Memory Issues Research Articles

Human Herpesvirus-6B Infection and Alterations of Gut Microbiome in Patients with Fibromyalgia: A Pilot Study

Fibromyalgia (FM) is a chronic disorder characterized by widespread musculoskeletal pain often accompanied by fatigue, sleep disturbances, memory issues, and mood disorders. The exact cause of FM remains unknown, and diagnosis is typically based on a history of persistent widespread pain, as there are no objective biomarkers usable in diagnosis of this disorder available. The aim of this study was to identify measurable indicators specific to FM with potential as biomarkers. This study included 17 individuals diagnosed with FM and 24 apparently healthy persons. Using real-time polymerase chain reaction (qPCR), we detected the presence of human herpesvirus (HHV)-6A and B genomic sequences in DNA isolated from peripheral blood mononuclear cells (PBMCs) and buccal swabs. HHV-6-specific IgG and IgM class antibodies, along with proinflammatory cytokine levels, were measured using enzyme-linked immunosorbent assay (ELISA) and bead-based multiplex assays. Additionally, the gut microbiome was analyzed through next-generation sequencing. HHV-6B was more frequently detected in the PBMCs of FM patients. FM patients with a body mass index (BMI) of 30 or higher exhibited elevated cytokine levels compared to the control group with the same BMI range. Gut microbiome analysis revealed significant differences in both α-diversity and β-diversity between the FM and control groups, indicating a shift in species abundance in the FM group.

6668 Myxedema Coma and Takotsubo Cardiomyopathy

Abstract Disclosure: A.M. Skariah: None. S. Jain: None. Background: Takotsubo cardiomyopathy (TCM) also know as broken heart syndrome is a transient decrease in systolic cardiac function in the absence of obstructive CAD. TCM is likely related to hyperadrenergic conditions leading to increased cardiac sensitivity to catecholamine surge leading to cardiomyopathy. TCM is more associated with hyperthyroidism. Case presentation: Patient is an 84-year-old female with PMH of celiac disease,hypertension,prediabetes, and atrial fibrillation s/p cardioversion, on amiodarone. She was brought to the ER after having an unwitnessed fall. She was hypotensive 76/56 mm of Hg, hypothermic 35.5 degree C, HR 90 beats/min; labs significant for hyponatremia, macrocytic anemia, TSH 65.47uIU/ml, FT4 <0.4 ng/dl and mild QTC prolongation of 469ms. Family mentioned history of constipation, progressive weakness, poor oral intake, memory problems and cold sensitivity for a couple of months. Started on 1 pressor, 3 units of PRBC and 2 liters of IVF; BP improved; labs and history suggestive of myxedema coma with myxedema coma Popoveniuc score 85 suggestive of high suspicion for myxedema coma.She had TSH 50.39 uIU/ml and FT4 of 0.4 ng/dl for her memory issues workup 2 months prior to presentation but was not started on medication. Upon admission, started stress dose steroids followed by IV levothyroxine 100 mcg. Not started on LT3 given her old age and atrial fibrillation history. Received additional dose of LT4 100 mcg within few hours. TFT improved with TSH 35 uIU/ml and FT4 1 ng/dl after 2 doses. Later same day, shock worsened, and patient was on 3 pressors along with stress dose of steroids. Cardiology was consulted; recommended an Echocardiogram.Echo was done on day 2; EF 55-60 % with severe hypokinesis of apical myocardium consistent with TCM. Normal echocardiogram studies 4 months ago.Started on weight-based regimen of LT4 75 mcg IV on day 3 and switched to 100 mcg oral when patient tolerated pills.Patient was down to 2 pressors on day 3 and gradually off pressors by day 6. Repeat TFT -showed improvement TSH 12 uIU/ml and FT4 0.7 ng/dl—day 5. Eventually her mentation improved and was discharged on oral LT4. Conclusion: TCM is rare complication of treatment of myxedema coma. Our patient developed shock requiring 1 pressor which unexpectedly worsened to 3 pressors requirement after initial LT4 treatment. High doses of LT4 and LT3 which is part of myxedema coma treatment sensitizes myocardial tissue to catecholamines by increasing expression of beta adrenoreceptors in cardiac myocytes with subsequent ionotropic and chronotropic effects. This may contribute to cardiac stunning and TCM. It’s beneficial to evaluate patients with myxedema coma who develop worsening cardiac status after initiation of high dose of thyroid hormone replacement for TCM. Presentation: 6/2/2024

