Methodological Considerations Research Articles

Methodological considerations in calculating the minimal clinically important change score for the core outcome measures index (COMI): insights from a large single-centre spine surgery registry.

The Minimal Clinically Important Change (MCIC) is used in conjunction with Patient-Reported Outcome Measures (PROMs) to determine the clinical relevance of changes in health status. MCIC measures a change within the same person or group over time. This study aims to evaluate the variability in computing MCIC for the Core Outcome Measure Index (COMI) using different methods. Data from a spine centre in Switzerland were used to evaluate variations in MCIC for the COMI score. Distribution-based and anchor-based methods (predictive and nonpredictive) were applied. Bayesian bootstrap estimated confidence intervals. From 27,003 cases, 9821 met the inclusion criteria. Distribution-based methods yielded MCIC values from 0.4 to 1.4. Anchor-based methods showed more variability, with MCIC values from 1.5 to 4.9. Predictive anchor-based methods also provided variable MCIC values for improvement (0.3-2.4), with high sensitivity and specificity. MCIC calculation methods produce varying values, emphasizing careful method selection. Distribution-based methods likely measure minimal detectable change, while non-predictive anchor-based methods can yield high MCIC values due to group averaging. Predictive anchor-based methods offer more stable and clinically relevant MCIC values for improvement but are affected by prevalence and reliability corrections.

What do we know about femicide in Italy? Data and insights from a repeated cross-sectional study

Abstract Background Gender-based violence represents a huge public health issue, affecting mental, physical health and productivity. It is a significant obstacle to achieving gender equality and the empowerment of all women. While the overall homicide rate is decreasing in Italy, femicide, the intentional killing of women due to gender-related motivations, remains stable over time. This is the first study in Italy to evaluate potential risk factors of femicide, exploring the sociodemographic characteristics of victims and perpetrators of femicides, as well as the geographic distribution across Italy, with insights into differences between the size of municipalities and between geographic areas. Methods A repeated cross-sectional study was conducted to investigate femicides in Italy from 2020 to 2023 using data sources from Non Una Di Meno, an Italian NGO, and the Italian National Institute of Statistics. Results Our preliminary findings show that the majority (83%) of homicides of women were femicides. On a final sample of 403 femicides, in most cases (94,3%) the victims were more likely to be hit by their current or former partner or by a family member. In 97% of cases perpetrator was a man. In more than 50% of cases, both the victims and the perpetrators were under 55 years old (respectively, 51,8% and 57,9%). Femicide rates was 0.33 per 100,000 women. There appear to be no significant differences between the rates of femicide as the size of the municipality and the geographic macro-area vary, highlighting the extensive spread of the phenomenon throughout the territory. Conclusions Our findings show that femicide is a systematic and widespread phenomenon that occurs mostly within the home and needs interventions at the European level to prevent systemic violence against women. Moreover, this study provides methodological considerations to define femicide, suggests improvements to data collection methods and offer insights for future research in this field. Key messages • It is important to gather robust data on gender-based homicide, as it represents a public health issue. • Femicide is a pervasive and systematic phenomenon that predominantly occurs within the home and requires intervention at the European level.

Mapping Muslim Chaplaincy: An Analytic Review of Publications between 1989 and 2023

Abstract This article analyses the emergent field of Muslim chaplaincy research by reviewing English-language publications in this growing area of professional religious work, especially in Europe and the United States. After presenting the method of our enquiry, we provide a quantitative and qualitative analysis of the literature reviewed. We then focus on three key topics in Muslim Chaplaincy Studies that derive from our quantitative and qualitative research. These are: the training of Muslim chaplains, which is strongly linked to professionalisation, the vocabulary and sources that underpin Muslim chaplaincy and, finally, the significance of the increasing involvement of Muslim women in this area of professional religious work and leadership. Having identified exactly 100 publications related to the development of Muslim chaplaincy, many of them arising from empirical research, serious practitioner reflections located in peer-review publications, and a small number of articles that are explicitly devoted to methodological considerations, we are suggesting in this article that a distinctive sub-field of Muslim Chaplaincy Studies can now be identified.

Consciousness Under the Spotlight: The Problem of Measuring Subjective Experience.

