Moreover, the direction of the space drift of the radio source must correlate with the frequency drift of stripes in the dynamic spectrum. Some models of ZSs require a local source, for example, the models based on the Bernstein modes, or on explosive instability. The selection of the radio emission mechanism for fast broadband pulsations with millisecond duration also depends on the parameters of their radio sources.

Calcium influx affects intracellular transport and membrane repair following nanosecond pulsed electric field exposure.

The cellular response to subtle membrane damage following exposure to nanosecond pulsed electric fields (nsPEF) is not well understood. Recent work has shown that when cells are exposed to nsPEF, ion permeable nanopores (<2 nm) are created in the plasma membrane in contrast to larger diameter pores (>2 nm) created by longer micro- and millisecond duration pulses. Nanoporation of the plasma membrane by nsPEF has been shown to cause a transient increase in intracellular calcium concentration within milliseconds after exposure. Our research objective is to determine the impact of nsPEF on calcium-dependent structural and repair systems in mammalian cells. Chinese hamster ovary (CHO-K1) cells were exposed in the presence and absence of calcium ions in the outside buffer to either 1 or 20, 600-ns duration electrical pulses at 16.2 kV/cm, and pore size was determined using propidium iodide and calcium green. Membrane organization was observed with morphological changes and increases in FM1-43 fluorescence. Migration of lysosomes, implicated in membrane repair, was followed using confocal microscopy of red fluorescent protein-tagged LAMP1. Microtubule structure was imaged using mEmerald-tubulin. We found that at high 600-ns PEF dosage, calcium-induced membrane restructuring and microtubule depolymerization coincide with interruption of membrane repair via lysosomal exocytosis.

A model for fast extragalactic radio bursts

Abstract Bursts of millisecond duration were recently discovered in the 1 GHz band. There is a strong evidence that they come from ∼1 Gpc distances, which implies extraordinary high-brightness temperature. I propose that these bursts could be attributed to synchrotron maser emission from relativistic, magnetized shocks. At the onset of the magnetar flare, a strongly magnetized pulse is formed, which propagates away through the relativistic magnetar wind and eventually reaches the nebula inflated by the wind within the surrounding medium. I show that the observed radio bursts could be generated at shocks formed via the interaction of the magnetic pulse with the plasma within the nebula. The model predicts strong millisecond bursts in the TeV band, which could be observed even from distant galaxies.

Laser surface texturing of gray cast iron for improving tribological behavior

Laser surface texturing process involves creation of microfeatures, e.g., tiny dimples, usually distributed in a certain pattern, covering only a fraction of the surface of the material that is being treated. The process offers several advantages for tribological applications, including improved load capacity, wear resistance, lubrication lifetime, and reduced friction coefficient. In the present study, the surface modification of gray cast iron, using millisecond (λ = 1,064 nm), nanosecond (λ = 1,064 nm) and femtosecond (λ = 800 nm) pulse duration laser irradiation, is adopted to establish a particular geometrical pattern with dimple features and dimensions, to improve wear and friction behavior. The effect of various laser processing parameters, including laser pulse energy, pulse duration and processing speed, on the performance characteristics of the laser-treated samples is investigated. The microtextured surfaces were produced on gray cast iron using different millisecond (0.5 ms), nanosecond (40 ns) and femtosecond (120 fs) laser source with the dimple depth between 3 and 15 μm. The coefficient of friction for the untextured surface was ~0.55, millisecond laser textured ~0.31, nanosecond laser textured ~0.02 and femtosecond laser ~0.01, under normal force of 50 N and sliding speed of 63 mm/s. Surface texturing of the gray cast iron surface using femtosecond pulse duration resulted in significant improvement in wear resistance in comparison to the untextured as well as millisecond and nanosecond laser-textured surface.

Experimental results of testing high-temperature-high-current pulsed operation of SiC MOSETs and SiC diodes

Using hot plate experiments testing to a maximum temperature of 200 °C, we performed tests to determine the maximum single pulse current allowable for Cree CMF20120D SiC MOSFETs and Cree C4D40120D Schottky diodes. Using single pulse switching of a resonant circuit, a half-sine shaped current pulse of 5∼10 μsec duration was used to test the devices. A criterion for maximum allowable peak current was determined from the point of dramatic increase in conduction loss as a function of peak current. At 200 °C, maximum single pulse current was found to be 200 amp for the SiC MOSFET and about 500 amp for the SiC Schottky diode (both legs in parallel). We also report measurements of leakage current on the devices as a function of temperature, and will present measurements on an IGBT device of comparable current rating for comparison. Simple measurements of this type are a useful way of determining operational limits of SiC devices at temperatures that are not reported in the device data sheet.