Preface: special issue in memory of the 90th birthday of Prof. Quan Yuan

Preface: special issue in memory of the 90th birthday of Prof. Quan Yuan

Blueprint Persona and ICT Interventions: Addressing Unmet Needs in Burning Mouth Syndrome Care

ObjectivesThis study aimed to create a Blueprint Persona for Burning Mouth Syndrome (BMS) patients, focusing on unmet needs that digital solutions can address. MethodsAn interdisciplinary focus group formulated the BMS Blueprint Persona by discussing clinical data and survey results regarding education, informatics skills, and perceived unmet needs, collected from 500 BMS patients between 2022 and 2023. ResultsThe BMS Blueprint Persona, named Anna, represents a typical BMS patient profile: a young-old woman with limited computer skills who experiences anxiety, depression, and insomnia, has memory issues leading to medication adherence challenges, is obese due to overeating, and spends much time watching TV at home. Anna's primary concern is receiving inadequate treatment and not achieving disease remission. She also feels misunderstood and lacks family support. This persona reveals several areas where Information and Communication Technology (ICT) interventions, like telemedicine, anxiety and insomnia treatment, drug adherence improvement, and nutritional and lifestyle guidance, could be beneficial. The focus group also outlined the essential features for a prospective mHealth app to meet BMS patients' diverse needs. ConclusionThe development of the BMS Blueprint Persona successfully identified patient characteristics and unmet needs, offering valuable insights for creating personalized diagnostic-therapeutic pathways and digital health solutions for BMS.

Functional brain alterations in COVID-19 patients using resting-state fMRI: a systematic review.

This study systematically reviews the available evidence on resting-state functional magnetic resonance imaging (rs-fMRI) related to neurological symptoms and cognitive declines in COVID-19 patients. We followed PRISMA guidelines and looked up the PubMed, and Scopus databases for articles search on COVID-19 patients with neurological impairments, and functional connectivity alteration using rs-fMRI technique. Articles published between January 1, 2020, and May 31, 2024, are included in this study. The Quality Assessment Tool for Observational Prospective and Cross-Sectional Studies from the National Heart, Lung, and Blood Institute (NHLBI) was used to assess the quality of papers. A total of 15 articles met the inclusion criteria. The result reveals that the most prevalent neurological impairment associated with COVID-19 was cognitive decline, encompassing issues in attention, memory, processing speed, executive functions, language, and visuospatial ability. The brain connectivity results reveal that two brain areas were functionally altered; the prefrontal cortex and parahippocampus. The functional connectivity mainly increased in the frontal, temporal, and anterior piriform cortex, and reduced in the cerebellum, superior orbitofrontal cortex, and middle temporal gyrus, which also correlated with cognitive decline. The findings of neurological symptoms indicate one study reported a Disorder of Consciousness (DoC), and four studies reported COVID-19 patients with olfactory dysfunction. The present study concludes that COVID-19 can alter brain functional connectivity and offers significant insight into how COVID-19 affects the neuronal foundation of cognitive decline and other neurological impairments.

Frail Patients Referred to a Community Specialist Team- What Were Their Frailty Scores?

