Quantification Metrics Research Articles

High-Resolution Snow-Covered Area Mapping in Forested Mountain Ecosystems Using PlanetScope Imagery

Improving high-resolution (meter-scale) mapping of snow-covered areas in complex and forested terrains is critical to understanding the responses of species and water systems to climate change. Commercial high-resolution imagery from Planet Labs, Inc. (Planet, San Francisco, CA, USA) can be used in environmental science, as it has both high spatial (0.7–3.0 m) and temporal (1–2 day) resolution. Deriving snow-covered areas from Planet imagery using traditional radiometric techniques have limitations due to the lack of a shortwave infrared band that is needed to fully exploit the difference in reflectance to discriminate between snow and clouds. However, recent work demonstrated that snow cover area (SCA) can be successfully mapped using only the PlanetScope 4-band (Red, Green, Blue and NIR) reflectance products and a machine learning (ML) approach based on convolutional neural networks (CNN). To evaluate how additional features improve the existing model performance, we: (1) build on previous work to augment a CNN model with additional input data including vegetation metrics (Normalized Difference Vegetation Index) and DEM-derived metrics (elevation, slope and aspect) to improve SCA mapping in forested and open terrain, (2) evaluate the model performance at two geographically diverse sites (Gunnison, Colorado, USA and Engadin, Switzerland), and (3) evaluate the model performance over different land-cover types. The best augmented model used the Normalized Difference Vegetation Index (NDVI) along with visible (red, green, and blue) and NIR bands, with an F-score of 0.89 (Gunnison) and 0.93 (Engadin) and was found to be 4% and 2% better than when using canopy height- and terrain-derived measures at Gunnison, respectively. The NDVI-based model improves not only upon the original band-only model’s ability to detect snow in forests, but also across other various land-cover types (gaps and canopy edges). We examined the model’s performance in forested areas using three forest canopy quantification metrics and found that augmented models can better identify snow in canopy edges and open areas but still underpredict snow cover under forest canopies. While the new features improve model performance over band-only options, the models still have challenges identifying the snow under trees in dense forests, with performance varying as a function of the geographic area. The improved high-resolution snow maps in forested environments can support studies involving climate change effects on mountain ecosystems and evaluations of hydrological impacts in snow-dominated river basins.

Reference-free learning-based similarity metric for motion compensation in cone-beam CT

Purpose. Patient motion artifacts present a prevalent challenge to image quality in interventional cone-beam CT (CBCT). We propose a novel reference-free similarity metric (DL-VIF) that leverages the capability of deep convolutional neural networks (CNN) to learn features associated with motion artifacts within realistic anatomical features. DL-VIF aims to address shortcomings of conventional metrics of motion-induced image quality degradation that favor characteristics associated with motion-free images, such as sharpness or piecewise constancy, but lack any awareness of the underlying anatomy, potentially promoting images depicting unrealistic image content. DL-VIF was integrated in an autofocus motion compensation framework to test its performance for motion estimation in interventional CBCT. Methods. DL-VIF is a reference-free surrogate for the previously reported visual image fidelity (VIF) metric, computed against a motion-free reference, generated using a CNN trained using simulated motion-corrupted and motion-free CBCT data. Relatively shallow (2-ResBlock) and deep (3-Resblock) CNN architectures were trained and tested to assess sensitivity to motion artifacts and generalizability to unseen anatomy and motion patterns. DL-VIF was integrated into an autofocus framework for rigid motion compensation in head/brain CBCT and assessed in simulation and cadaver studies in comparison to a conventional gradient entropy metric. Results. The 2-ResBlock architecture better reflected motion severity and extrapolated to unseen data, whereas 3-ResBlock was found more susceptible to overfitting, limiting its generalizability to unseen scenarios. DL-VIF outperformed gradient entropy in simulation studies yielding average multi-resolution structural similarity index (SSIM) improvement over uncompensated image of 0.068 and 0.034, respectively, referenced to motion-free images. DL-VIF was also more robust in motion compensation, evidenced by reduced variance in SSIM for various motion patterns (σ DL-VIF = 0.008 versus σ gradient entropy = 0.019). Similarly, in cadaver studies, DL-VIF demonstrated superior motion compensation compared to gradient entropy (an average SSIM improvement of 0.043 (5%) versus little improvement and even degradation in SSIM, respectively) and visually improved image quality even in severely motion-corrupted images.Conclusion: The studies demonstrated the feasibility of building reference-free similarity metrics for quantification of motion-induced image quality degradation and distortion of anatomical structures in CBCT. DL-VIF provides a reliable surrogate for motion severity, penalizes unrealistic distortions, and presents a valuable new objective function for autofocus motion compensation in CBCT.

