Micro-plasma Radio-frequency Technology Research Articles

Betamethasone transdermal administration combined with fractional Er:YAG lasers or microplasma radiofrequency technology improved hypertrophic scars: A retrospective study.

This retrospective study aims to compare the efficacy rates in treating hypertrophic scars among four distinct groups of patients who either underwent fractional Erbium: yttrium-aluminum-garnet (Er:YAG) laser or microplasma radiofrequency technology as standalone treatments or in combination with compound betamethasone transdermal administration. The study retrospectively examined 208 patients treated at our institution from April 2011 to December 2022 for hypertrophic scars, receiving no less than three treatments (with an interval of 8 weeks between each). The patients were categorized into four groups: the F group (treated with fractional Er:YAG laser), the F + B group (treated with fractional Er:YAG laser combined with compound betamethasone transdermal administration), the P group (treated with microplasma radiofrequency technology), and the P + B group (treated with microplasma radiofrequency technology combined with compound betamethasone transdermal administration). The therapeutic effects were evaluated based on the changes in the Vancouver Scar Scale (VSS) scores before and after treatment in these groups. There was no statistically significant difference in the VSS scores among the four groups before treatment. After undergoing three sessions of the aforementioned four types of treatment, all groups showed a decrease in VSS scores, with average posttreatment VSS scores for the F group scored 5.15 ± 2.084, F + B group scored 3.7 ± 1.781, P group scored 4.41 ± 1.933, and P + B group scored 3.16 ± 1.775, respectively. With an increasing number of treatments, the total effective rate gradually increased in all four groups, and the combination treatment using compound betamethasone transdermal administration proved more effective than the standalone treatment. All four treatments yielded favorable outcomes, with the combined therapy involving compound betamethasone transdermal administration proving more effective than the standalone treatments, meriting further clinical attention.

Microplasma radio frequency technology using stationary tips on pig skin: A histological study.

To investigate the histological properties of microplasma radiofrequency (MPRF) using a stationary tip in different treatment strategies on porcine skin. Two Bama miniature pigs received MPRF treatment with two types of stationary tips in eight groups of parameters (power, duration, and pass) on dorsal skin. Skin samples were collected from each treatment zone immediately, at 1 week and 1, 3, and 6 months after treatment. Hematoxylin and eosin (HE) and Masson staining were performed to assess histologic changes as well as neocollagenesis. The dynamic changes of heat shock protein 47 (HSP47) and heat shock protein 72 (HSP72) were also detected by immunohistochemistry. Skin damage increased with pulse energy, duration, and pass. Longer durations or repeated treatments may cause particularly severe skin damage. During the wound healing process, the newborn collagen of the dermis is rearranged. The distribution of HSP47 and HSP72 was consistent with the extent of collagen remodeling. It peaked 1 month after treatment. MPRF can effectively cause epidermal ablation, dermal collagen hyperplasia, and remodeling. Increasing power should be the first choice when increasing treatment intensity. For longer durations or repeated treatments, caution should be taken to avoid excessive skin trauma.

Micro-plasma radiofrequency and silicone gel dressings for treating early post-traumatic facial scars: A retrospective study

Although different options are available for treating post-traumatic facial scars, they remain a therapeutic challenge. To evaluate the safety and effectiveness of combined therapy using micro-plasma radiofrequency (MPRF) technology and silicone gel (SG) dressings for treating post-traumatic facial scars. This retrospective study was conducted at a single center. Patients with facial injuries in the outpatient and emergency units of the Department of Plastic Surgery at our hospital underwent debridement and cosmetic sutures performed by the same surgeon from October 2020 to October 2021. In the first arm, patients with facial injuries were treated with MPRF technology and SG, and in the second arm, they were treated with SG dressings alone. We observed the safety and effectiveness of these treatments in both arms. A total of 32 patients with facial injuries were treated with MPRF technology and SG dressings (combined treatment group), and 28 patients were treated with SG dressings alone (SG group). After 6 months of treatment, the Vancouver Scar Scale scores of the combined treatment and SG groups were 1.38±0.71 and 4.39±0.50, respectively, and the difference was statistically significant (P<0.01). After 6 months of treatment, the effectiveness rate in the combined treatment group was 93.8%, which was significantly higher than that in the SG group (67.9%), and the difference between the two groups was statistically significant (P<0.05). No obvious adverse reactions occurred in the two arms. Treating early post-traumatic facial scars with combined MPRF technology and SG is significantly better than treating them with SG alone; moreover, the combined therapy is safe and effective.

"Clinical Observation of Microplasma Radiofrequency Technology Combined With Glucocorticoid Injection in the Treatment of Hundreds of Cases of Hypertrophic Scar After Early Deep Burn and Scald".