Abstract Background Frailty is synonymous with older patients, where multiple body systems slowly lose their reserves and lead patients to become more vulnerable. When developing the inclusion criteria for our integrated care programme for older persons (ICPOP), the limited resources and large geographical area played a role. In order to maximize the outcomes for patients we targeted those with a Rockwood Clinical Frailty Score (CFS) between 4 and 6. We perceived that these patients would benefit from multidisciplinary intervention. Methods All patients referred to ICPOP were reviewed from November 2022 to April 2024. Our electronic patient database records information on ICPOP patients. Using this database we searched for the word “frailty” in the reason for referral field. We also correlated this with any patients who had a CFS recorded. The level of frailty in older patients with the scores ranging from 1 (very fit) to 9 (terminally ill) was recorded. Results 182 patients were found during the database search. 55 patients were referred for frailty alone, 64 patients were referred for frailty with balance/mobility issues, 47 patients were referred for frailty with falls, 16 patients were referred for frailty with memory issues. CFS were available for 132/182(73%) patients. 119/132(90 %) patients with a CFS score were classified as scoring between 4 and 6 on the Rockwood scale. 3/132(2%) scored 2, 6/132(5%) scored 3 and 4/132(3%) scored 7 on the CFS. Conclusion The national ICPOP framework prioritise improving care of frail older patients. A measure of a persons’ frailty level is subjective and dependent on clinical judgement along with a good understanding of the term “frailty”. Overall, our findings highlight that the referrers to our service have a good knowledge of frailty as a term. Our ICPOP hub is also effectively targeting the appropriate cohort of patients as per our inclusion criteria.

“Aiming at a moving target”—The daily life experiences of adolescents and young adults with a low-grade glioma

Abstract Background Low-grade gliomas (LGG) are among the most frequently occurring tumors in adolescent and young adult (AYA) patients (aged 18–39 years old at primary diagnosis). These tumors have a variable prognosis, presenting challenges for patients in shaping their future. This study aimed to identify the age-specific experiences and needs of AYA patients with LGG in their daily lives. Methods In-depth interviews were conducted with AYA patients diagnosed with LGG. Thematic analysis was performed to derive the age-specific codes, looking for overarching themes and sub-themes. Results Sixteen patients participated in this study. The cognitive symptoms of the disease (including difficulty concentrating, memory issues, and speech problems) are invisible to others but caused significant disruptions in many domains that were particularly important to AYA patients (eg, employment, family life, and autonomy). Additionally, the uncertainty regarding their life expectancy led to difficulties in making decisions about the future. They also perceived a lack of control over their future and the time they had left. Conclusions LGG have a significant impact on AYA patients. However, this impact is not fully understood by others close to them. The results highlight the importance of providing these patients with appropriate peer support, interventions tailored to both their disease and life phase, utilizing a multidisciplinary approach, and maintaining a focus on long-term support for these patients. It is crucial to provide AYA care for these patients within the neurology department, as LGG involve both tumor- and age-specific problems.

A Novel Perturbation Consistency Framework in Semi-Supervised Medical Image Segmentation

Semi-supervised medical image segmentation models often face challenges such as empirical mismatch and data imbalance. Traditional methods, like the two-stream perturbation model, tend to over-rely on strong perturbation, leaving weak perturbation and labeled images underutilized. To overcome these challenges, we propose an innovative hybrid copy-paste (HCP) method within the strong perturbation branch, encouraging unlabeled images to learn more comprehensive semantic information from labeled images and narrowing the empirical distribution gap. Additionally, we integrate contrastive learning into the weak perturbation branch, where contrastive learning samples are selected through semantic grouping contrastive sampling (SGCS) to address memory and variance issues. This sampling strategy ensures more effective use of weak perturbation data. This approach is particularly advantageous for pixel segmentation tasks with severely limited labels. Finally, our approach is validated on the public ACDC (Automated Cardiac Diagnosis Challenge) dataset, achieving a 90.6% DICE score, with just 7% labeled data. These results demonstrate the effectiveness of our method in improving segmentation performance with limited labeled data.

