Exercise In Men Research Articles

The Effect of Dietary Inorganic Nitrate Supplementation on Cardiac Function during Submaximal Exercise in Men with Heart Failure with Reduced Ejection Fraction (HFrEF): A Pilot Study.

Heart failure with reduced ejection fraction (HFrEF) is a common end point for patients with coronary artery disease and it is characterized by exercise intolerance due, in part, to a reduction in cardiac output. Nitric oxide (NO) plays a vital role in cardiac function and patients with HFrEF have been identified as having reduced vascular NO. This pilot study aimed to investigate if nitrate supplementation could improve cardiac measures during acute, submaximal exercise. Five male participants (61 ± 3 years) with HFrEF (EF 32 ± 2.2%) completed this pilot study. All participants supplemented with inorganic nitrate (beetroot juice) or a nitrate-depleted placebo for ~13 days prior to testing. Participants completed a three-stage submaximal exercise protocol on a recumbent cycle ergometer with simultaneous echocardiography for calculation of cardiac output (Q), stroke volume (SV), and total peripheral resistance (TPR). Heart rate and blood pressure were measured at rest and during each stage. Both plasma nitrate (mean = ~1028%, p = 0.004) and nitrite (mean = ~109%, p = 0.01) increased following supplementation. There were no differences between interventions at rest, but the percent change in SV and Q from rest to stage two and stage three of exercise was higher following nitrate supplementation (all p > 0.05, ES > 0.8). Both interventions showed decreases in TPR during exercise, but the percent reduction TPR in stages two and three was greater following nitrate supplementation (p = 0.09, ES = 0.98 and p = 0.14, ES = 0.82, respectively). There were clinically relevant increases in cardiac function during exercise following supplementation with nitrate. The findings from this pilot study warrant further investigation in larger clinical trials.

693-P: Oxidative–Antioxidant Balance after Maximum Intensity Exercise in Men with Type 1 Diabetes Treated with a Personal Insulin Pump vs. Healthy Control

One of the main reasons for the development of many diabetes complications is chronic hyperglycemia, which results in a number of mechanisms generating excessive production of reactive oxygen (ROS) and cause of avalanche growth of free radicals. Excessive production of ROS in the body or insufficient antioxidative barrier of the body can lead to intracellular damage. Intense physical exertion, may also violate the dynamic balance of prooxidants and antioxidants. The aim of the study was to verify the level of prooxidative-antioxidative balance in men with type 1 diabetes versus control group after maximum intensity exercise. The study included 30 men with type 1 diabetes treated with a personal insulin pumps aged 23.4 ± 5.1 with 11.4 ± 6.0 years of diabetes duration and mean HbA1c 7.2 ± 0.9%. 23 healthy men aged 24.7 ± 2.9 years were included in the control group. The march-running test on the treadmill to determine the maximal oxygen consumption (VO2max) was performed. Before and 60 minutes after the test total antioxidant status TAS (Immundiagnostik AG ImAnOx test, KC5200) and total prooxidative status TOS (test by Immundiagnostik AG PerOx, KC5100) in plasma were measured. The average level of VO2max (44.7 ± 5.7 vs. 56.0 ± 7.3) in the group of people with diabetes was significantly lower (p = 0.000) compared to the control group. Both before and after maximum exercise higher values of TOS levels (p = 0.000) was observed in patients with T1DM. The level of TAS before exercise was comparable in both groups, whereas after exercise it was significantly higher in the control group (p = 0.0000). In the diabetic group after maximum effort a decrease while in the control group a slight increase in TAS level was observed (p = 0.0174). The TOS/TAS [%] ratio was significantly higher both before and after the maximum effort in the T1DM group. Results of our study underline importance of increase oxidative stress in T1DM patients accompanying intense exercise. Disclosure B. Matejko: Other Relationship; Self; Dexcom, Inc., Roche Diabetes Care. &. Tota: None. M. Morawska: None. S. Mrozinska: Other Relationship; Self; Roche Diabetes Care. W. Pilch: None. T. Palka: None. B. Kiec-Wilk: None. M. Malecki: None. T. Klupa: Advisory Panel; Self; Abbott, AstraZeneca, Boehringer Ingelheim International GmbH, Eli Lilly and Company, Medtronic, Roche Diabetes Care, Sanofi. Employee; Spouse/Partner; Ascensia Diabetes Care. Funding Polish Diabetes Association (2017); University of Physical Education (185/BS/INB/2018)

Acute Psychological Effects of Resistance Exercise in Men With Symptoms of Muscle Dysmorphia: A Pilot Study.