The study of consciousness is considered by many one of the most difficult contemporary scientific endeavors and confronts several methodological and theoretical challenges. A central issue that makes the study of consciousness so challenging is that, while the rest of science is concerned with problems that can be verified from a "third person" view (i.e., objectively), the study of consciousness deals with the phenomenon of subjective experience, only accessible from a "first person" view. In the present article, we review early (starting during the late 19th century) and later efforts on measuring consciousness and its absence, focusing on the two main approaches used by researchers within the field: objective (i.e., performance based) and subjective (i.e., report based) measures of awareness. In addition, we compare the advantages and disadvantages of both types of awareness measures, evaluate them according to different methodological considerations, and discuss, among other issues, the possibility of comparing them by transforming them to a common sensitivity measure (d'). Finally, we explore several new approaches-such as Bayesian models to support the absence of awareness or new machine-learning based decoding models-as well as future challenges-such as measuring the qualia, the qualitative contents of awareness-in consciousness research.

Bibliometric Analysis of Platelet-Rich Plasma Treatment for Hair Restoration, Facial Rejuvenation, Dental Procedures, and Gynecological Rejuvenation

Introduction: Autologous platelet-rich plasma (PRP) technologies offer an attractive treatment option for various medical fields. Owing to its high concentration of growth factors, PRP has been posited to induce proliferation, differentiation, and angiogenesis at the cellular level, as well as wound-healing and remodeling at the tissue level. The goal of the present bibliometric analysis was to characterize the growing body of literature concerning PRP use in various medical applications. Methods: A comprehensive literature search was performed on June 28, 2024, using Web of Science and SCOPUS databases, covering all available publications in selected categories from 2001 to present. Results: PRP use for hair restoration had both the greatest number of total publications among the investigated applications, whereas PRP use in dental procedures had the longest-standing history of publications. PRP use in hair restoration and facial rejuvenation had the greatest number of placebo-controlled and double-blinded randomized controlled trials; however, the impact of results may suffer from a lack of consistency in PRP preparation and outcome measurement between different studies. Conclusion: To effectively validate the utility of PRP across various medical interventions, careful consideration of methodology should be undertaken for future studies to ensure validity of results.

Mixed Methods Research Centering on Minoritized Students in Higher Education: A Literature Review

AbstractThe increasing diversity among higher education students urges researchers to expand research methodologies beyond traditional quantitative approaches. A growing number of higher education researchers have employed mixed methods research (MMR) approaches in studies centering on minoritized student populations. In this review, we identified and analyzed 72 empirical MMR studies published between 2007 and 2023, describing the characteristics of the research design and focusing on the MMR design strategies employed by the authors. The review details specific MMR strategies, including methods for engaging participants, integrating quantitative and qualitative data, and advancing the research agenda that centers minoritized students. Based on the review, we discuss methodological considerations and offer recommendations for higher education professionals to advance more thoughtfully conscious, student-centered modes of knowledge production focusing on minoritized populations.

A script fogalma és gyakorlati alkalmazhatósága

The collection presents professional materials that draw attention to the applicability of the concept and theory of script to the analysis of the attitudes of individuals and social groups towards different issues. The materials presented illustrate that scripts are procedures, scenarios that people use in predetermined situations, and that these procedures are situation-dependent. The application of this approach from a rural development perspective is not yet widespread - it is more commonly used in the field of gender roles and sexual behaviour - but there are already rural sociological analyses that show how scripts can influence development experiments and existing practices. The examples and methodological considerations that can be found in the related literature can be interpreted and applied to the case of the Szeklerland, in relation to a range of social problems and groups.

Person-centered and qualitative approaches to network analysis in physics education research

Network analysis has become a well-recognized methodology in physics education research (PER), with study topics including student performance and persistence, faculty change, and the structure of conceptual networks. The social network analysis side of this work has focused on quantitative analysis of whole-network cases, such as the structure of networks in single classrooms. Egocentric or personal network approaches are largely unexplored, and qualitative methods are underdeveloped. In this paper, we outline theoretical and practical differences between two major network paradigms—whole-network and egocentric—and introduce theoretical frameworks and methodological considerations for egocentric studies. We also describe qualitative and mixed-methods approaches that are currently missing from the PER literature. We identify areas where these additional network methods may be of particular interest to physics education researchers and end by discussing example cases and implications for new PER studies. Published by the American Physical Society 2024

School District Discourse Coalitions and Equity-Focused Policy Innovations in Oakland, California 2020–2021