Gadolinium-based contrast agent attenuation does not impact PET quantification in simultaneous dynamic contrast enhanced breast PET/MR.

Simultaneous PET/MR imaging involves injection of a radiopharmaceutical and often also includes administration of a gadolinium-based contrast agent (GBCA). Phantom model studies indicate that attenuation of annihilation photons by GBCAs does not bias quantification metrics of PET radiopharmaceutical uptake. However, a direct comparison of attenuation-corrected PET values before and after administration of GBCA has not been performed in patients imaged with simultaneous dynamic PET/MR. The purpose of this study was to investigate the attenuating effect of GBCAs on standardized uptake value (SUV) quantification of 18 F-fluorodeoxyglucose (FDG) uptake in invasive breast cancer and normal tissues using simultaneous PET/MR. The study included 13 women with newly diagnosed invasive breast cancer imaged using simultaneous dedicated prone breast PET/MR with FDG. PET data collection and two-point Dixon-based MR attenuation correction sequences began simultaneously before the administration of GBCA to avoid a potential impact of GBCA on the attenuation correction map. A standard clinical dose of GBCA was intravenously administered for the dynamic contrast enhanced MR sequences obtained during the simultaneous PET data acquisition. PET data were dynamically reconstructed into 60 frames of 30 s each. Three timing windows were chosen consisting of a single frame (30 s), two frames (60 s), or four frames (120 s) immediately before and after contrast administration. SUVmax and SUVmean of the biopsy-proven breast malignancy, fibroglandular tissue of the contralateral normal breast, descending aorta, and liver were calculated prior to and following GBCA administration. Percent change in the SUV metrics were calculated to test for a statistically significant, non-zero percent change using Wilcoxon signed-rank tests. No statistical change in SUVmax or SUVmean was found for the breast malignancies or normal anatomical regions during the timing windows before and after GBCA administration. GBCAs do not significantly impact the results of PET quantification by means of additional attenuation. However, GBCAs may still affect quantification by affecting MR acquisitions used for MR-based attenuation correction which this study did not address. Corrections to account for attenuation due to clinical concentrations of GBCAs are not necessary in simultaneous PET/MR examinations when MR-based attenuation correction sequences are performed prior to GBCA administration.

Resilience Metrics for Integrated Power and Natural Gas Systems

The integrated power and natural gas system (IPGS) is a promising technique against extreme weather. In this letter, a valley-shaped resilience model is proposed to evaluate the performance of IPGSs under extreme weather and inter-energy assistances between the electric power sector and the natural gas sector. Furthermore, a quantification metrics framework for IPGS resilience evaluation is raised. Novel metrics are proposed, especially the distortion rate (<inline-formula> <tex-math notation="LaTeX">$\varTheta $ </tex-math></inline-formula>) and linepack effect (<inline-formula> <tex-math notation="LaTeX">$\varDelta t^{*}$ </tex-math></inline-formula>) for quantifying coupling tightness and assistance from natural gas transient in resilience perspective respectively. Evaluation on different restoration strategies is conducted to validate the effectiveness of the proposed metrics framework.

Quantification of operational flexibility from a portfolio of flexible energy resources

Flexibility will be required as more renewable generation is integrated in the power system. Therefore, entities such as Flexibility Service Providers (FSPs) have emerged who can control a diverse set of resources in their portfolio to provide requested flexibility. An accurate and reliable assessment of the amount of dispatchable flexibility in FSP’s portfolio considering demand response activation, ramp rate, and post-activation rebound effects, etc. is important. In case FSP portfolio cannot fulfill the flexibility request, it must be known beforehand to avoid imbalance penalties. In this paper, we propose three flexibility quantification metrics: Expected Unserved Flexible Energy (EUFE), Expected Duration of Insufficient Flexibility (EDIF), and Expected Flexibility Index (EFI). These metrics are calculated using scenario-based simulations. The three metrics provide the FSP with quantifiable as well as graphical information on the magnitude and the duration of insufficient flexibility well ahead of gate closure time. This helps the FSP to design appropriate demand response programs (DRPs) and formulate their operational policy. These metrics account for uncertainty in forecasts of flexibility requests by evaluating multiple scenarios by conducting an operational simulation. With a representative case study, it is shown how an FSP can use the metrics to design DRPs, and when needed, schedule intraday market participation.

