Obese Middle-aged Women Research Articles

실내골프운동이 중년비만 여성의 심박변이도에 미치는 영향

[목적] 본 연구의 목적은 중년비만여성들의 실내골프운동 참여가 자율신경계 균형에 미치는 효과를 검증하는데 있다. [방법] 실내골프운동을 7번 아이언으로 10주간 하프 및 풀 스윙을 거쳐 정확한 타점을 목표로 수행하였다. 효과 검증은 심박변이도를 측정하였고 통계프로그램을 사용하여 각 항목별 측정치를 기술통계량과 이원변량분산 분석을 실시하였다. [결과] 전신 활력(F=6.036, P=.022), 육체적 복합도와 피로도를 반영한 시간영역의 전체 R-R 간격의 표준편차(F=4.823, P=.039), 심장의 안전도를 반영한 연속적인 R-R 간격의 평균제곱 차이의 제곱근 (F=5.055, P=.035)에서 집단 및 시기 간의 상호작용에서 통계적으로 유의한 차이가 나타났다. [결론] 본 연구 결과 골프운동은 중년비만여성들의 전신 활력과 육체적 복합도 및 피로도 그리고 심장의 안전도를 반영한 지표들의 통계적으로 유의한 증가로 자율신경계 균형에 긍정적인 변화를 나타냈다. 따라서 실제 현장에서 중년비만여성들 의 골프운동이 무너진 자율신경계의 균형 및 개선에 도움이 될 것으로 사료된다.

온열요법이 중년 비만 여성의 혈중 Irisin 수준과 당대사 조절인자에 미치는 효과

온열요법이 중년 비만 여성의 혈중 Irisin 수준과 당대사 조절인자에 미치는 효과

Effects of Combined EXERCISE Training on Obesity Indices and VEGF and Endothelin-1 in Obese Middle-Aged Women

The purpose of this study was to examine the effects of combined exercise training for 16 weeks on obesity indices and artery intima media thickness...

Effect of a High Intensity Interval Training (HIIT) on Serotonin and Cortisol Levels in Obese Women With Sleep Disorders

Background: Physical and physiological changes in obese middle-aged women cause hormonal changes, which are threatening factor for quality of life and health of elderly. Objectives : The purpose of this study was to investigate the effect of a one-week HIIT on serotonin and cortisol levels in obese women with sleep disorders. Methods: The research method was semi-experimental with pre-test post-test design, in which 34 middle-aged obese women with mean age of 47.11 ± 2.3, body mass index of 33.4 ± 2.7, and body fat percentage of 35.8 ± 2.3 were selected based on convenience sampling. Subjects were randomly divided to experimental groups (HIIT exercises) and control group. The experimental group performed a training program for one week, including three sets of RAST protocol (six bouts of 35 meters with 10 seconds of rest between each) with a four-minute rest between each set. Pittsburgh sleep test was used to diagnose sleep disorders (score 11 and above). Actiwatch 8 was used to evaluate quality of sleep in the post-test. In order to to measure the serotonin and cortisol levels, a serotonin kit from the German company LBL and SSGN kit was used, respectively. Independent and dependent t-test were used for data analysis at P ≤ 0.05. Results: The results suggested that cortisol level of HIIT training group was decreased significantly after the exercise intervention (P = 0.01; t = 0.93). On the other hand, the serotonin levels of the HIIT training group was significantly lower (P = 0.001; t = 11.02), while in the control group, the change was not significant (P = 0.15; t = 1.53) and the quality of sleep in the training group was improved significantly (P = 0.001; t = 6.52). Conclusions: In conclusion, HIIT exercises can improve the quality of sleep through hormonal changes and as a result, improve the physiological functions of middle-aged women.

