Methodological Considerations Research Articles

Systematic Review Procedures for the World Health Organization (WHO) Evidence Syntheses on Benefits and Harms of Structured and Standardized Education/Advice, Structured Exercise Programs, Transcutaneous Electrical Nerve Stimulation (TENS), and Needling Therapies for the Management of Chronic Low Back Pain in Adults.

As commissioned by the WHO, we updated and expanded the scope of four systematic reviews to inform its (in development) clinical practice guideline for the management of CPLBP in adults, including older adults. Methodological details and results of each review are described in the respective articles in this series. In the last article of this series, we discuss methodological considerations, clinical implications and recommendations for future research.

Viral Diversity in Benthic Abyssal Ecosystems: Ecological and Methodological Considerations.

Viruses are the most abundant 'biological entities' in the world's oceans. However, technical and methodological constraints limit our understanding of their diversity, particularly in benthic abyssal ecosystems (>4000 m depth). To verify advantages and limitations of analyzing virome DNA subjected either to random amplification or unamplified, we applied shotgun sequencing-by-synthesis to two sample pairs obtained from benthic abyssal sites located in the North-eastern Atlantic Ocean at ca. 4700 m depth. One amplified DNA sample was also subjected to single-molecule long-read sequencing for comparative purposes. Overall, we identified 24,828 viral Operational Taxonomic Units (vOTUs), belonging to 22 viral families. Viral reads were more abundant in the amplified DNA samples (38.5-49.9%) compared to the unamplified ones (4.4-5.8%), with the latter showing a greater viral diversity and 11-16% of dsDNA viruses almost undetectable in the amplified samples. From a procedural point of view, the viromes obtained by direct sequencing (without amplification step) provided a broader overview of both ss and dsDNA viral diversity. Nevertheless, our results suggest that the contextual use of random amplification of the same sample and long-read technology can improve the assessment of viral assemblages by reducing off-target reads.

A data mining approach for determining biomechanical adaptations in runners who experienced and recovered from patellofemoral pain syndrome

ABSTRACT Patellofemoral pain (PFP) is a common musculoskeletal pain disorder experienced by runners. While biomechanics of those with PFP have been extensively studied, methodological considerations may omit important adaptations exhibited by those experiencing and recovered from pain. Instead of a priori selection of discrete biomechanical variables, a data mining approach was leveraged to account for the high dimensionality of running gait data. Biomechanical data of runners symptomatic for, recovered from, and who had never experienced PFP were collected at the 1st (M1) and 21st (M21) minutes of a treadmill run. Principal component analysis and a logistic regression model were used to classify healthy and symptomatic runners, and a feature ranking process determined the important features. The M1 model achieved an accuracy of 82.76% with features related to knee flexion angle, hip abduction moment and gluteus maximus activation, while the M21 model required an additional nine features to achieve an accuracy of 79.31%. Data for recovered runners were projected onto the models, resulting in five and seven out of twelve symptomatic classifications at M1 and M21, respectively. Following the onset of pain, a greater number of features were required to classify runners with PFP, suggesting they may experience individual pain adaptation strategies.

The vulgarization hypothesis and the translation of swearwords by male and female translators in AVT in Spain

This article aims to test the vulgarization hypothesis in audiovisual translation (AVT) with regards to possible differences between male and female translators’ practices. It starts with an overview of the most recent publications on swearing and AVT, and of studies that have analyzed the use of swearwords by male and female speakers. Two seasons of these police dramas were used for the study. Both were produced by the same team at approximately the same time. After some methodological and theoretical considerations, the article presents and analyzes the translational choices made by the female translators (F) of Chicago PD and the male translator (M) of FBI. The results confirm the vulgarization hypothesis in AVT in both series, although the tendency in (F) Chicago PD is to use a greater number of swearwords than in (M) FBI.

