The Igbo tribe of eastern Nigeria take the lead in expressing that mental health disorders are products of metaphysical machination or unwholesome practice which originated principally from various spiritual/metaphysical causations such as: - punishment from God or gods, evil eyes of the enemies, violation of certain customs, spirit/demonic possession, evil manipulations, sorcery, disturbances in social relations, dependence on drug substances and natural causes. In fact, the Igbo teaching on mental health diseases separated the causations and treatments from clinical protocols. By this, certain mental health diseases are incurable. Today, clinical facts have separated mental health disorders from the realm of spiritual causations with medical proofs that mental diseases comprise elements of genetic, psychological, environmental and sociological dispositions such as heart disease, drug abuse, anxiety, fever and other related medical issues. This happens that disease etiology, medical symptoms and physical examination define the type of mental disorder, diagnosis and treatment. This study aims at changing the traditional knowledge Igbo people have about mental disorders through creating wider clinical discussions on mental diseases. The study recommends that where there are cases of mental disorders, medical treatment, diagnosis and counselling (psychotherapy) should be considered appropriate.