Microbiological Oxidation Research Articles

THE OXIDATION OF SOME TERMINAL-SUBSTITUTED POLYHYDRIC ALCOHOLS BY ACETOBACTER SUBOXYDANS

Various terminal-substituted pentitols and hexitols, which possessed either the L-lyxo- or the D-ribo-configuration at the three contiguous carbon atoms adjacent to the terminal carbon atom, were oxidized to ketoses by Acetobactersuboxydans. The terminal hydroxyl group of the polyol was replaced by -H, -OMe, -SEt, and -OAc groups; several 1,1-dithioacetal derivatives of aldoses were also tested. The preparation of 1-O-acetyl-DL-galactitol, 1-deoxy-1-S-ethyl-D-arabitol, and 6-deoxy-6-S-ethyl-L-sorbose are described. 6-Deoxy-6-S-ethyl-L-sorbose was prepared by the microbiological oxidation of 1-deoxy-1-S-ethyl-D-glucitol.

Microbiological Oxidations of Reichstein's Compound S by Corticium solani

Microbiological Oxidations of Reichstein's Compound S by Corticium solani

The microbiological oxidation of cholesterol

The oxidative degradation of cholesterol by a mycobacterium has been studied. The steroid molecule is attacked by the simultaneous action of molecular oxygen and enzymic oxidation. A number of CO and OH groups is introduced at different carbon atoms of the skeleton and side chain. Methods for the separation, isolation and partial identification are described.

Sulphur and nitrogen changes in forest soils of East Africa

Sulphur measurements made on soils in East Africa revealed the unexpected occurrence of sulphates in forest subsoils. Soil profiles from plantation and natural forests were analysed and a general pattern of sulphur distribution was found. It has been found that in addition to the sulphur cycle dependent upon microbiological oxidation of organic sulphur there exists a cycle whereby sulphate is circulated as such between trees and soil. The biological oxidation of organic sulphur in the soil is an extremely slow process compared with that of carbon and nitrogen. Treatment with calcium carbonate, nitrates and non-sulphur-containing amino acids had no effect upon the subsequent sulphate production. Incubation with either S-containing amino acids or with calcium sulphate however, resulted in an increased rate of soil-sulphur oxidation and this effect is being further investigated. An aqueous extract of wattle leaves proved to inhibit nitrification in the soil for short periods and evidence is presented which suggests that methionine may be involved in this effect.

Microbiological degradation of cholic acid.

FOR the microbiological oxidation of cholic acid, two possible pathways different from that found in A. faecalis1 or E. coli2 can be suggested.

Steroidal sapogenins. XXXII. Attempted microbiological oxidation

Steroidal sapogenins. XXXII. Attempted microbiological oxidation

ステロイドの研究 (第5報)

In accordance with the method of Vischer and Wettstein, microbiological oxidation of progesterone (I) was examined by using Fusarium solani. It was thereby found that, according to the amount of (I) used and the addition or absence of acetone, the following products would be formed in various ratios: 1-Dehydroprogesterone (II), Δ1, 4-androstadien-17 β-ol-3-one (III), Δ1, 4-androsta-diene-3, 17-dione (IV), and 1-dehydrotestololactone (V). From the foregoing experimental results, it was assumed that the present reaction proceeded in the order of (I)→(II)→(III)→(IV)→(V).

Studies of the microbiological oxidation of steroids by Cunninghamella blakesleeana H-334. I. The effect of alcohols and phenol.

Studies of the microbiological oxidation of steroids by Cunninghamella blakesleeana H-334. I. The effect of alcohols and phenol.

Studies of the microbiological oxidation of steroids by Cunninghamella blakesleeana H-334. II. Medium design.

Studies of the microbiological oxidation of steroids by Cunninghamella blakesleeana H-334. II. Medium design.

Studies of the Microbiological Oxidation of Steroids by Cunninghamella blakesleeana H-334

Studies of the Microbiological Oxidation of Steroids by Cunninghamella blakesleeana H-334

Studies of the Microbiological Oxidation of Steroids by Cunninghamella blakesleeana H-334

Studies of the Microbiological Oxidation of Steroids by Cunninghamella blakesleeana H-334

Microbiological oxidation of ammonium and thiocyanate ions in soil.

AMMONIUM sulphate1 and sodium thiocyanate2, when perfused through chalked soils neutralized by calcium carbonate, are metabolized by the growth of specific groups of soil microflora on the soil crumb surface to nitrate and ammonium sulphate respectively.

Microbiological Oxidation of Sterols

IN an earlier communication1 we stated that by cultivating Proactinomyces roseus in a synthetic culture medium in which the only source of carbon and nitrogen was 2 per mille pyridine, and using up the superfluous nitrogen by emulsifying 0·1 per cent cholesterol in the medium and aerating it at 34° C., in two weeks we obtained 7-oxycholesterol and 4,5-cholestonone. Later, we received a letter from Dr. G. A. D. Haslewood, of the Physiological Laboratory, Guy's Hospital, London, S.E., expressing doubt that the occurrence of 7-oxycholesterol was the result of the microbiological oxidation; in his opinion, the result was analogous to the production of 7-oxycholesterol from cholesterol in alkali medium, by aeration and elevated temperature, as shown by Bergstrom and Wintersteiner2,3, in which case the micro-organism plays no part.

Microbiological Oxidation of Cholesterol with Azotobacter

L. Mamoli and A. Vercellone1 were the first to work with the microbiological oxidation of sterols. They carried out investigations principally in a series of sex hormones, and with the aid of Coryne-bacteria, cultivated together with yeast, oxidized steroid alcohols to ketones. Recently, G. E. Turfitt2 found identical results with certain species of Proactinomyces.

The formation of hyponitrous acid as an intermediate compound in the biological or photochemical oxidation of ammonia to nitrous acid

Research Article| May 01 1935 The formation of hyponitrous acid as an intermediate compound in the biological or photochemical oxidation of ammonia to nitrous acid: Microbiological oxidation1 Alexander Steven Corbet Alexander Steven Corbet 1The I.C.I. Agricultural Research Station, Jealotts Hill, Bracknell, Berks Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1935) 29 (5): 1086–1096. https://doi.org/10.1042/bj0291086 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation Alexander Steven Corbet; The formation of hyponitrous acid as an intermediate compound in the biological or photochemical oxidation of ammonia to nitrous acid: Microbiological oxidation. Biochem J 1 May 1935; 29 (5): 1086–1096. doi: https://doi.org/10.1042/bj0291086 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1935 CAMBRIDGE UNIVERSITY PRESS1935 Article PDF first page preview Close Modal You do not currently have access to this content.