Creep-fatigue interaction (CFI) behavior of 9Cr-1.8W-0.5Mo-VNb steel (Grade 92 steel) base metal and its weld joint has been investigated at 823 K using a constant strain rate of 3 × 10–3 s−1. Both the base metal and the weld joint exhibited continuous softening with an almost equal cyclic stress response. The fatigue life decreased with increasing hold time. The hold applied in the compressive peak strain proved more deleterious compared to the tensile hold, indicating a compressive dwell sensitivity. Besides, the weld joints showed a greater reduction in fatigue life compared to the base metal. Fracture surfaces of the tested specimens revealed the prevalence of secondary cracks and extensive oxidation in the material. Weld joint specimens failed in the base metal region in all the tests. Evidence of dynamic strain aging in the form of serrations in the stress-strain hysteresis loops was also noted.