Shell Microcapsules Research Articles

Timed-Release Silica Microcapsules for Consistent Fragrance Release in Topical Formulations

Microcapsules are widely utilized in various applications to preserve active ingredients for prolonged durations while enabling controlled release. However, limited release of active ingredients often hampers their effectiveness in daily-use products. In this study, we demonstrated the synthesis of silica core–shell microcapsules designed for controlled fragrance release in topical formulations. The microcapsules were synthesized via the sol–gel polymerization of tetraethyl orthosilicate (TEOS) on the surface of an oil/water emulsion, leveraging the shrinkage and deformation characteristics of sol–gel-derived silica during drying. The concentrations of dipalmitoylethyl dimethylammonium chloride, a cationic emulsifier used in cosmetics, and TEOS were optimized to sustain fragrance release for up to 24 h after topical application. An additional silica coating on the microcapsules reduced the Brunauer–Emmett–Teller surface area by 76.54%, enhancing fragrance stability for long-term storage. The timed-release behavior was assessed using fragrance evaluation tests and gas chromatography–mass spectrometry. The fragrance intensity and release profiles confirmed the potential of these microcapsules in daily-use cosmetics. These findings suggest that silica microcapsules with extended-release properties have application potential in both cosmetic and pharmaceutical products.

Homeostatic Microfiber-Composed Synthetic Leathers with Chemical Robustness and Undercooling Self-Regulation.

Homeostatic microfiber leathers with temperature self-regulation promise broad applications, ranging from the apparel and automotive interior industries to the home furnishing and healthcare industries. Temperature self-regulation is achieved by phase-change materials containing microcapsules introduced within the leathers. The introduction of phase change microcapsules (PCMs) into microfiber leather faces two formidable challenges: (1) the shell of microcapsules must remain chemically stable against alkalis and organic solvents; (2) PCMs possess the ability to reduce supercooling during which latent heat is released, allowing for the precise and controllable release of latent heat. Here we present a high-performance homeostatic microfiber-composed synthetic leather containing PCMs that can address these two challenges, which not only demonstrate exceptional chemical robustness under alkaline conditions but also offer efficient and precise control over temperature fluctuation and latent heat release by reducing supercooling. Titanium carbide (TiC) known for its high thermal conductivity and alkali resistance has been selected as the shell material for the microcapsules, which can effectively resolve chemical stability issues. Meanwhile, the high thermal conductivity of TiC can be leveraged to enhance heterogeneous nucleation, thus narrowing the temperature range for latent heat release. The resultant microfiber leather shows outstanding capabilities for adjustable thermal energy storage. Our studies offer an effective approach to create homeostatic microfiber-composed synthetic leathers with chemical robustness and undercooling self-regulation, which would be useful in the fields of the textile, biomedical, and healthcare industries.

Electromagnetic wave absorption and enhanced mechanical properties of magnetic self-healing metal shell microcapsules filled polymer

In this work, PUF/PU@IPDI (PPI) polymer shell microcapsules were synthesized through interfacial polymerization and in situ polymerization. Subsequently, a layer of metal Ni was plated on the surface of microcapsules to fabricate Ni/PUF/PU@IPDI (NPPI) composites. The results revealed that NPPI microcapsules exhibited superior thermal stability and mechanical properties, and NPPI-60 obtained the greatest strength (102.8 MPa). The minimum reflection loss (RL) value of the NPPI-20 composite was up to −32.8 dB at 5.5 mm and the corresponding effective absorption bandwidth (EAB) was 2.4 GHz. Additionally, the NPPI-10 composite displayed the highest healing efficiency (78.6 % and 86.6 % for the scratch depth and width, respectively), and the mechanical strength and fracture toughness of epoxy resin were enhanced by the addition of metal microcapsules. The core-shell structure established by electroless plating can endow self-healing microcapsules with outstanding mechanical characteristics as well as good wave absorption capability, indicating that NPPI composites have promising applications in the field of electromagnetic wave absorption and function and structure integration design of composites.

Corked Microcapsules Enabling Controlled Ultrasound-Mediated Protein Delivery.