Activity reconstruction of Rangifer tarandus feet in Fennoscandian -archaeology: Methodological considerations and application to archaeological material from two Sámi habitation sites

ObjectiveThis study explores the presence and prevalence of working Rangifer tarandus tarandus (domestic reindeer) through entheseal changes present in Rangifer tarandus phalanges at the Sámi habitation sites of Juikenttä and Nukkumajoki, located in Finland and dating from the 14th to the 18th centuries. MaterialsModern samples (n = 23 phalanges, Rangifer tarandus fennicus; n = 60 phalanges, Rangifer tarandus tarandus non-working; n = 72 phalanges, Rangifer tarandus tarandus working) with known life histories. Archaeological samples (n = 22 phalanges, Juikenttä; n = 118 phalanges, Nukkumajoki). MethodsWe analysed entheseal changes on the first and second phalanges of both the thoracic and pelvic limbs. The minute movements of reindeer feet create entheseal changes which are specific to different activity patterns. This analysis was compared to the results obtained from long-bone analysis. ResultsOur results show the presence of working reindeer at both sites and are consistent with previous analysis of the long bones found at the site. ConclusionsThis archaeological application of phalangeal entheseal changes suggests that reindeer phalanges may be used to assess both the presence and proportion of working animals in an assemblage. SignificanceThis study provides more evidence for the use of working reindeer as early as the 14th century in Northern Finland. This work also helps to provide archaeological evidence for Sámi subsistence patterns, as well as proving new tools for zooarchaeological assessment. LimitationsSmall sample size and taphonomy may affect assessment. Additionally, entheseal changes take time to envelope and may under-represent the number of working reindeer. Suggestions for further researchAssessment of additional modern and archaeological samples.

A Content Analysis of English Textbook “English For Nusantara” for 7 Grade Junior High School in Kurikulum Merdeka

This study aims to analyze English textbook entitled English for Nusantara for grade 7 junior high school students at the Kurikulum Merdeka and to find out all the strengths and the weaknesses of this book in the items aims and approach, language content, skills, topic, methodology, and practical consideration determined by Cunningsworth's theory (1995). The method used in this study is a qualitative descriptive method with content analysis and literature study. The subjects in this study are the 5 chapters contained in the English for Nusantara textbook. In collecting data, the writer makes a table and evaluates each item determined from Cunningsworth's theory (1995). In data analysis techniques, the percentage of item fulfillment is calculated by dividing the total criteria met by the total number of criteria for each item then multiplied by 100%. Then determine the strengths and the weaknesses of each of these items. The results of this study indicate that the English textbook English for Nusantara fulfills an average of 94% in the "Good" category with items aims and approach (100%), language content (66.67%), skills (100%), topic (100%), methodology (100%), and practical consideration (100%) and has its strengths and weaknesses inside.

The relationship between entrepreneurial intention and behavior: A meta-analytic review

A vibrant literature studying antecedents of entrepreneurial intentions is largely motivated by an often implicit assumption that they will be followed by subsequent entrepreneurial behaviors or actions. A much smaller number of studies actually test this assumption. Their results suggest that while the entrepreneurial intention–behavior relationship is usually present, its strength turns out highly contextual. This meta-analysis intends to integrate and summarize the available research base on the entrepreneurial intention–behavior relationship, assessing the moderating impacts of environmental, demographic and methodological factors. Data from 75 studies (150,703 individuals) were included in the analysis. Our results indicate that the focal relationship is robust across environmental contexts, populations, and methodologies except for the measures used for entrepreneurial behavior, the use of a database compared to collecting new data, and the duration of time between intention and behavior. Additionally, entrepreneurial intentions were found to account for only 17% of the variance in entrepreneurial behaviors as opposed to the commonly expected and cited 37%. Our findings suggest theoretical and methodological considerations for future work aimed at exploring and overcoming the non-trivial intention–behavior gap and we encourage the discovery of cognitive and behavioral factors reinforcing the intention–action translation at different levels of analysis and over time.

A longitudinal view of an approach to responsiveness: Principles followed and lessons learned

Responsiveness is currently a hot topic in the psychotherapy literature with a large variation in what the term means to colleagues of various orientations. This adds to its popularity but limits the scope of whatever is written or said about responsiveness. The fact that the meaning of responsiveness has developed over time within the approaches adds also to the variation, while an understanding of development has the potential of deepening the understanding of each approach. As a fair description and comparison of even just the most important approaches is by far out of reach for a page-limited article, the development of one approach, which may be termed the “Bernese” approach is described here, along with lessons learnt and general comments. The approach includes Plan Analysis case formulations, the concept of complementary or Motive-Oriented Relationship, a description of a combined qualitative and quantitative assessment, and many methodological and conceptual considerations. Personal development is woven in. Overall, it seems fair to say that this approach, at its core developed long before responsiveness became popular, has turned out to still be useful, with a gain in depth as far as concepts and assessment are concerned.