SantaBarbara, NJ, Nosrat, S, Whitworth, JW, Ciccolo, JT. acute psychological effects of resistance exercise in men with symptoms of muscle dysmorphia: A pilot study. J Strength Cond Res 37(2): 277-283, 2023-This study tested the acute psychological effects of resistance exercise in men with symptoms of muscle dysmorphia. Twenty-one men completed 4 on-site sessions including a single session of moderate- (70% of 10 repetition maximum [RM]) and high- (100% of 10RM) intensity resistance exercise in a counter balanced order separated by at least 48 hours. State body image, perceived muscle size, exercise enjoyment, and ratings of perceived exertion (RPE) were assessed before, during, and after each session, and statistical significance was set a priori at p < 0.05. State body image significantly improve from pre to post during both sessions ( p < 0.01), with greater effect sizes seen for the high- ( d = 0.57) compared with the moderate- ( d = 0.39) intensity session. Perceived muscle size improved from pre to post during the high-intensity only ( p < 0.01, d = 0.66), and subjects enjoyed the high-intensity session significantly more than the moderate-intensity session ( p = 0.01), despite significantly higher RPE at each timepoint ( p < 0.01). Results contend with previous findings that show more positive psychological effects of moderate- compared with high-intensity resistance exercise. Education and client observation are essential to be aware of the potential for muscle dysmorphia. In instances where muscle dysmorphia is suspected, referral to qualified mental health professionals is recommended.

A Single Dose of The Mango Leaf Extract Zynamite® in Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women.

The mango leaf extract rich in mangiferin Zynamite® improves exercise performance when combined with luteolin or quercetin ingested at least 48 h prior to exercise. To determine whether a single dose of Zynamite® administered 1 h before exercise increases repeated-sprint performance, 20 men and 20 women who were physically active were randomly assigned to three treatments following a double-blind cross-over counterbalanced design. Treatment A, 140 mg of Zynamite®, 140 mg of quercetin, 147.7 mg of maltodextrin, and 420 mg of sunflower lecithin; Treatment B, 140 mg of Zynamite®, 140 mg of quercetin, and 2126 mg of maltodextrin and Treatment C, 2548 mg of maltodextrin (placebo). Subjects performed three Wingate tests interspaced by 4 min and a final 15 s sprint after ischemia. Treatments A and B improved peak power output during the first three Wingates by 2.8% and 3.8%, respectively (treatment x sprint interaction, p = 0.01). Vastus Lateralis oxygenation (NIRS) was reduced, indicating higher O2 extraction (treatment × sprint interaction, p = 0.01). Improved O2 extraction was observed in the sprints after ischemia (p = 0.008; placebo vs. mean of treatments A and B). Blood lactate concentration was 5.9% lower after the ingestion of Zynamite® with quercetin in men (treatment by sex interaction, p = 0.049). There was a higher Vastus Lateralis O2 extraction during 60 s ischemia with polyphenols (treatment effect, p = 0.03), due to the greater muscle VO2 in men (p = 0.001). In conclusion, a single dose of Zynamite® combined with quercetin one hour before exercise improves repeated-sprint performance and muscle O2 extraction and mitochondrial O2. consumption during ischemia. No advantage was obtained from the addition of phospholipids.

Pre-surgical Exercise In Men With Prostate Cancer Undergoing Prostatectomy

Pre-surgical Exercise In Men With Prostate Cancer Undergoing Prostatectomy

A Longitudinal Examination of the Social-Ecological Correlates of Exercise in Men and Women Following Cardiac Rehabilitation.

Cardiac patients who engage in ≥150 min of moderate- to vigorous-intensity physical activity (MVPA)/week have lower mortality, yet MVPA declines even following cardiac rehabilitation (CR), and is lower in women. A randomized trial of nine socioecological theory-based exercise facilitation contacts over 50 weeks versus usual care (1:1 parallel arms) was undertaken (NCT01658683). The tertiary objective, as presented in this paper, was to test whether the intervention impacted socioecological elements, and in turn their association with MVPA. The 449 participants wore an accelerometer and completed questionnaires post-CR, and 26, 52 and 78 weeks later. At 52 weeks, exercise task self-efficacy was significantly greater in the intervention arm (p = 0.01), but no other differences were observed except more encouragement from other cardiac patients at 26 weeks (favoring controls). Among women adherent to the intervention, the group in whom the intervention was proven effective, physical activity (PA) intentions at 26 weeks were significantly greater in the intervention arm (p = 0.04), with no other differences. There were some differences in socioecological elements associated with MVPA by arm. There were also some differences by sex, with MVPA more often associated with exercise benefits/barriers in men, versus with working and the physical environment in women.