B - 84 Memory and Attention Predict Narcissistic Personality Characteristics

Abstract Objective Narcissistic Personality Disorder (NPD) entails grandiosity, lack of empathy, and a need for admiration. Research suggests a distinct cognitive profile linked to narcissistic characteristics, including facial recognition and memory issues. Our study examined memory and attention predictors of NPD characteristics in a non-clinical sample, filling a research gap. Method Young adult (M = 19.9, SD = 3.4) university students (N = 109) were participants. They identified primarily as women (52.3%) or men (47.7%) and White (65.1%) or African American (29.4%). Measures included Test of Everyday Attention (Robertson et al., 1996) and the Wechsler Memory Scale – IV (Wechsler, 2009) to assess memory and attention functioning. The Millon Clinical Multiaxial Inventory – III (Millon et al., 2006) was used to measure narcissistic personality disorder characteristics. The Test of Nonverbal Intelligence-4 (Brown et al., 2010) was used to estimate IQ. Results Regression analysis revealed significant associations between memory/attention facets and NPD characteristics, F(7, 101) = 2.18, p = 0.04, adj. R2 = 0.07, 95% CI [0, 0.12]. Divided attention (β = −0.236, p = 0.02) and associative memory (β = −0.222, p = 0.04) were significant predictors. After controlling for IQ, associative memory remained significant (β = −0.257, p = 0.02), while divided attention did not (β = −0.102, p = 0.32). Verbal list learning emerged as a risk factor (β = 0.258, p = 0.04). Conclusions Our findings align with prior research, indicating cognitive correlates of NPD, particularly poorer associative memory and better verbal list learning. These results suggest a unique cognitive profile for NPD, characterized by high verbal list learning and poor associative memory. Understanding these cognitive underpinnings sheds light on the complexity of NPD and may inform interventions.

Enhancing Data Integrity with Efficient Retention-Refilling Programming Schemes

The retention error has become one of the most challenging reliability issues of flash memory due to the shrinking of the technology nodes. To enhance data integrity by resolving the retention error issues for 3D MLC flash memory devices (e.g., SSDs and SD cards), many excellent works that exploited in-place reprogramming and data refreshing concepts have been proposed in recent years. However, these approaches could result in additional issues, such as programming disturbance and performance overhead (e.g., unavoidable data refreshing and a larger amount of program and verify shots). This work is motivated by the need to explore a low-cost solution to resolve retention error issues without incurring negative impacts caused by conventional refresh-based and in-place reprogramming approaches. As a result, this work exploits the characteristics of the cell's V t distribution and proposes the novel concept of "retention-refilling" to enhance data integrity. With such an idea, a retention-refillable programming scheme is proposed to improve flash reliability and mitigate performance overheads by trading data refreshing with retention-refilling. The capability of the proposed scheme is evaluated by a series of experiments, for which we have very encouraging results.

Psychotherapy Supervision: An Invitational, Clarifying, Educational, Empowering, and Transparent (ICEE-T) Written Agreement.

The authors make the case for using a written instead of a spoken supervision agreement at supervision's outset in order to provide clarity and education about supervision, supply an accessible document that supervisees can readily reference, sidestep memory issues that negatively affect the supervision process, and enable dyadic collaboration that sets an immediate positive tone for supervision. The invitational, clarifying, educational, empowering, and transparent (ICEE-T) supervision agreement approach is described, with emphasis on the essential elements to put in place at the outset of supervision. A written agreement, which is valuable at any supervisee developmental stage, can be invaluable when working with novice supervisees (e.g., because of the anxieties and self-doubt of first-time supervisees) and is explored with that group foremost in mind.

The paradox of international reparations

For centuries, international reparations were commonly exacted as a form of victor’s justice after war. Following World War II, however, the bitter legacy of the Treaty of Versailles and West Germany’s compensation of Nazism’s victim shifted this practice, ushering in a novel moral economy of international reparations. Yet, while recent decades have seen increased transnational activism around reparations, as well as interstate aid payments and official apologies, international reparations remain infrequent, and agreements often fail to end financial claims. This paper argues that one explanation for this lackluster record is a central paradox relating to finality. Though international reparations are designed to settle accounts and provide a basis for deeper reconciliation, by opening issues of traumatic memory to public debate, they often achieve the opposite effect and inspire a cascade of further financial claims. As evidence, we examine three cases of international reparations’ occurrence and rejection: Germany’s reparations for Nazi-era crimes, the United Nations Compensation Commission (UNCC) formation following Iraq’s invasion of Kuwait, and reparations negotiated but removed from the 1973 Paris Peace Accords. Employing process tracing methods on archival documents, we demonstrate in each case how this paradox helps explain international reparations’ limitations as a practice.

