Time Of Menstrual Cycle Research Articles

Food intake prior to a migraine attack--study of 2,313 spontaneous attacks.

SYNOPSISSandler, Youdim and Hannington noted an inability to oxidise tyramine and phenylethylamene in dietary and non dietary migraine sufferers‐l,883 female volunteers in Britain completed questionnaires detailing food intake during the 24 hours prior to spontaneous migraine attacks. Analysis of 2,313 attacks are reported. This revealed consumption of chocolate in 33%, cheese 40%, citrus fruits 21% and alcohol 23%. Fasting (5 hours day or 13 hours overnight) occurred in 67%. No dietary factors were isolated in 5%. Only 14% thought food caused their attacks and 2% blamed fasting. Sensitising factors analysed included age, time in menstrual cycle, pill taking and hysterectomy. The findings suggest that in double blind trials designed to elucidate dietary factors, one needs to consider the patient's intake during the 24 hours prior to the administration of the test capsule. A new approach to treatment is suggested with elimination of specific foods and avoidance of fasting.

MENSTRUAL PERIODICITY IN YOUNG P.E. STUDENTS

In a study involving women physical education students and non-physical education students, Rougier and Liquette (1962) could establish no physical difference in the characteristics of the menstrual periods of both groups. Agreement with this work was expressed by Mean and von Neiderhaeusern (1966), except that more abnormal menstruations were found in sporting women. Klaus and Schubert (1961) observed that the appearance of dysmenorrhea and anomalies of the menstrual period were present during hard physical training.In this study menstrual periodicity, blood flow time and the incidence of dysmenorrhea were investigated using women undergoing a three year course of physical education.Group A, Experimental Population — students undergoing a three year physical education course, n = 28.Group B, Control Population — students undergoing a three year non-physical education course, n = 15.Data collected over the three years of the investigation was subjected to detailed statistical analysis.No significance could be demonstrated between the two groups in respect of menstrual cycle time. However, group means and standard deviations of both groups after the first six months course work are interesting: [Table: see text]Significant differences were demonstrated between the groups in respect of blood flow time. (P ≥ 0.05)The incidence of dysmenorrhea was significantly different with Group A in respect of physical work load and significantly different between groups. (P ≥ 0.05)These findings agree with those of Rougier and Liquette (1962) in that no significant difference could be established between the two groups in respect of mean periodicity and with Mean and von Neiderhaeusern (1966) that abnormal menstrual periodicity was found in some sporting women.The incidence of dysmenorrhea was similar to that seen by Klaus and Schubert (1961) in that dysmenorrhea was present during hard physical training in some women.

Plasma steroid and luteinizing hormone levels during prostaglandin F 2 administration in luteal phase of menstrual cycle.

An intravenous infusion of prostaglandin F(2)alpha (12.5-250mug/min) was administered in four volunteers in the mid-late luteal phase and three in the early luteal phase of the menstrual cycle.Frequent measurement of plasma progesterone, oestrogens, and luteinizing hormone (LH) showed that administration of high doses depressed plasma progesterone levels in the late luteal phase and caused concomitant side effects. Levels of progesterone in the early luteal phase were unaffected. In both phases oestrogen and LH levels were little altered. In two subjects, hourly progesterone levels measured throughout the day at a similar time in a subsequent control menstrual cycle showed an appreciable variation in one but steady levels in the second. This variation may contribute to the magnitude of the fall in progesterone noted during the infusion of prostaglandins.

Trauma to the internal cervical os during dilatation for diagnostic curettage

Trauma to the internal cervical os during dilatation for diagnostic curettage is described. 154 hysterectomy specimens from patients who had had curettages were examined for evidence of trauma. 39% of the specimens had tears at the internal os over 2 mm in depth and 22% over 5 mm. There appeared to be no marked predisposing factors to the occurrence of these tears with respect to age parity underlying disease or time of menstrual cycle. No tears occurred when hyperplastic proliferative endometrium was present. It is suggested that the clinician be aware of the possibility of this injury occurring during a routine diagnostic dilatation and curettage. Adequate time should be allowed for a slower more gentle dilatation of the tissue when excessive resistance at the level of the internal os is encountered. Complete dilatation to the largest Hegar should be avoided.