To investigate the clinical efficacy and safety of microplasma radiofrequency technology combined with glucocorticoid injection in the treatment of hypertrophic scarring after early deep burns and scalding. A total of 150 patients with hypertrophic scars after early deep burns from June 2018 to June 2021 were randomly divided into 3 groups, with 50 cases in each group. The patients were treated with compound betamethasone injection (Group A), microplasma radiofrequency technique (Group B), and compound betamethasone injection combined with microplasma radiofrequency technology (Group C). Each course of treatment included 5 standard treatments, and they were performed 6 weeks apart. Each patient was analyzed using the Vancouver scar scale and visual analogy scale after each treatment. The results were compared over time and across groups using repeated measurement analysis of variance. A total of 138 patients in these 3 groups completed this study. As treatment continued, the Vancouver scar scale value of Group C decreased more rapidly than that of Group A and Group B, and the difference was statistically significant (P<0.05). In the improvement of scar pain and itching, there was little difference between Group C and Group A (P>0.05), but both were better than Group B, and the difference was statistically significant (P<0.05). Regarding the incidence of adverse reactions, there was little difference between Group C and Group B (P>0.05), but the incidence of adverse reactions was lower than that of Group A, and the difference was statistically significant (P<0.05). Microplasma radiofrequency combined with glucocorticoid injection in the treatment of hypertrophic scarring after early deep burns is effective, safe, and has a low incidence of adverse reactions, and it merits clinical promotion.

Treatment of nasal depressed scars using micro-plasma radiofrequency technology combined with subcision.

The nose is located in the middle of the face; therefore, nasal scarring will bring a significant psychological impact on patients. Although there are many treatment methods for depressed scars, these methods have varying degrees of efficacy and all carry certain adverse effects. A better treatment method is urgent to be found. In this study, the effect of micro-plasma radiofrequency technology combined with subcision to treat nasal depressed scars is evaluated. 18 Chinese patients with nasal depressed scars participated in this study. All patients received one session of micro-plasma radiofrequency treatment first. 2months later, subcision combined with micro-plasma radiofrequency technology was performed on them at 6-month intervals, and a total of 2sessions of combined treatment were performed. Goodman and Baron Scale was used to evaluate nasal scars before treatment and 6months after the final session. All 18 patients in this study had Grade 4 nasal scars before treatment. 6months after the end of treatment, 13 patients (72.2%) showed excellent or near total improvement, and 5 patients (27.8%) showed marked improvement. No adverse side effects were observed during treatment. Patient self-evaluation indicated that all patients were satisfied with the cosmetic outcomes. In this study, we explored a new treatment method for nasal depressed scars. We used micro-plasma radiofrequency technology combined with subcision to treat nasal depressed scars and obtained relatively satisfactory results with no adverse effects.

Laser and related photoelectric therapies for scar worth expecting

Effects of non-operative therapies for scar are very limited, and operative treatments are also often difficult to get satisfactory results. Safe, effective, simple, and feasible therapy for scar is urgently needed in clinic. Laser has been used for scar treatment for more than 30 years. There are many kinds of lasers, many of which have been reported to be used for scar treatment. Laser and related photoelectric therapies for scar have experienced long period of exploration, from the initial laser of continuous wavelength to the later pulsed laser, from ordinary spot laser in the early period to the present fractional laser. And there are intense pulsed light closely related to laser and non-light energy of micro-plasma radio-frequency technology. In recent years, with in-depth research of related theories, progress of technology and equipment, as well as accumulation of clinical experience, a great progress has been made in laser treatment for scar. In this article, related theories of photothermal interaction on skin tissue of laser, the present lasers and related photoelectric therapies often used for scar are introduced, and the existing problems and further development directions are also discussed.

