Abstract This work presents the design and experimental validation of a high performance, compact, waveguide duplexer operating from 91.5 to 96.5 GHz for its integration in diverse W-band microwave equipment as in plasma diagnosis applications. It uses a single frequency band, with two signals discriminated by different orthogonal circular polarization, which is generated by means of a septum orthomode transducer (OMT) polarizer. Moreover, this component is optimized loaded with the horn antenna for improving the overall system performance. It is explained how these two components are integrated into a very compact duplexer, designed using efficient numerical algorithms. The manufacturing process by mean of high precision milling, and including electrical discharge machining (EDM) has led to excellent performances. The measured return loss level and isolation are higher than 30 dB, and the insertion loss level is below 0.3 dB. Finally, the key parameter in this device, which reflects the symmetry in the manufacturing process, i.e., the axial ratio, is lower than 0.6 dB for both polarizations, an excellent result showing the potential of the presented design.