Amount and Socio-Ecological Correlates of Exercise in Men and Women at Cardiac Rehabilitation Completion.

The aim of the study was to describe (1) the amount of physical activity (PA) in cardiac rehabilitation (CR) graduates by sex, and (2) the correlates of their PA. Secondary analysis of baseline data from a randomized trial was undertaken. Graduates were recruited from three CR programs. Participants completed a questionnaire, which assessed constructs from the socio-ecological model (i.e., individual-level, social- and physical-environmental levels). Physical activity was measured objectively using an ActiGraph GT3X accelerometer. Multilevel modeling was performed. Two hundred fifty-five patients consented, of which 200 (78.4%) completed the survey and provided valid accelerometer data. Participants self-reported engaging in a mean ± standard deviation of 184.51 ± 129.10 min of moderate-to-vigorous-intensity PA (MVPA) per week (with men engaging in more than women, P < 0.05). Accelerometer data revealed participants engaged in 169.65 ± 136.49 mins of MVPA per week, with 43 (25.1%) meeting recommendations. In the mixed models, the socio-ecological correlate significantly related to greater self-reported MVPA was self-regulation (P = 0.01); the correlate of accelerometer-derived MVPA was neighborhood aesthetics (P = 0.02). Approximately one-quarter of CR program completers are achieving MVPA recommendations, although two-thirds perceive they are. The CR programs should exploit accelerometry and promote self-regulation skills, namely, self-monitoring, goal-setting, positive reinforcement, time management, and relapse prevention. Patients should be encouraged to exercise in pleasing locations.

Benefits of Immediate Versus Delayed Exercise in Men Initiating ADT for Prostate Cancer

PURPOSE: To examine whether it was more efficacious to commence exercise at the onset of ADT rather than later in treatment to counter declines in strength and physical function. METHODS: One hundred and four men with PCa (68.3±7.0 years, 29.7±5.2 % fat, Gleason score 7.6±0.9) initiating ADT were randomised to immediate exercise (EX, n=54) or delayed exercise (DEL, n=50) for 12 months. EX comprised 6 months of supervised resistance/aerobic/impact exercise initiated at onset of ADT with 6-month follow-up. DEL comprised 6 months usual care followed by 6 months of resistance/aerobic/impact exercise. Muscle strength (chest press, leg press, seated row) and physical performance (6-m usual and fast walk, 6-m backwards walk, 400-m walk, stair climb, repeated chair rise) were assessed at baseline, 6 and 12 months. Data were analysed by ANCOVA using an intention-to-treat approach. RESULTS: There was a significant difference for all strength measures at 6 months favouring EX (p<0.001), with net differences in leg press, seated row and chest press strength of 19.9 kg (95% CI, 12.3 to 27.5 kg), 5.6 kg (3.8 to 7.4 kg), and 4.3kg (2.7 to 5.8 kg), respectively. From 6-12 months DEL increased in all strength measures (p<0.001) such that there were no differences between groups at 12 months. Similarly, physical performance improved (p<0.001) in EX compared to DEL at 6 months for the 400-m walk (-9.7 s, 95% CI -14.8 to -4.6 s), stair climb (-0.4 s, -0.6 to -0.2 s) and chair rise (-1.0 s, -1.4 to -0.7 s), with no differences between groups by 12 months. CONCLUSION: Exercise either at the onset or after 6 months ADT preserves/enhances muscle strength and physical function. However, to avoid any initial treatment-related adverse effects on strength and function, exercise should be prescribed and commenced at the onset of ADT.