Kerr electro-optic field mapping study of the effect of charge injection on the impulse breakdown strength of transformer oil

The smart use of charge injection to improve breakdown strength in transformer oil is demonstrated in this paper. Hypothetically, bipolar homo-charge injection with reduced electric field at both electrodes may allow higher voltage operation without insulation failure, since electrical breakdown usually initiates at the electrode-dielectric interfaces. To find experimental evidence, the applicability and limitation of the hypothesis is first analyzed. Impulse breakdown tests and Kerr electro-optic field mapping measurements are then conducted with different combinations of parallel-plate aluminum and brass electrodes stressed by millisecond duration impulse. It is found that the breakdown voltage of brass anode and aluminum cathode is ∼50% higher than that of aluminum anode and brass cathode. This can be explained by charge injection patterns from Kerr measurements under a lower voltage, where aluminum and brass electrodes inject negative and positive charges, respectively. This work provides a feasible approach to investigating the effect of electrode material on breakdown strength.

Short‐term synaptic plasticity and the ‘active calcium’ hypothesis at a central synapse

Short‐term synaptic plasticity and the ‘active calcium’ hypothesis at a central synapse

Potential production of Hughlings Jackson's “parasitic consciousness” by physiologically-patterned weak transcerebral magnetic fields: QEEG and source localization

Exotic experiences such as the sensing of another consciousness or the detachment of consciousness from the body are occasionally reported by individuals with partial seizures from a temporal lobe focus. The experiences display the characteristics of Hughlings Jackson's “parasitic consciousness”. We have hypothesized that these experiences are encouraged by slight discrepancies in hemispheric activity that can be simulated by application of weak, physiologically-patterned magnetic fields across the cerebral hemispheres. Electroencephalographic and Low Resolution Electromagnetic Tomography (sLORETA) data revealed altered activity bands within specific regions within the cerebral cortices during these experiences. The clear changes in power of brain activity were discerned after consistent durations of exposure to specifically patterned weak magnetic fields. Millisecond range point durations were required. The technology may be useful to explore the subjective components associated with complex partial seizures.

A Population of Fast Radio Bursts at Cosmological Distances

Searches for transient astrophysical sources often reveal unexpected classes of objects that are useful physical laboratories. In a recent survey for pulsars and fast transients, we have uncovered four millisecond-duration radio transients all more than 40° from the Galactic plane. The bursts' properties indicate that they are of celestial rather than terrestrial origin. Host galaxy and intergalactic medium models suggest that they have cosmological redshifts of 0.5 to 1 and distances of up to 3 gigaparsecs. No temporally coincident x- or gamma-ray signature was identified in association with the bursts. Characterization of the source population and identification of host galaxies offers an opportunity to determine the baryonic content of the universe.

Macrocircuits for Sound Localization Use Leaky Coincidence Detectors and Specialized Synapses

The auditory system computes sound location by detecting submillisecond time differences in the arrival of sound at the two ears. Studies by van der Heijden etal. (2013) and Roberts etal. (2013) in this issue of Neuron shed light on how this is accomplished by the interaction of excitatory and inhibitory synapses.

Magnetothermoacoustics from magnetic nanoparticles by short bursting or frequency chirped alternating magnetic field: A theoretical feasibility analysis

To propose an alternative method of thermoacoustic wave generation based on heating of magnetic nanoparticles (MNPs) using alternating magnetic field (AMF). The feasibility of thermoacoustic wave generation from MNPs by applying a short-burst of AMF or a frequency-modulated AMF is theoretically analyzed. As the relaxation of MNPs is strongly dependent upon the amplitude and frequency of AMF, either an amplitude modulated, fixed frequency AMF (termed time-domain AMF) or a frequency modulated, constant amplitude AMF (termed frequency-domain AMF) will result in time-varying heat dissipation from MNPs, which has the potential to generate thermoacoustic waves. Following Rosensweig's model of specific power loss of MNPs in a steady-state AMF, the time-resolved heat dissipations of MNPs of superparamagnetic size when exposed to a short bursting of AMF and∕or to a linearly frequency chirped AMF are derived, and the resulted acoustic propagation is presented. Based on experimentally measured temperature-rise characteristics of a superparamagnetic iron-oxide nanoparticle (SPION) matrix in a steady-state AMF of various frequencies, the heat dissipations of the SPION under time-domain and frequency-domain AMF configurations that could have practical utility for thermoacoustic wave generation are estimated. The initial rates of the temperature-rise of the SPION matrix were measured at an iron-weight concentration of 0.8 mg∕ml and an AMF frequency of 88.8 kHz to 1.105 MHz. The measured initial rates of temperature-rise were modeled by Rosensweig's theory, and projected to 10 MHz AMF frequency, at which a 1 μs bursting corresponding to a 1.55 mm axial resolution of acoustic detection could contain 10 complete cycles of AMF oscillation and the power dissipation is approximately 84 times of that at 1 MHz. Exposing the SPION matrix to a 1 μs bursting of AMF at 10 MHz frequency and 100 Oe field intensity would produce a volumetric heat dissipation of 7.7 μJ∕cm(3) over the microsecond duration of the AMF burst. If the SPION matrix is exposed to a 1 ms long AMF train at 100 Oe field intensity that chirps linearly from 1 to 10 MHz, the volumetric heat dissipation produced over each 2π phase change of the AMF oscillation is estimated to increase from 0.15 to 1.1 μJ∕cm(3) within the millisecond duration of the chirping of AMF. The heat dissipations upon SPION (∼1 mg∕ml iron-weight concentration) by a 1 μs bursting of 100 Oe AMF at 10 MHz and a 1 ms train of 100 Oe AMF that chirps linearly from 1 to 10 MHz were estimated to determine the potential of thermal-acoustic wave generation. Although thermoacoustic wave generation from MNPs by time- or frequency-domain AMF applications is predicted, the experimental generation of such a wave remains challenging.