Purpose: To better understand how district leaders at urban school districts innovate and design policies, this study investigated how actors in one district, Oakland Unified School District, discussed ways to improve their education system at school board meetings during 2020 and 2021. Approach: The research used a case study approach to develop a process of inquiry, drawing on theoretical literature on innovation in social fields, empirical work on urban education reforms, and methodological considerations from critical social analysis techniques. It used a variety of qualitative methods to identify critical policy issues and policy innovations, and examined the way actors in two coalitions, each with a different approach to change, used discourse to convey their ideologies about racial equity and justice. Findings: District actors collaboratively designed and passed five innovative policies: school safety, remote learning, climate change, Black reparations, and mental health. While one group, the incumbent discourse coalition, focused attention on fiscal stability and closing underperforming schools, another, the challenger discourse coalition, conveyed strategies on improving schools and surrounding communities through new education policies. Though unexpected crises expedited innovation, the perspectives of the dominant culture were most privileged in the final designs of resolutions. Implications: By using broad theories and generalizable concepts this study shows how discourse in policymaking can be examined in other settings and illustrates ways similar school districts may innovate in their systems.

Developing a novel, systematic form of Media Framing Analysis to discursively examine the UK’s Employment and Support Allowance policy

ABSTRACT In 2008, the UK government introduced Employment and Support Allowance (ESA) as a welfare policy for individuals who are unable to work due to sickness or disability. Our research project examined the cultural landscape that has been made ‘available’ for those living with chronic health conditions whilst claiming welfare. To increase the transparency of a Foucauldian-inspired discursive analysis, PRISMA reporting guidelines were incorporated into a Media Framing Analysis. News articles and policy documents were collected as data corpora. This paper outlines how this innovative approach was developed; sharing samples of the analytical findings to illustrate what was achieved through a systematic compiling of a data set. A genealogical approach to health-based welfare shows how temporal and dualistic discourses of illness synonymise ‘health’ with a capability for employment. Methodological considerations are explored; illuminating how a systematic approach to data compilation can improve the transparency, rigour and potential transferability of discursive analyses.

Ethical and Methodological Considerations in LGBTQ-focused Online Ethnography: A Proposal of a Systematic Review

Lesbian, gay, bisexual, transgender, and queer (LGBTQ) people constitute a vulnerable population that requires research about their needs, representations, and challenges. Among the variant research methods, ethnography is particularly effective in understanding participants and their lived experience. The development of information and communication technologies has transformed traditional ethnography research and contributed to the emergence of online ethnography research that holds potential for studying vulnerable populations (e.g., LGBTQ people) and relevant topics. We propose a systematic review to explore how researchers have considered and addressed ethical and methodological issues in LGBTQ-focused online ethnography research. We used the core collection of the Web of Science to search for relevant literature. We crafted the search query based on studies of LGBTQ populations, online ethnography studies, and other data sources like the Homosaurus vocabulary. Two groups of search terms were compiled and used in combination, including population-related terms (e.g., “queer”, “LGB*”, “GLB*”, and “sexual minorit*”) and method-related terms (e.g., “online ethnograph*”, “netnograph*”, “digital ethnograph*”, and “virtual ethnograph*”). In this review, we focus on empirical journal articles using any type or variant of online ethnography to investigate LGBTQ-focused topics. The eligible articles may include LGBTQ people as participants or stakeholders (e.g., LGBTQ staff), or analyze LGBTQ-related content (e.g., YouTube videos). Most importantly, we will analyze the ethical concerns (e.g., informed consent, power imbalance, cultural sensitivity, and beneficence and justice) and methodological aspects (e.g., research design, sampling, recruitment, data collection, data analysis, and roles of LGBTQ people) of these studies.

In Search of the Causes of the Globalization Backlash: Methodological Considerations on Post-treatment Bias

We study the implications of post-treatment bias in the context of the globalization backlash. We discuss whether horse-race regressions can inform about the relative role of economic versus cultural drivers. We make three methodological points: (1) if and insofar as cultural variables are post-treatment with respect to economic factors, the estimates of the effect of economic shocks on voting are biased in regressions that include cultural controls (and vice versa); (2) for the same reason, such horse-race regressions do not allow to accurately estimate the relative role of economic versus cultural factors; (3) one cannot infer mediation effects from changes in regression coefficients for a given factor of interest before and after including post-treatment controls. We accompany the methodological discussion with empirical evidence on the relevance of post-treatment bias in studies of the globalization backlash, both by replicating and expanding on earlier studies, and by presenting novel cross-country results on the culture-economy nexus.

An fMRI study of phrase structure and subject island violations.

