Understanding phenomena associated with the multiple effects/interactions of the fusion nuclear environment on liquid metal flow is required to correctly design liquid metal (LM) blankets for fusion facilities. These effects are investigated in the present work by numerically simulating 3D LM MHD flow. The simulated geometry consists of a straight, vertical duct which runs perpendicular to a strong, fringing applied magnetic field. There is also a region of applied heating as the primary goal is to explore buoyancy effects in MHD duct flows. Results are presented for both buoyancy assisted (upwards) and buoyancy opposed (downwards) flows in conducting and insulating ducts for a range of Hartmann numbers (Ha) up to 100, Reynolds numbers (Re) from 103 to 104 and Grashof (Gr) numbers from 107 to 108. While increasing Gr or decreasing Re increases buoyancy effects, increasing Ha was shown to increase maximum temperature through turbulence reduction. The extent to which the MHD mixed convection flows are quasi-2D is analyzed and buoyant effects, in competition with electromagnetic forces, are shown to bring about 3D flow features not seen in purely MHD flows. Volumetric nuclear heating with steep gradients is applied to the vertical MHD flows for comparison to flows with surface heating only. Surface heating generates stronger buoyancy effects than volumetric heating of the same total power; however, many of the same phenomena occur. Therefore, surface heating, the only option for lab experiments, can provide indication of the effects of volumetric heating in MHD flows.