CORRECTION OF VARIOUS TYPES OF FACIAL HYPERPIGMENTATION USING MICROPLASMA RADIO FREQUENCY TECHNOLOGY

Correction of facial hyperpigmentation is a very common and complex problem faced by dermatologists, cosmetologists and plastic surgeons. Recently developed microplasma radiofrequency technology allows to accurately and rapidly affect the areas with hyperpigmentation and is an effective method of its treatment. The aim of this study is to evaluate the effectiveness of hyperpigmentation treatment using microplasma radiofrequency technology. The study included 35 patients with benign hyperpigmentation with localization on the face. All patients had II - IV skin phototypes according to Fitzpatrick. We used a device with an output power of 60-90 W and performed 2-6 passes (rolling with a roller nozzle) in different directions. Three to five procedures were performed with 8-week intervals. As a result of treatment, all patients had improvement, which is manifested in clarification of hyperpigmentation spots of varying severity. Complications were not observed. Improvement of skin condition with reduction of hyperpigmentation phenomena was assessed by patients and physicians who compared digital images taken before the treatment and 2 months after the last procedure. The results of the study showed that the patients had a positive effect on the treatment of hyperpigmentation using microplasma radio frequency technology. The average index of pain intensity was estimated from 0 to 10 using a visual analog scale, which was 6.7 ± 0.7. After a course of therapy in 32 of 35 patients hyperpigmentation decreased by more than 51%, and 3 patients managed to achieve a clinical cure. The average improvement in the treatment of hyperpigmentation was 4.28. Thus, microplasma radiofrequency technology is a highly effective and safe method of treating facial hyperpigmentation.

Clinical efficacy of micro-plasma radiofrequency combined with local electron-beam radiation therapy in treatment of keloids

Objective To study the clinical efficacy of micro-plasma radiofrequency with joint electron-beam radiation treatment for keloids. Methods A total of 15 patients with keloids over half a year were treated with single time micro-plasma radiofrequency technology by roller tip at 80-100 watts. The hypofractionated electron-beam was used, with 9 Gy dose per time covering the scar with a 1 cm margin, within 24 hours and 1 week after the micro-plasma treatment. The Vancouver Scar Scales (VSS) were assessed before and 6 months after the treatment. Patients＇ satisfaction and the adverse reactions were evaluated 6 months after the treatment. Results There was astatistically significant difference between the mean VSS of 15 patients pre- and 6 months posttreatment (from 11.73±1.12 to 3.87±2.53, P<0.05). The degree of improvement was: excellent in 1 case, good 10 cases, fair 3 cases, and poor 1 case. Patients＇ assessment was: extremely satisfied in 6 cases, satisfied 6 cases, approximately satisfied 2 cases and dissatisfied 1 case. The adverse reactions included hyperpigmentation within the radiation field on the anterior chest wall in 1 case and delayed healing of 1 patient＇s scar wound. Conclusions Micro-plasma radiofrequency combined with electron-beam radiation therapy is highly effective and safe on keloids with good clinical application value. Key words: Keloid; Micro-plasma; Radio frequency; Radiotherapy; Electron beam

Microplasma radiofrequency technology combined with triamcinolone improved the therapeutic effect on Chinese patients with hypertrophic scar and reduced the risk of tissue atrophy.

ObjectiveThe current study aimed to assess the value of microplasma radiofrequency technology combined with triamcinolone for the therapy of Chinese patients with hypertrophic scar.MethodsA total of 120 participants with hypertrophic scars were enrolled in the current study. Participants were divided into two groups based on sex, and then randomly and evenly divided into four groups (Groups A, B, C, and D). Participants in Group A received microplasma radiofrequency technology combined with triamcinolone. Participants in Group B received microplasma radiofrequency technology combined with normal saline. Participants in Groups C and D received triamcinolone (40 and 10 mg/mL) injected directly into scar. Experienced physicians evaluated the condition of scars according to the Vancouver Scar Scale 1 month before and after the therapy.ResultsThere was no difference in age, sex, area, height and location of scars, and Vancouver Scar Scale scores before the therapy between any groups (P>0.05 for all). Vancouver Scar Scale scores after the therapy were significantly lower than those before the therapy in all groups (P<0.05 for all). Vancouver Scar Scale scores after the therapy in Group A were significantly lower than those after the therapy in Groups B and C (P<0.05 for all). Vancouver Scar Scale scores after the therapy in Group B were significantly higher than those after the therapy in Group C (P<0.05 for all) and similar to those after the therapy in Group D (P>0.05 for all). Incidences of tissue atrophy after the therapy were significantly lower in Groups A and B than in Group C (P<0.05 for all) and similar among Groups A, B, and D (P>0.05 for all).ConclusionMicroplasma radiofrequency technology combined with triamcinolone improved the therapeutic effect on Chinese patients with hypertrophic scar and reduced the risk of tissue atrophy compared with the use of either microplasma radiofrequency technology or triamcinolone injection alone.

