You have accessJournal of UrologySexual Function/Dysfunction: Basic Research & Pathophysiology II1 Apr 2016MP89-13 DIAGNOSTICS OF PENILE MICROCIRCULATION DISORDERS IN PATIENTS WITH VASCULOGENIC ERECTILE DYSFUNCTION Dmitry Kurbatov, Roman Aliev, and Ruslan Aliev Dmitry KurbatovDmitry Kurbatov More articles by this author , Roman AlievRoman Aliev More articles by this author , and Ruslan AlievRuslan Aliev More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2474AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Duplex Doppler ultrasonography (DDU) is the conventional test for penile haemodynamic evaluation for erectile dysfunction (ED) screening. We used since 2007 a new method for vasculogenic ED diagnosis - Laser Doppler Microcirculation Floumetry (LDMF). METHODS Ninty six patients were examined – 69 men (mean age 56±5,2) suffered arteriovenous form of ED and 27 healthy men (mean age 28±4,6) as control group. Patients with diabetes mellitus, severe arterial hypertension were excluded. Initially all men undergone DDU with pharmacological test, then tested by LDMF with laser analyzer LAKK-02 («LAZMA», Russia) and helium-neon laser of LGN-207 B-type with 0,63 microns wave length. RESULTS Slow rhythms with frequency of 1-10 oscillations per minute prevailed in the control group. These rhythms were accompanied with the maximum intravascular resistance and active microcirculations mechanism. We considered these blood flow parameters as a physiological norm of the peripheral microcirculation and it correlated with the dynamics fluctuations of the blood flow. The patients with ED had intravascular circulatory injuries. It characterized by abrupt decrease of the blood flow and statistically significant fluctuations of the erythrocytes velocity, decreasing of the myogenic tone and increasing of the neurogenic tone in the precapillary net. The microcirculation’s effectiveness index was also decreased. There were the decreasing of the blood perfusion intensity in cavernous tissue, blood volume reduction in the arterioles, and the congestion in venules with increasing of the erythrocytes amount. These data indicated that the patients with vasculogenic ED had the spastic form of microcirculation injure - decreasing of blood inflow due to cavernous tissue vessels spasm. In these cases the microcirculation index and sphygmic fluctuations amplitude decreased, but the slow oscillations amplitude and vasomotory activity increased. CONCLUSIONS LDMF is a new method of vasculogenic ED diagnosis. In comparison with DDU this method allows to check the microcirculation mechanism and evaluate blood flow disturbances directly in the cavernous tissue. It helps to study the pathogenic changes caused by vasculogenic ED and thus improves the quality of diagnosis. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e1141 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Dmitry Kurbatov More articles by this author Roman Aliev More articles by this author Ruslan Aliev More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...