Wireless Sensor Networks have turned into a principal determination of various critical applications, like, target following, modern robotization, and message transformation etc. Commonly, a WSN comprises of an extensive number of small, low-cost sensor hubs that are conveyed in the target range for gathering information of intrigue. But, secure data packets transmission is the main critical issue –− + in this network because WSNs vulnerable to malicious attacks such as black hole and warm hole. In this paper, Hybrid Anomaly Detection Systems (HADS) called as Artificial Immune System is proposed in the WSNs. In this framework, developinga novel intrusion detection algorithm using Hybrid Tissue Growing Algorithm (HTGA) for identifying theanomalies presence cell and efficiently the communication tissue structure for transmitting the data packets is done. This algorithm is applied into two different developments such as Networked Tissue Growing (NTG) model and the Swarm Tissue growing (STG) algorithm. Both are autonomous in the capacity to create cautions in term of recognizing abnormalities in the route sections. The complexity calculation is primary nature depends onthe number of entry in the neighbor table and route discovery. If the tissue, predicts a week cell and then automatically rejects that cell for preventing from an intruder. The network based calculation expressly keeps up the cell in a dynamic clustering nature. This paper intends to make a relevantly mindful IDS by joining the idea of tissues, which will gives a more vigorous, versatile and precise security against assaults in interloper assaults in the sensor network. The simulation results of the proposed HADS technique is compared with the existing techniques such as LDTS, EED-M, and the NTMS-DS. Hence, the proposed HADS framework achieves greater performance than the existing methods.