Predicting Energy Expenditure of an Acute Bout of Resistance Exercise in Men and Women

Predicting Energy Expenditure of an Acute Bout of Resistance Exercise in Men and Women

Predictors of Sexual Intercourse Frequency Among Couples Trying to Conceive

BackgroundLittle is known about the predictors of sexual intercourse frequency (SIF) among couples trying to conceive despite the well-established link between SIF and fecundity. AimTo evaluate men's and women's demographic, occupational, and lifestyle predictors of SIF among couples. Methods469 Couples without a history of infertility participating in the Longitudinal Investigation of Fertility and the Environment Study (2005–2009) were followed up for ≤1 year while trying to conceive. At enrollment, both partners were interviewed about demographic, occupational, lifestyle, and psychological characteristics using standardized questionnaires. Multivariable generalized linear mixed models with Poisson distribution were used to estimate the adjusted percent difference in SIF across exposure categories. OutcomesSIF was recorded in daily journals and summarized as average SIF/mo. ResultsThe median (interquartile range) SIF during follow-up was 6 (4–9) acts/mo. For every year increase in age for women and men, SIF decreased by –0.8% (95% CI –2.5 to 1.0%) and –1.7% (95% CI –3.1 to –0.3%). Women with high school education or less and those of non-white race had 34.4% and 16.0% higher SIF, respectively. A similar trend was seen for men's education and race. Only couples where both partners (but not just 1 partner) worked rotating shifts had –39.1% (95% CI –61.0 to –5.0%) lower SIF compared to couples where neither partner worked rotating shifts. Men's (but not women's) exercise was associated with 13.2% (95% CI 1.7–26.0%) higher SIF. Diagnosis of a mood or anxiety disorder in men (but not women) was associated with a 26.0% (95% CI –42.7 to –4.4%) lower SIF. Household income, smoking status, body mass index, night work, alcohol intake, and psychosocial stress were not associated with SIF. Clinical TranslationEven among couples trying to conceive, there was substantial variation in SIF. Both partners' age, education, race, and rotating shift work as well as men's exercise and mental health play an important role in determining SIF. ConclusionsAs this was a secondary analysis of an existing study, we lacked information on many pertinent psychological and relationship quality variables and the hormonal status of participants, which could have affected SIF. The unique population-based couple design, however, captured both partners' demographics, occupational characteristics, and lifestyle behaviors in advance of their daily, prospective reporting of SIF, which was a major strength. Important predictors of SIF among couples attempting to conceive include men's exercise and mental health and both partners' age, education, race, and rotating shift work.Gaskins AJ, Sundaram R, Buck Louis GM, et al. Predictors of Sexual Intercourse Frequency Among Couples Trying to Conceive. J Sex Med 2018;15:519–528.

Intraindividual Variability and Validity in Smart Apparel Muscle Activity Measurements During Exercise in Men

Intraindividual Variability and Validity in Smart Apparel Muscle Activity Measurements During Exercise in Men

Glycemic and Metabolic Effects of Two Long Bouts of Moderate-Intensity Exercise in Men with Normal Glucose Tolerance or Type 2 Diabetes.

The glycemic and insulinemic responses following 30-60 min of exercise have been extensively studied, and a dose-response has been proposed between exercise duration, or volume, and improvements in glucose tolerance or insulin sensitivity. However, few studies have examined the effects of longer bouts of exercise in type 2 diabetes (T2D). Longer bouts may have a greater potential to affect glucagon, interleukin-6 (IL-6) and incretin hormones [i.e., glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP)]. To examine the effect of two bouts of long-duration, moderate-intensity exercise on incretins, glucagon, and IL-6 responses before and after exercise, as well as in response to an oral glucose tolerance test (OGTT) conducted the following day. Twelve men, six with and six without T2D, participated in two separate conditions (i.e., exercise vs. rest) according to a randomized crossover design. On day 1, participants either rested or performed two 90 min bouts of treadmill exercise (separated by 3.5 h) at 80% of their ventilatory threshold. All participants received standardized meals on day 1. On day 2 of each condition, glucose and hormonal responses were measured during a 4-h OGTT. On day 1, exercise increased IL-6 at the end of the first bout of exercise (exercise by time interaction p = 0.03) and GIP overall (main effect of exercise p = 0.004). Glucose was reduced to a greater extent in T2D following exercise (exercise by T2D interaction p = 0.03). On day 2, GIP and active GLP-1 were increased in the fasting state (p = 0.05 and p = 0.03, respectively), while plasma insulin and glucagon concentrations were reduced during the OGTT (p = 0.01 and p = 0.02, respectively) in the exercise compared to the rest condition for both healthy controls and T2D. Postprandial glucose was elevated in T2D compared to healthy control (p < 0.05) but was not affected by exercise. Long-duration, moderate-intensity aerobic exercise can increase IL-6. On the day following exercise, fasting incretins remained increased but postprandial insulin and glucagon were decreased without affecting postprandial glucose. This long duration of exercise may not be appropriate for some people, and further research should investigate why next day glucose tolerance was unchanged.