Clinical effectiveness of micro-plasma combined with radio frequency in treatment of stretch marks

Objective To study the clinical effect and application value of micro-plasma beam joint radiofrequency treatment for the striae of pregnancy. Methods 21 female patients with the striae of pregnancy were included in this study, treated from the July 2012 to March 2014, aged 25-37 years; and time of the striae was from 3 months to 7 years. Micro-plasma radiofrequency technology was used to treat the striae, with interval of 30 days each time for total seven months. The total effective rate, satisfaction, and the adverse reaction were evaluated after the treatment. Results 21 patients included grade 4 in 6 cases, grade 6 in 10 cases, grade 2 in 4 cases and grade 1 in 1 case; the total effective rate was 95.2% (20/21). Satisfactory degree was for the level C in 6 cases, B in 14 cases, and A in 1 case, with total satisfactory rate of 95.2% (20/21). Adverse reactions included mild pigmentation in 2 patients after scab skin falling off, and disappeared at the end of the treatment course. Conclusions Micro-plasma beam combined with radio frequency in treating the striae of pregnancy has clear curative effect and good clinical application value. Key words: Micro-plasma; Stretch marks; Radio frequency

Commentary on “Comparison of a Fractional Microplasma Radiofrequency Technology and Carbon Dioxide Fractional Laser for the Treatment of Atrophic Acne Scars: A Randomized Split-Face Clinical Study”

I read with interest the article by Zhang and colleagues. The treatment of postacne scars is difficult, as many of us have said over the years. I think we were feeling sorry for ourselves over our inability to have a substantial effect on this seemingly insurmountable problem. We still are unable to reverse scars; we can only make them look less noticeable, maybe not as deep or less colored or more easily covered with make-up.

Comparison of a fractional micro-plasma radio-frequency technology versus fractional ultrapulsed CO2 laser for the treatment of atrophic acne scars

Objective To compare the efficacy of and adverse reactions to a fractional micro-plasma radio-frequency technology versus fractional ultrapulsed CO2 laser in the treatment of atrophic acne scars.Methods Twenty-one patients with atrophic acne scars were enrolled in this study.Half of each subject's face was treated with micro-plasma,and the other half with fractional ultrapulsed CO2 laser,for one session.Treatments were randomly administered in a split-face manner.The efficacy and adverse effects were evaluated 6 months after the treatment by using the following outcome parameters:ECCA grading scale (echelle d' evaluation clinique des cicatrices d'acne),degrees of post-treatment pain and edema,time taken for crusting and durations of inflammatory erythema,patients' subjective rating of improvement in scar by using a quartile grading scale.A non-parametric rank test was conducted to compare the efficacy and adverse effects between the two treatments.A scar model was established on both ears of a New Zealand big ear rabbit,and treated with the CO2 laser and micro-plasma respectively,immediately followed by the resection of scar tissue for the observation of histological changes.Results A decrease of ECCAscore was observed in 90.5％ (19/21) of the patients after micro-plasma treatment,and in 86.7％ (18/21) after CO2 laser treatment; no significant difference was observed in the response rate (P ＞ 0.05).In detail,ECCA score decreased by 31.5％ (from 50.71 to 34.76 ) after micro-plasma treatment,compared to 29.9％ (from 53.57 to 38.10) after CO2 laser treatmet.Mild edema was observed after micro-plasma treatment,with the duration of erythema and crusting being 13.95 days and 6.95 days,respectively,compared to 45.81 days and 10.10 days respectively,after CO2 laser treatment.Pigmentation occurred in none of the patients after micro-plasma treatment,but in 19％ after CO2 laser treatment.Animal experiment showed that microscopic ablation zones were broad and shallow after micro-plasma treatment,but narrow and deep after CO2 laser treatment.Conclusions Fractional micro-plasma and CO2 laser are both effective for the treatment of atrophic acne scars,but the former seems to have less side effects with a lower incidence of pigmentation. Key words: Cicatrix; Micro-plasma; Fractional laser

A novel fractional micro-plasma radio-frequency technology for the treatment of facial scars and rhytids: A pilot study

Introduction: Fractional ablative and non-ablative lasers have gained popularity in the treatment of acne scars and rhytids due to their efficacy and improved tolerability. Plasma and radio frequency (RF) have also emerged as methods for ablative or non-ablative energy delivery. We report preliminary experience with a novel fractional micro-plasma RF device for the treatment of facial acne scars and rhytids. Methods: Sixteen patients with facial acne scars or rhytids were treated at 4-week intervals. Treatment parameters were titrated to an immediate end point of moderate erythema. The clinical end point for cessation of treatment was the attainment of satisfactory clinical results. Results were monitored photographically up to 3 months after treatment. Results: Acne scars showed marked improvement after two to four treatments. Facial rhytids demonstrated reduced depth after two treatments and marked improvement after four treatments. Treatment was well tolerated by all participants, with transient erythema and short downtime. These results provide initial evidence for the safety and effectiveness of fractional micro-plasma RF as a low-downtime and well-tolerated modality for the treatment of acne scars and facial rhytids.