Metrics for Quantification of By-Process Segregation in Ge-Rich GST

Ge-rich GST alloys are the most promising materials for phase-change memory (PCM) to fulfill the soldering compliance and the tough data retention requirements of automotive applications. Significant efforts have been made to engineer those materials and optimize their integration inside the fabrication process of PCM. In this perspective, the physical characterization of the device and the material is instrumental in understanding the underlying physics, improving the process, and optimizing the interactions between the device, the process, and the material itself. Especially, microscopic investigations have gathered increasing interest, giving detailed descriptions of local material modulations that have a crucial role in cell programming and reliability performances. In this work, a deep analysis of Ge-rich GST microscopic alloy evolution during the integration process has been performed, exploiting analysis by EELS with TEM supported by a novel statistical data post-processing method. The new proposed statistical-based methodology also introduces new simple metrics for elemental compositional evaluations that have been exploited for process engineering.

Unsupervised arterial spin labeling image superresolution via multiscale generative adversarial network.

Arterial spin labeling (ASL) magnetic resonance imaging (MRI) is an advanced noninvasive imaging technology that can measure cerebral blood flow (CBF) quantitatively without a contrast agent injection or radiation exposure. However, because of the weak labeling, conventional ASL images usually suffer from low signal-to-noise ratio (SNR), poor spatial resolution, and long acquisition time. Therefore, a method that can simultaneously improve the spatial resolution and SNR isneeded. In this work, we proposed an unsupervised superresolution (SR) method to improve ASL image resolution based on a pyramid of generative adversarial networks (GAN). Through layer-by-layer training, the generators can learn features from the coarsest to the finest. The last layer's generator that contains fine details and textures was used to generate the final SR ASL images. In our proposed framework, the corresponding T1-weighted MR image was supplied as a second-channel input of the generators to provide high-resolution prior information. In addition, a low-pass-filter loss term was included to suppress the noise of the original ASL images. To evaluate the performance of the proposed framework, a simulation study and two real-patient experiments based on the in vivo datasets obtained from three healthy subjects on a 3T MR scanner were conducted, regarding the low-resolution (LR) to normal-resolution (NR) and the NR-to-SR tasks. The proposed method was compared to the nearest neighbor interpolation, trilinear interpolation, third-order B-splines interpolation methods, and deep image prior (DIP) with the peak signal-to-noise ratio (PSNR) and structural similarity index (SSIM) as the quantification metrics. The averaged ASL images acquired with 44 min acquisition time were used as the ground truth for real-patient LR-to-NR study. The ablation studies of low-pass-filter loss term and T1-weighted MR image were performed based on simulation data. For the simulation study, results show that the proposed method achieved significantly higher PSNR ( -value 0.05) and SSIM ( -value 0.05) than the nearest neighbor interpolation, trilinear interpolation, third-order B-splines interpolation, and DIP methods. For the real-patient LR-to-NR experiment, results show that the proposed method can generate high-quality SR ASL images with clearer structure boundaries and low noise levels and has the highest mean PSNR and SSIM. For real-patient NR-to-SR tasks, the structure of the results using the proposed method is sharper and clearer, which are the most similar to the structure of the reference 44 min acquisition image than other methods. The proposed method also shows the ability to remove artifacts in the NR image while superresolution. The ablation study verified that the low-pass-filter loss term and T1-weighted MR image are necessary for the proposedmethod. The proposed unsupervised multiscale GAN framework can simultaneously improve spatial resolution and reduce image noise. Experiment results from simulation data and three healthy subjects show that the proposed method achieves better performance than the nearest neighbor interpolation, the trilinear interpolation, the third-order B-splines interpolation, and DIP methods.