High-intensity Exercise in Men with Type 1 Diabetes and Mode of Insulin Therapy.

The purpose of this study was to evaluate the impact of high intensity exercise on glucose levels and risk of metabolic decompensation in males with type 1 diabetes (T1D), depending on the method of insulin administration. The study comprised 29 males (aged 25.3±5.1 years; duration of diabetes 10.3±3.2 years) treated with continuous subcutaneous insulin infusion (CSII) or multiple daily insulin injections (MDI). Treadmill exercise test was performed twice in each patient until subjective exhaustion as maximum according to the Borg scale. All the patients achieved ≥85% of the maximal heart rate. Distance during the test was 4 500±1 400 m and 4 473±1 559 m in the MDI and CSII groups, respectively, which was achieved in 31±8 min. During the test and in the 6 h after, no clinically significant episodes of hypoglycemia occurred. Mean glucose levels did not exceed 10 mmol/L in most patients. The risk of the composite endpoint (hypoglycemia<3.8 mmol/L, hyperglycemia≥16.6 mmol/L, ketones≥0.6 mmol/L, and lactate>2.2 mmol/L) was higher in patients treated with MDI than CSII (OR3.75, 95%CI:1.22-11.52, p=0.02). In conclusion, planned high intensity physical effort in men with well-controlled T1D is metabolically safe. CSII shows greater metabolic advantage over MDI during and after high intensity exercise in men with T1D.

Circulating MicroRNA Are Predictive of Aging and Acute Adaptive Response to Resistance Exercise in Men.

Circulating microRNA (c-miRNA) have the potential to function as novel noninvasive markers of the underlying physiological state of skeletal muscle. This investigation sought to determine the influence of aging on c-miRNA expression at rest and following resistance exercise in male volunteers (Young: n = 9; Older: n = 9). Primary findings were that fasting c-miRNA expression profiles were significantly predictive of aging, with miR-19b-3p, miR-206, and miR-486 distinguishing between age groups. Following resistance exercise, principal component analysis revealed a divergent response in expression of 10 c-miRNA, where expression profiles were upregulated in younger and downregulated in older participants. Using Ingenuity Pathway Analysis to test c-miRNA-to-mRNA interactions in skeletal muscle, it was found that response of c-miRNA to exercise was indicative of an anabolic response in younger but not older participants. These findings were corroborated with a positive association observed with the phosphorylation status of p-AktSer473 and p-S6K1Thr389 and expression of miR-19a-3p, miR-19b-3p, miR-20a-5p, miR-26b-5p, miR-143-3p, and miR-195-5p. These important findings provide compelling evidence that dysregulation of c-miRNA expression with aging may not only serve as a predictive marker, but also reflect underlying molecular mechanisms resulting in age-associated declines in skeletal muscle mass, increased fat mass, and "anabolic resistance."

Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing Prostatectomy.

Background: Prostatectomy is associated with short- and long-term morbidity, which includes attenuation of muscle function and deterioration of lean body mass. Physical function is a known predictor of morbidity and mortality, with initial evidence indicating that presurgical exercise is associated with fewer postsurgical complications and shorter hospitalization. The aim was to determine the feasibility of a supervised presurgical exercise program for prostate cancer (PCa) patients scheduled for prostatectomy. Methods: Ten men (68+6.4 years old) with localized PCa undertook a 6-week resistance and aerobic exercise program prior surgery. Training was undertaken twice weekly and patients were assessed at baseline, presurgery, and 6 weeks postsurgery. Outcome measures included muscle and physical performance, body composition, urinary incontinence and questionnaire. Results: Muscle strength increased by 7.5% to 24.3% (P < .05) from baseline to presurgery but decreased to pretraining levels postsurgery, except for knee extensor strength (P = .247). There were significant improvements (P < .05) in the 6-m fast walk (9.3%), 400-m walk (7.4%), and chair rise (12.3%) at presurgery. Following surgery, improvements in physical performance were maintained. There was no change in lean or fat mass prior to surgery, but lean mass declined by 2.7 kg (P = .014) following surgery. There were no adverse effects from the exercise program. Conclusions: Exercise undertaken prior to prostatectomy improved muscle and physical performance, with functional benefits maintained 6 weeks postsurgery. Presurgical exercise for PCa patients has the potential to facilitate recovery by improving physical reserve capacity, especially in men with poor muscle nd physical performance.

