1.1. A series of 112 infertile women has been divided into three groups, as a study method, on the basis of the abnormality or relative normality of the endometrium on initial pretreatment biopsy.2.2. The normality and abnormality or inadequacy of their initial pretreatment midcycle cervical mucous specimens has been studied for each endometrial group and related to it, and the mucus has also been studied in those women in each group who subsequently became pregnant and in those who did not, and comparisons have been made.3.3. The findings from this study are: (a) it is more important for an infertile woman to have normal endometrium if she is to eventually attain successful pregnancy than to have normal initial cervical mucus, but both factors play an essential role in the process, (b) more infertile women who have normal cervical mucus become pregnant than do those in whom the mucus is deficient, and (c) there is a relationship between the endometrial and cervical mucus factors in infertile women which may be quantitatively expressed for groups having differing degrees of infertility.
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