Blended learning, a pedagogical approach that integrates traditional face-to-face teaching with online learning activities, has garnered significant attention in educational research. This systematic literature review examines the effective strategies of blended learning in educational settings. The study identifies various strategies, analyzes their effectiveness in enhancing student learning outcomes, and provides recommendations for educators on the use of the most effective blended learning strategies. The review reveals that well-designed blended learning strategies, tailored to student characteristics, incorporating active learning methods, diverse pedagogical approaches, and rapid feedback mechanisms, significantly improve student learning outcomes across various levels of education. The findings underscore the importance of carefully implementing and evaluating blended learning strategies to maximize their benefits in educational settings.