Effects Of Inspiratory Muscle Training On Inspiratory And Locomotor Muscle Hemodynamics During Exercise In Men

High levels of respiratory muscle work may elicit a redistribution of blood flow from the locomotor to the respiratory muscles during exercise. It is unknown if specific inspiratory muscle training (IMT) can attenuate this response during high-intensity, whole-body exercise. PURPOSE: To examine the hemodynamic responses of multiple inspiratory muscles and the vastus lateralis (VL) during incremental cycling before and after 5 weeks of IMT. METHODS: After a comprehensive familiarization visit, 25 recreationally active healthy men (mean±SD; age=24±4; maximal aerobic power (V[Combining Dot Above]O2max)=52±10 ml·kg-1·min-1) completed two maximal incremental cycle exercise tests (25W/2min steps) separated by 5 weeks of pressure threshold IMT or sham-control training (SC). The IMT group (n=12) performed 30 inspiratory efforts twice daily against a minimum resistance of 50% of maximum inspiratory pressure (MIP), adjusted weekly. The SC (n=13) group performed a daily bout of 60 inspiratory efforts against 10% MIP using the same device with no weekly adjustments. During the incremental cycle tests, participants were instrumented with NIRS optodes on the sternocleidomastoid (SCM), parasternal intercostals (PIC), 7th intercostal space (7IC), and VL to measure changes in oxygenated, deoxygenated, and total hemoglobin (tHb) concentrations. RESULTS: The IMT and SC groups were well matched for age, height, mass, and V[Combining Dot Above]O2max. There was a significant increase in MIP in the IMT group (mean±SD, 135±44 vs. 159±35 cmH2O, p<0.05) but not in the SC group (134±39 vs. 134±44 cmH2O, p>0.05). No differences were detected when comparing pre vs. post-IMT for any NIRS derived variables at relative percentages of maximal work rate (20, 40, 60, 80,100%) for any muscle in both the IMT and SC groups. The tHb (muscle blood volume) at the highest equivalent absolute work rate achieved by an individual on each test in the IMT group (pre vs. post-IMT) was 3±15 vs. 1±25, 1±9 vs. 2±11, -6±12 vs. -6±12, and 12±10 vs. 11±9[INCREMENT]μM whereas the SC group was 2±11 vs. 3±6, 1±9 vs. 4±8, -6±6 vs. -6±8, and 12±8 vs. 9±10[INCREMENT]μM in the SCM, PIC, 7IC, and VL, respectively (all p>0.05). CONCLUSION: Five weeks of pressure-threshold IMT had no effect on respiratory or locomotor muscle hemodynamics during incremental cycle exercise in healthy recreationally active men. Supported NSERC

Changes in Non-Enzymatic Antioxidants in the Blood Following Anaerobic Exercise in Men and Women.

PurposeThe aim of this study was to compare changes in total oxidative status (TOS), total antioxidative capacity (TAC) and the concentration of VitA, VitE, VitC, uric acid (UA), reduced (GSH) and oxidized glutathione (GSSG) in blood within 24 hours following anaerobic exercise (AnEx) among men and women.Methods10 women and 10 men performed a 20-second bicycle sprint (AnEx). Concentrations of oxidative stress indicators were measured before AnEx and 3, 15 and 30 minutes and 1 hour afterwards. UA, GSH and GSSH were also measured 24 hours after AnEx. Lactate and H+ concentrations were measured before and 3 minutes after AnEx.ResultsThe increase in lactate and H+ concentrations following AnEx was similar in both sexes. Changes in the concentrations of all oxidative stress indicators were significant and did not differ between men and women. In both sexes, TOS, TAC, TOS/TAC and VitA and VitE concentrations were the highest 3 minutes, VitC concentration was the highest 30 minutes, and UA concentration was the highest 1 hour after AnEx. GSH concentration was significantly lower than the initial concentration from 15 minutes to 24 hour after AnEx. GSSG concentration was significantly higher, while the GSH/GSSG ratio was significantly lower than the initial values 1 hour and 24 hour after AnEx.ConclusionsWith similar changes in lactate and H+ concentrations, AnEx induces the same changes in TAC, TOS, TOS/TAC and non-enzymatic antioxidants of low molecular weight in men and women. Oxidative stress lasted at least 24 hours after AnEx.