Mysterium Corpus: The Solo Piano Music of Alexander Scriabin

This article introduces the Mysterium corpus, the complete published oeuvre of Alexander Scriabin’s 207 solo piano works, and makes the corpus available in Humdrum’s kern format. Scriabin’s music presents distinct challenges, specifically in relation to his use of complex rhythmic and metric explorations and the idiosyncratic ways in which he notated his compositional ideas. While this sidetdataset is focused on Scriabin, the methodological challenges explored in the article may shed light on the encoding process for other related late-tonal and early post-tonal repertoires. As such, this article provides a case study of methodological considerations involved in systematically translating messy musical notations into a symbolic encoding of the musical data. Finally, this article provides descriptive statistics of the corpus, especially focusing on Scriabin’s treatment of meter and two harmonies (i.e., the dominant-seventh chord with lowered fifth, and the “Mystic” chord), and discusses the applicability of the Mysterium corpus for future research.

Trends and challenges within Reddit and health communication research: A systematic review

There is a growing body of health communication literature addressing health-related discourse across user-generated platforms. Specifically, Reddit, the 19th most visited website in the world, serves as a promising venue for understanding communication surrounding health concerns. Such studies apply a variety of theories and methodological approaches, analyze large corpora, and build predictive and descriptive models for public health communication. The current study investigates health communication literature in the context of Reddit, identifying major topics, theories, and methods employed across studies, as well as how health communication topics have evolved over time. We identify future research directions, proposing theoretical and methodological considerations as well as issues and practices to employ when researching health phenomena via social platforms.

Using Multisource High-Resolution Remote Sensing Data (2 m) with a Habitat–Tide–Semantic Segmentation Approach for Mangrove Mapping

Mangrove wetlands are hotspots of global biodiversity and blue carbon reserves in coastal wetlands, with unique ecological functions and significant socioeconomic value. Annual fine-scale monitoring of mangroves is crucial for evaluating national conservation programs and implementing sustainable mangrove management strategies. However, annual fine-scale mapping of mangroves over large areas using remote sensing remains a challenge due to spectral similarities with coastal vegetation, tidal periodic fluctuations, and the need for consistent and dependable samples across different years. In previous research, there has been a lack of strategies that simultaneously consider spatial, temporal, and methodological aspects of mangrove extraction. Therefore, based on an approach that considers mangrove habitat, tides, and a semantic segmentation approach, we propose a method for fine-scale mangrove mapping suitable for long time-series data. This is an optimized hybrid model that integrates spatial, temporal, and methodological considerations. The model uses five sensors (GF-1, GF-2, GF-6, ZY-301, ZY-302) to combine deep learning U-Net models with mangrove habitat information and algorithms during low-tide periods. This method produces a mangrove map with a spatial resolution of 2 m. We applied this algorithm to three typical mangrove regions in the Beibu Gulf of Guangxi Province. The results showed the following: (1) The model scored above 0.9 in terms of its F1-score in all three study areas at the time of training, with an average accuracy of 92.54% for mangrove extraction. (2) The average overall accuracy (OA) for the extraction of mangrove distribution in three typical areas in the Beibu Gulf was 93.29%. When comparing the validation of different regions and years, the overall OA accuracy exceeded 89.84% and the Kappa coefficient exceeded 0.74. (3) The model results are reliable for extracting sparse and slow-growing young mangroves and narrow mangrove belts along roadsides. In some areas where tidal flooding occurs, the existing dataset underestimates mangrove extraction to a certain extent. The fine-scale mangrove extraction method provides a foundation for the implementation of fine-scale management of mangrove ecosystems, support for species diversity conservation, blue carbon recovery, and sustainable development goals related to coastal development.

How within-person research can extend marketing knowledge

Much existing research in marketing examines theory using between-persons research designs, yet draws implications that are based on within-person causal logics. This mismatch is problematic in developing marketing knowledge, and in impacting marketing practice effectively. The present article discusses the importance of conducting within-person research in marketing, alongside suggesting marketing constructs that could benefit from within-person analyses. We provide details on how to conceptualize within-person theories, and compare them with the more common between-persons approach. Furthermore, a set of important methodological considerations and recommendations for designing within-person studies is elaborated on, and theoretical and empirical principles are applied to an empirical demonstration. The results show how theories and relationships can sometimes differ across levels, but in other instances can remain consistent. We draw out a set of important implications and directions for future marketing research, and encourage researchers to incorporate within-person approaches into their toolkit of theoretical and empirical methods.