Comparison and analysis of spontaneous cerebrospinal fluid rhinorrhea with and without empty sella patients

Objective:To investigate the clinical characteristics and the diagnosis and treatment of spontaneous cerebrospinal fluid rhinorrhea with and without empty sella.Method: Retrospective analysis clinical data of 51 patients with spontaneous cerebrospinal fluid rhinorrhea，comparison of non-empty sella syndrome of spontaneous cerebrospinal fluid rhinorrhea with empty sella syndrome of spontaneous cerebrospinal fluid rhinorrhea patients with general characteristics，localization and treatment effect.Result:The incidence of spontaneous cerebrospinal fluid rhinorrhea patients was higher in females than in males，BMI index was higher than the normal value.Of these 51 patients，5 of them were discharged after conservative treatment.Endoscopic sinus surgery was performed in 46 cases，of which 4 cases recurred and all had empty sella syndrome，the success rate of surgical repair was 91.3%.The age of empty sella group，the proportion of high blood pressure and the number of patients with surgical recurrence were significantly higher than those in the non-empty sella group（P<0.05）.The defect locations of two groups were most common in the ethmoid roof，there were no statistically significant differences in each defect location （P＞0.05）. Conclusion:The spontaneous cerebrospinal fluid leak was common in obese middle-aged women，most common defect location in ethmoid roof，nasal endoscopic repair success rate was high，with empty sella surgery were more likely to recur.

Effects of exercise using a mobile device on cardiopulmonary function, metabolic risk factors, and self-efficacy in obese women.

The purpose of this study was to determine the effects of a 12-week walking exercise using a mobile device on cardiopulmonary function, metabolic risk factors, and self-efficacy in obese middle-aged women. For this study, 14 middle-aged subjects with obesity were included and performed walking exercise of 50%–60% maximum oxygen uptake intensity 3 times a week for 12 weeks. As a result, weight, % body fat, body mass index, and waist circumference significantly reduced. In addition, systolic blood pressure, diastolic blood pressure, mean arterial pressure, and hemoglobin A1c significantly reduced, while high-density lipoprotein cholesterol and flexibility significantly increased. Furthermore, exercise using a mobile device significantly increased self-efficacy. In conclusion, walking exercise using a mobile device is a good method to constantly increase the exercise participation rate, as it improves metabolic risk factor and obesity index, and increases self-efficacy.

스피닝 운동이 비만중년여성들의 최대산소섭취량과 건강관련체력에 미치는 영향

스피닝 운동이 비만중년여성들의 최대산소섭취량과 건강관련체력에 미치는 영향

순환운동이 비만중년여성들의 활성산소와 총항산화력에 미치는 영향

순환운동이 비만중년여성들의 활성산소와 총항산화력에 미치는 영향

복합운동과 혈청 osteoprotegerin 및 아디포카인의 상관성

Osteoprotegerin (OPG) plays a core role in bone reformation by antagonizing the effect of receptor activator of nuclear factor κ-B ligand (RANKL), and mediates vascular calcification in cardiovascular disease patients. Thus, we aimed to examine the correlations between combined exercise, serum OPG levels and adipokine in obese middle-aged women. 24 obese women (body mass index ≥25 kg/m²) participated in this study and divided into exercise and control (n=12, respectively). Complex training program of aerobic (intensity at 55~75% HRmax, 30 minutes a day) and resistance (intensity at 10~12 RM, 20 minutes a day) for 5 times per week for 8 weeks. Physical measurement, biochemical assay were measured. Serum OPG and leptin, and adiponectin were assessed. After complex training, weight, percent body fat, serum OPG levels, and leptin were significantly decreased, and adiponectin was significantly increased in exercise group. Serum OPG was a significant negative correlation with weight (r=.522, p=.009) and BMI (r=.564, p=.004) in pre, and significant positive correlation with △percent body fat (r=.647, p=.023) in post. In terms of the correlation between weight (β=.522, p=.009) and BMI (β= .564, p=.004) were negative correlation with OPG with 27.3 and 31.8 percent of influence in respectively. △percent body fat (β=.647, p=.023) also showed positive correlation with OPG with 41.9 percent of influence. In conclusion, our study showed that serum OPG levels are correlated with cardiovascular risk factors, such as weight, BMI and percent body fat in obese middle-aged women and adipoline, suggesting that serum OPG has potential as a cardiovascular disease indicator and predictor.