Comparing metrics for quantification of children’s tongue shape complexity using ultrasound imaging

ABSTRACT Speech sound disorders can pose a challenge to communication in children that may persist into adulthood. As some speech sounds are known to require differential control of anterior versus posterior regions of the tongue body, valid measurement of the degree of differentiation of a given tongue shape has the potential to shed light on development of motor skill in typical and disordered speakers. The current study sought to compare the success of multiple techniques in quantifying tongue shape complexity as an index of degree of lingual differentiation in child and adult speakers. Using a pre-existing data set of ultrasound images of tongue shapes from adult speakers producing a variety of phonemes, we compared the extent to which three metrics of tongue shape complexity differed across phonemes/phoneme classes that were expected to differ in articulatory complexity. We then repeated this process with ultrasound tongue shapes produced by a sample of young children. The results of these comparisons suggested that a modified curvature index and a metric representing the number of inflection points best reflected small changes in tongue shapes across individuals differing in vocal tract size. Ultimately, these metrics have the potential to reveal delays in motor skill in young children, which could inform assessment procedures and treatment decisions for children with speech delays and disorders.

Open access, responsibility and the “platformization” of academic publishing

Digitalization was supposed to be a transformation force for the academic publishing sector, but it has reinforced the oligopoly of for-profit academic publishers. Open access (OA) was also meant to counterbalance this situation, but after a decade of efforts it seems that it has not achieved their goals. This essay explores how the combination of digitalization and OA have contributed to reinforce the lock-in effects exerted in the sector by digital platforms operated by for-profit academic publishers. I also explore alternative paths for the development of OA with the theoretical lenses that provide responsible innovation, putting social emphasis at the politics and values that lie at the heart of academia. I argue that exploitation, appropriation of labor and quantification metrics widely present in this social domain must be counterbalanced with different actions that do not focus alone in making freely available scientific articles for citizens.

Enriching stochastic model updating metrics: An efficient Bayesian approach using Bray-Curtis distance and an adaptive binning algorithm

In practical engineering, experimental data is not fully in line with the true system response due to various uncertain factors, e.g., parameter imprecision, model uncertainty, and measurement errors. In the presence of mixed sources of aleatory and epistemic uncertainty, stochastic model updating is a powerful tool for model validation and parameter calibration. This paper investigates the use of Bray-Curtis (B-C) distance in stochastic model updating and proposes a Bayesian approach addressing a scenario where the dataset contains multiple outliers. In the proposed method, a B-C distance-based uncertainty quantification metric is employed, that rewards models for which the discrepancy between observations and simulated samples is small while penalizing those which exhibit large differences. To improve the computational efficiency, an adaptive binning algorithm is developed and embedded into the Bayesian approximate computation framework. The merit of this algorithm is that the number of bins is automatically selected according to the difference between the experimental data and the simulated data. The effectiveness and efficiency of the proposed method is verified via two numerical cases and an engineering case from the NASA 2020 UQ challenge. Both static and dynamic cases with explicit and implicit propagation models are considered.

Tangle: A metric for quantifying complexity and erratic behavior in short time series.

Temporal complexity refers to qualities of a time series that are emergent, erratic, or not easily described by linear processes. Quantifying temporal complexity within a system is key to understanding the time based dynamics of said system. However, many current methods of complexity quantification are not widely used in psychological research because of their technical difficulty, computational intensity, or large number of required data samples. These requirements impede the study of complexity in many areas of psychological science. A method is presented, tangle, which overcomes these difficulties and allows for complexity quantification in relatively short time series, such as those typically obtained from psychological studies. Tangle is a measure of how dissimilar a given process is from simple periodic motion. Tangle relies on the use of a three-dimensional time delay embedding of a one-dimensional time series. This embedding is then iteratively scaled and premultiplied by a modified upshift matrix until a convergence criterion is reached. The efficacy of tangle is shown on five mathematical time series and using emotional stability, anxiety time series data obtained from 65 socially anxious participants over a 5-week period, and positive affect time series derived from a single participant who experienced a major depression episode during measurement. Simulation results show tangle is able to distinguish between different complex temporal systems in time series with as few as 50 samples. Tangle shows promise as a reliable quantification of irregular behavior of a time series. Unlike many other complexity quantification metrics, tangle is technically simple to implement and is able to uncover meaningful information about time series derived from psychological research studies. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Assessment of different quantification metrics of [18F]-NaF PET/CT images of patients with abdominal aortic aneurysm