While ultrasound represents a facile, portable, and noninvasive trigger for drug delivery vehicles, most reported ultrasound-triggered drug delivery vehicles predominately present "burst" release profiles that are hard to control after the initial activation stimulus. Herein, we report a submerged electrospraying technique to fabricate protein-loaded microcapsules in which silica "corks" are embedded within the microcapsule shell. Upon the application of an ultrasound trigger, the corks can be perturbed within the shell, allowing for the release of the protein payload through a phantom tissue mimic to a degree proportional to the number/time of pulses applied. Specifically, multiple ultrasound pulses were shown to enable a 15- to 23-fold increase in the rate of release of the model bovine serum albumin protein payload relative to no ultrasound being applied, with release returning to a lower level when the ultrasound stimulus was removed. Coupled with the low cytotoxicity of the vehicle components, the corked microcapsules show promise for expanding the potential to use ultrasound to facilitate both on-demand and pulsatile release profiles.

Effect of pH Value on the Structure and Properties of n-Eicosane@Melamine Urea-Formaldehyde Phase Change Microcapsules

In this article, n-eicosane@MUF phase change microcapsules were prepared by in-situ polymerization with n-eicosane as the core material and melamine urea-formaldehyde (MUF) resin as the shell material. The effects of pH values from 3.5 to 6.0 on the surface morphology, particle size distribution, latent heat of phase transformation, encapsulation degree, thermal stability, and permeability resistance of the microcapsules were investigated. The results showed that the surfaces of the microcapsules gradually became smooth with the increase of pH value, and their encapsulation degree and impermeability also increased roughly. When the pH = 5.5, the particle size of the microcapsule samples ranged from 1.5 to 9.7 μm, the melting enthalpy was 178.8 J/g, and the encapsulation degree was 86.6%, which had the best thermal stability and impermeability. However, when the pH = 6.0, the phenomenon of microcapsule shell rupture occurred and the above performance no longer occurred.

Magnetic Phase-Change Microcapsules with High Encapsulation Efficiency, Enhancement of Infrared Stealth, and Thermal Stability

Due to energy shortages and the greenhouse effect, the efficient use of energy through phase-change materials (PCMs) is gaining increased attention. In this study, magnetic phase-change microcapsules (Mag-mc) were prepared by suspension polymerization. The shell layer of the microcapsules was formed by copolymerizing methyl methacrylate and triethoxyethylene silane, with the latter enhancing the compatibility of the shell layer with the magnetic additive. Ferric ferrous oxide modified by oleic acid (Fe3O4(m)) was added as the magnetic additive. Differential scanning calorimetry (DSC) testing revealed that the content of phase-change materials in microcapsules without and with ferric ferrous oxide were 79.77% and 96.63%, respectively, demonstrating that the addition of Fe3O4(m) improved the encapsulation efficiency and enhanced the energy storage ability of the microcapsules. Laser particle size analysis showed that the overall average particle sizes for the microcapsules without and with ferric ferrous oxide were 3.48 μm and 2.09 μm, respectively, indicating that the incorporation of magnetic materials reduced the size and distribution of the microcapsules. Thermogravimetric analysis indicated that the thermal stability of the microcapsules was enhanced by the addition of Fe3O4(m). Moreover, the infrared emissivity of the microcapsule-containing film decreased from 0.77 to 0.72 with the addition of Fe3O4(m) to the shell of microcapsules.

Double-layered phase change material microcapsules with enhanced solar thermal conversion performance and fire safety for buildings

Building energy saving is directly related to resource utilization optimization and residential comfort, which is important for the environment and production. At present, building energy saving is developing towards green, recyclable, and low-risk directions. Phase change materials, as effective energy storage materials, can pollution-freely regulate room temperature. Regarding the leakage, phase change materials are encapsulated into microcapsules. However, the flammability and slow thermal response of phase change material microcapsules hinder their application in building materials. Herein, novel double-layered phase change material microcapsules (D-MPCMs), with the inner poly melamine tetramethylene phosphonium sulfate (PMTMPS) shell layers and outer polydopamine (PDA) shell layers, are prepared by in-situ polymerization method, which are filled into epoxy resin (EP) coatings. This study is the first to use cross-linked flame retardants as the shells of microcapsules. The outer PDA shell layer improves the flame retardancy of microcapsules while overcoming the problem of slow thermal response rate. Thermogravimetric analysis and differential scanning calorimeter tests are considered to explore the thermal stabilities and properties of the resultant microcapsules. Results demonstrate that D-MPCMs have a residual mass of 10.8 % more at 600 ℃ and a faster thermal response rate. The study shows that the addition of the PDA shell layers not only reduces the total heat release from 64.29 MJ/m2 to 45.01 MJ/m2 but also enhances the solar thermal conversion performance which gives potential in the process solar energy storage design and fire safety design in actual building application of epoxy resin coatings.