Fully invertible hyperbolic neural networks for segmenting large-scale surface and sub-surface data

The large spatial/temporal/frequency scale of geoscience and remote-sensing datasets causes memory issues when using convolutional neural networks for (sub-) surface data segmentation. Recently developed fully reversible or fully invertible networks can mostly avoid memory limitations by recomputing the states during the backward pass through the network. This results in a low and fixed memory requirement for storing network states, as opposed to the typical linear memory growth with network depth. This work focuses on a fully invertible network based on the telegraph equation. While reversibility saves the major amount of memory used in deep networks by the data, the convolutional kernels can take up most memory if fully invertible networks contain multiple invertible pooling/coarsening layers. We address the explosion of the number of convolutional kernels by combining fully invertible networks with layers that contain the convolutional kernels in a compressed form directly. A second challenge is that invertible networks output a tensor the same size as its input. This property prevents the straightforward application of invertible networks to applications that map between different input–output dimensions, need to map to outputs with more channels than present in the input data, or desire outputs that decrease/increase the resolution compared to the input data. However, we show that by employing invertible networks in a non-standard fashion, we can still use them for these tasks. Examples in hyperspectral land-use classification, airborne geophysical surveying, and seismic imaging illustrate that we can input large data volumes in one chunk and do not need to work on small patches, use dimensionality reduction, or employ methods that classify a patch to a single central pixel.

Increased Odds of Cognitive Impairment in Adults with Depressive Symptoms and Antidepressant Use.

The relationship between antidepressant use and class with cognition in depression is unclear. This study aimed to evaluate the association of cognition with depressive symptoms and antidepressant use (class, duration, number). Data from the National Health and Nutrition Examination Survey were examined for cognitive function through various tests and memory issues through the Medical Conditions questionnaire. Depressive symptoms were assessed using the Patient Health Questionnaire-9. A total of 2867 participants were included. Participants with depressive symptoms had significantly higher odds of cognitive impairment (CI) on the animal fluency test (aOR=1.89, 95% CI=1.30, 2.73, P=0.002) and Digit Symbol Substitution test (aOR=2.58, 95% CI=1.34, 4.9, P=0.007), as well as subjective memory issues (aOR=7.25, 95% CI=4.26, 12.32, P<0.001) than those without depression. There were no statistically significant associations between any of the CI categories and depressive symptoms treated with an antidepressant and antidepressant use duration. Participants who were using more than one antidepressant had significantly higher odds of subjective memory issues than those who were using one antidepressant. Specifically, users of atypical antidepressants, selective serotonin reuptake inhibitors, or tricyclic antidepressants (TCAs) had significantly higher odds of subjective memory issues in comparison to no antidepressants, with TCAs showing the largest odds (aOR=4.21, 95% CI=1.19, 14.86, P=0.028). This study highlights the relationship between depressive symptoms, antidepressant use, and CI. Future studies should further evaluate the mechanism underlying this phenomenon.

Memory architecture to mitigate side channel attacks for cryptographic application using loop cut technique

Cryptography is crucial in embedded systems for safeguarding sensitive information, maintaining data integrity, and facilitating secure communication. L1 cache memory enhances overall performance by temporarily storing cryptographic keys. Post-quantum cryptography (PQC) focuses on creating algorithms that stay secure even against quantum computing threats. However, PQC doesn't fully protect against side-channel attacks (SCA). As IoT devices like wearable health monitors and industrial sensors become more widespread, the demand for lightweight cryptography increases to balance security with resource constraints. Yet, lightweight cryptography can face challenges, including reduced security and increased susceptibility to SCA due to smaller key sizes. Attackers can exploit power consumption patterns through side-channel attacks (SCA), such as Power Analysis, to extract these secret keys. Once a key is compromised, encrypted data becomes vulnerable. In cloud computing cache side-channel attacks take advantage of multiple virtual machines running simultaneously on the same hardware, enabling them to extract sensitive information from encryption processes. Although many SRAM cells have been designed in the literature, none offer complete security against SCA. This paper presents a new architecture for secure cache memory using a proposed 10T SRAM cell that secures all three cell operations (read, write, and hold) against SCA attacks. Additionally, this architecture also prevents half selection issue in cache memory. The security measure of proposed-10T cell is 97.19 % which is highest among all other cells and reliability measure is 82.03 %.The cell also offers highest hold stability of 421 mV along with good read stability and write ability of 220 mV and 334 mV respectively. The leakage of Proposed-10T cell is also less i.e., 13.56 pA. The Performance and Security Factor (PSF) is computed for all considered cells, encompassing various performance and security metrics. The normalized PSF (PSF)N of the Proposed-10T cell is 2.17, the highest among all cells considered for comparison. Therefore, the Proposed-10T cell architecture is fully secure against SCA and achieves better performance during cell operations.