BackgroundWe aim to assess the spill-in effect and the benefit in quantitative accuracy for [18F]-NaF PET/CT imaging of abdominal aortic aneurysms (AAA) using the background correction (BC) technique. MethodsSeventy-two datasets of patients diagnosed with AAA were reconstructed with ordered subset expectation maximization algorithm incorporating point spread function (PSF). Spill-in effect was investigated for the entire aneurysm (AAA), and part of the aneurysm excluding the region close to the bone (AAAexc). Quantifications of PSF and PSF+BC images using different thresholds (% of max. SUV in target regions-of-interest) to derive target-to-background (TBR) values (TBRmax, TBR90, TBR70 and TBR50) were compared at 3 and 10 iterations. ResultsTBR differences were observed between AAA and AAAexc due to spill-in effect from the bone into the aneurysm. TBRmax showed the highest sensitivity to the spill-in effect while TBR50 showed the least. The spill-in effect was reduced at 10 iterations compared to 3 iterations, but at the expense of reduced contrast-to-noise ratio (CNR). TBR50 yielded the best trade-off between increased CNR and reduced spill-in effect. PSF+BC method reduced TBR sensitivity to spill-in effect, especially at 3 iterations, compared to PSF (P-value ≤ 0.05). ConclusionTBR50 is robust metric for reduced spill-in and increased CNR.

Qualitative Evaluation of Common Quantitative Metrics for Clinical Acceptance of Automatic Segmentation: a Case Study on Heart Contouring from CT Images by Deep Learning Algorithms

Organs-at-risk contouring is time consuming and labour intensive. Automation by deep learning algorithms would decrease the workload of radiotherapists and technicians considerably. However, the variety of metrics used for the evaluation of deep learning algorithms make the results of many papers difficult to interpret and compare. In this paper, a qualitative evaluation is done on five established metrics to assess whether their values correlate with clinical usability. A total of 377 CT volumes with heart delineations were randomly selected for training and evaluation. A deep learning algorithm was used to predict the contours of the heart. A total of 101 CT slices from the validation set with the predicted contours were shown to three experienced radiologists. They examined each slice independently whether they would accept or adjust the prediction and if there were (small) mistakes. For each slice, the scores of this qualitative evaluation were then compared with the Sørensen-Dice coefficient (DC), the Hausdorff distance (HD), pixel-wise accuracy, sensitivity and precision. The statistical analysis of the qualitative evaluation and metrics showed a significant correlation. Of the slices with a DC over 0.96 (N = 20) or a 95% HD under 5 voxels (N = 25), no slices were rejected by the readers. Contours with lower DC or higher HD were seen in both rejected and accepted contours. Qualitative evaluation shows that it is difficult to use common quantification metrics as indicator for use in clinic. We might need to change the reporting of quantitative metrics to better reflect clinical acceptance.

Validation Principles of Agricultural Machine Multibody Dynamics Models

HighlightsThis study focused on proper validation methodology for agricultural machine multibody dynamic models.Experimental design included categorizing subsystems, data acquisition, testing, and data pre-processing.Three error quantification metrics are proposed to summarize model performance and overall agreement.Abstract. Multibody dynamic (MBD) models are required to be accurate if they are to be used with confidence. To determine the overall accuracy of an agricultural machine MBD model, the model needs to be validated through proper experimental design principles and error analysis. At a high-level, the main methodology concepts for the experimental design involve categorizing dynamic subsystems, creating a data acquisition plan, determining and completing experimental testing, and pre-processing of physical and virtual time series datasets. This paper provides a methodology and example validation process for an MBD model of an agricultural self-propelled sprayer. As part of the experimental testing, a tip test revealed that the vertical center of gravity of the MBD model resulted in a 2.8% error from the physical machine. Furthermore, to summarize simulation model performance against physical data, three error quantification metrics for time-series data comparison are proposed: (1) correlation coefficient, (2) two-sample t-test and two-sample F-test, and (3) standard deviation of absolute error. For determining whether there is an acceptable level of agreement, this study proposes that the correlation coefficient should be greater than 0.7, the two-sample t-test and two-sample F-test should both pass (but with special consideration of the resulting confidence intervals if they fail), and that the standard deviation of absolute error should be less than 25% of the standard deviation of physical time series data. These error metrics, together with their defined sets of agreement criteria, resulted in detecting where the self-propelled sprayer system was experiencing validation issues and eventually the overall practical validation of the MBD model. Keywords: Agricultural machines, Confidence, Error metrics, Models, Multibody dynamics (MBD), Simulation, Validation.