Effect of thermal processing on the integrity of polyurea microcapsules for underwater adhesives

Adhesives that rely on a curing mechanism struggle to function in underwater environments due to detrimental interactions with water. One strategy to overcome this involves protecting sensitive components in mechanically responsive microcapsules. In this way, a two-part adhesive can be achieved via a single mixture, applied as one would apply a pressure sensitive adhesive. This work focused on improving polyurea microcapsule shell integrity, specifically focusing on the effect of additional thermal processing. The improved microcapsule shells displayed limited payload leakage with only an 8 % loss in pot life compared to the base isocyanate resin alone. A mixture of optimized microcapsules and isocyanate resin was evaluated against a wide range of substrates and conditions, including dry and wet environments. When microcapsules were intentionally ruptured to release the catalyst and crosslinker payload, the microcapsule-isocyanate mixture had improved adhesive strength (506 %) compared to the base isocyanate resin without microcapsules.

Photoactivated Cyclic Polyphthalaldehyde Microcapsules for Payload Delivery.

Microcapsules with a cyclic polyphthalaldehyde (cPPA) shell and oil core were fabricated by an emulsification process. The low ceiling temperature cPPA shell was made phototriggerable by incorporating a photoacid generator (PAG). Photoactivation of the PAG created a strong acid which catalyzed cPPA depolymerization, resulting in the release of the core payload, as quantified by 1H NMR. The high molecular weight cPPA (197 kDa) yielded uniform spherical microcapsules. The core diameter was 24.8 times greater than the cPPA shell thickness (2.4 to 21.6 μm). Nonionic bis(cyclohexylsulfonyl)diazomethane (BCSD) and N-hydroxynaphthalimide triflate (HNT) PAGs were used as the PAG in the microcapsule shells. BCSD required dual stimuli of UV radiation and post-exposure baking at 60 °C to activate cPPA depolymerization while room temperature irradiation of HNT resulted in instantaneous core release. A 300 s UV exposure (365 nm, 10.8 J/cm2) of the cPPA/HNT microcapsules resulted in 66.5 ± 9.4% core release. Faster core release was achieved by replacing cPPA with a phthalaldehyde/propanal copolymer. A 30 s UV exposure (365 nm, 1.08 J/cm2) resulted in 82 ± 13% core release for the 75 mol % phthalaldehyde/25 mol % propanal copolymer microcapsules. The photoresponsive shell provides a versatile polymer microcapsule technology for on-demand, controlled release of hydrophobic core payloads.

Nanoparticle‐Empowered Core–Shell Microcapsules: From Architecture Design to Fabrication and Functions (Small 33/2024)

Nanoparticle‐Empowered Core–Shell Microcapsules: From Architecture Design to Fabrication and Functions (Small 33/2024)

Current Challenges in Microcapsule Designs and Microencapsulation Processes: A Review.

Microencapsulation is an advanced methodology for the protection, preservation, and/or delivery of active materials in a wide range of industrial sectors, such as pharmaceuticals, cosmetics, fragrances, paints, coatings, detergents, food products, and agrochemicals. Polymeric materials have been extensively used as microcapsule shells to provide appropriate barrier properties to achieve controlled release of the encapsulated active ingredient. However, significant limitations are associated with such capsules, including undesired leaching and the nonbiodegradable nature of the typically used polymers. In addition, the energy cost of manufacturing microcapsules is an important factor to be considered when designing microcapsule systems and the corresponding production processes. Recent factors linked to UN sustainability goals are modifying how such microencapsulation systems should be designed in pursuit of "ideal" microcapsules that are efficient, safe, cost-effective and environmentally friendly. This review provides an overview of advances in microencapsulation, with emphasis on sustainable microcapsule designs. The key evaluation techniques to assess the biodegradability of microcapsules, in compliance with recently evolving European Union requirements, are also described. Moreover, the most common methodologies for the fabrication of microcapsules are presented within the framework of their energy demand. Recent promising microcapsule designs are also highlighted for their suitability toward meeting current design requirements and stringent regulations, tackling the ongoing challenges, limitations, and opportunities.