Aging and Sympathetic Transduction to Blood Pressure in Humans: Methodological and Physiological Considerations.

Recent reports suggest that quantification of signal-averaged sympathetic transduction is influenced by resting muscle sympathetic nerve activity (MSNA) and burst occurrence relative to the average mean arterial pressure (MAP). Herein, we asked how these findings may influence age-related reductions in sympathetic transduction. Beat-to-beat blood pressure and MSNA were recorded during 5-minutes of rest in 27 younger (13F, age: 25±5 yrs, BMI: 25±4 kg/m2) and 26 older (15F, age: 59±5 yrs, BMI: 26±4 kg/m2) healthy adults. All MSNA bursts were signal-averaged together. Beat-to-beat MAP values were then split into low (T1), middle (T2), and high (T3) tertiles, and signal-averaged transduction was calculated within each tertile. Resting MSNA was higher in older adults and MAP was similar between groups. Older adults exhibited blunted overall MAP transduction (Younger: Δ1.5±0.6 vs. Older: Δ0.9±0.7 mmHg, P=0.005), which was irrespective of relation to prevailing MAP. A greater proportion of bursts occurred above the average MAP in older adults (P<0.001), and a larger proportion of these bursts were associated with depressor responses (P=0.005). Nonetheless, assessment of bursts above the average MAP associated with pressor responses revealed similar age-associated reductions in transduction (Younger: Δ2.6±1.6 vs. Older: Δ1.7±0.8 mmHg, P=0.016). These findings indicate an age-related increase in burst occurrence above the average resting MAP, which alone does not explain blunted transduction, thereby supporting physiological underpinnings of age-related decrements in sympathetic transduction to blood pressure.

An introduction to carrying out and appraising systematic reviews in healthcare

Systematic literature reviews remain one of the most trusted sources of evidence used to inform policy and clinical decision-making. The proliferation of academic publications makes reviews increasingly essential to practitioners and policy makers as they enable them to rapidly access high-quality evidence synthesised from multiple sources. Knowledge and awareness of the structure and components of a systematic review can aid in the production of high-calibre reviews and improve the ability to appraise their quality. An overview of the main stages of carrying out a review is presented here along with frameworks and methodological considerations that will aid those producing or appraising systematic reviews.

Ethnic-Racial Socialization in Transracially Adoptive Families: Foundational Review and Educational Implications

While all families are responsible for the ethnic-racial socialization of their children, this process represents a nuanced undertaking for parents who have adopted transracially. Following the model of change (Mace, 1981), this paper first presents a review of the socialization and transracial adoption literature with a special focus on intrinsic and extrinsic factors shaping how children are socialized, followed by a set of practical strategies for adoptive parents and practitioners to use with the goal of empowering parents to take on the task of socialization confidently and effectively. Methodological considerations relevant for scholars studying ethnic-racial socialization are also included.

How low can you go?: Methodologic considerations in clonal hematopoiesis variant calling

Clonal hematopoiesis (CH) is defined by the presence of an expanded clonal hematopoietic cell population due to an acquired mutation conferring a selective growth advantage and is known to predispose to hematologic malignancy. In this review, we discuss sequencing methods for CH detection in bulk sequencing data and corresponding bioinformatic approaches for variant calling, filtering, and curation. We detail practical recommendations for CH calling. Finally, we discuss how improvements in CH sequencing and bioinformatic approaches will enable the characterization of CH trajectories, its impact on human health, and therapeutic approaches to mitigate its adverse effects.

Methodological considerations and reflection on using online photo-elicitation techniques to explore students’ professional doctorate journey

ABSTRACT In this methodological discussion, a critical and reflective account of the process and use of online photo-elicitation interviews is given. The role and importance of a well-structured pre-interview task are discussed with a working example aiming to capture physiotherapy students’ professional doctorate journey. It is argued that photo-elicitation techniques can increase active participation and enhance participants’ storytelling by encouraging the use of abstract thinking. This article also offers unique insights through the researcher’s reflective diary and direct quotes from the participants. Key considerations and practical recommendations are provided, such as the online application of photo-elicitation, the nature of the observed topic and working with and not alongside the pictures. Overall, this article is intended to further contribute to the literature on the evaluation and implementation of photo-elicitation techniques, especially in an online setting.

Methodological considerations for collecting and analyzing data on multiply marginalized psychology trainees with disabilities.

