This paper will discuss a portable microcomputer based data acquisition system for toxicology research. The data acquisition system and the companion data base were designed and built by a team of individuals at Battelle, which consisted of Barry Brownstein, Jack Webb, Robert Weiner, and myself. The remainder of this paper will describe the factors which affected the design of the system, as well as details regarding the system's implementation. We will first examine the motivation for such a system.