Quantifying Uncertainties in Passive Microwave Remote Sensing of Soil Moisture via a Bayesian Probabilistic Inversion Method

Improving the accuracy of remotely sensed soil moisture (SM) is a challenging and popular topic. Quantifying the uncertainty in the SM inversion process and enhancing the confidence of SM retrieval are promising ways to address this challenge but have received little attention. We present a Bayesian probabilistic inversion algorithm that can simultaneously retrieve SM, surface roughness, and vegetation optical depth data and quantify the uncertainty in the inversion. The proposed algorithm is evaluated using airborne polarimetric L-band multibeam radiometer (PLMR) observations. We use three combinations, 3-angular observations at V-polarization (3CV), 3-angular observations at H-polarization (3CH) and 6-channel observations (6CA), to identify the optimal configuration for SM retrieval by taking advantage of the PLMR’s dual-polarization and multiple angles. Uncertainties are quantified by introducing multiple uncertainty quantification metrics into Bayesian posterior distributions of SM retrievals. The estimates are validated against multiscale ground-based measurements, including manual measurements and wireless sensor network (WSN) measurements, and the spatial representativeness of the ground-based reference regarding the validation of pixel-scale SM retrievals is discussed. The 6CA attempt yields the best SM estimates (correlation coefficient (R) ≥ 0.864, root mean square error (RMSE) ≤0.04 m3/m3, and unbiased RMSE (unRMSE) ≤ 0.035 m3/m3), while the 3CH attempt yields the lowest uncertainty. Additionally, dense manual measurements are more representative than sparsely distributed WSN measurements. Overall, combining dual-polarized observations yields the best SM estimates but introduces additional uncertainty. This study highlights uncertainties quantification in SM inversion and thus provides confidence in SM inversion, facilitating improved SM retrieval algorithms.

Probabilistic modelling of deception-based security framework using markov decision process

Existing studies using deception are ad-hoc attempts and few theoretical models have been designed to plan and integrate deception. We theorise that a pre-planning stage should be a fundamental part to obtain information about the attackers’ behaviours and the attack process by analysing known attacks. This will help plan and take defence actions by actively interacting with the attackers and predicting their actions using a probabilistic approach. This paper proposes a framework that provides a theoretical understanding to plan and integrate deception systematically and strategically. We also present probabilistic modelling to predict attack actions by formalising a real case of attacks captured on simulated Internet of Things devices as an Markov Decision Process (MDP) and verifying related properties using Probabilistic Symbolic Model Checker (PRISM). MDP’s properties verification results reveal that the associated cost for defence actions can be decreased by successfully predicting attackers’ probable actions. Moreover, we identify several quantification metrics (e.g. cost, reward, trust, incentive and penalty) to evaluate the performance of actions performed by attackers and defenders.

Standard SPECT myocardial perfusion estimation from half-time acquisitions using deep convolutional residual neural networks

IntroductionThe purpose of this work was to assess the feasibility of acquisition time reduction in MPI-SPECT imaging using deep leering techniques through two main approaches, namely reduction of the acquisition time per projection and reduction of the number of angular projections. MethodsSPECT imaging was performed using a fixed 90° angle dedicated dual-head cardiac SPECT camera. This study included a prospective cohort of 363 patients with various clinical indications (normal, ischemia, and infarct) referred for MPI-SPECT. For each patient, 32 projections for 20 seconds per projection were acquired using a step and shoot protocol from the right anterior oblique to the left posterior oblique view. SPECT projection data were reconstructed using the OSEM algorithm (6 iterations, 4 subsets, Butterworth post-reconstruction filter). For each patient, four different datasets were generated, namely full time (20 seconds) projections (FT), half-time (10 seconds) acquisition per projection (HT), 32 full projections (FP), and 16 half projections (HP). The image-to-image transformation via the residual network was implemented to predict FT from HT and predict FP from HP images in the projection domain. Qualitative and quantitative evaluations of the proposed framework was performed using a tenfold cross validation scheme using the root mean square error (RMSE), absolute relative error (ARE), structural similarity index, peak signal-to-noise ratio (PSNR) metrics, and clinical quantitative parameters. ResultsThe results demonstrated that the predicted FT had better image quality than the predicted FP images. Among the generated images, predicted FT images resulted in the lowest error metrics (RMSE = 6.8 ± 2.7, ARE = 3.1 ± 1.1%) and highest similarity index and signal-to-noise ratio (SSIM = 0.97 ± 1.1, PSNR = 36.0 ± 1.4). The highest error metrics (RMSE = 32.8 ± 12.8, ARE = 16.2 ± 4.9%) and the lowest similarity and signal-to-noise ratio (SSIM = 0.93 ± 2.6, PSNR = 31.7 ± 2.9) were observed for HT images. The RMSE decreased significantly (P value < .05) for predicted FT (8.0 ± 3.6) relative to predicted FP (6.8 ± 2.7). ConclusionReducing the acquisition time per projection significantly increased the error metrics. The deep neural network effectively recovers image quality and reduces bias in quantification metrics. Further research should be undertaken to explore the impact of time reduction in gated MPI-SPECT.