Historically, psychology trainees from marginalized communities have been underrepresented both as researchers and as participants in research on trainee experiences and outcomes. The current research can be used to develop evidence-based strategies to understand and improve the recruitment, retention, advancement, and overall training experiences of trainees with marginalized identities. We review the existing literature on the experiences of psychology trainees, particularly that focused on trainees from marginalized backgrounds. Quantitative, qualitative, and archival data collection and analysis methods each carry their own benefits and limitations, which must be considered and addressed intentionally to optimize the impact of research findings for multiply marginalized individuals. Mixed methods approaches are also discussed. Matching each limitation with a research design strategy is recommended, including the use of sample weights from population archival data to contextualize sample results, incorporating flexibility for reasonable accommodations for intensive qualitative studies, and other strategies. We provide guidance on selecting a methodology based on specific research and dissemination goals within this area and discuss implications and recommendations for both rehabilitation psychology specifically and the field more broadly. Training programs, governing bodies, faculty, researchers, and other invested parties have shared accountability to deliver diverse, equitable, and inclusive education and training experiences, and conducting high-quality research on the experiences of multiply marginalized trainees, including those with disabilities, is a key component of that process. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

12 AppReminders - A pilot feasibility randomised controlled trial of a memory aid app for people with acquired brain injury

Objective:Mobile phone reminding apps can be used by people with acquired brain injury (ABI) to compensate for their memory impairments. However off-the-shelf apps may be difficult to use. ApplTree has been developed to be accessible to this group, compared to off-the-shelf reminding apps such as Google Calendar. This pilot feasibility trial aimed to establish the feasibility of running (and issues that should be addressed to complete) a randomised controlled trial comparing ApplTree to Google Calendar in an ABI community treatment setting.Participants and Methods:Adults with self or other reported memory difficulty after an ABI were enrolled (n=39). Those who completed the baseline phase were randomised (n=29) and randomly allocated to the Google Calendar or ApplTree intervention. They were shown a 30 minute video tutorial of the app and an assessment on their ability to use it. Timely completion of everyday memory tasks were measured for a 3 week pre-intervention baseline and 3 week post-intervention follow-up phase. Participants also completed neuropsychological tests assessing memory, attention and executive function and gave qualitative feedback on the app and their experience in the trial.Results:Recruitment rate was 58% of the target (29 were randomised, n=50 was the target in 2 years). Retention rate was 65.5% and adherence rate was 57.9%. While the feasibility trial was not powered to calculate efficacy, there was a 13% increase in everyday memory tasks completed on time for those in the ApplTree group (n=10) compared to baseline and no change for the Google Calendar group (n=9). Feasibility results indicate 72 participants would need to fully complete a trial to detect the minimum clinically important difference (12.5% increase in successful performance of everyday memory tasks) in the efficacy of ApplTree compared to Google Calendar, should such a difference exist.Conclusions:The challenges with recruitment of people receiving community care for ABI are highlighted in this trial and discussed along with the impact of the Covid-19 pandemic. Methodological considerations for researchers or clinicians looking to measure everyday memory ability are discussed. The majority (19 of 21) of participants who were given an app were capable of learning to use it during an hour-long session. This indicates it is a feasible intervention that community ABI services could offer. Participant feedback highlighted the merits of design features implemented in ApplTree that can improve the uptake and utility of reminding apps.

Resilience science: Theoretical and methodological directions from the juncture of resilience and projects

Increasing concerns about disruptions and the need for adaptation to drastic changes in social and ecological systems is reflected in the growing interest in resilience science. At the same time, the surge in medium to large scale projects around the world, known as projectification of societies, has resulted in considerable interest in the discipline of project studies. The disciplinary idiosyncrasies of project studies motivate a reflection on theoretical and methodological considerations in resilience science. This reflection rests on the experience of instigating research at the juncture of resilience and projects in this special collection. Specifically, we framed these observations as a set of principles that can inform resilience science, including the need for theoretical parsimony, deliberate attention to system boundaries in conceptualization of resilience, as well as critical considerations in measuring resilience. We posit that in its essence, project studies has to navigate a paradox through: (i) investigating projects as efficient form of organizing for a resilient, sustainable and just future, while (ii) unpacking the governance and accountability limitations of temporary organizing within projects that aim to ensure these long-term goals. The proposed principles are core to the broader research stream that we call “projects of future,” a collective inquiry to unpack these paradoxes and a research stream to engage project scholarship with the contemporary phenomena in Anthropocene.