The Association of Cerebral Autoregulation Dysfunction and Postoperative Memory Impairment in Cardiac Surgery Patients.

Background and Objectives: Cardiac surgery is associated with various durations of cerebral autoregulation (CA) impairment and can significantly impact cognitive function. Cognitive functions such as memory, psychomotor speed, and attention are significantly impacted after cardiac surgery, necessitating prioritization of these areas in cognitive function tests. There is a lack of research connecting cerebral autoregulation impairment to specific cognitive function domains after cardiac surgery. This study aimed to determine if impaired cerebral autoregulation is associated with postoperative memory impairment and to test the hypothesis that the duration of this impairment affects the development of postoperative memory issues. Materials and Methods: A prospective study was conducted in 2021-2023. After approval of the Ethics Committee and with patient's written consent, 83 adult patients undergoing elective on-pump coronary artery bypass graft (CABG) surgery were enrolled. All patients were assessed for cognitive function 1 day before surgery using the Mini-Mental state examination (MMSE-2) test as a screening tool and the Hopkins Verbal Learning Test-Revised (HVLT-R) to assess memory specifically. To diagnose possible memory impairment (IM), all patients underwent a repeat assessment of cognitive function on the 7th-10th postoperative day. Cerebral autoregulation monitoring using transcranial Doppler was performed. Cerebral autoregulation status index (Mx) was recorded using Intensive Care Brain Monitoring System software, 9.1.5.23 (Cambridge, UK). Results: According to our research, the incidence of postoperative memory impairment is 30.1%. Temporary cerebral autoregulation impairment occurs in all patients undergoing elective in-pump CABG surgery. The duration of the single longest CA impairment event in seconds (LCAI) and the LCAI dose were higher in patients with postoperative memory impairment, p = 0.006 and p < 0.007, respectively. Conclusions: Cerebral autoregulation impairment is important in developing memory loss after cardiac surgery. The duration and dose of the LCAI event are predictive of postoperative memory impairment.

Everyday Memory Disturbance in Primary Progressive Aphasia

Introduction: Mounting evidence indicates distinct memory profiles among the primary progressive aphasia (PPA) variants. Neuropsychological tests reveal disproportionate memory impairments in the logopenic variant PPA (lv-PPA) relative to the non-fluent variant PPA (nfv-PPA) and semantic variant PPA (sv-PPA). The real-world experience of day-to-day memory disturbances in PPA, however, remains poorly understood. Methods: Everyday expressions of memory in 26 lv-PPA, 24 nfv-PPA, and 40 sv-PPA patients, and 70 healthy controls were examined using the Cambridge Behavioural Inventory-Revised (CBI-R) carer questionnaire. Kruskal-Wallis tests compared CBI-R Memory items (1–8) across groups. Receiver operating characteristic curves evaluated the most discriminative items to distinguish lv-PPA from nfv-PPA. Results: Compared to controls, lv-PPA and sv-PPA patients were reported to experience more day-to-day memory issues (item 1), increased repetition of questions (2), forgetting the names of familiar people and objects (4, 5), and poor concentration (6). lv-PPA patients were also reported to exhibit more occurrences of losing or misplacing items (3) and forgetting the day (7). All PPA groups experienced more confusion in unfamiliar environments (8) than controls. Direct comparisons among PPA groups revealed distinct profiles, with lv-PPA and sv-PPA patients exhibiting more frequent forgetting of names and objects (3, 4) than nfv-PPA, and sv-PPA demonstrating greater day-to-day memory impairment (1), repeated questions (2), and poor concentration (6) compared to nfv-PPA. Forgetting the names of familiar objects (5) was the most sensitive and specific item to distinguish lv-PPA from nfv-PPA. Conclusions: Our findings demonstrate distinct day-to-day memory profiles in PPA. Future research should explore the influence of language impairments on these profiles.

