The article examines Iran’s relationship with the Shanghai Cooperation Organization (SCO), analyses the process of establishing cooperation with the member states of this organization, primarily Russia and China, in the field of regional security, as well as the political and economic spheres. The history of Iran’s inclusion in the SCO, the dynamics of cooperation, as well as the impact of this interaction on regional and world politics are explored. The focus is on joint projects, diplomatic, trade and economic relations, as well as potential challenges and prospects for cooperation between Iran and the SCO. The work notes that Iran’s desire for full membership in this organization was reinforced by the confrontation with the leading Western powers led by the United States and fit into the framework of Eastern policy with the prospect of an alliance with Russia and China. It is emphasized that due to opposition to Iran’s desire to strengthen its independence and sovereignty, Western powers prevented its inclusion in the regional or international security architecture. Under these conditions, Iran has intensified its efforts in search of its place in the international security system, relying on the idea of national identity and drawing closer to Russia and China. It is noted that the negative consequences of sanctions, threats of military intervention, cyber warfare and attempts to destabilize the Islamic regime were the main methods of Western policy towards Iran. Based on this, accession to the SCO was considered by the Iranian leadership as the most important task to neutralize Western sanctions and become one of the leaders in the regional security system.