복합운동프로그램이 비만중년여성들의 생활습관병 관련인자와 혈중활성산소에 미치는 영향

Recently, due to lack of physical activity, middle-aged women are exposed to Lifestyle-related diseases by obesity and health care is urgently needed. The purpose of this study was to investigate the effect of complex exercise program on Lifestyle-related factors and blood free oxygen radical of middle-aged obese women. The two-way repeated measure ANOVA was used to verify the difference between the time of measurement and the group. At this time, the paired sample t-test was performed for the variables with statistically significant differences in each variable. The significance level of all results was set to p.05 and the following conclusions were obtained. In the changes of Lifestyle-related factors, the body fat percentage showed an interaction effect between group and period & group. The blood glucose showed only the interaction effect between period & group. Total cholesterol had an interaction effect between timing and period & group, In neutral fat, there was only interaction effect between timing & group. In blood pressure, there was no interaction effect in time, group and time & group. Also in all the factors of the exercise group, the difference between the two groups was statistically significant after the experiments than before. Changes in blood activated oxygen were found to have an interaction effect between the two groups. In the exercise group, statistically significant decrease was observed after the experiment. In conclusion, complex exercise has a positive effect on improving Lifestyle-related factors and blood stress. This indicates that this can be a recommended exercise method for middle-aged obese women. In future follow-up studies, if the exercise duration is prolonged and the intensity is gradually increased, it can be considered to be a program that can prevent various Lifestyle diseases by eliminating middle-aged obesity.

Connecting the dots between breast cancer, obesity and alcohol consumption in middle-aged women: ecological and case control studies

BackgroundBreast cancer (BC) incidence in Australian women aged 45 to 64 years (‘middle-aged’) has tripled in the past 50 years, along with increasing alcohol consumption and obesity in middle-age women. Alcohol and obesity have been individually associated with BC but little is known about how these factors might interact. Chronic psychological stress has been associated with, but not causally linked to, BC. Here, alcohol could represent the ‘missing link’ – reflecting self-medication. Using an exploratory cross-sectional design, we investigated inter-correlations of alcohol intake and overweight/obesity and their association with BC incidence in middle-aged women. We also explored the role of stress and various lifestyle factors in these relationships.MethodsWe analysed population data on BC incidence, alcohol consumption, overweight/obesity, and psychological stress. A case control study was conducted using an online survey. Cases (n = 80) were diagnosed with BC and controls (n = 235) were women in the same age range with no BC history. Participants reported lifestyle data (including alcohol consumption, weight history) over consecutive 10-year life periods. Data were analysed using a range of bivariate and multivariate techniques including correlation matrices, multivariate binomial regressions and multilevel logistic regression.ResultsEcological inter-correlations were found between BC and alcohol consumption and between BC and obesity but not between other variables in the matrix. Strong pairwise correlations were found between stress and alcohol and between stress and obesity.BMI tended to be higher in cases relative to controls across reported life history. Alcohol consumption was not associated with case-control status. Few correlations were found between lifestyle factors and stress, although smoking and alcohol consumption were correlated in some periods. Obesity occurring during the ages of 31 to 40 years emerged as an independent predictor of BC (OR 3.5 95% CI: 1.3–9.4).ConclusionsThis study provides ecological evidence correlating obesity and alcohol consumption with BC incidence. Case-control findings suggest lifetime BMI may be important with particular risk associated with obesity prior to 40 years of age. Stress was ecologically linked to alcohol and obesity but not to BC incidence and was differentially correlated with alcohol and smoking among cases and controls. Our findings support prevention efforts targeting weight in women below 40 years of age and, potentially, lifelong alcohol consumption to reduce BC risk in middle-aged women.

Predicting the development of persistent knee pain and symptomatic knee osteoarthritis among overweight and obese middle-aged women in general practice

Predicting the development of persistent knee pain and symptomatic knee osteoarthritis among overweight and obese middle-aged women in general practice

Predictive value of early structural changes on radiographs and MRI for incident clinical and radiographic knee osteoarthritis in overweight and obese women.