Anxiety's correlation with sleepiness and memory among security officers during the COVID-19 pandemic.

In the working population especially among older adults, anxiety problems have grown dramatically. This element has a significant impact on employee absenteeism and problems with physical and mental health. It was widely known that security personnel had several physical and mental difficulties during their various work hours. It is important to investigate the effects of anxiety on them. The present study aims to provide insights into the prevalence of anxiety disorders and explore the correlations between anxiety symptoms, sleep, and memory during the COVID-19 pandemic. To conduct a cross-sectional study, 42 older adult participants between the ages of sixty to seventy years were chosen and the procedure was explained.Data were gathered by giving instructions on how to complete the self-reported Generalized Anxiety Disorder Assessment -7 (GAD-7), the Epworth Sleepiness Scale, and the revised Everyday Memory Questionnaire. A total of 36 out of 42 participants (85.71%) experienced moderate to severe anxiety. Anxiety and sleep had a correlation of 0.8, while anxiety and memory had a correlation of 0.87 with a positive EMQ-R relationship. Moreover, there was a statistically significant association between sleep and memory, with a positive correlation of 0.73. The study concludes that, there is a substantial prevalence of anxiety accompanied by notable insomnia and memory problems in elderly security officers. Our findings indicate a clear relationship between sleep disturbances, memory issues, and most prevalent anxiety symptoms. These results emphasize the importance of incorporating mental health assessments and addressing an effective treatment for anxiety.

Community Senior Center Intervention to Address Factors Related to Memory Screening Engagement.

There are many individual and societal benefits to screen older adults for memory problems. Four theoretically derived psychosocial factors are predictive of dementia screening intention: perceived benefits, perceived susceptibility, self-efficacy, and knowledge about memory. The current study tested whether these factors could be modified with an educational memory screening intervention given in community senior centers. An educational presentation was designed to address these factors by increasing knowledge about memory and aging, discussing the benefits of screening and older adults' susceptibility to memory issues, and increasing self-efficacy by teaching about the memory screening process, discussing a vignette, and fielding participants' questions. The educational presentation was offered four times at three community senior centers. Quantitative data on the psychosocial factors were collected before and after the presentation from 44 older adult participants (age M = 78.70, SD = 7.21). Narrative data on satisfaction and feedback about the intervention were collected. Hierarchical linear modeling analyses were performed to measure change from pre- to post-presentation and follow-up 1 to 2 weeks after the intervention. The educational presentation effectively increased knowledge about aging memory, perceived benefits of screenings, and self-efficacy to seek screening. The presentation intervention was well received by community participants. Results provide guidance about how an intervention based in community senior centers can be refined to address factors predictive of memory screening intention in older adults.

Re-thinging Embodied and Enactive Psychiatry: A Material Engagement Approach.

Emerging consensus among enactivist philosophers and embodied mind theorists suggests that seeking to understand mental illness we need to look out of our skulls at the ecology of the brain. Still, the complex links between materiality (in broadest sense of material objects, habits, practices and environments) and mental health remain little understood. This paper discusses the benefits of adopting a material engagement approach to embodied and enactive psychiatry. We propose that the material engagement approach can change the geography of the debate over the nature of mental disorders and through that help to develop theoretical and practical insights that could improve management and treatment for various psychiatric conditions. We investigate the potential role of Material Engagement Theory (MET) in psychiatry using examples of aetiologically different mental illnesses (schizophrenia and dementia) in respect of their shared phenomenological manifestations, focusing particularly on issues of memory, self-awareness, embodiment and temporality. The effective study of socio-material relations allows better understanding of the semiotic significance and agency of specific materials, environments and technical mediations. There is unrealised potential here for creating new approaches to treatment that can broaden, challenge or complement existing interventions and practices of care.