Preparation of polyurethane shell microcapsules containing isocyanate core by Pickering emulsion method using modified silica nanoparticles and investigation of their self-healing performance

Encapsulating repair agents are increasingly popular for repairing coating damage, with capsules being a common method to address surface scratches by releasing healing liquid into the fissure. However, creating microcapsules that are durable against environmental factors remains a key concern. Current research focuses on advancements in encapsulating healing agents and their production methods, particularly emphasizing the integration of capsules into coatings for external self-healing purposes. Polyurethane capsules containing isophorone diisocyanate were synthesized using the Pickering emulsion method with modified silica as a Pickering emulsion stabilizer in three different percentages and then dispersed in urea formaldehyde at varying weight percentages. The self-healing properties of this coating were then studied. Fourier transform infrared spectroscopy (FTIR), Soxhlet extraction, and thermogravimetric analysis (TGA) were performed on the samples to ensure the success of the encapsulation process. The morphology of the capsules was investigated using field emission scanning electron microscopy (FE-SEM), revealing that the synthesized capsules possess a spherical shape and are adequately spaced apart. These capsules were spherical at micron scales, with differences observed based on the quantity of stabilizing nanoparticles employed. Furthermore, the capsules demonstrated robust thermal stability, as evidenced by the increase in IPDI evaporation temperature from approximately 140 °C to 240 °C.Immersion test results in saltwater solutions showed that coatings containing pickering capsules exhibited better corrosion resistance, further validating the success of the research. The shell strength of the capsules prepared using the Pickering method was increased, enhancing the stability of the microcapsules during the mixing process with the resin and demonstrating self-healing properties. These findings have significant practical implications, as they demonstrate the potential to improve the durability and lifespan of coatings in various applications.

Hybrid Self‐Repairing Polymer Composites Based on a Mixture of Intrinsic and Extrinsic Self‐Healing

AbstractThe development of high‐strength and multiple self‐healing polymer materials remains a major challenge. In this study, a hybrid self‐healable polymer using the combination of intrinsic and extrinsic self‐healing is demonstrated. The epoxy resin microcapsules with dynamic disulfide bonded shells are successfully prepared through an interfacial polymerization method, which are then added into the intrinsically self‐healable epoxy resin substrate also containing disulfide bonds. The unique combination structure enables the polymer composites to exhibit high mechanical strength and excellent multiple self‐healing efficiency. On the one hand, the Young's modulus and tensile strength of the material are enhanced due to the reinforcement effect of the fillers. On the other hand, the extrinsic self‐healing strategy of the microcapsules, which released repair agents, can support the intrinsic repairing substrate to improve the self‐healing ability of the material. More interestingly, the design of the disulfide bond structure of the microcapsule shell contributes to the high self‐healing capability of the material during multiple self‐healing processes.

Study on the Repair Effect of Self-Healing Cementitious Material with Urea-Formaldehyde Resin/Epoxy Resin Microcapsule

Recent studies on microencapsulated self-healing cementitious materials have primarily focused on the particle size and preparation methods of the microcapsules. However, there has been limited attention paid to the microscopic aspects, such as the selection of curing agents and the curing duration of these materials. In this study, urea-formaldehyde resin/epoxy resin E-51 microcapsules were synthesized through in situ polymerization. This research investigates the feasibility of self-healing from a molecular mechanism perspective and evaluates the repair performance of microencapsulated self-healing cement mortar with varying microcapsule concentrations, curing agent types, and curing ages. The findings demonstrate that the microcapsule shells bond effectively with the cementitious matrix, with radial distribution function peaks all located within 3.5 Å. The incorporation of microcapsules enhanced the tensile strength of the modified cement mortar by 116.83% and increased the failure strain by 110%, indicating improved adhesion and mechanical properties. The restorative agent released from the microcapsule core provided greater strength after curing compared to the uncured state. Although the overall strength of the microencapsulated self-healing cement mortar decreased with higher microcapsule concentrations, the repair efficiency improved. The strength recovery rate of 28-day aged modified cement mortar had a significant improvement with the addition of X and Y curing agents, respectively.

Preparation of Graphene Oxide/Polymer Hybrid Microcapsules via Photopolymerization for Double Self-Healing Anticorrosion Coatings.