Automated quantification of COVID-19 pneumonia severity in chest CT using histogram-based multi-level thresholding segmentation

BackgroundChest computed tomography (CT) has proven its critical importance in detection, grading, and follow-up of lung affection in COVID-19 pneumonia. There is a close relationship between clinical severity and the extent of lung CT findings in this potentially fatal disease. The extent of lung lesions in CT is an important indicator of risk stratification in COVID-19 pneumonia patients. This study aims to explore automated histogram-based quantification of lung affection in COVID-19 pneumonia in volumetric computed tomography (CT) images in comparison to conventional semi-quantitative severity scoring. This retrospective study enrolled 153 patients with proven COVID-19 pneumonia. Based on the severity of clinical presentation, the patients were divided into three groups: mild, moderate and severe. Based upon the need for oxygenation support, two groups were identified as follows: common group that incorporated mild and moderate severity patients who did not need intubation, and severe illness group that included patients who were intubated. An automated multi-level thresholding histogram-based quantitative analysis technique was used for evaluation of lung affection in CT scans together with the conventional semi-quantitative severity scoring performed by two expert radiologists. The quantitative assessment included volumes, percentages and densities of ground-glass opacities (GGOs) and consolidation in both lungs. The results of the two evaluation methods were compared, and the quantification metrics were correlated.ResultsThe Spearman’s correlation coefficient between the semi-quantitative severity scoring and automated quantification methods was 0.934 (p < 0.0001).ConclusionsThe automated histogram-based quantification of COVID-19 pneumonia shows good correlation with conventional severity scoring. The quantitative imaging metrics show high correlation with the clinical severity of the disease.

Metrics for software requirements specification quality quantification

The initial and crucial phase of the automation and software development is identifying requirements and documenting them in an appropriate format that denotes software requirement specification (SRS). The quality and productivity at different phases of the software development depend on requirements specification. The quality of the end product of software development is proportionate to the quality of SRS. Hence, estimating the quality of the SRS is essential. Though the numerous metrics have been defined in contemporary research, the IEEE standard metrics are considered authentic to scale SRS quality. This manuscript endeavored to redefine the IEEE standard metrics’ measuring approaches to improvise SRS quality assessment. The experimental study exhibiting the significance and robustness of the proposed approach that compared to the contemporary contributions of the recent literature

Improved neuropathological identification of traumatic brain injury through quantitative neuroimaging and neural network analyses: Some practical approaches for the neurorehabilitation clinician.

Quantitative neuroimaging analyses have the potential to provide additional information about the neuropathology of traumatic brain injury (TBI) that more thoroughly informs the neurorehabilitation clinician. Quantitative neuroimaging is typically not covered in the standard radiological report, but often can be extracted via post-processing of clinical neuroimaging studies, provided that the proper volume acquisition sequences were originally obtained. Research and commercially available quantitative neuroimaging methods provide region of interest (ROI) quantification metrics, lesion burden volumetrics and cortical thickness measures, degree of focal encephalomalacia, white matter (WM) abnormalities and residual hemorrhagic pathology. If present, diffusion tensor imaging (DTI) provides a variety of techniques that aid in evaluating WM integrity. Using quantitatively identified structural and ROI neuropathological changes are most informative when done from a neural network approach. Viewing quantitatively identifiable damage from a neural network perspective provides the neurorehabilitation clinician with an additional tool for linking brain pathology to understand symptoms, problems and deficits as well as aid neuropsychological test interpretation. All of these analyses can be displayed in graphic form, including3-D image analysis. A case study approach is used to demonstrate the utility of quantitative neuroimaging and network analyses in TBI. Quantitative neuroimaging may provide additional useful information for the neurorehabilitation clinician.