Discussion of Relationship between Hematuria and Ultrasonic Renal Calculi in Young Man After Exercise

&lt;strong&gt;Objective: &lt;/strong&gt;To discuss the relationship between hematuria and ultrasonic renal calculi in young man after exercise. &lt;strong&gt;Method:&lt;/strong&gt; In the medical observation, 48 cases of young male patients with hematuria after exercise in our hospital from January 2011 to December 2012 were selected as the observation objects, the subjects were transient hematuria, and 92 patients without hematuria were selected as the contrast, all patients underwent ultrasound examination, the detection rate of renal calculi and the ultrasonic manifestation were retrospectively analyzed. &lt;strong&gt;Results: &lt;/strong&gt;The incidence of renal calculi of the young and middle-aged male patients with hematuria after exercise is statistically different in different parts and different age (&lt;em&gt;p&lt;/em&gt; &amp;lt; 0.05), and the incidence rate of renal calculi in patients with hematuria after exercise and patients without hematuria was significantly different (&lt;em&gt;p&lt;/em&gt; &amp;lt; 0.05), as shown in Table 1, Table 2. There was no obvious linear relationship between the degree of hematuria and the incidence of renal calculi after young men's exercise, as shown in Table 3. &lt;strong&gt;Conclusion: &lt;/strong&gt;From this clinical research results we can know that renal calculi is the main cause of hematuria after exercise for the young man, and the clinical examination and diagnosis of renal calculi with ultrasonography has higher clinical detection rate, therefore the clinical application value is higher.

Spousal Influence on Physical Activity in Middle-Aged and Older Adults: The ARIC Study.

Low physical activity levels are a public health concern. Few studies have assessed the concordance of physical activity change among spouses. We studied this concordance during a 6-year period (baseline: 1987-1989; follow-up: 1993-1995) in 3,261 spousal pairs from the US-based Atherosclerosis Risk in Communities (ARIC) Study. Linear regression was used to examine the association between change in individuals' sport/exercise and leisure physical activity indices (ranging from 1 (low) to 5 (high)) and change in his or her spouse's indices. The association between individual and spousal changes in meeting physical activity recommendations was assessed with logistic regression. Individual changes in the sport/exercise and leisure indices were positively associated with spousal changes. For every standard deviation increase in their wives' sport/exercise index, men's exercise index increased by 0.09 (95% confidence interval: 0.05, 0.12) standard deviation; for every standard deviation increase in their wives' leisure index, men's leisure index increased by 0.08 standard deviation. Results were similar for women. Individuals had higher odds of meeting physical activity recommendations if their spouse met recommendations at both visits or just follow-up. In conclusion, changes in an individual's physical activity are positively associated with changes in his or her spouse's physical activity. Physical activity promotion efforts should consider targeting couples.

Oxygen On-kinetics During Progressive Exercise In Men And Women

PURPOSE: To examine the relationship of fitness and adiposity on pulmonary oxygen uptake kinetics (VO2 on-kinetics) in men and women who completed a progressive exercise treadmill test. METHODS: Thirty-nine recreational runners (Men: n=10, 47.5±7.5 yrs; Women: n=29, 46.4±8.1 yrs) volunteered to participate. The association of VO2 on-kinetics and peak oxygen consumption per fat free mass (peakVO2FFM), body mass index (BMI), and body fatness (%BF) was determined using multiple linear regression modeling. RESULTS: No significant differences were observed between genders in peakVO2FFM (p=0.986) and VO2 on-kinetics (p=0.407). Within men, there was a significant independent association between VO2 on-kinetics and peakVO2FFM (beta= 1.376, p=0.001), BMI (beta=2.088, p=0.004), and %BF (beta= -1.978, p=0.006). However, in women, only peakVO2FFM (beta=0.395, p=0.028) uniquely contributed to VO2 on-kinetics. CONCLUSIONS: In men, both BMI and %BF independently impact VO2 on-kinetic variance during a progressive exercise bout. Although peakVO2FFM independently explains VO2 on-kinetic variance in both genders, it appears to provide a larger contribution in men (76%) compared to that observed in women (13%).