To determine the predictive value of tibiofemoral (TF), patellofemoral (PF) MRI osteoarthritis (OA), and Kellgren and Lawrence grade 1 (KLG1) for the incidence of knee OA (clinical and/or radiological signs) at 2.5 and 6.5 years follow-up in a high-risk cohort. Data of the PROOF study were used, consisting of middle-aged obese women without clinical (ACR-criteria) knee OA and free of radiographic signs (KLG < 2) at baseline. To determine the relation between MRI defined knee OA and KLG1 at baseline with clinical (ACR criteria) or radiographic OA (KLG ≥ 2) at the follow-up points, sensitivity, specificity, likelihood ratios and pre-test and post-test probabilities were calculated. The baseline prevalence of KLG1 (42.9%) was higher than TF MRI OA (14.6%) and PF MRI OA (10.0%). All diagnostic performance statistics indicated better prediction for radiographic OA than for clinical OA. For both outcomes and time points, the absolute difference between pre-test and post-test probabilities was the highest for TF MRI OA. The number needed to screen to obtain a certain number of cases with definite knee OA after a given follow-up period was higher (16-524%) for MRI OA, than for KLG1. When comparing the associations and post-test probabilities, TF MRI OA was more strongly related to the development of radiographic knee OA than KLG1. However, for the selection of people at high risk for developing knee OA, for instance for preventive trials, radiography seems to be sufficient, due to the high baseline prevalence.

Clinical analysis of adult spontaneous cerebrospinal fluid rhinorrhea

To discuss the clinical characteristics, diagnosis and treatment of adult spontaneous cerebrospinal fluid rhinorrhea (CSFR). A retrospective study was conducted on 18 patients of CSFR. Nasal secretion was collected for biochemical analysis. Imaging examination was done for identification of the bony defect in skull base. In all cases, the glucose concentration of nasal secretion were more than 1.7 mmol/L, and the β-2 transferrin detected by immunoelectrophoresis technique were positive. Twelve cases were found to have bony defect in skull base. For the rest 6 cases without bony defect, MRI findings of 6 cases showed sinusoidal effusion with similar signals to cerebrospinal fluid, thus predicting the location of the leak. Conservative treatment was successful in one case, and the other 17 patients underwent endoscopic sinus surgery with computer assisted navigation system (CANS). The results of all cases underwent surgery were successful by one time. No recurrence occured during the follow-up time (11 to 24 months). The incidence of adult CSFR is low, hence it is easily to be missed and misdiagnosed. The majority of CSFR patients are middle-aged and elderly obese women, often combined with hypertension, diabetes, moderate and severe osteoporosis due to no daily exercise habits. Correct medical history collection, reasonable preoperative examination and accurate preoperative localization of bony defect are essential for surgical repairment. CANS used during operation can enable surgeons to locate the site of leakage accurately and shorten the operation time.

Effects of Health Qigong Baduanjin on diabetes related indexes in middle-aged obese women

To investigate the effect of Health Qigong Baduanjin on the related indexes of obese middle aged women with diabetes and to provide new ideas for the intervention treatment of diabetes. A total of 40 middle-aged female obese diabetic patients were randomly divided into the control group and the exercise group(n=20), the age was(57.2±5.4) years old. Fitness training group performed eight new Baduanjin exercises for 24 weeks of intervention, the control group did not exercise, body weight, waist circumference, body mass index (BMI), waist hip ratio (WHR), fasting blood glucose (FPG), glycosylated hemoglobin (HbAlc), triglyceride(TG), total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) levels and serum retinol binding protein 4(RBP4) index were observed in the two groups. After exercise, the waist, WHR, FPG, TG, HbAlc, HDL and RBP4 levels of the the patients in the experimental group were decreased significantly compared with those of before exercise and those of the patients in the experimental control group before and after exercise (P<0.05). Health Qigong Baduanjin can reduce the blood sugar of obese female patients with diabetes, and has some improvement effect on the body part of obesity and blood lipid indicators.

Relationship between plasma protein S levels and apolipoprotein C-II in Japanese middle-aged obese women and young nonobese women.

: Protein S, a nonenzymatic cofactor to activated protein C, presents in two forms in plasma, free form and in a complex with C4b-binding protein. The aim of this study was to determine the association of plasma protein S levels with the variables related to cardiovascular disease risk. The relationships between plasma protein S levels with lipids, inflammation markers, and adiposity were first examined on middle-aged obese women (n = 62), then on young nonobese women (n = 160) to verify the findings in the obese women. Total and free protein S antigen levels in middle-aged obese women, approximately half being in a postmenopausal state and suffered from dyslipidemia, correlated negatively with estradiol and positively with triglycerides, total cholesterol, LDL cholesterol, apoA-II, apoB, apoC-II, apoC-III, apoE, hemoglobin A1c, and protein C, whereas there was no correlation with HDL cholesterol, apoA-I, BMI, visceral fat area, blood pressure, or factor VII activity. Multiple linear regression analyses revealed that protein C, apoC-II, and fibrinogen were significant predictors of total protein S antigen levels, accounting for 51.9% of variance, and apoC-II as a singular significant predictor for free protein S antigen levels (12.3% of variance). In young nonobese women, most being normolipidemic, apoC-II was also selected as a significant predictor of total protein S antigen levels, but not of free protein S antigen levels. The positive relationship between plasma protein S levels and apoC-II, a key regulator of triglycerides hydrolysis, may contribute to the pathogenesis of increased concentrations of plasma protein S.