In this work, graphene oxide (GO)/polymer hybrid microcapsule-loaded self-healing agents were prepared via the combination of the emulsion template method and photopolymerization technology. The incorporation of GO in the microcapsule shell not only improved the impermeability, mechanical property, and solvent resistance property of the microcapsules significantly but also endowed the microcapsules with photothermal conversion property. By incorporating GO/polymer hybrid microcapsules in water-borne epoxy resin, a novel kind of anticorrosion coating with a double self-healing property was successfully fabricated. When the coating was scratched, the linseed oil (LO) encapsulated in the microcapsules could fill the crack, and the photothermal conversion property of GO could promote the molecular chain movement of the damaged area under near-infrared (NIR) irradiation to realize the close of the crack. Based on the filling of LO and photothermal conversion-induced scratch narrowing, the "filling" and "close" double self-healing effect can be realized under temporal NIR irradiation, which could lead to the complete recovery of the scratched coating. The |Z|f=0.1Hz value of the damaged coating with GO/polymer microcapsules after double healing was comparable to that of the intact coating, which was about 4 orders of magnitude higher than that of the scratched blank coating and single self-healing coating. As to the neutral salt spray test, the scratched blank coating failed in protection after 100 h, while the healed composite coating did not show any corrosion after 300 h.

Antioxidant efficacy of amino acids on vitamin A palmitate encapsulated in OSA-starch electrosprayed core-shell microcapsules

The encapsulation and the oxidative stability of vitamin retinyl palmitate (AP), a vitamin A derivative, within coaxial electrosprayed (AP) core – octenyl succinic anhydride (OSA-modified starch) shell microcapsules were investigated. The antioxidant efficiency of amino acids (AAs) (namely histidine, leucine, valine, tryptophan, tyrosine, cysteine and lysine) added to the core, on the oxidative stability of AP was evaluated using differential scanning calorimetry at the isothermal temperature of 140 °C. Confocal microscopy confirmed the location of the AP within the core with AAs microcapsules, surrounded by the shell layer of OSA starch. Scanning electron microscopy revealed that the microcapsules are uniform in size with an average diameter ranging from 2.06 ± 1.05 to 2.41 ± 1.42 μm. The AAs contributed substantially to enhance the oxidative stability of AP, with histidine being the most efficient with an improvement in oxidative stability of about 214 times, while lysine showed the lowest protection (about 3.9 times), compared to non-encapsulated AP. For the encapsulated AP, the presence of histidine or lysine enhanced the oxidative stability of the vitamin by about 70.6 or 1.3 times, respectively. The enhancement of the oxidative stability was mainly due to both the hydrophobic interactions formed between AP and AAs, and the adsorption of AP on the surface of AAs crystals (except lysine), assisted by the suspension of the AAs in ethanol antisolvent, as confirmed with attenuated total reflection–Fourier transform infrared (ATR–FTIR) and X-ray diffraction (XRD) analyses.

Tribological Properties of Polytetrafluoroethylene (PTFE)/Aramid Fabric Composite Liner Modified by PAO40/Polysulfone/SiO2 Hybrid Shell Microcapsules

Hybrid shell microcapsules have been incorporated into polytetrafluoroethylene (PTFE)/aramid fabric composite liners to enhance the tribological behavior of self-lubricating spherical plain bearings. PAO40/polysulfone/SiO2 hybrid shell microcapsules were synthesized utilizing a combination of Pickering emulsification technology and solvent evaporation. The modified liner with 9 wt% microcapsules exhibited the highest reduction in the average friction coefficient and wear rate, which were 31.1% and 47.9% lower than the unmodified liner. Furthermore, the tribological behavior of modified liners was investigated under different loads and sliding speeds. The friction process of the modified liner and the formation process of the transfer film were analyzed. Investigations into the friction reduction mechanism revealed that the PAO-40# released from microcapsules transitioned the friction type from dry to mixed. SiO2 particles are conducive to forming a denser transfer film by the PTFE abrasive. The results of this study have important scientific significance.

Cytotoxic Effects of Doxorubicin on Cancer Cells and Macrophages Depend Differently on the Microcarrier Structure.

