Methamphetamine-induced Increase Research Articles

P-195 - Circadian variation in methamphetamine-induced increase in ambulatory activity in mice

P-195 - Circadian variation in methamphetamine-induced increase in ambulatory activity in mice

Possible Mode of Antidepressive Action of Imipramine

Imipramine augmented and prolonged methamphetamine-induced increases in the rate of responding of rats working for "rewarding" hypothalamic and midbrain stimulation. In contrast, chlorpromazine antagonized the effects of methamphetamine on self-stimulation. These opposite psychopharmacological effects are consistent with the different clinical effects of these drugs and suggest a mechanism for the antidepressive action of imipramine.