Effects of Bicycle Exercise on Inflammation Related Factor and Growth Hormone in Obese Middle aged Women

Effects of Bicycle Exercise on Inflammation Related Factor and Growth Hormone in Obese Middle aged Women

Effects of 12-week circuit exercise program on obesity index, appetite regulating hormones, and insulin resistance in middle-aged obese females.

[Purpose] The purpose of this study is to investigate the effects of circuit exercise on obesity index, appetite regulating hormones and insulin resistance in middle-aged obese women. [Subjects and Methods] The subjects of this study were 26 obese middle-aged women who were selected among participants in exercise class at K Region Health Promotion Center in South Korea and were randomly assigned to the exercise group (n=13; age 50.15 ± 3.82, % body fat 38.79 ± 3.28) and the control group (n=13; age 49.84 ± 2.96, % body fat 37.46 ± 2.51). Circuit exercise consisted of aerobic exercise and resistance exercise for 5 weeks and 50 minutes for 12 weeks. Before and after exercise we measured obesity index, leptin, ghrelin, fasting blood glucose, insulin, and insulin resistance in all subjects. A repeated-measured two-way of variance was performed for comparison of the treatment effects between the exercise and control groups. [Results] Body weight, BMI, and body fat percentage of obese index decreased significantly. Leptin of dietary regulation hormone was significantly decreased and ghrelin was significantly increased. Insulin and insulin resistance was significantly decreased. [Conclusion] Circuit exercise can be viewed as an effective exercise program to induce changes in appetite regulating hormones and to improve insulin resistance by mechanisms of energy homeostasis by weight loss.

Effects of combined exercise on inflammatory factors and nitric oxide in obese Middle-Aged women

Effects of combined exercise on inflammatory factors and nitric oxide in obese Middle-Aged women

LIFESTYLE PERCEPTIONS AMONG MIDDLE – AGED OBESE WOMEN

Background. The aim of the study was to establish the perceptions of lifestyles among middle-aged obese women. Methods. Data collection method was semi-structured face-to-face interview. Interview guide was based on short form 36 (SF-36), long form of IPAQ and previous research (Bukman et al., 2014). Results. All obese women of our study feel inferiority complex due to their physical appearance, feel dissatisfied with themselves trying to hide their appearance, discomfort, and disadvantages. They have a lot of health problems: joint pain, increased cholesterol level, increased blood pressure, heart beat rate, dyspnoea, as well as chronic diseases such as type 2 diabetes, thyroid gland dysfunction and sleep disorders. All the subjects both had poor eating habits and ate inadequate food. Some of the participants ate a lot before bedtime and skip breakfast. The physical activity is limited and reduced of all subjects. Conclusions. The relationship between excess weight and psychological well-being is complex, encompassing physical, social and psychological factors. All obese women of our study feel inferiority complex due to their physical appearance, dissatisfied with themselves. They complained of cardiovascular problems, sleep disorders and chronic diseases. The physical activity was limited and decreased. Also, such a great weight excess caused a discomfort in their daily life. Obese women in our study negatively view smoking effects, but they tolerate or even have positive attitudes to alcohol consumption, though they acknowledge that alcohol increases their weight. Malnutrition is most common problem of our respondents. They both had poor eating habits and ate inadequate food. Some of the participants ate a lot before bedtime and skip breakfast. A lot of participants reported about their negative attitude to their diet, but this attitude did not always act like a stimulus to change. Most of respondents could not find the time or motivation to engage in the adequate physical activity. They wanted to increase their physical activity, but found excuses not to do that – their excess of weight, lack of time, as well as laziness, passivity - the main causes of their inactivity or poor physical activity.