Microparticles are versatile carriers for controlled drug delivery in personalized, targeted therapy of various diseases, including cancer. The tumor microenvironment contains different infiltrating cells, including immune cells, which can affect the efficacy of antitumor drugs. Here, prototype microparticle-based systems for the delivery of the antitumor drug doxorubicin (DOX) were developed, and their cytotoxic effects on human epidermoid carcinoma cells and macrophages derived from human leukemia monocytic cells were compared in vitro. DOX-containing calcium carbonate microparticles with or without a protective polyelectrolyte shell and polyelectrolyte microcapsules of about 2.4-2.5 μm in size were obtained through coprecipitation and spontaneous loading. All the microstructures exhibited a prolonged release of DOX. An estimation of the cytotoxicity of the DOX-containing microstructures showed that the encapsulation of DOX decreased its toxicity to macrophages and delayed the cytotoxic effect against tumor cells. The DOX-containing calcium carbonate microparticles with a protective polyelectrolyte shell were more toxic to the cancer cells than DOX-containing polyelectrolyte microcapsules, whereas, for the macrophages, the microcapsules were most toxic. It is concluded that DOX-containing core/shell microparticles with an eight-layer polyelectrolyte shell are optimal drug microcarriers due to their low toxicity to immune cells, even upon prolonged incubation, and strong delayed cytotoxicity against tumor cells.

Environmentally friendly calcium carbonate-polydopamine microcapsules with superior mechanical, barrier, and adhesive properties

There is a rising need to deliver perfume molecules to fabric surfaces during washing cycles to enhance consumers' perception. With upcoming regulations phasing out intentionally produced microplastics by 2027, the focus is on sustainable alternatives to conventional non-biodegradable synthetic microcapsules (e.g. melamine-formaldehyde). Calcium carbonate (CaCO3) has shown promise to form the microcapsule shells due to its environmental benignity, inexpensiveness, and potential for liquid formulations, particularly detergents. Notwithstanding, its inherent porosity undermines the performance of the ensuing microcapsules. Bio-inspired by the adhesive properties of mussel proteins, dopamine is proposed for forming a protective organic coating on CaCO3-based microcapsules. This research aims towards developing primary microcapsules with CaCO3 shells encapsulating hexylsalicylate (HS) as a perfume oil, applying a polydopamine (PDA) coating via oxidative auto-polymerisation of dopamine-hydrochloride (pH 8.5), and conducting a comprehensive analysis of morphological, mechanical, barrier, and adhesive properties through advanced techniques, namely fluorescent-sensing/scanning electron microscopy (SEM), micromanipulation, UV–Vis spectrometry, and a microfluidic chamber fitted with polyethylene-terephthalate (PET) fabrics. The obtained microcapsules (D[3, 2]=31.2 ± 0.4 μm) exhibited a spherical core-shell structure with a smooth PDA-coated surface. Mechanical assessments reveal remarkable rupture stress (2.2 ± 0.3 MPa) comparable to that of commercial microcapsules. After one month in water, ∼40% of HS was released from PDA-coated microcapsules, while the primary ones released the entire amount within 4 h. When mimicking washing conditions (pH 9), the PDA-coated microcapsules demonstrated improved retention (∼60%) on the PET substrate at hydrodynamic shear stress of ∼1 Pa, whereas that of the primary microcapsules was below 10%. Overall, this study suggests the successful fabrication of eco-friendly microcapsules featuring a hybrid inorganic-organic shell, with enhanced mechanical strength, reduced leakage, and improved adhesion, showcasing their potential in applications within the fast-moving consumer goods industry.

Characterization of Polyallylamine/Polystyrene Sulfonate Polyelectrolyte Microcapsules Formed on Solid Cores: Morphology.

Polyelectrolyte microcapsules (PMC) based on polyallylamine and polystyrene sulfonate are utilized in various fields of human activity, including medicine, textiles, and the food industry, among others. However, characteristics such as microcapsule size, shell thickness, and pore size are not sufficiently studied and systematized, even though they determine the possibility of using microcapsules in applied tasks. The aim of this review is to identify general patterns and gaps in the study of the morphology of polyelectrolyte microcapsules obtained by the alternate adsorption of polystyrene sulfonate and polyallylamine on different solid cores. First and foremost, it was found that the morphological change in polyelectrolyte microcapsules formed on different cores exhibits a significant difference in response to varying stimuli. Factors such as ionic strength, the acidity of the medium, and temperature have different effects on the size of the microcapsules, the thickness of their shells, and the number and size of their pores. At present, the morphology of the microcapsules formed on the melamine formaldehyde core has been most studied, while the morphology of microcapsules formed on other types of cores is scarcely studied. In addition, modern methods of nanoscale system analysis will allow for an objective assessment of PMC characteristics and provide a fresh perspective on the subject of research.