For someone interested in studying the cultures and literatures of Mexico's northern border or those of the US Southwest, it is important to take into account that when trying to investigate the subjects or objects of study – human, textual, or visual – one cannot put aside the ever-present tension between national and regional discourses, nor overlook symbolic representations of those discourses. Consequently, this article proposes to sketch and reflect about some identities of Mexico's northern border that have been articulated from different perspectives and inscribed in literary texts and national and international cinemas. It will also reflect on cultural production from and about Ciudad Juárez at the turn of the 21st century and how that cultural production dialogues with different symbolic representations.