In principle, functional neuroimaging provides uniquely informative data in addressing linguistic questions, because it can indicate distinct processes that are not apparent from behavioral data alone. This could involve adjudicating the source of unacceptability via the different patterns of elicited brain responses to different ungrammatical sentence types. However, it is difficult to interpret brain activations to syntactic violations. Such responses could reflect processes that have nothing intrinsically related to linguistic representations, such as domain-general executive function abilities. In order to facilitate the potential use of functional neuroimaging methods to identify the source of different syntactic violations, we conducted an fMRI experiment to identify the brain activation maps associated with two distinct syntactic violation types: phrase structure (created by inverting the order of two adjacent words within a sentence) and subject islands (created by extracting a wh-phrase out of an embedded subject). The comparison of these violations to control sentences surprisingly showed no indication of a generalized violation response, with almost completely divergent activation patterns. Phrase structure violations seemingly activated regions previously implicated in verbal working memory and structural complexity in sentence processing, whereas the subject islands appeared to activate regions previously implicated in conceptual-semantic processing, broadly defined. We review our findings in the context of previous research on syntactic and semantic violations using event-related potentials. Although our results suggest potentially distinct underlying mechanisms underlying phrase structure and subject island violations, our results are tentative and suggest important methodological considerations for future research in this area.

Methodological concerns underlying a lack of evidence for cultural heterogeneity in the replication of psychological effects

The multi-site replication study, Many Labs 2, concluded that sample location and setting did not substantially affect the replicability of findings. Here, we examine theoretical and methodological considerations for a subset of the analyses, namely exploratory tests of heterogeneity in the replicability of studies between “WEIRD and less-WEIRD cultures”. We conducted a review of literature citing the study, a re-examination of the existing cultural variability, a power stimulation for detecting cultural heterogeneity, and re-analyses of the original exploratory tests. Findings indicate little cultural variability and low power to detect cultural heterogeneity effects in the Many Labs 2 data, yet the literature review indicates the study is cited regarding the moderating role of culture. Our reanalysis of the data found that using different operationalizations of culture slightly increased effect sizes but did not substantially alter the conclusions of Many Labs 2. Future studies of cultural heterogeneity can be improved with theoretical consideration of which effects and which cultures are likely to show variation as well as a priori methodological planning for appropriate operationalizations of culture and sufficient power to detect effects.

From Consoles to Classrooms: Preliminary Insights About Pre-Service Teachers and Video Games

Integrating video games into the classroom is a promising way to enhance learning experiences, as the market of serious games is expanding. European schools are investing in digital equipment, and the use of educational video games is technologically viable. Nonetheless, actual experiences of video games in class are still rare. A key gap to be explored is understanding how pre-service secondary teachers perceive and are prepared to use digital games in their future classrooms. Do they think it would enhance their teaching and their students’ learning? Do they feel prepared for it? To answer these questions, and possibly address future challenges, we conducted a comprehensive study with students at Zurich University of Teacher Education (PHZH). The research process began with the development and testing of a detailed questionnaire that focused on participants' personal gaming behaviour, preferences, and perceptions of the educational potential of video games. Key areas such as serious games, game design, gamification, game-based learning, and game culture were explored to assess the relevance and understanding of these concepts in an educational context. This paper explains the development and structure of the questionnaire as a measurement instrument as well as the underlying literature and methodological considerations. The first implementation and the preliminary survey with 48 PHZH students are presented, and the practicability and reliability of the questionnaire are evaluated. The result of the survey suggests pre-service teachers are generally positive about integrating video games and game design into the classroom, yet enthusiasm is not enough without additional support.

Language teacher expertise research: A theoretical case and research agenda

Abstract Expertise exists among all communities of educational practitioners at all levels and in all national contexts. By identifying expert practitioners, learning from them and valuing their professional competence, researchers can support, promote and build upon sustainable, embodied, holistic models of quality in ways that have direct relevance for the classroom, the curriculum and wider educational goals. Yet, despite its potential as a field of research, there have been relatively few studies involving expert language teachers to date. After a brief historical background, this article makes the case for language teacher expertise research, noting its high ecological validity, its great practical utility, its ability to bridge the research–practice divide and its potentially positive impact on teaching communities. Key methodological considerations are also discussed, including defining expertise, identifying expert teachers and looking beyond the limits of subject-specific pedagogy to understand the whole practitioner in their sociocultural context. The article then proposes a framework for future teacher expertise research that spans diverse methodologies. Six example research tasks from within this framework are proposed, each justified and exemplified, incorporating suggestions for research design that are intended to encourage both experienced and novice researchers to engage with teacher expertise as a promising domain for future investigation.

