Methionine Hydroxy Analogue Free Acid Research Articles

Kinetics of hydrolysis of dimeric and trimeric methionine hydroxy analog free acid under physiological conditions of pH and temperature

Kinetics of hydrolysis of dimeric and trimeric methionine hydroxy analog free acid under physiological conditions of pH and temperature

A Comparison of Methionine Sources for Broiler Chickens Fed Corn-Soybean Meal Diets Under Simulated Commercial Grow-Out Conditions

Two experiments, involving 5,760 birds each, were conducted under simulated commercial grow-out conditions to determine the relative response of broiler chicks to two supplemental levels each of DL-methionine (DL-MET), L-methionine (L-MET), and methionine hydroxy analogue-free acid (MHA-FA) fed on an equimolar basis in corn-soybean meal diets. MHA-FA was shown to support 49-day weight gains comparable to those of chicks fed DL-MET, and both sources were superior to L-MET in this regard. However, there were no significant differences due to MET sources in the efficiency of feed utilization. When compared to basal-fed chicks, birds fed supplemental L-MET, DL-MET, or MHA-FA had elevated plasma free MET levels, whereas cyst(e)ine and taurine concentrations were not affected by dietary treatment. There were no effects of diet on either mortality or the incidence of leg abnormalities. The results of these studies suggest that MHA-FA is an acceptable source of MET for broiler chicks fed corn-soybean meal diets from day-old to market weight.

Comparison of DL-Methionine, DL-Methionine-Na, DL-Methionine Hydroxy Analogue-Ca, and DL-Methionine Hydroxy Analogue Free Acid in Broilers by Using a Crystalline Amino Acid Diet

The biological methionine activity of DL-methionine, DL-methionine-Na, the calcium salt of methionine hydroxy analogue (DL-MHA-Ca), and methionine hydroxy analogue free acid (DL-MHA-FA) was studied in a chick feeding test by using a crystalline amino acid basal diet. DL-Methionine and DL-methionine-Na were, as measured by gain and feed conversion efficiency, equally effective methionine sources on an equimolar basis. Performance of the chicks fed the DL-MHA-Ca supplemented diets was distinctly inferior to those fed equimolar quantities of DL-methionine. From our results, it was deduced that the biological activity of DL-MHA-Ca was approximately 81% that of DL-methionine on an equimolar basis, which is 67% on a weight basis of the commercial product. The poorest results were obtained with DL-MHA-FA as a methionine source. The DL-MHA-FA was only 76% as effective as DL-methionine on an equimolar basis, which is 66% by weight of the commercial product used.

Effectiveness of the Free Acid of Methionine Hydroxy Analogue as a Methionine Supplement in Broiler Diets

A liquid methionine supplement known as methionine hydroxy analogue-free acid (MHA-FA) was evaluated as a source of methionine in the diet of young broiler chicks. Diets calculated to be deficient in methionine were supplemented with MHA-FA and performance compared to that obtained when comparable diets were supplemented with molar equivalents of methionine from L-methionine, DL-methionine, or the calcium salt of methionine hydroxy analogue. Performance of chicks fed the test product was equal to that obtained on the other methionine products. The use of MHA-FA might allow for a more even distribution in the diet, easier handling, and a lower manufacturing cost with resultant savings in the cost of producing poultry and eggs.