AbstractA method of density measurement for substances that are isentropically compressed up to megabar pressures is described in the paper. Measurement results for condensed hydrogen isotopes and aluminum are presented. These results, afterwards, are used for construction of hydrogen isotopes “cold” isentropes. Experimental x‐ray images of the facilities with the hydrogen isotopes, compressed up to several megabars are presented in the paper (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)