Prediction of craving across studies: Acommentary on conceptual and methodological considerations when usingdata-driven methods.

Craving is a central feature of substance use disorders and disorders due to addictive behaviors. Considerable research has investigated neural mechanisms involved in the development and processing of craving. Recently, connectome-based predictive modeling, a data-driven method, has been used in four studies aiming to predict craving related to substance use, addictive behaviors, and food. Studies differed in methods, samples, and conceptualizations of craving. Within the commentary we aim to compare, contrast and consolidate findings across studies by considering conceptual and methodological features of the studies. We derive a theoretical model on the functional connectivity-craving relationships across studies.

Comparing three common nest survey methods, using double-crested cormorants as a proposed sentinel for monitoring plastic pollution in freshwater environments

Many bird species use plastic as nest-building material, and nest surveys represent a unique opportunity to monitor environmental plastic pollution. However, the current literature lacks consistent, repeatable methodologies, making comparison across studies challenging. This study evaluated three common nest survey methods to assess the use of nest debris: photographic assessment, visual assessment, and nest deconstruction. We applied these methods to double-crested cormorant nests (Nannopterum auritum) at two locations on Lake Ontario, Canada. We found that for this species, nest deconstruction yielded the greatest accuracy and detail for detecting debris abundance, type, and colour. Of the two non-invasive methods, visual surveys outperformed photographic surveys across all metrics assessed. In our mainland colony, 100% of nests contained debris based on visual assessment, while at our offshore colony only 37.4% of nests contained debris, suggesting that location influences nest debris for this species. We detected Personal Protective Equipment (PPE)-related debris in 20% of all nests across survey years at our mainland colony (2022 and 2023), representing the first time that PPE has been documented in the nests of this species and demonstrating that nest surveys can be a useful tool for capturing changes in an evolving pollution landscape. This study contributes evidence that double-crested cormorants may be a useful sentinel species for monitoring plastic pollution in understudied, freshwater environments. Our results also demonstrate that the chosen method can greatly impact the results of a nest survey, and careful consideration of methodology should be undertaken before implementing a nest survey to monitor plastic pollution.

Exploring Young Adults' Mental Health Help‐Seeking Journey: Preliminary Findings on Resource Navigation Behavior

ABSTRACTYoung adults are among the most vulnerable populations susceptible to mental health concerns, yet they encounter various barriers in accessing resources and obtaining necessary support and treatment. While prior research has predominantly focused on technology utilization in mental health help‐seeking, a more comprehensive understanding of how individuals navigate the broader landscape of available resources is crucial. To address this gap, we conducted in‐depth interviews with 18 young adults to explore their lived experiences and resource navigation during the mental health help‐seeking process. Guided by the Social‐Ecological Framework, our study categorized the resources utilized by young adults into four categories: technological, interpersonal, community‐based, and societal. Through thematic analysis, we report preliminary findings that identify specific characteristics of resources that young adults value and prioritize throughout their help‐seeking journey. These findings provide implications for designing multi‐level mental health resources and interventions to facilitate young adults' help‐seeking. We also discuss methodological considerations to encourage in‐depth conversations with marginalized groups on sensitive topics like mental health, emphasizing the importance of creating a safe, non‐judgmental space for participants to share their experiences openly.

Evaluating interaction energy versus electron density relationships to estimate inter and intramolecular H-bonding

We investigate the computational effects on the relationships between interaction energy (ΔE) and electron density (ρ), at the critical point obtained from 19 intermolecular H-bonded dimers, to estimate inter and intramolecular interactions of larger H-bonded systems. Our analysis examines basis set superposition error (BSSE) effects, dispersion energy corrections, and the exchange-correlation energy model on the ΔE vs. ρ linear regressions. The calculations were carried out within density functional theory (DFT) combined with the 6-31+G(d,p) and def2-TZVPP basis sets. This procedure quantifies the average effects of BSSE for different levels of approximation, and underscore the sensitivity of the ΔE estimation together with dispersion corrections. This is valuable for the development of DFT-based estimators of multiple interaction energies of large H-bonded systems with low computational cost. We have applied this procedure by analyzing H-bonded biological molecules, such as DNA base pairs, an asparagine side chain, and an AZT molecule. Our estimated H-bond interaction energies are in agreement with previous studies, and emphasize the importance of methodological considerations for accurately predicting interaction energies using DFT combined with topological parameters.