Low-temperature fabrication of spiking soma circuits using nanocrystalline-silicon TFTs.

Spiking neuron circuits consisting of ambipolar nanocrystalline-silicon (nc-Si) thin-film transistors (TFTs) have been fabricated using low temperature processing conditions (maximum of 250 °C) that allow the use of flexible substrates. These circuits display behaviors commonly observed in biological neurons such as millisecond spike duration, nonlinear frequency-current relationship, and spike frequency adaptation. The maximum drive capacity of a simple soma circuit was estimated to be approximately 9200 synapses. The effect of bias stress-induced threshold voltage degradation of component nc-Si TFTs on the spike frequency of soma circuits is explored. The measured power consumption of the circuit when spiking at 100 Hz was approximately 12 nW. Finally, the power consumption of the soma circuits at different spiking conditions and its implications on a large-scale system are discussed. The fabricated circuits can be employed as part of a compact multilayer learning network.

Eye-safe solid-state quasi-CW Raman laser with millisecond pulse duration

We demonstrate the first quasi-CW (ms-long pulses, pump duty cycle of 10%) end-diode pumped solid state laser generating eye-safe radiation via intracavity Raman conversion. The output power at the first Stokes wavelength (1524nm) was 250mW. A theoretical model was applied to analyze the laser system and provide routes for optimization. The possibility of true CW operation was discussed.

Immunohistochemistry of angiogenesis mediators before and after pulsed dye laser treatment of angiomas.

Tissue effects of vascular lesion laser treatment are incompletely understood. Injury caused by pulsed dye laser (PDL) treatment may result in altered expression of mediators associated with angiogenesis. Eight human subjects had one angioma treated with PDL (7 mm, 1.5 millisecond pulse duration, 9 J/cm(2), cryogen spray cooling of 30 millisecond with a 30 millisecond delay). One week later, three biopsies were taken: normal skin, untreated angioma, angioma post-PDL. Tissue was frozen and sections processed for immunohistochemistry staining of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), matrix metalloproteinase 9 (MMP-9), and angiopoietin 2 (ANG-2). Images were graded in a blinded fashion by a board certified dermatopathologist. There were no clear trends in VEGF expression in the epidermis, dermis, or endothelial cells. As compared to normal skin, angiomas demonstrated the following: bFGF was decreased in the epidermis; MMP-9 was decreased or unchanged in the epidermis and increased in the endothelial cells; ANG-2 was increased in the endothelial cells. When comparing normal skin to angiomas + PDL, bFGF was decreased in the epidermis and increased in the dermis; MMP-9 was decreased or unchanged in the epidermis; ANG-2 was again increased in the endothelial cells. Comparison of staining in angioma to angioma + PDL samples revealed increased dermal bFGF expression. Alterations in angiogenesis mediators were noted after PDL. Angiogenesis mediator changes associated with PDL treatment differed from those previously reported for incisional biopsies. This pilot study can guide future work on laser-induced alterations in vascular lesions and such information may ultimately be used to optimize treatment outcomes.

THE ALLEN TELESCOPE ARRAY FLY'S EYE SURVEY FOR FAST RADIO TRANSIENTS

The relatively unexplored fast radio transient parameter space is known to be home to a variety of interesting sources, including pulsars, pulsar giant pulses and non-thermal emission from planetary magnetospheres. In addition, a variety of hypothesized but as-yet-unobserved phenomena, such as primordial black hole evaporation and prompt emission associated with coalescing massive objects have been suggested. The 2007 announcement by Lorimer et al. of the detection of a bright (30 Jy) radio pulse that was inferred to be of extragalactic origin and the subsequent consternation have demonstrated both the potential utility of bright radio pulses as probes of the interstellar medium and intergalactic medium, as well as the need for wide-field surveys characterizing the fast-transient parameter space. Here we present results from the 450 hour, 150 deg^2 Fly's Eye survey for bright dispersed radio pulses at the Allen Telescope Array (ATA). The Fly's Eye spectrometer produces 128 channel power spectra over a 209 MHz bandwidth, centered at 1430 MHz, on 44 independent signals paths originating with 30 independent ATA antennas. Data were dedispersed between 0 and 2000 pc cm^-3 and searched for pulses with dispersion measures greater than 50 pc cm^-3 between 625 us and 5 s in duration. No pulses were detected in the survey, implying a limiting rate of less than 2 sky^-1 hour^-1 for 10 millisecond duration pulses having apparent energy densities greater than 440 kJy us, or mean flux densities greater than 44 Jy. Here we present details of the instrument, experiment and observations, including a discussion of our results in light of other single pulse searches.